Lucilia Saraiva LAQV/REQUIMTE, Laboratory of Microbiology, Faculty of Pharmacy University of Porto Biography Publications Institution JoVE Articles Lucilia Saraiva has not added a biography. If you are Lucilia Saraiva and would like to personalize this page please email our Author Liaison for assistance. Publications Synthesis, Biological Evaluation, and In Silico Studies of Novel Aminated Xanthones As Potential P53-Activating Agents Molecules (Basel, Switzerland). May, 2019 | Pubmed ID: 31121972 Comparison Study of Different Extracts of , and the Rare (Lamiaceae): Chemical Characterization, Antioxidant, Antimicrobial and Cytotoxic Activities Biomolecules. May, 2019 | Pubmed ID: 31072074 New Inhibitor of the TAp73 Interaction with MDM2 and Mutant P53 with Promising Antitumor Activity Against Neuroblastoma Cancer Letters. Apr, 2019 | Pubmed ID: 30664963 New Alkoxy Flavone Derivatives Targeting Caspases: Synthesis and Antitumor Activity Evaluation Molecules (Basel, Switzerland). Dec, 2018 | Pubmed ID: 30602686 Improving Anticancer Activity Towards Colon Cancer Cells with a New P53-activating Agent British Journal of Pharmacology. 10, 2018 | Pubmed ID: 30076608 Targeting the MDM2-p53 Protein-protein Interaction with Prenylchalcones: Synthesis of a Small Library and Evaluation of Potential Antitumor Activity European Journal of Medicinal Chemistry. Aug, 2018 | Pubmed ID: 30041135 The Crystal Structure of the R280K Mutant of Human P53 Explains the Loss of DNA Binding International Journal of Molecular Sciences. Apr, 2018 | Pubmed ID: 29652801 P53 and Glucose Metabolism: an Orchestra to Be Directed in Cancer Therapy Pharmacological Research. 05, 2018 | Pubmed ID: 29580896 Discovery of a Small-molecule Protein Kinase Cδ-selective Activator with Promising Application in Colon Cancer Therapy Cell Death & Disease. 01, 2018 | Pubmed ID: 29348560 Medicinal Chemistry Strategies to Disrupt the P53-MDM2/MDMX Interaction Medicinal Research Reviews. 09, 2016 | Pubmed ID: 27302609 P53 Family Interactions and Yeast: Together in Anticancer Therapy Drug Discovery Today. Apr, 2016 | Pubmed ID: 26891980 Enhanced Cytotoxicity of Prenylated Chalcone Against Tumour Cells Via Disruption of the P53-MDM2 Interaction Life Sciences. Dec, 2015 | Pubmed ID: 26475964 Chronological Aging in Conidia of Pathogenic Aspergillus: Comparison Between Species Journal of Microbiological Methods. Nov, 2015 | Pubmed ID: 26341609 A Tryptophanol-derived Oxazolopiperidone Lactam is Cytotoxic Against Tumors Via Inhibition of P53 Interaction with Murine Double Minute Proteins Pharmacological Research. May-Jun, 2015 | Pubmed ID: 25814188 A Yeast Model of the Parkinson's Disease-associated Protein Parkin Experimental Cell Research. Apr, 2015 | Pubmed ID: 25728007 Oxazoloisoindolinones with in Vitro Antitumor Activity Selectively Activate a P53-pathway Through Potential Inhibition of the P53-MDM2 Interaction European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences. Jan, 2015 | Pubmed ID: 25312347 Studying P53 Family Proteins in Yeast: Induction of Autophagic Cell Death and Modulation by Interactors and Small Molecules Experimental Cell Research. Jan, 2015 | Pubmed ID: 25265062 Microglia P2Y₆ Receptors Mediate Nitric Oxide Release and Astrocyte Apoptosis Journal of Neuroinflammation. Sep, 2014 | Pubmed ID: 25178395 LRRK2, but Not Pathogenic Mutants, Protects Against H2O2 Stress Depending on Mitochondrial Function and Endocytosis in a Yeast Model Biochimica Et Biophysica Acta. Jun, 2014 | Pubmed ID: 24576675 Potential Small-molecule Activators of Caspase-7 Identified Using Yeast-based Caspase-3 and -7 Screening Assays European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences. Apr, 2014 | Pubmed ID: 24398107 SNaPaer: a Practical Single Nucleotide Polymorphism Multiplex Assay for Genotyping of Pseudomonas Aeruginosa PloS One. 2013 | Pubmed ID: 23776608 Interference of Aging Media on the Assessment of Yeast Chronological Life Span by Propidium Iodide Staining Folia Microbiologica. Jan, 2013 | Pubmed ID: 22828896 Contribution of Yeast Models to Neurodegeneration Research Journal of Biomedicine & Biotechnology. 2012 | Pubmed ID: 22910375 Contribution of Yeast and Plant Research for Improving Human Health Journal of Biomedicine & Biotechnology. 2012 | Pubmed ID: 22851885 Endocytosis Inhibition During H2O2-induced Apoptosis in Yeast FEMS Yeast Research. Nov, 2012 | Pubmed ID: 22741558 New Therapeutic Strategies for Cancer and Neurodegeneration Emerging from Yeast Cell-based Systems Current Pharmaceutical Design. 2012 | Pubmed ID: 22650181 New Insights into Cancer-related Proteins Provided by the Yeast Model The FEBS Journal. Mar, 2012 | Pubmed ID: 22239976 Yeast As a Chassis for Developing Functional Assays to Study Human P53 Paola Monti1, Bartolomeo Bosco2, Sara Gomes3, Lucilia Saraiva*3, Gilberto Fronza*1, Alberto Inga*2 1Mutagenesis and Cancer Prevention Unit, Ospedale Policlinico San Martino, 2Department CIBIO, University of Trento, 3LAQV/REQUIMTE, Laboratory of Microbiology, Faculty of Pharmacy, University of Porto JoVE 59071 Cancer Research
Yeast As a Chassis for Developing Functional Assays to Study Human P53 Paola Monti1, Bartolomeo Bosco2, Sara Gomes3, Lucilia Saraiva*3, Gilberto Fronza*1, Alberto Inga*2 1Mutagenesis and Cancer Prevention Unit, Ospedale Policlinico San Martino, 2Department CIBIO, University of Trento, 3LAQV/REQUIMTE, Laboratory of Microbiology, Faculty of Pharmacy, University of Porto JoVE 59071 Cancer Research