Kelvin Yen Leonard Davis School of Gerontology University of Southern California Biography Publications Institution JoVE Articles Kelvin Yen has not added a biography. If you are Kelvin Yen and would like to personalize this page please email our Author Liaison for assistance. Publications The Mitochondrial-Derived Peptides, HumaninS14G and Small Humanin-like Peptide 2, Exhibit Chaperone-like Activity Scientific Reports. Aug, 2017 | Pubmed ID: 28798389 Hypothalamic-Pituitary Axis Regulates Hydrogen Sulfide Production Cell Metabolism. Jun, 2017 | Pubmed ID: 28591635 Mitochondrially Derived Peptides As Novel Regulators of Metabolism The Journal of Physiology. Jun, 2017 | Pubmed ID: 28574175 The Mitochondrial-derived Peptide Humanin Activates the ERK1/2, AKT, and STAT3 Signaling Pathways and Has Age-dependent Signaling Differences in the Hippocampus Oncotarget. Jul, 2016 | Pubmed ID: 27384491 Naturally Occurring Mitochondrial-derived Peptides Are Age-dependent Regulators of Apoptosis, Insulin Sensitivity, and Inflammatory Markers Aging. Apr, 2016 | Pubmed ID: 27070352 The Mitochondrial-Derived Peptide Humanin Protects RPE Cells From Oxidative Stress, Senescence, and Mitochondrial Dysfunction Investigative Ophthalmology & Visual Science. Mar, 2016 | Pubmed ID: 26990160 Uncoupling Lifespan and Healthspan in Caenorhabditis Elegans Longevity Mutants Proceedings of the National Academy of Sciences of the United States of America. Jan, 2015 | Pubmed ID: 25561524 IGF-I Regulates the Age-dependent Signaling Peptide Humanin Aging Cell. Oct, 2014 | Pubmed ID: 25040290 Humanin: a Harbinger of Mitochondrial-derived Peptides? Trends in Endocrinology and Metabolism: TEM. May, 2013 | Pubmed ID: 23402768 The Emerging Role of the Mitochondrial-derived Peptide Humanin in Stress Resistance Journal of Molecular Endocrinology. Feb, 2013 | Pubmed ID: 23239898 Hypothalamic Fkbp51 is Induced by Fasting, and Elevated Hypothalamic Expression Promotes Obese Phenotypes American Journal of Physiology. Endocrinology and Metabolism. Apr, 2012 | Pubmed ID: 22318949 FDA-approved Drugs That Protect Mammalian Neurons from Glucose Toxicity Slow Aging Dependent on Cbp and Protect Against Proteotoxicity PloS One. 2011 | Pubmed ID: 22114686 PDP-1 Links the TGF-β and IIS Pathways to Regulate Longevity, Development, and Metabolism PLoS Genetics. Apr, 2011 | Pubmed ID: 21533078 DAF-16/Forkhead Box O Transcription Factor: Many Paths to a Single Fork(head) in the Road Antioxidants & Redox Signaling. Feb, 2011 | Pubmed ID: 20673162 A Comparative Study of Fat Storage Quantitation in Nematode Caenorhabditis Elegans Using Label and Label-free Methods PloS One. Sep, 2010 | Pubmed ID: 20862331 A New DAF-16 Isoform Regulates Longevity Nature. Jul, 2010 | Pubmed ID: 20613724 Evidence for Only Two Independent Pathways for Decreasing Senescence in Caenorhabditis Elegans Age (Dordrecht, Netherlands). Mar, 2010 | Pubmed ID: 19662517 Role of CBP and SATB-1 in Aging, Dietary Restriction, and Insulin-like Signaling PLoS Biology. Nov, 2009 | Pubmed ID: 19924292 Converging Pathways in Lifespan Regulation Current Biology : CB. Aug, 2009 | Pubmed ID: 19674551 SOD Isoforms Play No Role in Lifespan in Ad Lib or Dietary Restricted Conditions, but Mutational Inactivation of SOD-1 Reduces Life Extension by Cold Mechanisms of Ageing and Development. Mar, 2009 | Pubmed ID: 19059428 Validated Analysis of Mortality Rates Demonstrates Distinct Genetic Mechanisms That Influence Lifespan Experimental Gerontology. Dec, 2008 | Pubmed ID: 18832022 Chemosensory and Caloric Mechanisms Influence Distinct Components of Mortality Rate Experimental Gerontology. Dec, 2008 | Pubmed ID: 18790043 Low-carbohydrate Diets Cause Obesity, Low-carbohydrate Diets Reverse Obesity: a Metabolic Mechanism Resolving the Paradox Appetite. Mar, 2007 | Pubmed ID: 17141367 Secrets of the Lac Operon. Glucose Hysteresis As a Mechanism in Dietary Restriction, Aging and Disease Interdisciplinary Topics in Gerontology. 2007 | Pubmed ID: 17063032 Impaired Glucose Signaling As a Cause of Obesity and the Metabolic Syndrome: the Glucoadipostatic Hypothesis Physiology & Behavior. May, 2005 | Pubmed ID: 15924903 Lifespan is Not Determined by Metabolic Rate: Evidence from Fishes and C. Elegans Experimental Gerontology. Jun, 2004 | Pubmed ID: 15217699 Mining Microarrays for Metabolic Meaning: Nutritional Regulation of Hypothalamic Gene Expression Neurochemical Research. Jun, 2004 | Pubmed ID: 15176466 Fraccionamento subcelular para activação de ERK tratamento de peptídeo derivado mitocondrial Su-Jeong Kim1, Jialin Xiao1, Pinchas Cohen1, Kelvin Yen1 1Leonard Davis School of Gerontology, University of Southern California JoVE 56496 Biology
Fraccionamento subcelular para activação de ERK tratamento de peptídeo derivado mitocondrial Su-Jeong Kim1, Jialin Xiao1, Pinchas Cohen1, Kelvin Yen1 1Leonard Davis School of Gerontology, University of Southern California JoVE 56496 Biology