Krzysztof Pyrc Malopolska Centre of Biotechnology Jagiellonian University Biography Publications Institution JoVE Articles Krzysztof Pyrc has not added a biography. If you are Krzysztof Pyrc and would like to personalize this page please email our Author Liaison for assistance. Publications The SARS-CoV-2 ORF10 is Not Essential in Vitro or in Vivo in Humans PLoS Pathogens. Dec, 2020 | Pubmed ID: 33301543 Battle at the Entrance Gate: CIITA As a Weapon to Prevent the Internalization of SARS-CoV-2 and Ebola Viruses Signal Transduction and Targeted Therapy. 11, 2020 | Pubmed ID: 33235189 Kallikrein 13 Serves As a Priming Protease During Infection by the Human Coronavirus HKU1 Science Signaling. 11, 2020 | Pubmed ID: 33234691 HTCC As a Polymeric Inhibitor of SARS-CoV-2 and MERS-CoV Journal of Virology. Nov, 2020 | Pubmed ID: 33219167 Electrochemical Immunosensors Based on Screen-Printed Gold and Glassy Carbon Electrodes: Comparison of Performance for Respiratory Syncytial Virus Detection Biosensors. Nov, 2020 | Pubmed ID: 33202922 In Vitro Inhibition of Zika Virus Replication with Poly(Sodium 4-Styrenesulfonate) Viruses. 08, 2020 | Pubmed ID: 32842540 Visualizing Coronavirus Entry into Cells Methods in Molecular Biology (Clifton, N.J.). 2020 | Pubmed ID: 32833217 Effectiveness of Lung Transplantation in Patients With Interstitial Lung Diseases Transplantation Proceedings. Sep, 2020 | Pubmed ID: 32571712 Effects of Host Genetic Variations on Response To, Susceptibility and Severity of Respiratory Infections Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. Aug, 2020 | Pubmed ID: 32480226 Altered Cytokine Levels and Immune Responses in Patients with SARS-CoV-2 Infection and Related Conditions Cytokine. 09, 2020 | Pubmed ID: 32460144 Replication of Severe Acute Respiratory Syndrome Coronavirus 2 in Human Respiratory Epithelium Journal of Virology. 07, 2020 | Pubmed ID: 32434888 Angiotensin Converting Enzyme: A Review on Expression Profile and Its Association with Human Disorders with Special Focus on SARS-CoV-2 Infection Vascular Pharmacology. 07, 2020 | Pubmed ID: 32423553 Berberine Hampers Influenza A Replication Through Inhibition of MAPK/ERK Pathway Viruses. 03, 2020 | Pubmed ID: 32245183 MASS SPECTROMETRY IN VIROLOGICAL SCIENCES Mass Spectrometry Reviews. Sep, 2020 | Pubmed ID: 31876329 Cat Flu: Broad Spectrum Polymeric Antivirals Antiviral Research. 10, 2019 | Pubmed ID: 31325462 Membrane Protein of Human Coronavirus NL63 Is Responsible for Interaction with the Adhesion Receptor Journal of Virology. 10, 2019 | Pubmed ID: 31315999 Highly Effective and Safe Polymeric Inhibitors of Herpes Simplex Virus in Vitro and in Vivo ACS Applied Materials & Interfaces. Jul, 2019 | Pubmed ID: 31287654 Detection of Legal Highs in the Urine of Methadone-treated Patient by LC-MS Basic & Clinical Pharmacology & Toxicology. Sep, 2019 | Pubmed ID: 31188528 Zika Virus: Mapping and Reprogramming the Entry Cell Communication and Signaling : CCS. 05, 2019 | Pubmed ID: 31053158 Canine Respiratory Coronavirus, Bovine Coronavirus, and Human Coronavirus OC43: Receptors and Attachment Factors Viruses. 04, 2019 | Pubmed ID: 30959796 Synthetic Sulfonated Derivatives of Poly(allylamine Hydrochloride) As Inhibitors of Human Metapneumovirus PloS One. 2019 | Pubmed ID: 30921418 Phosphonate Inhibitors of West Nile Virus NS2B/NS3 Protease Journal of Enzyme Inhibition and Medicinal Chemistry. Dec, 2019 | Pubmed ID: 30362835 One Step Beyond: Design of Substrates Spanning Primed Positions of Zika Virus NS2B-NS3 Protease ACS Medicinal Chemistry Letters. Oct, 2018 | Pubmed ID: 30344911 Novel Coronavirus-like Particles Targeting Cells Lining the Respiratory Tract PloS One. 2018 | Pubmed ID: 30183777 Canine Respiratory Coronavirus Employs Caveolin-1-mediated Pathway for Internalization to HRT-18G Cells Veterinary Research. 07, 2018 | Pubmed ID: 29970183 Early Events During Human Coronavirus OC43 Entry to the Cell Scientific Reports. 05, 2018 | Pubmed ID: 29740099 APOBEC3-mediated Restriction of RNA Virus Replication Scientific Reports. 04, 2018 | Pubmed ID: 29654310 Entry of Human Coronavirus NL63 into the Cell Journal of Virology. 02, 2018 | Pubmed ID: 29142129 Small-molecule Inhibitors of PD-1/PD-L1 Immune Checkpoint Alleviate the PD-L1-induced Exhaustion of T-cells Oncotarget. Sep, 2017 | Pubmed ID: 29069777 Inhibition of Herpes Simplex Viruses by Cationic Dextran Derivatives Journal of Medicinal Chemistry. 10, 2017 | Pubmed ID: 28956914 Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR) RNAs in the Porphyromonas Gingivalis CRISPR-Cas I-C System Journal of Bacteriology. 12, 2017 | Pubmed ID: 28893837 Novel Peptidyl α-aminoalkylphosphonates As Inhibitors of Hepatitis C Virus NS3/4A Protease Antiviral Research. 08, 2017 | Pubmed ID: 28673801 Broad-spectrum Antiviral GS-5734 Inhibits Both Epidemic and Zoonotic Coronaviruses Science Translational Medicine. 06, 2017 | Pubmed ID: 28659436 Biopolymeric Nano/microspheres for Selective and Reversible Adsorption of Coronaviruses Materials Science & Engineering. C, Materials for Biological Applications. Jul, 2017 | Pubmed ID: 28482585 Structural Characterization of Human Coronavirus NL63 N Protein Journal of Virology. 06, 2017 | Pubmed ID: 28331093 Substrate Profiling of Zika Virus NS2B-NS3 Protease FEBS Letters. Oct, 2016 | Pubmed ID: 27714789 Type III CRISPR Complexes from Thermus Thermophilus Acta Biochimica Polonica. 2016 | Pubmed ID: 27299480 HTCC: Broad Range Inhibitor of Coronavirus Entry PloS One. 2016 | Pubmed ID: 27249425 Novel Polyanions Inhibiting Replication of Influenza Viruses Antimicrobial Agents and Chemotherapy. Apr, 2016 | Pubmed ID: 26729490 Gingipains: Critical Factors in the Development of Aspiration Pneumonia Caused by Porphyromonas Gingivalis Journal of Innate Immunity. 2016 | Pubmed ID: 26613585 Functional Analysis of Porphyromonas Gingivalis W83 CRISPR-Cas Systems Journal of Bacteriology. Aug, 2015 | Pubmed ID: 26013482 Human Coronavirus HKU1 Spike Protein Uses O-Acetylated Sialic Acid As an Attachment Receptor Determinant and Employs Hemagglutinin-Esterase Protein As a Receptor-Destroying Enzyme Journal of Virology. Jul, 2015 | Pubmed ID: 25926653 The Inhibitory Effect of Secretory Leukocyte Protease Inhibitor (SLPI) on Formation of Neutrophil Extracellular Traps Journal of Leukocyte Biology. Jul, 2015 | Pubmed ID: 25917460 The Nucleocapsid Protein of Human Coronavirus NL63 PloS One. 2015 | Pubmed ID: 25700263 Human Coronavirus NL63 Utilizes Heparan Sulfate Proteoglycans for Attachment to Target Cells Journal of Virology. Nov, 2014 | Pubmed ID: 25187545 Citrullination Alters Immunomodulatory Function of LL-37 Essential for Prevention of Endotoxin-induced Sepsis Journal of Immunology (Baltimore, Md. : 1950). Jun, 2014 | Pubmed ID: 24771854 Stability of Infectious Human Coronavirus NL63 Journal of Virological Methods. 09, 2014 | Pubmed ID: 24747590 Porphyromonas Gingivalis Facilitates the Development and Progression of Destructive Arthritis Through Its Unique Bacterial Peptidylarginine Deiminase (PAD) PLoS Pathogens. Sep, 2013 | Pubmed ID: 24068934 Staphylococcus Aureus Proteases Degrade Lung Surfactant Protein A Potentially Impairing Innate Immunity of the Lung Journal of Innate Immunity. 2013 | Pubmed ID: 23235402 HexaPrime: a Novel Method for Detection of Coronaviruses Journal of Virological Methods. Mar, 2013 | Pubmed ID: 23219933 Novel Polymeric Inhibitors of HCoV-NL63 Antiviral Research. Feb, 2013 | Pubmed ID: 23201315 Inactivation of Epidermal Growth Factor by Porphyromonas Gingivalis As a Potential Mechanism for Periodontal Tissue Damage Infection and Immunity. Jan, 2013 | Pubmed ID: 23090954 Bacterial Proteases in Disease - Role in Intracellular Survival, Evasion of Coagulation/ Fibrinolysis Innate Defenses, Toxicoses and Viral Infections Current Pharmaceutical Design. 2013 | Pubmed ID: 23016681 Replication-dependent Downregulation of Cellular Angiotensin-converting Enzyme 2 Protein Expression by Human Coronavirus NL63 The Journal of General Virology. Sep, 2012 | Pubmed ID: 22718567 Use of Sensitive, Broad-spectrum Molecular Assays and Human Airway Epithelium Cultures for Detection of Respiratory Pathogens PloS One. 2012 | Pubmed ID: 22403676 Porphyromonas Gingivalis Enzymes Enhance Infection with Human Metapneumovirus in Vitro The Journal of General Virology. Oct, 2011 | Pubmed ID: 21715599 Development of Loop-mediated Isothermal Amplification Assay for Detection of Human Coronavirus-NL63 Journal of Virological Methods. Jul, 2011 | Pubmed ID: 21545810 Infection with Human Coronavirus NL63 Enhances Streptococcal Adherence to Epithelial Cells The Journal of General Virology. Jun, 2011 | Pubmed ID: 21325482 Culturing the Unculturable: Human Coronavirus HKU1 Infects, Replicates, and Produces Progeny Virions in Human Ciliated Airway Epithelial Cell Cultures Journal of Virology. Nov, 2010 | Pubmed ID: 20719951 Human Coronavirus NL63 and 229E Seroconversion in Children Journal of Clinical Microbiology. Jul, 2008 | Pubmed ID: 18495857 Recent Antiviral Strategies Against Human Coronavirus-related Respiratory Illnesses Current Opinion in Pulmonary Medicine. May, 2008 | Pubmed ID: 18427249 SITUハイブリダイゼーションにおける免疫RNA-蛍光を用いたSARS-CoV-2の可視化 Anna Kula-Pacurar1, Jakub Wadas2, Agnieszka Suder1, Artur Szczepanski1,2, Aleksandra Milewska1,2, Marek Ochman3,4, Tomasz Stacel3,4, Krzysztof Pyrc1 1Malopolska Centre of Biotechnology, Jagiellonian University, 2Microbiology Department Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, 3Department of Cardiac, Vascular and Endovascular Surgery and Transplantology, The Medical University of Silesia in Katowice, 4Silesian Centre for Heart Diseases JoVE 62067 Immunology and Infection
SITUハイブリダイゼーションにおける免疫RNA-蛍光を用いたSARS-CoV-2の可視化 Anna Kula-Pacurar1, Jakub Wadas2, Agnieszka Suder1, Artur Szczepanski1,2, Aleksandra Milewska1,2, Marek Ochman3,4, Tomasz Stacel3,4, Krzysztof Pyrc1 1Malopolska Centre of Biotechnology, Jagiellonian University, 2Microbiology Department Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, 3Department of Cardiac, Vascular and Endovascular Surgery and Transplantology, The Medical University of Silesia in Katowice, 4Silesian Centre for Heart Diseases JoVE 62067 Immunology and Infection