Lee M. Nadler

Publications

• Ex Vivo Expansion of Human CD8 T Cells Using Autologous CD4 T Cell Help
  PloS One. 2012  |   Pubmed ID: 22279573
• IL-21 Can Supplement Suboptimal Lck-Independent MAPK Activation in a STAT-3-Dependent Manner in Human CD8+ T Cells
  Journal of Immunology (Baltimore, Md. : 1950). Feb, 2012  |   Pubmed ID: 22238455
• Induction of HLA-DP4-restricted Anti-survivin Th1 and Th2 Responses Using an Artificial Antigen-presenting Cell
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Aug, 2011  |   Pubmed ID: 21705450
• Aberrant Expression of Functional BAFF-system Receptors by Malignant B-cell Precursors Impacts Leukemia Cell Survival
  PloS One. 2011  |   Pubmed ID: 21687682
• Establishment of Antitumor Memory in Humans Using in Vitro-educated CD8+ T Cells
  Science Translational Medicine. Apr, 2011  |   Pubmed ID: 21525398
• Targeting of Active MTOR Inhibits Primary Leukemia T Cells and Synergizes with Cytotoxic Drugs and Signaling Inhibitors
  Experimental Hematology. Apr, 2011  |   Pubmed ID: 21277936
• A Phase III Study of Anti-B4-blocked Ricin As Adjuvant Therapy Post-autologous Bone Marrow Transplant: CALGB 9254
  Leukemia & Lymphoma. Apr, 2011  |   Pubmed ID: 21275630
• A Panel of Human Cell-based Artificial APC Enables the Expansion of Long-lived Antigen-specific CD4+ T Cells Restricted by Prevalent HLA-DR Alleles
  International Immunology. Nov, 2010  |   Pubmed ID: 21059769
• Combining CD19 Redirection and Alloanergization to Generate Tumor-specific Human T Cells for Allogeneic Cell Therapy of B-cell Malignancies
  Cancer Research. May, 2010  |   Pubmed ID: 20424114
• Expansion of Allospecific Regulatory T Cells After Anergized, Mismatched Bone Marrow Transplantation
  Science Translational Medicine. Oct, 2009  |   Pubmed ID: 20368155
• Cyclin D1-specific Cytotoxic T Lymphocytes Are Present in the Repertoire of Cancer Patients: Implications for Cancer Immunotherapy
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Oct, 2008  |   Pubmed ID: 18927298
• Dissociation of Its Opposing Immunologic Effects is Critical for the Optimization of Antitumor CD8+ T-cell Responses Induced by Interleukin 21
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Oct, 2008  |   Pubmed ID: 18829491
• Induction of Alloanergy in Human Donor T Cells Without Loss of Pathogen or Tumor Immunity
  Transplantation. Sep, 2008  |   Pubmed ID: 18813111
• CpG Oligodeoxynucleotides Alter Lymphocyte and Dendritic Cell Trafficking in Humans
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Sep, 2008  |   Pubmed ID: 18765557
• Identification of an Evolutionarily Conserved Transcriptional Signature of CD8 Memory Differentiation That is Shared by T and B Cells
  Journal of Immunology (Baltimore, Md. : 1950). Aug, 2008  |   Pubmed ID: 18641323
• Outcome of Alloanergized Haploidentical Bone Marrow Transplantation After Ex Vivo Costimulatory Blockade: Results of 2 Phase 1 Studies
  Blood. Sep, 2008  |   Pubmed ID: 18617635
• Lee Marshall Nadler, MD: a Conversation with the Editor
  Proceedings (Baylor University. Medical Center). Oct, 2007  |   Pubmed ID: 17948113
• Long-term Survival After Autologous Bone Marrow Transplantation for Follicular Lymphoma in First Remission
  Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation. Sep, 2007  |   Pubmed ID: 17697968
• Long-lived Antitumor CD8+ Lymphocytes for Adoptive Therapy Generated Using an Artificial Antigen-presenting Cell
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Mar, 2007  |   Pubmed ID: 17363542
• Identification of an Immunogenic CD8+ T-cell Epitope Derived from Gamma-globin, a Putative Tumor-associated Antigen for Juvenile Myelomonocytic Leukemia
  Blood. Oct, 2006  |   Pubmed ID: 16778141
• Efficient Presentation of Naturally Processed HLA Class I Peptides by Artificial Antigen-presenting Cells for the Generation of Effective Antitumor Responses
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. May, 2006  |   Pubmed ID: 16707591
• Leukemia-stimulated Bone Marrow Endothelium Promotes Leukemia Cell Survival
  Experimental Hematology. May, 2006  |   Pubmed ID: 16647567
• CD40-activated B Cells Express Full Lymph Node Homing Triad and Induce T-cell Chemotaxis: Potential As Cellular Adjuvants
  Blood. Apr, 2006  |   Pubmed ID: 16357329
• Engagement of CD83 Ligand Induces Prolonged Expansion of CD8+ T Cells and Preferential Enrichment for Antigen Specificity
  Blood. Feb, 2006  |   Pubmed ID: 16239433
• Proangiogenic Stimulation of Bone Marrow Endothelium Engages MTOR and is Inhibited by Simultaneous Blockade of MTOR and NF-kappaB
  Blood. Jan, 2006  |   Pubmed ID: 16141350
• Gene Expression Profiling Identifies BAX-delta As a Novel Tumor Antigen in Acute Lymphoblastic Leukemia
  Cancer Research. Nov, 2005  |   Pubmed ID: 16267031
• Autologous and Allogeneic Stem Cell Transplantations for Poor-risk Chronic Lymphocytic Leukemia
  Blood. Dec, 2005  |   Pubmed ID: 16131571
• Phase I/II Combined Chemoimmunotherapy with Carcinoembryonic Antigen-derived HLA-A2-restricted CAP-1 Peptide and Irinotecan, 5-fluorouracil, and Leucovorin in Patients with Primary Metastatic Colorectal Cancer
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Aug, 2005  |   Pubmed ID: 16115944
• Unexpected Association Between Induction of Immunity to the Universal Tumor Antigen CYP1B1 and Response to Next Therapy
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jun, 2005  |   Pubmed ID: 15958627
• Antigen-specific T-cell Memory is Preserved in Children Treated for Acute Lymphoblastic Leukemia
  Blood. Sep, 2005  |   Pubmed ID: 15920008
• Increasing Incidence of Late Second Malignancies After Conditioning with Cyclophosphamide and Total-body Irradiation and Autologous Bone Marrow Transplantation for Non-Hodgkin's Lymphoma
  Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Apr, 2005  |   Pubmed ID: 15753460
• Failure to Define Window of Time for Autologous Tumor Vaccination in Patients with Newly Diagnosed or Relapsed Acute Lymphoblastic Leukemia
  Experimental Hematology. Mar, 2005  |   Pubmed ID: 15730852
• Identification of a New HLA-A*0201-restricted Cryptic Epitope from CYP1B1
  International Journal of Cancer. Journal International Du Cancer. Jun, 2005  |   Pubmed ID: 15688394
• Presence of Anti-kinectin and Anti-PMS1 Antibodies in Japanese Aplastic Anaemia Patients
  British Journal of Haematology. Jan, 2005  |   Pubmed ID: 15638857
• Combination Immunotherapy with a CpG Oligonucleotide (1018 ISS) and Rituximab in Patients with Non-Hodgkin Lymphoma: Increased Interferon-alpha/beta-inducible Gene Expression, Without Significant Toxicity
  Blood. Jan, 2005  |   Pubmed ID: 15358617
• Common Gamma Chain-signaling Cytokines Promote Proliferation of T-cell Acute Lymphoblastic Leukemia
  Haematologica. Dec, 2004  |   Pubmed ID: 15590396
• Measuring T Cell Immunity to Influenza Vaccination in Children After Haemopoietic Stem Cell Transplantation
  British Journal of Haematology. Nov, 2004  |   Pubmed ID: 15491293
• Activation of PI3K is Indispensable for Interleukin 7-mediated Viability, Proliferation, Glucose Use, and Growth of T Cell Acute Lymphoblastic Leukemia Cells
  The Journal of Experimental Medicine. Sep, 2004  |   Pubmed ID: 15353558
• PH-triggered Microparticles for Peptide Vaccination
  Journal of Immunology (Baltimore, Md. : 1950). Aug, 2004  |   Pubmed ID: 15294974
• Correspondence Re R. Lapointe Et Al., CD40-stimulated B Lymphocytes Pulsed with Tumor Antigens Are Effective Antigen-presenting Cells That Can Generate Specific T Cells. Cancer Res 2003;63:2836-43
  Cancer Research. Jun, 2004  |   Pubmed ID: 15173021
• Autologous Bone Marrow Transplantation for Marginal Zone Non-Hodgkin's Lymphoma
  Leukemia & Lymphoma. Feb, 2004  |   Pubmed ID: 15101717
• Vaccination of Cancer Patients Against Telomerase Induces Functional Antitumor CD8+ T Lymphocytes
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Feb, 2004  |   Pubmed ID: 14871958
• IL-7-dependent Human Leukemia T-cell Line As a Valuable Tool for Drug Discovery in T-ALL
  Blood. Mar, 2004  |   Pubmed ID: 14615384
• Autoantibodies Frequently Detected in Patients with Aplastic Anemia
  Blood. Dec, 2003  |   Pubmed ID: 12947009
• Differential Localization and Function of ADP-ribosylation Factor-6 in Anergic Human T Cells: a Potential Marker for Their Identification
  Journal of Immunology (Baltimore, Md. : 1950). Aug, 2003  |   Pubmed ID: 12902467
• The Shared Tumor-associated Antigen Cytochrome P450 1B1 is Recognized by Specific Cytotoxic T Cells
  Blood. Nov, 2003  |   Pubmed ID: 12869499
• Viral Antigen-specific CD8+ T-cell Responses Are Impaired in Multiple Myeloma
  British Journal of Haematology. Jun, 2003  |   Pubmed ID: 12786794
• MUC1-like Tandem Repeat Proteins Are Broadly Immunogenic in Cancer Patients
  Cancer Immunity : a Journal of the Academy of Cancer Immunology. Mar, 2003  |   Pubmed ID: 12747745
• CAMP Inhibits Both Ras and Rap1 Activation in Primary Human T Lymphocytes, but Only Ras Inhibition Correlates with Blockade of Cell Cycle Progression
  Blood. Feb, 2003  |   Pubmed ID: 12393539
• From Genomics to Cancer Vaccines: Patient-tailored or Universal Vaccines?
  Current Opinion in Molecular Therapeutics. Dec, 2002  |   Pubmed ID: 12596359
• HER-2/neu and HTERT Cryptic Epitopes As Novel Targets for Broad Spectrum Tumor Immunotherapy
  Journal of Immunology (Baltimore, Md. : 1950). Jun, 2002  |   Pubmed ID: 12023395
• Human Primary and Memory Cytotoxic T Lymphocyte Responses Are Efficiently Induced by Means of CD40-activated B Cells As Antigen-presenting Cells: Potential for Clinical Application
  Blood. May, 2002  |   Pubmed ID: 11964299
• CD28 Costimulation Mediates Down-regulation of P27kip1 and Cell Cycle Progression by Activation of the PI3K/PKB Signaling Pathway in Primary Human T Cells
  Journal of Immunology (Baltimore, Md. : 1950). Mar, 2002  |   Pubmed ID: 11884439
• Blockade of B7/CD28 in Mixed Lymphocyte Reaction Cultures Results in the Generation of Alternatively Activated Macrophages, Which Suppress T-cell Responses
  Blood. Feb, 2002  |   Pubmed ID: 11830501