Liying Yan Center for Reproductive Medicine, Department of Obstetrics and Gynecology Peking University Third Hospital Biography Publications Institution JoVE Articles Liying Yan has not added a biography. If you are Liying Yan and would like to personalize this page please email our Author Liaison for assistance. Publications A Comprehensive PGT-M Strategy for ADPKD Patients with De Novo PKD1 Mutations Using Affected Embryo or Gametes As Proband Journal of Assisted Reproduction and Genetics. May, 2021 | Pubmed ID: 33939064 Age-related Changes in Human Conventional Semen Parameters and Sperm Chromatin Structure Assay-defined Sperm DNA/chromatin Integrity Reproductive Biomedicine Online. May, 2021 | Pubmed ID: 33785305 Poor Intracytoplasmic Sperm Injection Outcome in Infertile Males with Azoospermia Factor C Microdeletions Fertility and Sterility. Mar, 2021 | Pubmed ID: 33745721 Clinical Application of an NGS-based Method in the Preimplantation Genetic Testing for Duchenne Muscular Dystrophy Journal of Assisted Reproduction and Genetics. Mar, 2021 | Pubmed ID: 33719023 Single-cell Multiomics Sequencing Reveals the Functional Regulatory Landscape of Early Embryos Nature Communications. 02, 2021 | Pubmed ID: 33623021 The Methylome of a Human Polar Body Reflects That of Its Sibling Oocyte and Its Aberrance May Indicate Poor Embryo Development Human Reproduction (Oxford, England). Jan, 2021 | Pubmed ID: 33313772 Dissecting the Epigenomic Dynamics of Human Fetal Germ Cell Development at Single-cell Resolution Cell Research. Apr, 2021 | Pubmed ID: 32884136 Effects of Vitrification and Cryostorage Duration on Single-cell RNA-Seq Profiling of Vitrified-thawed Human Metaphase II Oocytes Frontiers of Medicine. Feb, 2021 | Pubmed ID: 32876878 Epigenetic Consequences of Hormonal Interactions Between Opposite-sex Twin Fetuses Clinical and Translational Medicine. Dec, 2020 | Pubmed ID: 33377650 Integrated Multi-omics Reveal Epigenomic Disturbance of Assisted Reproductive Technologies in Human Offspring EBioMedicine. Nov, 2020 | Pubmed ID: 33099088 SARS-CoV-2 Entry Factors: and Are Expressed in Peri-Implantation Embryos and the Maternal-Fetal Interface Engineering (Beijing, China). Oct, 2020 | Pubmed ID: 32837754 A Novel Pathogenic Mutation in FBN2 Associated with Congenital Contractural Arachnodactyly for Preimplantation Genetic Diagnosis Journal of Genetics and Genomics = Yi Chuan Xue Bao. 05, 2020 | Pubmed ID: 32747207 Effects of Oocyte Vitrification on the Behaviors and Physiological Indexes of Aged First Filial Generation Mice Cryobiology. 08, 2020 | Pubmed ID: 32598946 Effect of Serum 25-hydroxyvitamin D Levels on Sperm Quality and Assisted Reproductive Technology Outcomes for Men of Infertile Chinese Couples Andrology. 09, 2020 | Pubmed ID: 32412142 A Strategy Using SNP Linkage Analysis for Monogenic Diseases PGD Combined with HLA Typing Clinical Genetics. 08, 2020 | Pubmed ID: 32378203 Single-cell Transcriptome Analysis of the Novel Coronavirus (SARS-CoV-2) Associated Gene ACE2 Expression in Normal and Non-obstructive Azoospermia (NOA) Human Male Testes Science China. Life Sciences. 07, 2020 | Pubmed ID: 32361911 Novel PGD Strategy Based on Single Sperm Linkage Analysis for Carriers of Single Gene Pathogenic Variant and Chromosome Reciprocal Translocation Journal of Assisted Reproduction and Genetics. May, 2020 | Pubmed ID: 32350783 Bioinspired L-Proline Oligomers for the Cryopreservation of Oocytes Controlling Ice Growth ACS Applied Materials & Interfaces. Apr, 2020 | Pubmed ID: 32227894 A Novel Homozygous Mutation of Phospholipase C Zeta Leading to Defective Human Oocyte Activation and Fertilization Failure Human Reproduction (Oxford, England). 04, 2020 | Pubmed ID: 32142120 ScHaplotyper: Haplotype Construction and Visualization for Genetic Diagnosis Using Single Cell DNA Sequencing Data BMC Bioinformatics. Feb, 2020 | Pubmed ID: 32007105 Trio-whole-exome Sequencing and Preimplantation Genetic Diagnosis for Unexplained Recurrent Fetal Malformations Human Mutation. 02, 2020 | Pubmed ID: 31680349 Genetic Analysis and Preimplantation Genetic Diagnosis of Chinese Marfan Syndrome Patients Journal of Genetics and Genomics = Yi Chuan Xue Bao. 06, 2019 | Pubmed ID: 31279624 Genetic Testing and PGD for Unexplained Recurrent Fetal Malformations with MAGEL2 Gene Mutation Science China. Life Sciences. Jul, 2019 | Pubmed ID: 31152388 Epigenetic Regulation and Risk Factors During the Development of Human Gametes and Early Embryos Annual Review of Genomics and Human Genetics. 08, 2019 | Pubmed ID: 30917080 Risk of Miscarriage in Women with Endometriosis Undergoing IVF Fresh Cycles: a Retrospective Cohort Study Reproductive Biology and Endocrinology : RB&E. Feb, 2019 | Pubmed ID: 30755216 Endometrial MiR-543 Is Downregulated During the Implantation Window in Women With Endometriosis-Related Infertility Reproductive Sciences (Thousand Oaks, Calif.). 07, 2019 | Pubmed ID: 30231774 Single-cell Multiomics Sequencing and Analyses of Human Colorectal Cancer Science (New York, N.Y.). 11, 2018 | Pubmed ID: 30498128 Transcriptome Landscape of Human Folliculogenesis Reveals Oocyte and Granulosa Cell Interactions Molecular Cell. 12, 2018 | Pubmed ID: 30472193 The Present and Future of Whole-exome Sequencing in Studying and Treating Human Reproductive Disorders Journal of Genetics and Genomics = Yi Chuan Xue Bao. 10, 2018 | Pubmed ID: 30391409 Identifying Normal Embryos from Reciprocal Translocation Carriers by Whole Chromosome Haplotyping Journal of Genetics and Genomics = Yi Chuan Xue Bao. 09, 2018 | Pubmed ID: 30287172 Publisher Correction: Tracing the Temporal-spatial Transcriptome Landscapes of the Human Fetal Digestive Tract Using Single-cell RNA-sequencing Nature Cell Biology. Oct, 2018 | Pubmed ID: 30038257 Transcriptome Analysis of PCOS Arrested 2-cell Embryos Cell Cycle (Georgetown, Tex.). 2018 | Pubmed ID: 29912628 Tracing the Temporal-spatial Transcriptome Landscapes of the Human Fetal Digestive Tract Using Single-cell RNA-sequencing Nature Cell Biology. 06, 2018 | Pubmed ID: 29802404 Activation of Hedgehog Signaling and Its Association with Cisplatin Resistance in Ovarian Epithelial Tumors Oncology Letters. Apr, 2018 | Pubmed ID: 29552194 Single-cell DNA Methylome Sequencing of Human Preimplantation Embryos Nature Genetics. 01, 2018 | Pubmed ID: 29255258 [Advance in the Methods of Preimplantation Genetic Diagnosis for Single Gene Diseases] Zhonghua Yi Xue Yi Chuan Xue Za Zhi = Zhonghua Yixue Yichuanxue Zazhi = Chinese Journal of Medical Genetics. Jun, 2017 | Pubmed ID: 28604975 Mesenchymal Stem Cell-derived Angiogenin Promotes Primodial Follicle Survival and Angiogenesis in Transplanted Human Ovarian Tissue Reproductive Biology and Endocrinology : RB&E. Mar, 2017 | Pubmed ID: 28274269 Testosterone Represses Estrogen Signaling by Upregulating MiR-22: A Mechanism for Imbalanced Steroid Hormone Production in Preeclampsia Hypertension (Dallas, Tex. : 1979). 04, 2017 | Pubmed ID: 28193709 Re-analysis of Aneuploidy Blastocysts with an Inner Cell Mass and Different Regional Trophectoderm Cells Journal of Assisted Reproduction and Genetics. Apr, 2017 | Pubmed ID: 28188593 Clinical Applications of MARSALA for Preimplantation Genetic Diagnosis of Spinal Muscular Atrophy Journal of Genetics and Genomics = Yi Chuan Xue Bao. 09, 2016 | Pubmed ID: 27599922 Fractalkine Restores the Decreased Expression of StAR and Progesterone in Granulosa Cells from Patients with Polycystic Ovary Syndrome Scientific Reports. 07, 2016 | Pubmed ID: 27386819 Validation of a Next-generation Sequencing-based Protocol for 24-chromosome Aneuploidy Screening of Blastocysts Fertility and Sterility. Jun, 2016 | Pubmed ID: 26902859 Human Single Follicle Growth in Vitro from Cryopreserved Ovarian Tissue After Slow Freezing or Vitrification Human Reproduction (Oxford, England). Apr, 2016 | Pubmed ID: 26851603 High-fat Diets Exaggerate Endocrine and Metabolic Phenotypes in a Rat Model of DHEA-induced PCOS Reproduction (Cambridge, England). Apr, 2016 | Pubmed ID: 26814210 Mesenchymal Stem Cells Facilitate In Vitro Development of Human Preantral Follicle Reproductive Sciences (Thousand Oaks, Calif.). Nov, 2015 | Pubmed ID: 25854744 Identification of a Human Subcortical Maternal Complex Molecular Human Reproduction. Apr, 2015 | Pubmed ID: 25542835 Mesenchymal Stem Cells Enhance Angiogenesis and Follicle Survival in Human Cryopreserved Ovarian Cortex Transplantation Cell Transplantation. 2015 | Pubmed ID: 25353724 Effect of Vitrification at the Germinal Vesicle Stage on the Global Methylation Status in Mouse Oocytes Subsequently Matured in Vitro Chinese Medical Journal. 2014 | Pubmed ID: 25430442 Validation of Multiple Annealing and Looping-based Amplification Cycle Sequencing for 24-chromosome Aneuploidy Screening of Cleavage-stage Embryos Fertility and Sterility. Dec, 2014 | Pubmed ID: 25241375 The DNA Methylation Landscape of Human Early Embryos Nature. Jul, 2014 | Pubmed ID: 25079557 Advances in Preimplantation Genetic Diagnosis/screening Science China. Life Sciences. Jul, 2014 | Pubmed ID: 24907939 Whole-genome Analysis of 5-hydroxymethylcytosine and 5-methylcytosine at Base Resolution in the Human Brain Genome Biology. 2014 | Pubmed ID: 24594098 Excessive Intrauterine Fluid Cause Aberrant Implantation and Pregnancy Outcome in Mice PloS One. 2013 | Pubmed ID: 24194934 Successful Reprogramming of Differentiated Cells by Somatic Cell Nuclear Transfer, Using in Vitro-matured Oocytes with a Modified Activation Method Journal of Tissue Engineering and Regenerative Medicine. Nov, 2013 | Pubmed ID: 22589148 Prenatal Diagnosis and Postnatal Followup of Partial Trisomy 13q and Partial Monosomy 10p: a Case Report and Review of the Literature Case Reports in Genetics. 2012 | Pubmed ID: 23133763 Effects of Combined Epidermal Growth Factor, Brain-derived Neurotrophic Factor and Insulin-like Growth Factor-1 on Human Oocyte Maturation and Early Fertilized and Cloned Embryo Development Human Reproduction (Oxford, England). Jul, 2012 | Pubmed ID: 22532606 In Vitro Maturation of Cumulus-partially Enclosed Immature Human Oocytes by Priming with Gonadotropin Fertility and Sterility. Sep, 2011 | Pubmed ID: 21762899 Association of TRB3 Q84R Polymorphism with Polycystic Ovary Syndrome in Chinese Women Reproductive Biology and Endocrinology : RB&E. Apr, 2011 | Pubmed ID: 21492415 OP-IVM: Combining In vitro Maturation after Oocyte Retrieval with Gynecological Surgery Tao Liu*1,2,3,4,5, Xueling Song*1,2,3,4,5, Xiaoying Zheng*1,2,3,4,5, Liying Yan1,2,3,4,5, Caihong Ma1,2,3,5, Rong Li1,2,3,4,5, Jie Yan1,2,3,4,5, Jie Qiao1,2,3,4,5 1Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, 2National Clinical Research Center for Obstetrics and Gynecology, 3Key Laboratory of Assisted Reproduction, Ministry of Education, 4Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproduction, 5Research Units of Comprehensive Diagnosis and Treatment of Oocyte Maturation Arrest, Chinese Academy of Medical Sciences JoVE 61647 Medicine
OP-IVM: Combining In vitro Maturation after Oocyte Retrieval with Gynecological Surgery Tao Liu*1,2,3,4,5, Xueling Song*1,2,3,4,5, Xiaoying Zheng*1,2,3,4,5, Liying Yan1,2,3,4,5, Caihong Ma1,2,3,5, Rong Li1,2,3,4,5, Jie Yan1,2,3,4,5, Jie Qiao1,2,3,4,5 1Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, 2National Clinical Research Center for Obstetrics and Gynecology, 3Key Laboratory of Assisted Reproduction, Ministry of Education, 4Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproduction, 5Research Units of Comprehensive Diagnosis and Treatment of Oocyte Maturation Arrest, Chinese Academy of Medical Sciences JoVE 61647 Medicine
