M. Lienhard Schmitz Institute of Biochemistry, Medical Faculty, Friedrichstrasse 24, Member of the German Center for Lung Research Justus-Liebig-University Biography Publications Institution JoVE Articles M. Lienhard Schmitz has not added a biography. If you are M. Lienhard Schmitz and would like to personalize this page please email our Author Liaison for assistance. Publications The Direct and Indirect Roles of NF-κB in Cancer: Lessons from Oncogenic Fusion Proteins and Knock-in Mice Biomedicines. Mar, 2018 | Pubmed ID: 29562713 NF-κB P65 Serine 467 Phosphorylation Sensitizes Mice to Weight Gain and TNFα-or Diet-induced Inflammation Biochimica Et Biophysica Acta. 10, 2017 | Pubmed ID: 28723419 The CCR4-NOT Complex Contributes to Repression of Major Histocompatibility Complex Class II Transcription Scientific Reports. Jun, 2017 | Pubmed ID: 28615693 The NF-κB-dependent and -independent Transcriptome and Chromatin Landscapes of Human Coronavirus 229E-infected Cells PLoS Pathogens. Mar, 2017 | Pubmed ID: 28355270 Testing the Effects of SIAH Ubiquitin E3 Ligases on Lysine Acetyl Transferases Methods in Molecular Biology (Clifton, N.J.). 2017 | Pubmed ID: 27761830 The Influenza A Virus Genotype Determines the Antiviral Function of NF-κB Journal of Virology. 09, 2016 | Pubmed ID: 27356900 K63-Ubiquitylation and TRAF6 Pathways Regulate Mammalian P-Body Formation and MRNA Decapping Molecular Cell. 06, 2016 | Pubmed ID: 27315556 SUMO5, a Novel Poly-SUMO Isoform, Regulates PML Nuclear Bodies Scientific Reports. 05, 2016 | Pubmed ID: 27211601 HIPK Family Kinases Bind and Regulate the Function of the CCR4-NOT Complex Molecular Biology of the Cell. 06, 2016 | Pubmed ID: 27122605 Cyclin-Dependent Kinases As Coregulators of Inflammatory Gene Expression Trends in Pharmacological Sciences. Feb, 2016 | Pubmed ID: 26719217 The Activation of IL-1-Induced Enhancers Depends on TAK1 Kinase Activity and NF-κB P65 Cell Reports. Feb, 2015 | Pubmed ID: 25660023 SUMO Modification of TBK1 at the Adaptor-binding C-terminal Coiled-coil Domain Contributes to Its Antiviral Activity Biochimica Et Biophysica Acta. Jan, 2015 | Pubmed ID: 25409927 The Intricate Interplay Between RNA Viruses and NF-κB Biochimica Et Biophysica Acta. Nov, 2014 | Pubmed ID: 25116307 Expression Pattern of Protease Activated Receptors in Lymphoid Cells Cellular Immunology. Mar-Apr, 2014 | Pubmed ID: 24637088 Cyclin-dependent Kinase 6 is a Chromatin-bound Cofactor for NF-κB-dependent Gene Expression Molecular Cell. Jan, 2014 | Pubmed ID: 24389100 The Cytokine-induced Conformational Switch of Nuclear Factor κB P65 is Mediated by P65 Phosphorylation The Biochemical Journal. Feb, 2014 | Pubmed ID: 24175631 Hsc70 is a Novel Interactor of NF-kappaB P65 in Living Hippocampal Neurons PloS One. 2013 | Pubmed ID: 23762333 Homeodomain-interacting Protein Kinase 2-dependent Repression of Myogenic Differentiation is Relieved by Its Caspase-mediated Cleavage Nucleic Acids Research. Jun, 2013 | Pubmed ID: 23620283 Posttranslational Modifications Regulate HIPK2, a Driver of Proliferative Diseases Journal of Molecular Medicine (Berlin, Germany). Sep, 2013 | Pubmed ID: 23616089 HIPK2 Kinase Activity Depends on Cis-autophosphorylation of Its Activation Loop Journal of Molecular Cell Biology. Feb, 2013 | Pubmed ID: 23000554 Cyclin-dependent Kinase 6 Phosphorylates NF-κB P65 at Serine 536 and Contributes to the Regulation of Inflammatory Gene Expression PloS One. 2012 | Pubmed ID: 23300567 Regulation of the Tumor Suppressor PML by Sequential Post-translational Modifications Frontiers in Oncology. 2012 | Pubmed ID: 23293771 The Coactivator Role of Histone Deacetylase 3 in IL-1-signaling Involves Deacetylation of P65 NF-κB Nucleic Acids Research. Oct, 2012 | Pubmed ID: 23087373 SIAH-mediated Ubiquitination and Degradation of Acetyl-transferases Regulate the P53 Response and Protein Acetylation Biochimica Et Biophysica Acta. Dec, 2012 | Pubmed ID: 23044042 A Redox-regulated SUMO/acetylation Switch of HIPK2 Controls the Survival Threshold to Oxidative Stress Molecular Cell. May, 2012 | Pubmed ID: 22503103 Regulation of NF-κB Activity by Competition Between RelA Acetylation and Ubiquitination Oncogene. Feb, 2012 | Pubmed ID: 21706061 Signal Integration, Crosstalk Mechanisms and Networks in the Function of Inflammatory Cytokines Biochimica Et Biophysica Acta. Dec, 2011 | Pubmed ID: 21787809 Control of Nuclear HIPK2 Localization and Function by a SUMO Interaction Motif Biochimica Et Biophysica Acta. Feb, 2011 | Pubmed ID: 21145359 Specification of the NF-kappaB Transcriptional Response by P65 Phosphorylation and TNF-induced Nuclear Translocation of IKK Epsilon Nucleic Acids Research. Oct, 2010 | Pubmed ID: 20507904 SUMOylation-dependent Localization of IKKepsilon in PML Nuclear Bodies is Essential for Protection Against DNA-damage-triggered Cell Death Molecular Cell. Feb, 2010 | Pubmed ID: 20188669 Activation of T Cells: Releasing the Brakes by Proteolytic Elimination of Cbl-b Science Signaling. Jun, 2009 | Pubmed ID: 19549983 Autoregulatory Feedback Loops Terminating the NF-kappaB Response Trends in Biochemical Sciences. Mar, 2009 | Pubmed ID: 19233657 An Inducible Autoregulatory Loop Between HIPK2 and Siah2 at the Apex of the Hypoxic Response Nature Cell Biology. Jan, 2009 | Pubmed ID: 19043406 Functional Architecture of the Cell Nucleus Biochimica Et Biophysica Acta. Nov, 2008 | Pubmed ID: 18929934 A Bacterial Small Molecule Undermining Immune Response Signaling Chembiochem : a European Journal of Chemical Biology. Nov, 2008 | Pubmed ID: 18823058 NIK and Cot Cooperate to Trigger NF-kappaB P65 Phosphorylation Biochemical and Biophysical Research Communications. Jun, 2008 | Pubmed ID: 18439422 NF-kappaB Inhibitors for the Treatment of Inflammatory Diseases and Cancer Current Medicinal Chemistry. 2007 | Pubmed ID: 17305539 HIPK2: a Versatile Switchboard Regulating the Transcription Machinery and Cell Death Cell Cycle (Georgetown, Tex.). Jan, 2007 | Pubmed ID: 17245128 Phosphorylation-dependent Control of Pc2 SUMO E3 Ligase Activity by Its Substrate Protein HIPK2 Molecular Cell. Oct, 2006 | Pubmed ID: 17018294 Roles of HIPK1 and HIPK2 in AML1- and P300-dependent Transcription, Hematopoiesis and Blood Vessel Formation The EMBO Journal. Sep, 2006 | Pubmed ID: 16917507 Autoregulatory Control of the P53 Response by Caspase-mediated Processing of HIPK2 The EMBO Journal. May, 2006 | Pubmed ID: 16601678 Controlling NF-kappaB Activation in T Cells by Costimulatory Receptors Cell Death and Differentiation. May, 2006 | Pubmed ID: 16410801 Formaldehyde-assisted Isolation of Regulatory Elements to Measure Chromatin Accessibility in Mammalian Cells Alfonso Rodríguez-Gil1, Tabea Riedlinger2, Olesja Ritter2, Vera V. Saul2, M. Lienhard Schmitz2 1Department of Oncohematology and Genetics. Institute of Biomedicine of Seville (IBiS), University Hospital Virgen del Rocío, 2Institute of Biochemistry, Medical Faculty, Friedrichstrasse 24, Member of the German Center for Lung Research, Justus-Liebig-University JoVE 57272 Genetics
Formaldehyde-assisted Isolation of Regulatory Elements to Measure Chromatin Accessibility in Mammalian Cells Alfonso Rodríguez-Gil1, Tabea Riedlinger2, Olesja Ritter2, Vera V. Saul2, M. Lienhard Schmitz2 1Department of Oncohematology and Genetics. Institute of Biomedicine of Seville (IBiS), University Hospital Virgen del Rocío, 2Institute of Biochemistry, Medical Faculty, Friedrichstrasse 24, Member of the German Center for Lung Research, Justus-Liebig-University JoVE 57272 Genetics
