Mark L. Siegal Center for Genomics and Systems Biology, Department of Biology New York University Biography Publications Institution JoVE Articles Mark L. Siegal has not added a biography. If you are Mark L. Siegal and would like to personalize this page please email our Author Liaison for assistance. Publications Extent and Context Dependence of Pleiotropy Revealed by High-throughput Single-cell Phenotyping PLoS Biology. 08, 2020 | Pubmed ID: 32804946 A Standardized Nomenclature and Atlas of the Male Terminalia of Fly. Mar - Dec, 2019 | Pubmed ID: 31401934 Feed-forward Regulation Adaptively Evolves Via Dynamics Rather Than Topology when There is Intrinsic Noise Nature Communications. 06, 2019 | Pubmed ID: 31160574 Author Correction: Testing the Key Assumption of Heritability Estimates Based on Genome-wide Genetic Relatedness Journal of Human Genetics. 06, 2019 | Pubmed ID: 30940889 Decanalizing Thinking on Genetic Canalization Seminars in Cell & Developmental Biology. 04, 2019 | Pubmed ID: 29751086 Control of Nongenetic Heterogeneity in Growth Rate and Stress Tolerance of Saccharomyces Cerevisiae by Cyclic AMP-regulated Transcription Factors PLoS Genetics. 11, 2018 | Pubmed ID: 30388117 A Sibling Method for Identifying VQTLs PloS One. 2018 | Pubmed ID: 29617452 Deep Sequencing of Natural and Experimental Populations of Reveals Biases in the Spectrum of New Mutations Genome Research. 12, 2017 | Pubmed ID: 29079675 Resolving the Complex Genetic Basis of Phenotypic Variation and Variability of Cellular Growth Genetics. 07, 2017 | Pubmed ID: 28495957 Molecular Genetics: Chaperone Protein Gets Personal Nature. 05, 2017 | Pubmed ID: 28424517 Selection Transforms the Landscape of Genetic Variation Interacting with Hsp90 PLoS Biology. Oct, 2016 | Pubmed ID: 27768682 Sibling Genes As Environment: Sibling Dopamine Genotypes and Adolescent Health Support Frequency Dependent Selection Social Science Research. Nov, 2015 | Pubmed ID: 26463544 Engineering and Biology: Counsel for a Continued Relationship Biological Theory. Mar, 2015 | Pubmed ID: 26085824 A Philosophical Perspective on Evolutionary Systems Biology Biological Theory. Mar, 2015 | Pubmed ID: 26085823 Shifting Sugars and Shifting Paradigms PLoS Biology. Feb, 2015 | Pubmed ID: 25688600 Essential Gene Disruptions Reveal Complex Relationships Between Phenotypic Robustness, Pleiotropy, and Fitness Molecular Systems Biology. Jan, 2015 | Pubmed ID: 25609648 On the Nature and Evolutionary Impact of Phenotypic Robustness Mechanisms Annual Review of Ecology, Evolution, and Systematics. Nov, 2014 | Pubmed ID: 26034410 Reply to Chen and Zhang: On Interpreting Genome-wide Trends from Yeast Mutation Accumulation Data Proceedings of the National Academy of Sciences of the United States of America. Sep, 2014 | Pubmed ID: 25217565 The Genetics of Sex: Exploring Differences Genetics. Jun, 2014 | Pubmed ID: 24939993 The Genetics of Sex: Exploring Differences G3 (Bethesda, Md.). Jun, 2014 | Pubmed ID: 24939183 Precise Estimates of Mutation Rate and Spectrum in Yeast Proceedings of the National Academy of Sciences of the United States of America. Jun, 2014 | Pubmed ID: 24847077 Testing the Key Assumption of Heritability Estimates Based on Genome-wide Genetic Relatedness Journal of Human Genetics. Jun, 2014 | Pubmed ID: 24599117 Histone Variant HTZ1 Shows Extensive Epistasis With, but Does Not Increase Robustness To, New Mutations PLoS Genetics. 2013 | Pubmed ID: 23990806 Genetic and Nongenetic Determinants of Cell Growth Variation Assessed by High-Throughput Microscopy Molecular Biology and Evolution. Sep, 2013 | Pubmed ID: 23938868 Heritability and the Equal Environments Assumption: Evidence from Multiple Samples of Misclassified Twins Behavior Genetics. Sep, 2013 | Pubmed ID: 23903437 Beyond Orchids and Dandelions: Testing the 5-HTT "risky" Allele for Evidence of Phenotypic Capacitance and Frequency-dependent Selection Biodemography and Social Biology. 2013 | Pubmed ID: 23701535 Crouching Variation Revealed Molecular Ecology. Mar, 2013 | Pubmed ID: 23437837 Oh, the Places They'll Go: Female Sperm Storage and Sperm Precedence in Drosophila Melanogaster Spermatogenesis. Jul, 2012 | Pubmed ID: 23087839 Polygenic Cis-regulatory Adaptation in the Evolution of Yeast Pathogenicity Genome Research. Oct, 2012 | Pubmed ID: 22645260 Pausing on the Path to Robustness Developmental Cell. May, 2012 | Pubmed ID: 22595664 Bet Hedging in Yeast by Heterogeneous, Age-correlated Expression of a Stress Protectant PLoS Biology. 2012 | Pubmed ID: 22589700 Hsp90 Depletion Goes Wild BMC Biology. Feb, 2012 | Pubmed ID: 22369621 Sperm-storage Defects and Live Birth in Drosophila Females Lacking Spermathecal Secretory Cells PLoS Biology. Nov, 2011 | Pubmed ID: 22087073 The Female-specific Doublesex Isoform Regulates Pleiotropic Transcription Factors to Pattern Genital Development in Drosophila Development (Cambridge, England). Mar, 2011 | Pubmed ID: 21343364 Correlating Gene Expression Variation with Cis-regulatory Polymorphism in Saccharomyces Cerevisiae Genome Biology and Evolution. 2010 | Pubmed ID: 20829281 Robustness: Mechanisms and Consequences Trends in Genetics : TIG. Sep, 2009 | Pubmed ID: 19717203 Reexamining MicroRNA Site Accessibility in Drosophila: a Population Genomics Study PloS One. May, 2009 | Pubmed ID: 19478854 Network Hubs Buffer Environmental Variation in Saccharomyces Cerevisiae PLoS Biology. Nov, 2008 | Pubmed ID: 18986213 Functional and Evolutionary Inference in Gene Networks: Does Topology Matter? Genetica. Jan, 2007 | Pubmed ID: 16897451 Functional Conservation and Divergence of Intersex, a Gene Required for Female Differentiation in Drosophila Melanogaster Development Genes and Evolution. Jan, 2005 | Pubmed ID: 15645316 High-Throughput Live Imaging af mikrokolonier til måling af heterogenitet i vækst og genekspression Federica M. O. Sartori1, Cassandra Buzby1, Yevgeniy Plavskin1, Mark L. Siegal1 1Center for Genomics and Systems Biology, Department of Biology, New York University JoVE 62038 Biology
High-Throughput Live Imaging af mikrokolonier til måling af heterogenitet i vækst og genekspression Federica M. O. Sartori1, Cassandra Buzby1, Yevgeniy Plavskin1, Mark L. Siegal1 1Center for Genomics and Systems Biology, Department of Biology, New York University JoVE 62038 Biology