Maureen Gannon

Publications

• The Beta Cell in Type 2 Diabetes
  Current Diabetes Reports. Aug, 2019  |   Pubmed ID: 31399863
• Differential Cell Susceptibilities to Kras in the Setting of Obstructive Chronic Pancreatitis
  Cellular and Molecular Gastroenterology and Hepatology. Jul, 2019  |   Pubmed ID: 31310834
• Extracellular Matrix-associated Factors Play Critical Roles in Regulating Pancreatic β-cell Proliferation and Survival
  Endocrinology. Jul, 2019  |   Pubmed ID: 31271410
• Pancreatic Ductal Deletion of Hnf1b Disrupts Exocrine Homeostasis, Leads to Pancreatitis, and Facilitates Tumorigenesis
  Cellular and Molecular Gastroenterology and Hepatology. Jun, 2019  |   Pubmed ID: 31229598
• Toll-like Receptors TLR2 and TLR4 Block the Replication of Pancreatic β Cells in Diet-induced Obesity
  Nature Immunology. Jun, 2019  |   Pubmed ID: 31110312
• Maternal Western-style Diet Affects Offspring Islet Composition and Function in a Non-human Primate Model of Maternal Over-nutrition
  Molecular Metabolism. Jul, 2019  |   Pubmed ID: 31036449
• Sex Modifies Placental Gene Expression in Response to Metabolic and Inflammatory Stress
  Placenta. Mar, 2019  |   Pubmed ID: 30955704
• Regulation of the Pancreatic Exocrine Differentiation Program and Morphogenesis by Onecut 1/Hnf6
  Cellular and Molecular Gastroenterology and Hepatology. 2019  |   Pubmed ID: 30831323
• A Call for Improved Reporting of Human Islet Characteristics in Research Articles
  Diabetes. Feb, 2019  |   Pubmed ID: 30552106
• A Call for Improved Reporting of Human Islet Characteristics in Research Articles
  Diabetologia. 02, 2019  |   Pubmed ID: 30547229
• Increases in Bioactive Lipids Accompany Early Metabolic Changes Associated with β-cell Expansion in Response to Short-term High-fat Diet
  American Journal of Physiology. Endocrinology and Metabolism. Dec, 2018  |   Pubmed ID: 30106624
• Sex Differences Underlying Pancreatic Islet Biology and Its Dysfunction
  Molecular Metabolism. 09, 2018  |   Pubmed ID: 29891438
• Synaptotagmin 4 Regulates Pancreatic β Cell Maturation by Modulating the Ca Sensitivity of Insulin Secretion Vesicles
  Developmental Cell. 05, 2018  |   Pubmed ID: 29656931
• Cooperative Function of Pdx1 and Oc1 in Multipotent Pancreatic Progenitors Impacts Postnatal Islet Maturation and Adaptability
  American Journal of Physiology. Endocrinology and Metabolism. 04, 2018  |   Pubmed ID: 29351489
• Gestational Diabetes Exacerbates Maternal Immune Activation Effects in the Developing Brain
  Molecular Psychiatry. 09, 2018  |   Pubmed ID: 28948973
• Developmental Programming of the Pancreatic Islet by Overnutrition
  Trends in Developmental Biology. 2017  |   Pubmed ID: 29657386
• The Liver
  Current Biology : CB. Nov, 2017  |   Pubmed ID: 29112863
• Vascular-derived Connective Tissue Growth Factor (Ctgf) is Critical for Pregnancy-induced β Cell Hyperplasia in Adult Mice
  Islets. 11, 2017  |   Pubmed ID: 29111856
• Opposing Effects of Prostaglandin E Receptors EP3 and EP4 on Mouse and Human β-cell Survival and Proliferation
  Molecular Metabolism. 06, 2017  |   Pubmed ID: 28580285
• Regulation of Pancreatic β-cell Function and Mass Dynamics by Prostaglandin Signaling
  Journal of Cell Communication and Signaling. Jun, 2017  |   Pubmed ID: 28132118
• Onecut Transcription Factors in Development and Disease
  Trends in Developmental Biology. 2016  |   Pubmed ID: 28018056
• Growth Hormone Mediates Its Protective Effect in Hepatic Apoptosis Through Hnf6
  PloS One. 2016  |   Pubmed ID: 27936029
• Unexpected Effects of the MIP-CreER Transgene and Tamoxifen on β-cell Growth in C57Bl6/J Male Mice
  Physiological Reports. Sep, 2016  |   Pubmed ID: 27670405
• Connective Tissue Growth Factor is Critical for Proper β-cell Function and Pregnancy-induced β-cell Hyperplasia in Adult Mice
  American Journal of Physiology. Endocrinology and Metabolism. Sep, 2016  |   Pubmed ID: 27460898
• HNF6 and Rev-erbα Integrate Hepatic Lipid Metabolism by Overlapping and Distinct Transcriptional Mechanisms
  Genes & Development. 07, 2016  |   Pubmed ID: 27445394
• Loss of Free Fatty Acid Receptor 2 Leads to Impaired Islet Mass and Beta Cell Survival
  Scientific Reports. Jun, 2016  |   Pubmed ID: 27324831
• Threshold-Dependent Cooperativity of Pdx1 and Oc1 in Pancreatic Progenitors Establishes Competency for Endocrine Differentiation and β-Cell Function
  Cell Reports. 06, 2016  |   Pubmed ID: 27292642
• Diabetes Caused by Elastase-Cre-Mediated Pdx1 Inactivation in Mice
  Scientific Reports. Feb, 2016  |   Pubmed ID: 26887806
• Sustained Expression of GLP-1 Receptor Differentially Modulates β-cell Functions in Diabetic and Nondiabetic Mice
  Biochemical and Biophysical Research Communications. Feb, 2016  |   Pubmed ID: 26854076
• The PGE2 EP3 Receptor Regulates Diet-Induced Adiposity in Male Mice
  Endocrinology. Jan, 2016  |   Pubmed ID: 26485614
• Macrophages Are Essential for CTGF-mediated Adult β-cell Proliferation After Injury
  Molecular Metabolism. Aug, 2015  |   Pubmed ID: 26266091
• Activation of FoxM1 Revitalizes the Replicative Potential of Aged β-Cells in Male Mice and Enhances Insulin Secretion
  Diabetes. Nov, 2015  |   Pubmed ID: 26251404
• Preserving Mafa Expression in Diabetic Islet β-cells Improves Glycemic Control in Vivo
  The Journal of Biological Chemistry. Mar, 2015  |   Pubmed ID: 25645923
• High-fat Diet-induced β-cell Proliferation Occurs Prior to Insulin Resistance in C57Bl/6J Male Mice
  American Journal of Physiology. Endocrinology and Metabolism. Apr, 2015  |   Pubmed ID: 25628421
• Connective Tissue Growth Factor Modulates Adult β-cell Maturity and Proliferation to Promote β-cell Regeneration in Mice
  Diabetes. Apr, 2015  |   Pubmed ID: 25392241
• Activated FoxM1 Attenuates Streptozotocin-mediated β-cell Death
  Molecular Endocrinology (Baltimore, Md.). Sep, 2014  |   Pubmed ID: 25073103
• Loss of HNF6 Expression Correlates with Human Pancreatic Cancer Progression
  Laboratory Investigation; a Journal of Technical Methods and Pathology. May, 2014  |   Pubmed ID: 24638272
• Connective Tissue Growth Factor (CTGF/CCN2) Negatively Regulates BMP-2 Induced Osteoblast Differentiation and Signaling
  Journal of Cellular Physiology. May, 2014  |   Pubmed ID: 24127409
• An Assay for Small Scale Screening of Candidate β Cell Proliferative Factors Using Intact Islets
  BioTechniques. Dec, 2013  |   Pubmed ID: 24344680
• Advancements and Challenges in Generating Accurate Animal Models of Gestational Diabetes Mellitus
  American Journal of Physiology. Endocrinology and Metabolism. Dec, 2013  |   Pubmed ID: 24085033
• Onecut1 is Essential for Horizontal Cell Genesis and Retinal Integrity
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Aug, 2013  |   Pubmed ID: 23926259
• A Physiological Role for Connective Tissue Growth Factor in Early Wound Healing
  Laboratory Investigation; a Journal of Technical Methods and Pathology. Jan, 2013  |   Pubmed ID: 23212098
• The Skeletal Site-specific Role of Connective Tissue Growth Factor in Prenatal Osteogenesis
  Developmental Dynamics : an Official Publication of the American Association of Anatomists. Dec, 2012  |   Pubmed ID: 23073844
• Inactivation of the Dual Bmp/Wnt Inhibitor Sostdc1 Enhances Pancreatic Islet Function
  American Journal of Physiology. Endocrinology and Metabolism. Sep, 2012  |   Pubmed ID: 22829579
• Differential Regulation of Embryonic and Adult β Cell Replication
  Cell Cycle (Georgetown, Tex.). Jul, 2012  |   Pubmed ID: 22659844
• Tamoxifen-Induced Cre-loxP Recombination Is Prolonged in Pancreatic Islets of Adult Mice
  PloS One. 2012  |   Pubmed ID: 22470452
• Genetic Interactions Between Hepatocyte Nuclear Factor-6 and Notch Signaling Regulate Mouse Intrahepatic Bile Duct Development in Vivo
  Hepatology (Baltimore, Md.). Jan, 2012  |   Pubmed ID: 21898486
• Connective Tissue Growth Factor Acts Within Both Endothelial Cells and Beta Cells to Promote Proliferation of Developing Beta Cells
  Proceedings of the National Academy of Sciences of the United States of America. Sep, 2011  |   Pubmed ID: 21876171
• Type 2 Diabetes and the Aging Pancreatic Beta Cell
  Aging. Jun, 2011  |   Pubmed ID: 21765202
• Diet-induced Impaired Glucose Tolerance and Gestational Diabetes in the Dog
  Journal of Applied Physiology (Bethesda, Md. : 1985). Feb, 2011  |   Pubmed ID: 21088210
• Conditional Gene Targeting in Mouse Pancreatic ß-Cells: Analysis of Ectopic Cre Transgene Expression in the Brain
  Diabetes. Dec, 2010  |   Pubmed ID: 20802254
• OASIS/CREB3L1 Induces Expression of Genes Involved in Extracellular Matrix Production but Not Classical Endoplasmic Reticulum Stress Response Genes in Pancreatic Beta-cells
  Endocrinology. Sep, 2010  |   Pubmed ID: 20668028
• Adult Pancreatic Acinar Cells Give Rise to Ducts but Not Endocrine Cells in Response to Growth Factor Signaling
  Development (Cambridge, England). Jul, 2010  |   Pubmed ID: 20534672
• Gestational Diabetes Mellitus Resulting from Impaired Beta-cell Compensation in the Absence of FoxM1, a Novel Downstream Effector of Placental Lactogen
  Diabetes. Jan, 2010  |   Pubmed ID: 19833884
• Bioluminescence Imaging in Mouse Models Quantifies Beta Cell Mass in the Pancreas and After Islet Transplantation
  Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging. Jan-Feb, 2010  |   Pubmed ID: 19548035
• Multiple, Temporal-specific Roles for HNF6 in Pancreatic Endocrine and Ductal Differentiation
  Mechanisms of Development. Dec, 2009  |   Pubmed ID: 19766716
• Pancreas Cell Fate
  Birth Defects Research. Part C, Embryo Today : Reviews. Sep, 2009  |   Pubmed ID: 19750517
• Connective Tissue Growth Factor (CTGF) Inactivation Leads to Defects in Islet Cell Lineage Allocation and Beta-cell Proliferation During Embryogenesis
  Molecular Endocrinology (Baltimore, Md.). Mar, 2009  |   Pubmed ID: 19131512
• Regulation of Pancreas Plasticity and Malignant Transformation by Akt Signaling
  Gastroenterology. Mar, 2009  |   Pubmed ID: 19121634
• Beta-cell Proliferation, but Not Neogenesis, Following 60% Partial Pancreatectomy is Impaired in the Absence of FoxM1
  Diabetes. Nov, 2008  |   Pubmed ID: 18728229
• Gene Expression Profiling of a Mouse Model of Pancreatic Islet Dysmorphogenesis
  PloS One. Feb, 2008  |   Pubmed ID: 18297134
• Pdx-1 Function is Specifically Required in Embryonic Beta Cells to Generate Appropriate Numbers of Endocrine Cell Types and Maintain Glucose Homeostasis
  Developmental Biology. Feb, 2008  |   Pubmed ID: 18155690
• Deficiency of Endothelial Nitric-oxide Synthase Confers Susceptibility to Diabetic Nephropathy in Nephropathy-resistant Inbred Mice
  The American Journal of Pathology. May, 2007  |   Pubmed ID: 17456755
• Ptf1a Binds to and Activates Area III, a Highly Conserved Region of the Pdx1 Promoter That Mediates Early Pancreas-wide Pdx1 Expression
  Molecular and Cellular Biology. Jun, 2007  |   Pubmed ID: 17403901
• BuMP-ing Up Insulin Secretion by Pancreatic Beta Cells
  Cell Metabolism. Mar, 2007  |   Pubmed ID: 17339021
• Molecular Regulation of Pancreatic Beta-cell Mass Development, Maintenance, and Expansion
  Journal of Molecular Endocrinology. Feb, 2007  |   Pubmed ID: 17293440
• Maintenance of Hepatic Nuclear Factor 6 in Postnatal Islets Impairs Terminal Differentiation and Function of Beta-cells
  Diabetes. Dec, 2006  |   Pubmed ID: 17130469
• Pancreatic Islet Production of Vascular Endothelial Growth Factor--a is Essential for Islet Vascularization, Revascularization, and Function
  Diabetes. Nov, 2006  |   Pubmed ID: 17065333
• Complementation Rescue of Pdx1 Null Phenotype Demonstrates Distinct Roles of Proximal and Distal Cis-regulatory Sequences in Pancreatic and Duodenal Expression
  Developmental Biology. Oct, 2006  |   Pubmed ID: 16962573
• Characterization of Diabetic Nephropathy in a Transgenic Model of Hypoinsulinemic Diabetes
  American Journal of Physiology. Renal Physiology. Dec, 2006  |   Pubmed ID: 16705146
• The FoxM1 Transcription Factor is Required to Maintain Pancreatic Beta-cell Mass
  Molecular Endocrinology (Baltimore, Md.). Aug, 2006  |   Pubmed ID: 16556734
• Targeted Deletion of a Cis-regulatory Region Reveals Differential Gene Dosage Requirements for Pdx1 in Foregut Organ Differentiation and Pancreas Formation
  Genes & Development. Jan, 2006  |   Pubmed ID: 16418487
• Efficient Recombination in Pancreatic Islets by a Tamoxifen-inducible Cre-recombinase
  Genesis (New York, N.Y. : 2000). Jul, 2005  |   Pubmed ID: 15986486
• The Proximal Islet-specific Glucose-6-phosphatase Catalytic Subunit-related Protein Autoantigen Promoter is Sufficient to Initiate but Not Maintain Transgene Expression in Mouse Islets in Vivo
  Diabetes. Jul, 2004  |   Pubmed ID: 15220199
• Intraislet Endothelial Cells Contribute to Revascularization of Transplanted Pancreatic Islets
  Diabetes. May, 2004  |   Pubmed ID: 15111502
• The Role of Pdx1 and HNF6 in Proliferation and Differentiation of Endocrine Precursors
  Diabetes/metabolism Research and Reviews. Mar-Apr, 2004  |   Pubmed ID: 15037986
• The Role of the Transcriptional Regulator Ptf1a in Converting Intestinal to Pancreatic Progenitors
  Nature Genetics. Sep, 2002  |   Pubmed ID: 12185368
• Conserved Sequences in a Tissue-specific Regulatory Region of the Pdx-1 Gene Mediate Transcription in Pancreatic Beta Cells: Role for Hepatocyte Nuclear Factor 3 Beta and Pax6
  Molecular and Cellular Biology. Jul, 2002  |   Pubmed ID: 12052878
• The PERK Eukaryotic Initiation Factor 2 Alpha Kinase is Required for the Development of the Skeletal System, Postnatal Growth, and the Function and Viability of the Pancreas
  Molecular and Cellular Biology. Jun, 2002  |   Pubmed ID: 11997520
• PDX:PBX Complexes Are Required for Normal Proliferation of Pancreatic Cells During Development
  Proceedings of the National Academy of Sciences of the United States of America. Jan, 2001  |   Pubmed ID: 11158595