Pinchas Cohen Leonard Davis School of Gerontology University of Southern California Biography Publications Institution JoVE Articles Pinchas Cohen has not added a biography. If you are Pinchas Cohen and would like to personalize this page please email our Author Liaison for assistance. Publications The Mitochondrial-Derived Peptides, HumaninS14G and Small Humanin-like Peptide 2, Exhibit Chaperone-like Activity Scientific Reports. Aug, 2017 | Pubmed ID: 28798389 Humanin G (HNG) Protects Age-related Macular Degeneration (AMD) Transmitochondrial ARPE-19 Cybrids from Mitochondrial and Cellular Damage Cell Death & Disease. Jul, 2017 | Pubmed ID: 28726777 The GH Receptor Exon 3 Deletion is a Marker of Male-specific Exceptional Longevity Associated with Increased GH Sensitivity and Taller Stature Science Advances. Jun, 2017 | Pubmed ID: 28630896 Feeling Misguided: a Comment on the US Guidelines on Growth Hormone and Insulin-like Growth Factor-I Treatment in Children and Adolescents Current Opinion in Pediatrics. Aug, 2017 | Pubmed ID: 28604412 Hypothalamic-Pituitary Axis Regulates Hydrogen Sulfide Production Cell Metabolism. Jun, 2017 | Pubmed ID: 28591635 Mitochondrially Derived Peptides As Novel Regulators of Metabolism The Journal of Physiology. Jun, 2017 | Pubmed ID: 28574175 Mitochondrial DNA Hypomethylation Is a Biomarker Associated with Induced Senescence in Human Fetal Heart Mesenchymal Stem Cells Stem Cells International. 2017 | Pubmed ID: 28484495 Fasting-Mimicking Diet Promotes Ngn3-Driven β-Cell Regeneration to Reverse Diabetes Cell. Feb, 2017 | Pubmed ID: 28235195 Fasting-mimicking Diet and Markers/risk Factors for Aging, Diabetes, Cancer, and Cardiovascular Disease Science Translational Medicine. Feb, 2017 | Pubmed ID: 28202779 Effects of Prolonged GRP78 Haploinsufficiency on Organ Homeostasis, Behavior, Cancer and Chemotoxic Resistance in Aged Mice Scientific Reports. Feb, 2017 | Pubmed ID: 28145503 Humanin Protects RPE Cells from Endoplasmic Reticulum Stress-Induced Apoptosis by Upregulation of Mitochondrial Glutathione PloS One. 2016 | Pubmed ID: 27783653 Lower Circulating Insulin-like Growth Factor-I is Associated with Better Cognition in Females with Exceptional Longevity Without Compromise to Muscle Mass and Function Aging. Oct, 2016 | Pubmed ID: 27744417 The Mitochondrial-derived Peptide Humanin Activates the ERK1/2, AKT, and STAT3 Signaling Pathways and Has Age-dependent Signaling Differences in the Hippocampus Oncotarget. Jul, 2016 | Pubmed ID: 27384491 Effect of Dietary Omega-3 Fatty Acids on Tumor-Associated Macrophages and Prostate Cancer Progression The Prostate. Oct, 2016 | Pubmed ID: 27338236 Effects of Sex, Strain, and Energy Intake on Hallmarks of Aging in Mice Cell Metabolism. Jun, 2016 | Pubmed ID: 27304509 Safety and Feasibility of Fasting in Combination with Platinum-based Chemotherapy BMC Cancer. Jun, 2016 | Pubmed ID: 27282289 MOTS-c: A Novel Mitochondrial-derived Peptide Regulating Muscle and Fat Metabolism Free Radical Biology & Medicine. Nov, 2016 | Pubmed ID: 27216708 Naturally Occurring Mitochondrial-derived Peptides Are Age-dependent Regulators of Apoptosis, Insulin Sensitivity, and Inflammatory Markers Aging. Apr, 2016 | Pubmed ID: 27070352 Growth Hormone Research Society Perspective on the Development of Long-acting Growth Hormone Preparations European Journal of Endocrinology. Jun, 2016 | Pubmed ID: 27009113 The Mitochondrial-Derived Peptide Humanin Protects RPE Cells From Oxidative Stress, Senescence, and Mitochondrial Dysfunction Investigative Ophthalmology & Visual Science. Mar, 2016 | Pubmed ID: 26990160 Central Insulin-like Growth Factor-1 (IGF-1) Restores Whole-body Insulin Action in a Model of Age-related Insulin Resistance and IGF-1 Decline Aging Cell. Feb, 2016 | Pubmed ID: 26534869 The Potent Humanin Analogue (HNG) Protects Germ Cells and Leucocytes While Enhancing Chemotherapy-Induced Suppression of Cancer Metastases in Male Mice Endocrinology. Dec, 2015 | Pubmed ID: 26384090 Status of Long-acting-growth Hormone Preparations--2015 Growth Hormone & IGF Research : Official Journal of the Growth Hormone Research Society and the International IGF Research Society. Oct, 2015 | Pubmed ID: 26187188 Rat Humanin is Encoded and Translated in Mitochondria and is Localized to the Mitochondrial Compartment Where It Regulates ROS Production Molecular and Cellular Endocrinology. Sep, 2015 | Pubmed ID: 26116236 A Periodic Diet That Mimics Fasting Promotes Multi-System Regeneration, Enhanced Cognitive Performance, and Healthspan Cell Metabolism. Jul, 2015 | Pubmed ID: 26094889 The Mitochondrial-derived Peptide MOTS-c Promotes Metabolic Homeostasis and Reduces Obesity and Insulin Resistance Cell Metabolism. Mar, 2015 | Pubmed ID: 25738459 The Effects of Humanin and Its Analogues on Male Germ Cell Apoptosis Induced by Chemotherapeutic Drugs Apoptosis : an International Journal on Programmed Cell Death. Apr, 2015 | Pubmed ID: 25666707 The Effect of Sex on Humanin Levels in Healthy Adults and Patients with Uncomplicated Type 1 Diabetes Mellitus Canadian Journal of Physiology and Pharmacology. Apr, 2015 | Pubmed ID: 25615723 IGF-I Regulates the Age-dependent Signaling Peptide Humanin Aging Cell. Oct, 2014 | Pubmed ID: 25040290 Low Insulin-like Growth Factor-1 Level Predicts Survival in Humans with Exceptional Longevity Aging Cell. Aug, 2014 | Pubmed ID: 24618355 Low Protein Intake is Associated with a Major Reduction in IGF-1, Cancer, and Overall Mortality in the 65 and Younger but Not Older Population Cell Metabolism. Mar, 2014 | Pubmed ID: 24606898 New Role for the Mitochondrial Peptide Humanin: Protective Agent Against Chemotherapy-induced Side Effects Journal of the National Cancer Institute. Mar, 2014 | Pubmed ID: 24586106 IGF1R Blockade with Ganitumab Results in Systemic Effects on the GH-IGF Axis in Mice The Journal of Endocrinology. Apr, 2014 | Pubmed ID: 24492468 Dose-sparing and Safety-enhancing Effects of an IGF-I-based Dosing Regimen in Short Children Treated with Growth Hormone in a 2-year Randomized Controlled Trial: Therapeutic and Pharmacoeconomic Considerations Clinical Endocrinology. Jul, 2014 | Pubmed ID: 24428305 Effect of a Low-fat Fish Oil Diet on Proinflammatory Eicosanoids and Cell-cycle Progression Score in Men Undergoing Radical Prostatectomy Cancer Prevention Research (Philadelphia, Pa.). Jan, 2014 | Pubmed ID: 24169960 Pharmacokinetics and Tissue Distribution of Humanin and Its Analogues in Male Rodents Endocrinology. Oct, 2013 | Pubmed ID: 23836030 Effects of Calorie Restriction and IGF-1 Receptor Blockade on the Progression of 22Rv1 Prostate Cancer Xenografts International Journal of Molecular Sciences. Jul, 2013 | Pubmed ID: 23823800 Prepubertal Children with Growth Hormone Deficiency Treated for Four Years with Growth Hormone Experience Dose-dependent Increase in Height, but Not in the Rate of Puberty Initiation Hormone Research in Paediatrics. 2013 | Pubmed ID: 23816571 Response of the Insulin-like Growth Factor (IGF) System to IGF-IR Inhibition and Androgen Deprivation in a Neoadjuvant Prostate Cancer Trial: Effects of Obesity and Androgen Deprivation The Journal of Clinical Endocrinology and Metabolism. May, 2013 | Pubmed ID: 23533230 Humanin: a Harbinger of Mitochondrial-derived Peptides? Trends in Endocrinology and Metabolism: TEM. May, 2013 | Pubmed ID: 23402768 Protein Restriction Cycles Reduce IGF-1 and Phosphorylated Tau, and Improve Behavioral Performance in an Alzheimer's Disease Mouse Model Aging Cell. Apr, 2013 | Pubmed ID: 23362919 The Emerging Role of the Mitochondrial-derived Peptide Humanin in Stress Resistance Journal of Molecular Endocrinology. Feb, 2013 | Pubmed ID: 23239898 Resveratrol Worsens Survival in SCID Mice with Prostate Cancer Xenografts in a Cell-line Specific Manner, Through Paradoxical Effects on Oncogenic Pathways The Prostate. May, 2013 | Pubmed ID: 23192356 Growth Hormone Receptor (GHR) Exon 3 Polymorphism Status Detection by Dual-enzyme-linked Immunosorbent Assay (ELISA) The Journal of Clinical Endocrinology and Metabolism. Jan, 2013 | Pubmed ID: 23162096 IGFBP-3 Nuclear Localization Predicts Human Prostate Cancer Recurrence Hormones & Cancer. Feb, 2013 | Pubmed ID: 23011725 Efficacy of IGF-based Growth Hormone (GH) Dosing in NonGH-deficient (nonGHD) Short Stature Children with Low IGF-I is Not Related to Basal IGF-I Levels Clinical Endocrinology. Mar, 2013 | Pubmed ID: 22924571 Humanin Prevents Intra-renal Microvascular Remodeling and Inflammation in Hypercholesterolemic ApoE Deficient Mice Life Sciences. Sep, 2012 | Pubmed ID: 22820173 Effect of a Low-fat Diet Combined with IGF-1 Receptor Blockade on 22Rv1 Prostate Cancer Xenografts Molecular Cancer Therapeutics. Jul, 2012 | Pubmed ID: 22562985 Humanin, a Cytoprotective Peptide, is Expressed in Carotid Atherosclerotic [corrected] Plaques in Humans PloS One. 2012 | Pubmed ID: 22328926 Long-term Surveillance of Growth Hormone Therapy The Journal of Clinical Endocrinology and Metabolism. Jan, 2012 | Pubmed ID: 22174422 How Useful Are Serum IGF-I Measurements for Managing GH Replacement Therapy in Adults and Children? Pituitary. Jun, 2012 | Pubmed ID: 21909971 Phase II Prospective Randomized Trial of a Low-fat Diet with Fish Oil Supplementation in Men Undergoing Radical Prostatectomy Cancer Prevention Research (Philadelphia, Pa.). Dec, 2011 | Pubmed ID: 22027686 Global Igfbp1 Deletion Does Not Affect Prostate Cancer Development in a C-Myc Transgenic Mouse Model The Journal of Endocrinology. Dec, 2011 | Pubmed ID: 21903863 Insulin-like Growth Factor (IGF)-I and IGF-II Contribute Differentially to the Phenotype of Pregnancy Associated Plasma Protein-A Knock-out Mice Growth Hormone & IGF Research : Official Journal of the Growth Hormone Research Society and the International IGF Research Society. Oct, 2011 | Pubmed ID: 21802327 Humanin Preserves Endothelial Function and Prevents Atherosclerotic Plaque Progression in Hypercholesterolemic ApoE Deficient Mice Atherosclerosis. Nov, 2011 | Pubmed ID: 21763658 IGFBP-3 is a Metastasis Suppression Gene in Prostate Cancer Cancer Research. Aug, 2011 | Pubmed ID: 21697285 Growth Hormone Receptor Deficiency is Associated with a Major Reduction in Pro-aging Signaling, Cancer, and Diabetes in Humans Science Translational Medicine. Feb, 2011 | Pubmed ID: 21325617 Endocrine Actions of Myostatin: Systemic Regulation of the IGF and IGF Binding Protein Axis Endocrinology. Jan, 2011 | Pubmed ID: 21147879 Chemoprevention of Prostate Cancer with Lycopene in the TRAMP Model The Prostate. Oct, 2010 | Pubmed ID: 20687227 Humanin is Expressed in Human Vascular Walls and Has a Cytoprotective Effect Against Oxidized LDL-induced Oxidative Stress Cardiovascular Research. Nov, 2010 | Pubmed ID: 20562421 Variable Degree of Growth Hormone (GH) and Insulin-like Growth Factor (IGF) Sensitivity in Children with Idiopathic Short Stature Compared with GH-deficient Patients: Evidence from an IGF-based Dosing Study of Short Children The Journal of Clinical Endocrinology and Metabolism. May, 2010 | Pubmed ID: 20207829 Effect of Intermittent Fasting with or Without Caloric Restriction on Prostate Cancer Growth and Survival in SCID Mice The Prostate. Jul, 2010 | Pubmed ID: 20166128 Reduced Levels of IGF-I Mediate Differential Protection of Normal and Cancer Cells in Response to Fasting and Improve Chemotherapeutic Index Cancer Research. Feb, 2010 | Pubmed ID: 20145127 Opposing Roles of Insulin-like Growth Factor Binding Protein 3 and Humanin in the Regulation of Testicular Germ Cell Apoptosis Endocrinology. Jan, 2010 | Pubmed ID: 19952275 Growth Inhibitory Effect of Low Fat Diet on Prostate Cancer Cells: Results of a Prospective, Randomized Dietary Intervention Trial in Men with Prostate Cancer The Journal of Urology. Jan, 2010 | Pubmed ID: 19914662 Interaction of Insulin-like Growth Factor-binding Protein-3 and BAX in Mitochondria Promotes Male Germ Cell Apoptosis The Journal of Biological Chemistry. Jan, 2010 | Pubmed ID: 19887447 Pomegranate Extract Induces Apoptosis in Human Prostate Cancer Cells by Modulation of the IGF-IGFBP Axis Growth Hormone & IGF Research : Official Journal of the Growth Hormone Research Society and the International IGF Research Society. Feb, 2010 | Pubmed ID: 19853487 The Neurosurvival Factor Humanin Inhibits Beta-cell Apoptosis Via Signal Transducer and Activator of Transcription 3 Activation and Delays and Ameliorates Diabetes in Nonobese Diabetic Mice Metabolism: Clinical and Experimental. Mar, 2010 | Pubmed ID: 19800083 Fasting and Cancer Treatment in Humans: A Case Series Report Aging. Dec, 2009 | Pubmed ID: 20157582 Clinical Management of Growth Hormone Therapy for Children Managed Care (Langhorne, Pa.). Aug, 2009 | Pubmed ID: 19760983 Growth Hormone Treatment: Evidence, Practice, and Emerging Issues Managed Care (Langhorne, Pa.). Aug, 2009 | Pubmed ID: 19760982 Humanin: a Novel Central Regulator of Peripheral Insulin Action PloS One. 2009 | Pubmed ID: 19623253 Enhancing the Apoptotic Potential of Insulin-like Growth Factor-binding Protein-3 in Prostate Cancer by Modulation of CK2 Phosphorylation Molecular Endocrinology (Baltimore, Md.). Oct, 2009 | Pubmed ID: 19556345 The Effects of Varying Dietary Carbohydrate and Fat Content on Survival in a Murine LNCaP Prostate Cancer Xenograft Model Cancer Prevention Research (Philadelphia, Pa.). Jun, 2009 | Pubmed ID: 19470786 Liver-specific Deletion of the Growth Hormone Receptor Reveals Essential Role of Growth Hormone Signaling in Hepatic Lipid Metabolism The Journal of Biological Chemistry. Jul, 2009 | Pubmed ID: 19460757 Optimizing Growth Hormone Dosing in Children with Idiopathic Short Stature Hormone Research. Jan, 2009 | Pubmed ID: 19153511 PAPA-1 Is a Nuclear Binding Partner of IGFBP-2 and Modulates Its Growth-promoting Actions Molecular Endocrinology (Baltimore, Md.). Feb, 2009 | Pubmed ID: 19095771 Serum Complexes of Insulin-like Growth Factor-1 Modulate Skeletal Integrity and Carbohydrate Metabolism FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Mar, 2009 | Pubmed ID: 18952711 Surprising New Height Regulating Genes: Beyond Growth Hormone and IGF-I Pediatric Research. Nov, 2008 | Pubmed ID: 18931612 Lost in Translation? Pediatric Research. Sep, 2008 | Pubmed ID: 18714199 Homeostatic Imbalance Between Apoptosis and Cell Renewal in the Liver of Premature Aging Xpd Mice PloS One. Jun, 2008 | Pubmed ID: 18545656 Targeted Deletion of Hepatic Igf1 in TRAMP Mice Leads to Dramatic Alterations in the Circulating Insulin-like Growth Factor Axis but Does Not Reduce Tumor Progression Cancer Research. May, 2008 | Pubmed ID: 18451161 Statement 1: a Serum Insulin-like Growth Factor I (IGF-I) Level Should Be Part of the Evaluation of Children with Short Stature Pediatric Endocrinology Reviews : PER. Apr, 2008 | Pubmed ID: 18438325 Effect of Low-fat Diet on Development of Prostate Cancer and Akt Phosphorylation in the Hi-Myc Transgenic Mouse Model Cancer Research. Apr, 2008 | Pubmed ID: 18413778 SnoRNA Snord116 (Pwcr1/MBII-85) Deletion Causes Growth Deficiency and Hyperphagia in Mice PloS One. Mar, 2008 | Pubmed ID: 18320030 Functionally Significant Insulin-like Growth Factor I Receptor Mutations in Centenarians Proceedings of the National Academy of Sciences of the United States of America. Mar, 2008 | Pubmed ID: 18316725 Carbohydrate Restriction, Prostate Cancer Growth, and the Insulin-like Growth Factor Axis The Prostate. Jan, 2008 | Pubmed ID: 17999389 Quantitative Ontogeny of Murine Insulin-like Growth Factor (IGF)-I, IGF-binding Protein-3 and the IGF-related Acid-labile Subunit Growth Hormone & IGF Research : Official Journal of the Growth Hormone Research Society and the International IGF Research Society. Feb, 2008 | Pubmed ID: 17719253 Dietary Feeding of Silibinin Inhibits Prostate Tumor Growth and Progression in Transgenic Adenocarcinoma of the Mouse Prostate Model Cancer Research. Nov, 2007 | Pubmed ID: 18006855 The Somatomedin Hypothesis 2007: 50 Years Later The Journal of Clinical Endocrinology and Metabolism. Dec, 2007 | Pubmed ID: 17986643 A Mechanism to Explain How Regular Exercise Might Reduce the Risk for Clinical Prostate Cancer European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP). Oct, 2007 | Pubmed ID: 17923812 Spinal Bone Mineral Density, IGF-1 and IGFBP-3 in Children with Cerebral Palsy Hormone Research. 2007 | Pubmed ID: 17912004 Treatment Perspectives in Idiopathic Short Stature with a Focus on IGF-I Deficiency Pediatric Endocrinology Reviews : PER. May, 2007 | Pubmed ID: 17581497 Hormonal Regulation of IGFBP-2 Proteolysis is Attenuated with Progression to Androgen Insensitivity in the LNCaP Progression Model Journal of Cellular Physiology. Oct, 2007 | Pubmed ID: 17492783 Contribution of the Orphan Nuclear Receptor Nur77 to the Apoptotic Action of IGFBP-3 Carcinogenesis. Aug, 2007 | Pubmed ID: 17434920 Insulin Growth Factor-based Dosing of Growth Hormone Therapy in Children: a Randomized, Controlled Study The Journal of Clinical Endocrinology and Metabolism. Jul, 2007 | Pubmed ID: 17356043 Insulin-like Growth Factor Binding Protein-3 Induces Insulin Resistance in Adipocytes in Vitro and in Rats in Vivo Pediatric Research. Feb, 2007 | Pubmed ID: 17237715 Growth Hormone Therapy Improves Bone Mineral Density in Children with Cerebral Palsy: a Preliminary Pilot Study The Journal of Clinical Endocrinology and Metabolism. Mar, 2007 | Pubmed ID: 17179200 Phosphorylation by DNA-dependent Protein Kinase is Critical for Apoptosis Induction by Insulin-like Growth Factor Binding Protein-3 Cancer Research. Nov, 2006 | Pubmed ID: 17108124 Central and Opposing Effects of IGF-I and IGF-binding Protein-3 on Systemic Insulin Action Diabetes. Oct, 2006 | Pubmed ID: 17003344 Controversy in Clinical Endocrinology: Problems with Reclassification of Insulin-like Growth Factor I Production and Action Disorders The Journal of Clinical Endocrinology and Metabolism. Nov, 2006 | Pubmed ID: 16954153 Effect of Altering Dietary Omega-6/omega-3 Fatty Acid Ratios on Prostate Cancer Membrane Composition, Cyclooxygenase-2, and Prostaglandin E2 Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Aug, 2006 | Pubmed ID: 16899616 Advances in Pediatric Growth Hormone Therapy: IGF-I-based Dosing Indian Pediatrics. Jul, 2006 | Pubmed ID: 16891676 The Ternary IGF Complex Influences Postnatal Bone Acquisition and the Skeletal Response to Intermittent Parathyroid Hormone The Journal of Endocrinology. May, 2006 | Pubmed ID: 16648296 Anti-apoptotic Factor Humanin is Expressed in the Testis and Prevents Cell-death in Leydig Cells During the First Wave of Spermatogenesis Journal of Cellular Physiology. Aug, 2006 | Pubmed ID: 16619233 Insulin-like Growth Factor Binding Protein-3: Insulin-like Growth Factor Independence Comes of Age Endocrinology. May, 2006 | Pubmed ID: 16617154 Insulin-like Growth Factor Binding Protein 3 As an Anticancer Molecule in Ewing's Sarcoma International Journal of Cancer. Sep, 2006 | Pubmed ID: 16570284 Overview of the IGF-I System Hormone Research. 2006 | Pubmed ID: 16508327 Ribonucleic Acid Polymerase II Binding Subunit 3 (Rpb3), a Potential Nuclear Target of Insulin-like Growth Factor Binding Protein-3 Endocrinology. May, 2006 | Pubmed ID: 16455777 Identification of Insulin-like Growth Factor Binding Protein-3 As a Farnesyl Transferase Inhibitor SCH66336-induced Negative Regulator of Angiogenesis in Head and Neck Squamous Cell Carcinoma Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jan, 2006 | Pubmed ID: 16428512 Racial Differences in Prognostic Value of Adult Height for Biochemical Progression Following Radical Prostatectomy Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Nov, 2005 | Pubmed ID: 16278394 The Role of the Insulin-like Growth Factor System in Prenatal Growth Molecular Genetics and Metabolism. Sep-Oct, 2005 | Pubmed ID: 16165387 Control of Aging and Longevity by IGF-I Signaling Experimental Gerontology. Nov, 2005 | Pubmed ID: 16154307 Insulin-like Growth Factor I (IGF-I) Measurements in Growth Hormone (GH) Therapy of Idiopathic Short Stature (ISS) Growth Hormone & IGF Research : Official Journal of the Growth Hormone Research Society and the International IGF Research Society. Jul, 2005 | Pubmed ID: 16039893 Combination Therapy of Insulin-like Growth Factor Binding Protein-3 and Retinoid X Receptor Ligands Synergize on Prostate Cancer Cell Apoptosis in Vitro and in Vivo Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jul, 2005 | Pubmed ID: 16000583 Pharmacodynamic Considerations with Recombinant Human Insulin-like Growth Factor-I in Children Hormone Research. 2005 | Pubmed ID: 15886488 P53-Dependent and P53-independent Induction of Insulin-like Growth Factor Binding Protein-3 by Deoxyribonucleic Acid Damage and Hypoxia The Journal of Clinical Endocrinology and Metabolism. Jun, 2005 | Pubmed ID: 15769996 Rapid Apoptosis Induction by IGFBP-3 Involves an Insulin-like Growth Factor-independent Nucleomitochondrial Translocation of RXRalpha/Nur77 The Journal of Biological Chemistry. Apr, 2005 | Pubmed ID: 15731112 Overexpression of Gly56/gly80/gly81-mutant Insulin-like Growth Factor-binding Protein-3 in Transgenic Mice Endocrinology. Mar, 2005 | Pubmed ID: 15550509 Allelic Differences in a Quantitative Trait Locus Affecting Insulin-like Growth Factor-I Impact Skeletal Acquisition and Body Composition Pediatric Nephrology (Berlin, Germany). Mar, 2005 | Pubmed ID: 15549416 The Role of Insulin-like Growth Factor I Monitoring in Growth Hormone-treated Children Hormone Research. 2004 | Pubmed ID: 15761234 Is Treatment with Growth Hormone Effective in Children with Cerebral Palsy? Developmental Medicine and Child Neurology. Aug, 2004 | Pubmed ID: 15287249 EWS/FLI-1 Silencing and Gene Profiling of Ewing Cells Reveal Downstream Oncogenic Pathways and a Crucial Role for Repression of Insulin-like Growth Factor Binding Protein 3 Molecular and Cellular Biology. Aug, 2004 | Pubmed ID: 15282325 Insulin-like Growth Factor Binding Protein-3 is a Novel Mediator of Apoptosis in Insulin-secreting Cells Growth Hormone & IGF Research : Official Journal of the Growth Hormone Research Society and the International IGF Research Society. Jun, 2004 | Pubmed ID: 15125883 Phenotypic Effects of Leptin Replacement on Morbid Obesity, Diabetes Mellitus, Hypogonadism, and Behavior in Leptin-deficient Adults Proceedings of the National Academy of Sciences of the United States of America. Mar, 2004 | Pubmed ID: 15070752 Insulin-like Growth Factor Binding Protein-3 Antagonizes the Effects of Retinoids in Myeloid Leukemia Cells Blood. Jul, 2004 | Pubmed ID: 15026318 Cellular Internalization of Insulin-like Growth Factor Binding Protein-3: Distinct Endocytic Pathways Facilitate Re-uptake and Nuclear Localization The Journal of Biological Chemistry. Jan, 2004 | Pubmed ID: 14576164 A Functional Genomics Approach for the Identification of Putative Tumor Suppressor Genes: Dickkopf-1 As Suppressor of HeLa Cell Transformation Carcinogenesis. Jan, 2004 | Pubmed ID: 14555616 Insulin-like Growth Factors and Their Binding Proteins in Children Born Small for Gestational Age: Implication for Growth Hormone Therapy Hormone Research. 2003 | Pubmed ID: 14671408 Update of Guidelines for the Use of Growth Hormone in Children: the Lawson Wilkins Pediatric Endocrinology Society Drug and Therapeutics Committee The Journal of Pediatrics. Oct, 2003 | Pubmed ID: 14571209 Interaction Between the Alzheimer's Survival Peptide Humanin and Insulin-like Growth Factor-binding Protein 3 Regulates Cell Survival and Apoptosis Proceedings of the National Academy of Sciences of the United States of America. Oct, 2003 | Pubmed ID: 14561895 Effect of Isocaloric Low-fat Diet on Human LAPC-4 Prostate Cancer Xenografts in Severe Combined Immunodeficient Mice and the Insulin-like Growth Factor Axis Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jul, 2003 | Pubmed ID: 12855654 Insulin-like Growth Factor I Stimulates Telomerase Activity in Prostate Cancer Cells The Journal of Clinical Endocrinology and Metabolism. Jul, 2003 | Pubmed ID: 12843187 Individualized Growth Hormone Therapy in Children: Advances Beyond Weight-based Dosing Journal of Pediatric Endocrinology & Metabolism : JPEM. May, 2003 | Pubmed ID: 12795364 Insulin-like Growth Factor I (IGF-I) and IGF Binding Protein-1 Modulate Prostate Cancer Cell Growth and Apoptosis: Possible Mediators for the Effects of Diet and Exercise on Cancer Cell Survival Endocrinology. Jun, 2003 | Pubmed ID: 12746292 Type Ialpha Collagen is an IGFBP-3 Binding Protein Growth Hormone & IGF Research : Official Journal of the Growth Hormone Research Society and the International IGF Research Society. Apr-Jun, 2003 | Pubmed ID: 12735930 Novel Stimulatory Role for Insulin-like Growth Factor Binding Protein-2 in Prostate Cancer Cells International Journal of Cancer. May, 2003 | Pubmed ID: 12672024 Rapid Insulin-like Growth Factor (IGF)-independent Effects of IGF Binding Protein-3 on Endothelial Cell Survival The Journal of Clinical Endocrinology and Metabolism. Feb, 2003 | Pubmed ID: 12574231 Effect of Diet and Exercise on Serum Insulin, IGF-I, and IGFBP-1 Levels and Growth of LNCaP Cells in Vitro (United States) Cancer Causes & Control : CCC. Dec, 2002 | Pubmed ID: 12588089 IGFs and IGFBPs: Role in Health and Disease Best Practice & Research. Clinical Endocrinology & Metabolism. Sep, 2002 | Pubmed ID: 12464227 Association Between the Insulin Resistance of Puberty and the Insulin-like Growth Factor-I/growth Hormone Axis The Journal of Clinical Endocrinology and Metabolism. Oct, 2002 | Pubmed ID: 12364479 Diagnosis and Management of Growth Hormone Deficiency in Childhood and Adolescence--part 2: Growth Hormone Treatment in Growth Hormone Deficient Children Growth Hormone & IGF Research : Official Journal of the Growth Hormone Research Society and the International IGF Research Society. Oct, 2002 | Pubmed ID: 12213187 IGFBP-3 Mediates P53-induced Apoptosis During Serum Starvation International Journal of Oncology. Aug, 2002 | Pubmed ID: 12118329 Insulin-like Growth Factor Binding Protein-3 Inhibits the Growth of Non-small Cell Lung Cancer Cancer Research. Jun, 2002 | Pubmed ID: 12068000 Insulin-like Growth Factor Binding Protein-3 Mediates Tumor Necrosis Factor-alpha-induced Apoptosis: Role of Bcl-2 Phosphorylation Cell Growth & Differentiation : the Molecular Biology Journal of the American Association for Cancer Research. Apr, 2002 | Pubmed ID: 11971816 Effects of Dose and Gender on the Growth and Growth Factor Response to GH in GH-deficient Children: Implications for Efficacy and Safety The Journal of Clinical Endocrinology and Metabolism. Jan, 2002 | Pubmed ID: 11788629 Fraccionamento subcelular para activação de ERK tratamento de peptídeo derivado mitocondrial Su-Jeong Kim1, Jialin Xiao1, Pinchas Cohen1, Kelvin Yen1 1Leonard Davis School of Gerontology, University of Southern California JoVE 56496 Biology
Fraccionamento subcelular para activação de ERK tratamento de peptídeo derivado mitocondrial Su-Jeong Kim1, Jialin Xiao1, Pinchas Cohen1, Kelvin Yen1 1Leonard Davis School of Gerontology, University of Southern California JoVE 56496 Biology