Lee Ann Applegate Unit of Regenerative Therapy, Plastic, Reconstructive and Hand Surgery, Department of Musculoskeletal Medicine Lausanne University Hospital Biography Publications Institution JoVE Articles Lee Ann Applegate has not added a biography. If you are Lee Ann Applegate and would like to personalize this page please email our Author Liaison for assistance. Publications Retrospectives on Three Decades of Safe Clinical Experience with Allogeneic Dermal Progenitor Fibroblasts: High Versatility in Topical Cytotherapeutic Care Pharmaceutics. Jan, 2023 | Pubmed ID: 36678813 Lyophilized Progenitor Tenocyte Extracts: Sterilizable Cytotherapeutic Derivatives with Antioxidant Properties and Hyaluronan Hydrogel Functionalization Effects Antioxidants (Basel, Switzerland). Jan, 2023 | Pubmed ID: 36671025 Filamented Light (FLight) Biofabrication of Highly Aligned Tissue-Engineered Constructs Advanced Materials (Deerfield Beach, Fla.). Nov, 2022 | Pubmed ID: 36095325 Retrospective Analysis of Autologous Chondrocyte-Based Cytotherapy Production for Clinical Use: GMP Process-Based Manufacturing Optimization in a Swiss University Hospital Cells. Mar, 2022 | Pubmed ID: 35326468 Synergistic Effects of Antimicrobial Peptide Dendrimer-chitosan Polymer Conjugates Against Pseudomonas Aeruginosa Carbohydrate Polymers. Mar, 2022 | Pubmed ID: 35027127 Exudative Glutamine Losses Contribute to High Needs After Burn Injury JPEN. Journal of Parenteral and Enteral Nutrition. May, 2022 | Pubmed ID: 34288001 Combination of Hyaluronan and Lyophilized Progenitor Cell Derivatives: Stabilization of Functional Hydrogel Products for Therapeutic Management of Tendinous Tissue Disorders Pharmaceutics. Dec, 2021 | Pubmed ID: 34959477 Back to the Cradle of Cytotherapy: Integrating a Century of Clinical Research and Biotechnology-Based Manufacturing for Modern Tissue-Specific Cellular Treatments in Switzerland Bioengineering (Basel, Switzerland). Dec, 2021 | Pubmed ID: 34940374 Hypoxic Incubation Conditions for Optimized Manufacture of Tenocyte-Based Active Pharmaceutical Ingredients of Homologous Standardized Transplant Products in Tendon Regenerative Medicine Cells. Oct, 2021 | Pubmed ID: 34831095 Evolution of Diploid Progenitor Lung Cell Applications: From Optimized Biotechnological Substrates to Potential Active Pharmaceutical Ingredients in Respiratory Tract Regenerative Medicine Cells. Sep, 2021 | Pubmed ID: 34685505 Optimized Manufacture of Lyophilized Dermal Fibroblasts for Next-Generation Off-the-Shelf Progenitor Biological Bandages in Topical Post-Burn Regenerative Medicine Biomedicines. Aug, 2021 | Pubmed ID: 34440276 Corrigendum To: Burn Center Organization and Cellular Therapy Integration: Managing Risks and Costs Journal of Burn Care & Research : Official Publication of the American Burn Association. Sep, 2021 | Pubmed ID: 34337651 Human Platelet Lysate As an Alternative to Autologous Serum for Human Chondrocyte Clinical Use Cartilage. Dec, 2021 | Pubmed ID: 34330164 Antimicrobial Peptide Dendrimers and Quorum-Sensing Inhibitors in Formulating Next-Generation Anti-Infection Cell Therapy Dressings for Burns Molecules (Basel, Switzerland). Jun, 2021 | Pubmed ID: 34202446 Burn Center Organization and Cellular Therapy Integration: Managing Risks and Costs Journal of Burn Care & Research : Official Publication of the American Burn Association. Sep, 2021 | Pubmed ID: 33970273 Industrial Development of Standardized Fetal Progenitor Cell Therapy for Tendon Regenerative Medicine: Preliminary Safety in Xenogeneic Transplantation Biomedicines. Apr, 2021 | Pubmed ID: 33916829 Retrospective Evaluation of Progenitor Biological Bandage Use: A Complementary and Safe Therapeutic Management Option for Prevention of Hypertrophic Scarring in Pediatric Burn Care Pharmaceuticals (Basel, Switzerland). Feb, 2021 | Pubmed ID: 33671009 Development of Standardized Fetal Progenitor Cell Therapy for Cartilage Regenerative Medicine: Industrial Transposition and Preliminary Safety in Xenogeneic Transplantation Biomolecules. Feb, 2021 | Pubmed ID: 33572428 Progenitor Biological Bandages: An Authentic Swiss Tool for Safe Therapeutic Management of Burns, Ulcers, and Donor Site Grafts Methods in Molecular Biology (Clifton, N.J.). 2021 | Pubmed ID: 32572700 GMP Tiered Cell Banking of Non-enzymatically Isolated Dermal Progenitor Fibroblasts for Allogenic Regenerative Medicine Methods in Molecular Biology (Clifton, N.J.). 2021 | Pubmed ID: 32468492 Swiss Fetal Transplantation Program and Non-enzymatically Isolated Primary Progenitor Cell Types for Regenerative Medicine Methods in Molecular Biology (Clifton, N.J.). 2021 | Pubmed ID: 32430595 Holistic Approach of Swiss Fetal Progenitor Cell Banking: Optimizing Safe and Sustainable Substrates for Regenerative Medicine and Biotechnology Frontiers in Bioengineering and Biotechnology. 2020 | Pubmed ID: 33195124 Surgical Management Evolution Between 2 Massive Burn Cases at 17-Year Interval: Contribution of Cell Therapies in Improving the Surgical Care Cell Transplantation. 2020 | Pubmed ID: 33172295 Bringing Safe and Standardized Cell Therapies to Industrialized Processing for Burns and Wounds Frontiers in Bioengineering and Biotechnology. 2020 | Pubmed ID: 32637400 Reply to the Letter to the Editor on "The Use of Antiseptics in Burn Wounds - Our Perspective" Burns : Journal of the International Society for Burn Injuries. Jun, 2020 | Pubmed ID: 32387097 Implications of Chlorhexidine Use in Burn Units for Wound Healing Burns : Journal of the International Society for Burn Injuries. Aug, 2020 | Pubmed ID: 31911075 Efficient Decellularization of Equine Tendon with Preserved Biomechanical Properties and Cytocompatibility for Human Tendon Surgery Indications Artificial Organs. Apr, 2020 | Pubmed ID: 31609006 Evolution of Biological Bandages As First Cover for Burn Patients Advances in Wound Care. Nov, 2019 | Pubmed ID: 31637102 An Injectable Heparin-conjugated Hyaluronan Scaffold for Local Delivery of Transforming Growth Factor β1 Promotes Successful Chondrogenesis Acta Biomaterialia. Nov, 2019 | Pubmed ID: 31536840 Expression and Activity of TRPA1 and TRPV1 in the Intervertebral Disc: Association with Inflammation and Matrix Remodeling International Journal of Molecular Sciences. Apr, 2019 | Pubmed ID: 30974795 Trace Element Intakes Should Be Revisited in Burn Nutrition Protocols: A Cohort Study Clinical Nutrition (Edinburgh, Scotland). Jun, 2018 | Pubmed ID: 28455105 Return of the Cadaver: Key Role of Anatomic Dissection for Plastic Surgery Resident Training Medicine. Jul, 2017 | Pubmed ID: 28723767 Association of Variants in SH2B1 and RABEP1 with Worsening of Low-density Lipoprotein and Glucose Parameters in Patients Treated with Psychotropic Drugs Gene. Sep, 2017 | Pubmed ID: 28694205 First Insights into Human Fingertip Regeneration by Echo-Doppler Imaging and Wound Microenvironment Assessment International Journal of Molecular Sciences. May, 2017 | Pubmed ID: 28505080 Topical Negative Pressure on Burns: An Innovative Method for Wound Exudate Collection Plastic and Reconstructive Surgery. Global Open. Nov, 2016 | Pubmed ID: 27975022 Effect of Human Burn Wound Exudate on Pseudomonas Aeruginosa Virulence MSphere. 2016 | Pubmed ID: 27303724 Sildenafil As a Therapeutic Option for Digital Ischemic Ulceration: Case Report The Journal of Hand Surgery. May, 2015 | Pubmed ID: 25817752 Insurance Coverage of Pediatric Burns: Switzerland Versus USA Burns : Journal of the International Society for Burn Injuries. Aug, 2014 | Pubmed ID: 24286612 Whole-cell Bioprocessing of Human Fetal Cells for Tissue Engineering of Skin Skin Pharmacology and Physiology. 2009 | Pubmed ID: 19188754 Wound-healing Gene Family Expression Differences Between Fetal and Foreskin Cells Used for Bioengineered Skin Substitutes Artificial Organs. Jul, 2008 | Pubmed ID: 18638304 ヒト異種異系フリーのヒト治療法によるヒト脂肪由来幹細胞の単離と培養 Martino Guiotto*1,4, Silvia Palombella*2, Stefania Brambilla2, Lee Ann Applegate3, Mathis Riehle4, Andrew Hart4, Wassim Raffoul1, Pietro Giovanni di Summa1 1Department of Plastic, Reconstructive and Hand Surgery, Centre Hospitalier Universitaire Vaudois (CHUV, 2Cell and Tissue Engineering Lab, IRCCS Ospedale Galeazzi Sant'Ambrogio, 3Unit of Regenerative Therapy, Plastic, Reconstructive and Hand Surgery, Department of Musculoskeletal Medicine, Lausanne University Hospital, 4Centre for the Cellular Microenvironment, University of Glasgow JoVE 65104 Medicine
ヒト異種異系フリーのヒト治療法によるヒト脂肪由来幹細胞の単離と培養 Martino Guiotto*1,4, Silvia Palombella*2, Stefania Brambilla2, Lee Ann Applegate3, Mathis Riehle4, Andrew Hart4, Wassim Raffoul1, Pietro Giovanni di Summa1 1Department of Plastic, Reconstructive and Hand Surgery, Centre Hospitalier Universitaire Vaudois (CHUV, 2Cell and Tissue Engineering Lab, IRCCS Ospedale Galeazzi Sant'Ambrogio, 3Unit of Regenerative Therapy, Plastic, Reconstructive and Hand Surgery, Department of Musculoskeletal Medicine, Lausanne University Hospital, 4Centre for the Cellular Microenvironment, University of Glasgow JoVE 65104 Medicine