In JoVE (1)
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Articles by Mary Paige Lamprecht in JoVE
Using Human Induced Pluripotent Stem Cell-derived Hepatocyte-like Cells for Drug Discovery Jui-Tung Liu1, Mary Paige Lamprecht1, Stephen A. Duncan1 1Department of Regenerative Medicine and Cell Biology, Medical University of South Carolina The protocol presented here describes a platform for identifying small molecules for the treatment of liver disease. A step-by-step description is presented detailing how to differentiate iPSCs into cells with hepatocyte characteristics in 96-well plates, and to use the cells to screen for small molecules with potential therapeutic activity.