Maarten van Dinther Oncode Institute and Department of Cell Chemical Biology Leiden University Medical Center Biography Publications Institution JoVE Articles Maarten van Dinther has not added a biography. If you are Maarten van Dinther and would like to personalize this page please email our Author Liaison for assistance. Publications VprBP Mitigates TGF-β and Activin Signaling by Promoting Smurf1-mediated Type I Receptor Degradation Journal of Molecular Cell Biology. 02, 2020 | Pubmed ID: 31291647 Role of Soluble Endoglin in BMP9 Signaling Proceedings of the National Academy of Sciences of the United States of America. 09, 2019 | Pubmed ID: 31431534 Autophagy Contributes to BMP Type 2 Receptor Degradation And development of Pulmonary Arterial Hypertension The Journal of Pathology. 11, 2019 | Pubmed ID: 31257577 USP4 Inhibits SMAD4 Monoubiquitination and Promotes Activin and BMP Signaling The EMBO Journal. 06, 2017 | Pubmed ID: 28468752 TMED10 Protein Interferes with Transforming Growth Factor (TGF)-β Signaling by Disrupting TGF-β Receptor Complex Formation The Journal of Biological Chemistry. Mar, 2017 | Pubmed ID: 28115518 Determining TGF-β Receptor Levels in the Cell Membrane Methods in Molecular Biology (Clifton, N.J.). 2016 | Pubmed ID: 26520116 Transforming Growth Factor β Signaling in Colorectal Cancer Cells With Microsatellite Instability Despite Biallelic Mutations in TGFBR2 Gastroenterology. Jun, 2015 | Pubmed ID: 25736321 Time-resolved Dissection of Early Phosphoproteome and Ensuing Proteome Changes in Response to TGF-β Science Signaling. Jul, 2014 | Pubmed ID: 25056879 ENDOGLIN is Dispensable for Vasculogenesis, but Required for Vascular Endothelial Growth Factor-induced Angiogenesis PloS One. 2014 | Pubmed ID: 24489709 Mutational Analysis of Sclerostin Shows Importance of the Flexible Loop and the Cystine-knot for Wnt-signaling Inhibition PloS One. 2013 | Pubmed ID: 24312339 Anti-Sclerostin Antibody Inhibits Internalization of Sclerostin and Sclerostin-mediated Antagonism of Wnt/LRP6 Signaling PloS One. 2013 | Pubmed ID: 23638027 LRP8 Mediates Wnt/β-catenin Signaling and Controls Osteoblast Differentiation Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Oct, 2012 | Pubmed ID: 22589174 ALK2-Mutation Bei Patienten Mit Down-Syndrom Und Eine Angeborene Herz Defekt European Journal of Human Genetics : EJHG. Apr, 2011 | Pubmed ID: 21248739 TGFbeta Aktiviert Mitogen - Und Stress-activated Protein Kinase-1 (MSK1) Zum Zelltod Zu Dämpfen The Journal of Biological Chemistry. Feb, 2011 | Pubmed ID: 21106525 Identifizierung Der Wichtigsten Rückstände Vermittlung Knochen Morphogenetic Proteins (BMP)-6 Widerstand Gegen Birne Hemmung Ermöglicht Veränderte BMPs Mit überlegener Agonist Tätigkeit The Journal of Biological Chemistry. Apr, 2010 | Pubmed ID: 20048150 ALK2-R206H-Mutation, Die Verbindung Mit Fibrodysplasia Ossificans Progressiva Verleiht Konstitutive Aktivität Der BMP Typ I Rezeptor Und Sensibilisiert Mesenchymale Zellen Induziert Durch BMP Osteoblasten Differenzierung Und Knochen-Bildung Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Jun, 2010 | Pubmed ID: 19929436 Autocrine Knochen Morphogenetische Protein-9 Signalisiert Durch Activin Rezeptor-wie Kinase-2/Smad1/Smad4 Ovarian Krebs Zellproliferation Zu Fördern Cancer Research. Dec, 2009 | Pubmed ID: 19996292 VEGF Und Inhibitoren Der TGFbeta Zu Geben-ich Rezeptor Kinase Fördern Synergistisch Blutgefäß Bildung Durch Induzieren Alpha5-Integrin-Ausdruck Journal of Cell Science. Sep, 2009 | Pubmed ID: 19706683 BMP-9 Signals Via ALK1 and Inhibits BFGF-induced Endothelial Cell Proliferation and VEGF-stimulated Angiogenesis Journal of Cell Science. Mar, 2007 | Pubmed ID: 17311849 Die Tumorsuppressor Smad4 Ist Erforderlich Für Transformierende Wachstumsfaktor Beta-induzierte Epitheliale, Mesenchymale Übergang Und Knochen Metastasierung Von Brustkrebszellen Cancer Research. Feb, 2006 | Pubmed ID: 16489022 Deubiquitinase Activity Profiling Identifies UCHL1 As a Candidate Oncoprotein That Promotes TGFβ-Induced Breast Cancer Metastasis Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. | Pubmed ID: 31857432 Untersuchung von TGF-β Signalisierung und TGF-β-induzierten epitheliaal-mesenchymalen Übergang bei Brustkrebs und normalen Zellen Jing Zhang1, Midory Thorikay1, Gerard van der Zon1, Maarten van Dinther1, Peter ten Dijke1 1Oncode Institute and Department of Cell Chemical Biology, Leiden University Medical Center JoVE 61830 Cancer Research
Untersuchung von TGF-β Signalisierung und TGF-β-induzierten epitheliaal-mesenchymalen Übergang bei Brustkrebs und normalen Zellen Jing Zhang1, Midory Thorikay1, Gerard van der Zon1, Maarten van Dinther1, Peter ten Dijke1 1Oncode Institute and Department of Cell Chemical Biology, Leiden University Medical Center JoVE 61830 Cancer Research