Matthew J. Lang Dept. of Chemical and Biomolecular Engineering Vanderbilt University Biography Publications Institution JoVE Articles Matthew J. Lang has not added a biography. If you are Matthew J. Lang and would like to personalize this page please email our Author Liaison for assistance. Publications Physical Properties of Polymorphic Yeast Prion Amyloid Fibers Biophysical Journal. Jul, 2011 | Pubmed ID: 21767497 Single-molecule Protein Unfolding and Translocation by an ATP-fueled Proteolytic Machine Cell. Apr, 2011 | Pubmed ID: 21496645 Quantification of Urinary Stone Volume: Attenuation Threshold-based CT Method--a Technical Note Radiology. Mar, 2011 | Pubmed ID: 21339353 A Microfluidic System with Optical Laser Tweezers to Study Mechanotransduction and Focal Adhesion Recruitment Lab on a Chip. Feb, 2011 | Pubmed ID: 21152510 Adhesion Through Single Peptide Aptamers The Journal of Physical Chemistry. A. Apr, 2011 | Pubmed ID: 20795685 Control and Manipulation of Pathogens with an Optical Trap for Live Cell Imaging of Intercellular Interactions PloS One. 2010 | Pubmed ID: 21217821 Optical Trapping with High Forces Reveals Unexpected Behaviors of Prion Fibrils Nature Structural & Molecular Biology. Dec, 2010 | Pubmed ID: 21113168 Molecular Origin of Strain Softening in Cross-linked F-actin Networks Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. Jul, 2010 | Pubmed ID: 20866660 Motor Proteins: Kinesin Drives with an Underhead Cam Current Biology : CB. May, 2010 | Pubmed ID: 20462483 Passive and Active Microrheology for Cross-linked F-actin Networks in Vitro Acta Biomaterialia. Apr, 2010 | Pubmed ID: 19883801 Single-molecule Denaturation and Degradation of Proteins by the AAA+ ClpXP Protease Proceedings of the National Academy of Sciences of the United States of America. Nov, 2009 | Pubmed ID: 19892734 The Alphabeta T Cell Receptor is an Anisotropic Mechanosensor The Journal of Biological Chemistry. Nov, 2009 | Pubmed ID: 19755427 Mechanical Design of Translocating Motor Proteins Cell Biochemistry and Biophysics. 2009 | Pubmed ID: 19452133 Kinesin's Cover-neck Bundle Folds Forward to Generate Force Proceedings of the National Academy of Sciences of the United States of America. Dec, 2008 | Pubmed ID: 19047639 Measuring Molecular Rupture Forces Between Single Actin Filaments and Actin-binding Proteins Proceedings of the National Academy of Sciences of the United States of America. Jul, 2008 | Pubmed ID: 18591676 Force Generation in Kinesin Hinges on Cover-neck Bundle Formation Structure (London, England : 1993). Jan, 2008 | Pubmed ID: 18184584 Active Particle Control Through Silicon Using Conventional Optical Trapping Techniques Lab on a Chip. Dec, 2007 | Pubmed ID: 18030409 Single M13 Bacteriophage Tethering and Stretching Proceedings of the National Academy of Sciences of the United States of America. Mar, 2007 | Pubmed ID: 17360403 Force of an Actin Spring Biophysical Journal. May, 2007 | Pubmed ID: 17351007 Detecting Force-induced Molecular Transitions with Fluorescence Resonant Energy Transfer Angewandte Chemie (International Ed. in English). 2007 | Pubmed ID: 17279589 Interlaced Optical Force-fluorescence Measurements for Single Molecule Biophysics Biophysical Journal. Aug, 2006 | Pubmed ID: 16648165 Simultaneous, Coincident Optical Trapping and Single-molecule Fluorescence Nature Methods. Nov, 2004 | Pubmed ID: 15782176 Resource Letter: LBOT-1: Laser-based Optical Tweezers American Journal of Physics. Mar, 2003 | Pubmed ID: 16971965 Combined Optical Trapping and Single-molecule Fluorescence Journal of Biology. 2003 | Pubmed ID: 12733997 Probing the Kinesin Reaction Cycle with a 2D Optical Force Clamp Proceedings of the National Academy of Sciences of the United States of America. Mar, 2003 | Pubmed ID: 12591957 An Automated Two-dimensional Optical Force Clamp for Single Molecule Studies Biophysical Journal. Jul, 2002 | Pubmed ID: 12080136 Use of an Optical Trap for Study of Host-Pathogen Interactions for Dynamic Live Cell Imaging Jenny M. Tam1, Carlos E. Castro2, Robert J. W. Heath3, Michael K. Mansour1, Michael L. Cardenas1, Ramnik J. Xavier3, Matthew J. Lang4, Jatin M. Vyas1 1Department of Medicine, Division of Infectious Diseases, Massachusetts General Hospital, Harvard Medical School, 2Department of Mechanical and Aerospace Engineering, The Ohio State University, 3Center for Computational and Integrative Biology, Massachusetts General Hospital, Harvard Medical School, 4Dept. of Chemical and Biomolecular Engineering, Vanderbilt University JoVE 3123 Immunology and Infection
Use of an Optical Trap for Study of Host-Pathogen Interactions for Dynamic Live Cell Imaging Jenny M. Tam1, Carlos E. Castro2, Robert J. W. Heath3, Michael K. Mansour1, Michael L. Cardenas1, Ramnik J. Xavier3, Matthew J. Lang4, Jatin M. Vyas1 1Department of Medicine, Division of Infectious Diseases, Massachusetts General Hospital, Harvard Medical School, 2Department of Mechanical and Aerospace Engineering, The Ohio State University, 3Center for Computational and Integrative Biology, Massachusetts General Hospital, Harvard Medical School, 4Dept. of Chemical and Biomolecular Engineering, Vanderbilt University JoVE 3123 Immunology and Infection