Max Gassmann Institute of Veterinary Physiology and Zurich Center for Integrative Human Physiology University of Zurich Biography Publications Institution JoVE Articles Max Gassmann has not added a biography. If you are Max Gassmann and would like to personalize this page please email our Author Liaison for assistance. Publications Biological Aortic Valve Replacement: Advantages and Optimal Indications of Stentless Compared to Stented Valve Substitutes. A Review General Thoracic and Cardiovascular Surgery. Jan, 2018 | Pubmed ID: 29322433 Erythropoietin Enhances Kupffer Cell Number and Activity in the Challenged Liver Scientific Reports. Sep, 2017 | Pubmed ID: 28871174 Aquaporin 1 Controls the Functional Phenotype of Pulmonary Smooth Muscle Cells in Hypoxia-induced Pulmonary Hypertension Basic Research in Cardiology. May, 2017 | Pubmed ID: 28409279 Protocol for a Prospective, Controlled, Observational Study to Evaluate the Influence of Hypoxia on Healthy Volunteers and Patients with Inflammatory Bowel Disease: the Altitude IBD Study BMJ Open. Jan, 2017 | Pubmed ID: 28057654 Analysis of Hypoxia-induced Noncoding RNAs Reveals Metastasis-associated Lung Adenocarcinoma Transcript 1 As an Important Regulator of Vascular Smooth Muscle Cell Proliferation Experimental Biology and Medicine (Maywood, N.J.). Mar, 2017 | Pubmed ID: 28056547 Improved Human Erythropoiesis and Platelet Formation in Humanized NSGW41 Mice Stem Cell Reports. Oct, 2016 | Pubmed ID: 27618723 Hypercapnic Ventilatory Response is Decreased in a Mouse Model of Excessive Erythrocytosis American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Nov, 2016 | Pubmed ID: 27605561 Kinetic MRNA Profiling in a Rat Model of Left-Ventricular Hypertrophy Reveals Early Expression of Chemokines and Their Receptors PloS One. 2016 | Pubmed ID: 27525724 Cardiac N-methyl D-aspartate Receptors As a Pharmacological Target Journal of Cardiovascular Pharmacology. Nov, 2016 | Pubmed ID: 27525575 Pregnancy at High Altitude in the Andes Leads to Increased Total Vessel Density in Healthy Newborns Journal of Applied Physiology (Bethesda, Md. : 1985). Sep, 2016 | Pubmed ID: 27445300 Comparing the Impact of an Acute Exercise Bout on Plasma Amino Acid Composition, Intraerythrocytic Ca(2+) Handling, and Red Cell Function in Athletes and Untrained Subjects Cell Calcium. Oct, 2016 | Pubmed ID: 27292137 Increased EPO Levels Are Associated With Bone Loss in Mice Lacking PHD2 in EPO-Producing Cells Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Oct, 2016 | Pubmed ID: 27082941 Temporal Rac1 - HIF-1 Crosstalk Modulates Hypoxic Survival of Aged Neurons Brain Research. Jul, 2016 | Pubmed ID: 27018294 Moderate Hypothermia During Ex Vivo Machine Perfusion Promotes Recovery of Hearts Donated After Cardiocirculatory Death† European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery. Jan, 2016 | Pubmed ID: 25740820 Neuronal Erythropoietin Overexpression Protects Mice Against Age-related Hearing Loss (presbycusis) Neurobiology of Aging. Dec, 2015 | Pubmed ID: 26364734 Elevated Hepcidin Serum Level in Response to Inflammatory and Iron Signals in Exercising Athletes is Independent of Moderate Supplementation with Vitamin C and E Physiological Reports. Aug, 2015 | Pubmed ID: 26243212 Adaptation of Iron Requirement to Hypoxic Conditions at High Altitude Journal of Applied Physiology (Bethesda, Md. : 1985). Dec, 2015 | Pubmed ID: 26183475 PHYSIOLOGY. Regulation of Breathing by CO₂ Requires the Proton-activated Receptor GPR4 in Retrotrapezoid Nucleus Neurons Science (New York, N.Y.). Jun, 2015 | Pubmed ID: 26068853 Differential Responses of Blood-brain Barrier Associated Cells to Hypoxia and Ischemia: a Comparative Study Fluids and Barriers of the CNS. Feb, 2015 | Pubmed ID: 25879623 Featured Article: MicroRNA-125a in Pulmonary Hypertension: Regulator of a Proliferative Phenotype of Endothelial Cells Experimental Biology and Medicine (Maywood, N.J.). Dec, 2015 | Pubmed ID: 25854878 Functional Plasticity of the N-methyl-d-aspartate Receptor in Differentiating Human Erythroid Precursor Cells American Journal of Physiology. Cell Physiology. Jun, 2015 | Pubmed ID: 25788577 The Effects of Short-term and Long-term Testosterone Supplementation on Blood Viscosity and Erythrocyte Deformability in Healthy Adult Mice Endocrinology. May, 2015 | Pubmed ID: 25774550 The Hypoxia-induced MicroRNA-130a Controls Pulmonary Smooth Muscle Cell Proliferation by Directly Targeting CDKN1A The International Journal of Biochemistry & Cell Biology. Apr, 2015 | Pubmed ID: 25681685 Erythropoietin Directly Stimulates Osteoclast Precursors and Induces Bone Loss FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. May, 2015 | Pubmed ID: 25630969 Erythropoietin's Inhibiting Impact on Hepcidin Expression Occurs Indirectly American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Feb, 2015 | Pubmed ID: 25519735 Novel Antibodies Directed Against the Human Erythropoietin Receptor: Creating a Basis for Clinical Implementation British Journal of Haematology. Feb, 2015 | Pubmed ID: 25283956 Arginine-vasopressin Marker Copeptin is a Sensitive Plasma Surrogate of Hypoxic Exposure Hypoxia (Auckland, N.Z.). 2014 | Pubmed ID: 27774473 Mice Over-expressing Human Erythropoietin Indicate That Erythropoietin Enhances Expression of Its Receptor Via Up-regulated Gata1 and Tal1 Haematologica. Oct, 2014 | Pubmed ID: 25085352 Red Blood Cells of Sickle Cell Disease Patients Exhibit Abnormally High Abundance of N-methyl D-aspartate Receptors Mediating Excessive Calcium Uptake British Journal of Haematology. Oct, 2014 | Pubmed ID: 25041184 Downregulation of Duodenal SLC Transporters and Activation of Proinflammatory Signaling Constitute the Early Response to High Altitude in Humans American Journal of Physiology. Gastrointestinal and Liver Physiology. Oct, 2014 | Pubmed ID: 24970780 Multikinase Inhibitor Sorafenib Prevents Pressure Overload-induced Left Ventricular Hypertrophy in Rats by Blocking the C-Raf/ERK1/2 Signaling Pathway Journal of Cardiothoracic Surgery. May, 2014 | Pubmed ID: 24885948 Hypoxia Selectively Disrupts Brain Microvascular Endothelial Tight Junction Complexes Through a Hypoxia-inducible Factor-1 (HIF-1) Dependent Mechanism Journal of Cellular Physiology. Aug, 2014 | Pubmed ID: 24375098 Restraint Stress Enhances Arterial Thrombosis in Vivo--role of the Sympathetic Nervous System Stress (Amsterdam, Netherlands). Jan, 2014 | Pubmed ID: 24215418 Loss of Prolyl Hydroxylase-2 in Myeloid Cells and T-lymphocytes Impairs Tumor Development International Journal of Cancer. Feb, 2014 | Pubmed ID: 23913502 AntagomiR Directed Against MiR-20a Restores Functional BMPR2 Signalling and Prevents Vascular Remodelling in Hypoxia-induced Pulmonary Hypertension European Heart Journal. Dec, 2014 | Pubmed ID: 22450430 Combination of Erythropoietin and Sildenafil Can Effectively Attenuate Hypoxia-induced Pulmonary Hypertension in Mice Pulmonary Circulation. Dec, 2013 | Pubmed ID: 25006406 Presence of the Gpr179(nob5) Allele in a C3H-derived Transgenic Mouse Molecular Vision. 2013 | Pubmed ID: 24415894 Decreased Stability of Erythroblastic Islands in Integrin β3-deficient Mice Physiological Reports. Jul, 2013 | Pubmed ID: 24303107 Reduced Insulin Sensitivity As a Marker for Acute Mountain Sickness? High Altitude Medicine & Biology. Sep, 2013 | Pubmed ID: 24067185 N-methyl-D-aspartate Receptors in Human Erythroid Precursor Cells and in Circulating Red Blood Cells Contribute to the Intracellular Calcium Regulation American Journal of Physiology. Cell Physiology. Dec, 2013 | Pubmed ID: 24048732 Neuropilin-1 Modulates Vascular Endothelial Growth Factor-induced Poly(ADP-ribose)-polymerase Leading to Reduced Cerebrovascular Apoptosis Neurobiology of Disease. Nov, 2013 | Pubmed ID: 23816753 Adaptation of Iron Transport and Metabolism to Acute High-altitude Hypoxia in Mountaineers Hepatology (Baltimore, Md.). Dec, 2013 | Pubmed ID: 23787477 Liver Iron Modulates Hepcidin Expression During Chronically Elevated Erythropoiesis in Mice Hepatology (Baltimore, Md.). Dec, 2013 | Pubmed ID: 23744538 Erythrocytosis: the HIF Pathway in Control Blood. Aug, 2013 | Pubmed ID: 23733342 Erythropoietin Contributes to Slow Oxidative Muscle Fiber Specification Via PGC-1α and AMPK Activation The International Journal of Biochemistry & Cell Biology. Jul, 2013 | Pubmed ID: 23523698 Using Plethysmography to Determine Erythropoietin's Impact on Neural Control of Ventilation Methods in Molecular Biology (Clifton, N.J.). 2013 | Pubmed ID: 23456876 Fast-twitch Glycolytic Skeletal Muscle is Predisposed to Age-induced Impairments in Mitochondrial Function The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. Sep, 2013 | Pubmed ID: 23371970 HIF-1α is a Protective Factor in Conditional PHD2-deficient Mice Suffering from Severe HIF-2α-induced Excessive Erythropoiesis Blood. Feb, 2013 | Pubmed ID: 23264599 Evidence of Synergistic/additive Effects of Sildenafil and Erythropoietin in Enhancing Survival and Migration of Hypoxic Endothelial Cells American Journal of Physiology. Lung Cellular and Molecular Physiology. Feb, 2013 | Pubmed ID: 23204066 The C57Bl/6 Mouse Serves As a Suitable Model of Human Skeletal Muscle Mitochondrial Function Experimental Physiology. Apr, 2013 | Pubmed ID: 23180810 Leh Symposium 2012 and PVRI India Annual Symposium High Altitude Medicine & Biology. Dec, 2012 | Pubmed ID: 23270450 The Hypoxic Placenta High Altitude Medicine & Biology. Sep, 2012 | Pubmed ID: 22994517 Cross Talk Between S-nitrosylation and S-glutathionylation in Control of the Na,K-ATPase Regulation in Hypoxic Heart American Journal of Physiology. Heart and Circulatory Physiology. Dec, 2012 | Pubmed ID: 22982781 S-glutathionylation of the Na,K-ATPase Catalytic α Subunit is a Determinant of the Enzyme Redox Sensitivity The Journal of Biological Chemistry. Sep, 2012 | Pubmed ID: 22798075 Red Blood Cell Volume and the Capacity for Exercise at Moderate to High Altitude Sports Medicine (Auckland, N.Z.). Aug, 2012 | Pubmed ID: 22741918 Acute and Chronic Elevation of Erythropoietin in the Brain Improves Exercise Performance in Mice Without Inducing Erythropoiesis FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Sep, 2012 | Pubmed ID: 22683849 Involvement of Oxidative Stress in Hypoxia-induced Blood-brain Barrier Breakdown Microvascular Research. Sep, 2012 | Pubmed ID: 22668821 Disturbed Eating at High Altitude: Influence of Food Preferences, Acute Mountain Sickness and Satiation Hormones European Journal of Nutrition. May, 2012 | Pubmed ID: 22573211 Acute Hypoxia Modifies Regulation of Neuroglobin in the Neonatal Mouse Brain Experimental Neurology. Jul, 2012 | Pubmed ID: 22548980 Endogenous Erythropoietin Signaling Facilitates Skeletal Muscle Repair and Recovery Following Pharmacologically Induced Damage FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jul, 2012 | Pubmed ID: 22490927 The Impact of Hypoxia on Cells, Mice, and Men High Altitude Medicine & Biology. Mar, 2012 | Pubmed ID: 22429236 Systemic Hypoxia Differentially Affects Neurogenesis During Early Mouse Brain Maturation Brain & Development. Apr, 2012 | Pubmed ID: 21824737 Interleukin-6 Enhances Insulin Secretion by Increasing Glucagon-like Peptide-1 Secretion from L Cells and Alpha Cells Nature Medicine. Oct, 2011 | Pubmed ID: 22037645 Interaction of HIF and USF Signaling Pathways in Human Genes Flanked by Hypoxia-response Elements and E-box Palindromes Molecular Cancer Research : MCR. Nov, 2011 | Pubmed ID: 21984181 Endogenous Myoglobin in Breast Cancer is Hypoxia-inducible by Alternative Transcription and Functions to Impair Mitochondrial Activity: a Role in Tumor Suppression? The Journal of Biological Chemistry. Dec, 2011 | Pubmed ID: 21930697 Hypoxia is Present in Murine Atherosclerotic Plaques and Has Multiple Adverse Effects on Macrophage Lipid Metabolism Circulation Research. Oct, 2011 | Pubmed ID: 21921268 Excessive Erythrocytosis Compromises the Blood-endothelium Interface in Erythropoietin-overexpressing Mice The Journal of Physiology. Nov, 2011 | Pubmed ID: 21859826 Oxygen 2011 High Altitude Medicine & Biology. 2011 | Pubmed ID: 21718167 Hypoxia: Adapting to High Altitude by Mutating EPAS-1, the Gene Encoding HIF-2α High Altitude Medicine & Biology. 2011 | Pubmed ID: 21718164 Interventricular Heterogeneity in Rat Heart Responses to Hypoxia: the Tuning of Glucose Metabolism, Ion Gradients, and Function American Journal of Physiology. Heart and Circulatory Physiology. May, 2011 | Pubmed ID: 21398597 Erythropoietic and Non-erythropoietic Functions of Erythropoietin in Mouse Models The Journal of Physiology. Mar, 2011 | Pubmed ID: 21282290 Post-acute Delivery of Erythropoietin Induces Stroke Recovery by Promoting Perilesional Tissue Remodelling and Contralesional Pyramidal Tract Plasticity Brain : a Journal of Neurology. Jan, 2011 | Pubmed ID: 21186263 Cdk5 Interacts with Hif-1α in Neurons: a New Hypoxic Signalling Mechanism? Brain Research. Mar, 2011 | Pubmed ID: 20977891 Astrocytes and Pericytes Differentially Modulate Blood-brain Barrier Characteristics During Development and Hypoxic Insult Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Feb, 2011 | Pubmed ID: 20827262 The Role of Excessive Versus Acute Administration of Erythropoietin in Attenuating Hepatic Ischemia-reperfusion Injury Canadian Journal of Physiology and Pharmacology. Dec, 2010 | Pubmed ID: 21164559 Late-gestational Systemic Hypoxia Leads to a Similar Early Gene Response in Mouse Placenta and Developing Brain American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Dec, 2010 | Pubmed ID: 20926767 Impaired Ventilatory Acclimatization to Hypoxia in Female Mice Overexpressing Erythropoietin: Unexpected Deleterious Effect of Estradiol in Carotid Bodies American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Dec, 2010 | Pubmed ID: 20861276 Erythropoietin: Not Just About Erythropoiesis Lancet. Jun, 2010 | Pubmed ID: 20609950 Macrophages As Novel Target Cells for Erythropoietin Haematologica. Nov, 2010 | Pubmed ID: 20595096 Functional NMDA Receptors in Rat Erythrocytes American Journal of Physiology. Cell Physiology. Jun, 2010 | Pubmed ID: 20457837 Oxygen-induced Regulation of the Intracellular Glutathione Levels in Erythrocytes European Journal of Applied Physiology. Jun, 2010 | Pubmed ID: 20091336 Erythropoietin Treatment Leads to Reduced Blood Glucose Levels and Body Mass: Insights from Murine Models The Journal of Endocrinology. Apr, 2010 | Pubmed ID: 20061512 Optimal Hematocrit for Maximal Exercise Performance in Acute and Chronic Erythropoietin-treated Mice Proceedings of the National Academy of Sciences of the United States of America. Jan, 2010 | Pubmed ID: 19966291 The Neuronal Control of Hypoxic Ventilation: Erythropoietin and Sexual Dimorphism Annals of the New York Academy of Sciences. Oct, 2009 | Pubmed ID: 19845617 Erythropoietin but Not VEGF Has a Protective Effect on Auditory Hair Cells in the Inner Ear Cellular and Molecular Life Sciences : CMLS. Nov, 2009 | Pubmed ID: 19763398 Erythropoietin Modulates the Neural Control of Hypoxic Ventilation Cellular and Molecular Life Sciences : CMLS. Nov, 2009 | Pubmed ID: 19756385 The Impact of Hypoxia on Our Body: from Integrative Physiology to Human Disease Cellular and Molecular Life Sciences : CMLS. Nov, 2009 | Pubmed ID: 19730799 Mast Cells and Macrophages in Duodenal Mucosa of Mice Overexpressing Erythropoietin Journal of Anatomy. Nov, 2009 | Pubmed ID: 19691658 Optimized Surgical Techniques and Postoperative Care Improve Survival Rates and Permit Accurate Telemetric Recording in Exercising Mice BMC Veterinary Research. 2009 | Pubmed ID: 19646283 Oxygen Sensing and the Activation of the Hypoxia Inducible Factor 1 (HIF-1)--invited Article Advances in Experimental Medicine and Biology. 2009 | Pubmed ID: 19536482 Quantifying Western Blots: Pitfalls of Densitometry Electrophoresis. Jun, 2009 | Pubmed ID: 19517440 Erythropoietin Activates Nitric Oxide Synthase in Murine Erythrocytes American Journal of Physiology. Cell Physiology. Aug, 2009 | Pubmed ID: 19515903 Short-term Effects of Pharmacologic HIF Stabilization on Vasoactive and Cytotrophic Factors in Developing Mouse Brain Brain Research. Jul, 2009 | Pubmed ID: 19450570 The Role of Hypoxia-inducible Transcription Factors in the Hypoxic Neonatal Brain Brain & Development. Aug, 2009 | Pubmed ID: 19398180 Non-erythroid Effects of Erythropoietin: Are Neutrophils a Target? Leukemia Research. Oct, 2009 | Pubmed ID: 19376577 Moderate Altitude but Not Additional Endurance Training Increases Markers of Oxidative Stress in Exhaled Breath Condensate European Journal of Applied Physiology. Jul, 2009 | Pubmed ID: 19363619 Sex-dependent Regulation of Hypoxic Ventilation in Mice and Humans is Mediated by Erythropoietin American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Jun, 2009 | Pubmed ID: 19321698 Erythropoietin Protects from Reperfusion-induced Myocardial Injury by Enhancing Coronary Endothelial Nitric Oxide Production European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery. May, 2009 | Pubmed ID: 19237290 Non-erythroid Activities of Erythropoietin: Functional Effects on Murine Dendritic Cells Molecular Immunology. Feb, 2009 | Pubmed ID: 19027957 Placental HIFs As Markers of Cerebral Hypoxic Distress in Fetal Mice American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Dec, 2008 | Pubmed ID: 18832080 Astrocyte Responses to Injury: VEGF Simultaneously Modulates Cell Death and Proliferation American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Sep, 2008 | Pubmed ID: 18614764 Ventilatory Responses to Acute and Chronic Hypoxia Are Altered in Female but Not Male Paskin-deficient Mice American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Aug, 2008 | Pubmed ID: 18509100 Poly(ADP-ribose) Polymerase 1 Promotes Tumor Cell Survival by Coactivating Hypoxia-inducible Factor-1-dependent Gene Expression Molecular Cancer Research : MCR. Feb, 2008 | Pubmed ID: 18314489 HIF-1-regulated Vasoactive Systems Are Differentially Involved in Acute Hypoxic Stress Responses of the Developing Brain of Newborn Mice and Are Not Affected by Levetiracetam Brain Research. Mar, 2008 | Pubmed ID: 18281021 Abortion in Mice with Excessive Erythrocytosis is Due to Impaired Arteriogenesis of the Uterine Arcade Biology of Reproduction. Jun, 2008 | Pubmed ID: 18256329 Oxygen Supply and Retinal Function: Insights from a Transgenic Animal Model Advances in Experimental Medicine and Biology. 2008 | Pubmed ID: 18188942 Novel Three-dimensional Analysis Tool for Vascular Trees Indicates Complete Micro-networks, Not Single Capillaries, As the Angiogenic Endpoint in Mice Overexpressing Human VEGF(165) in the Brain NeuroImage. Feb, 2008 | Pubmed ID: 18077185 Respiratory Plasticity in Response to Changes in Oxygen Supply and Demand Integrative and Comparative Biology. Oct, 2007 | Pubmed ID: 21672862 Nociceptive Tuning by Stem Cell Factor/c-Kit Signaling Neuron. Dec, 2007 | Pubmed ID: 18054864 Constitutively Overexpressed Erythropoietin Reduces Infarct Size in a Mouse Model of Permanent Coronary Artery Ligation Methods in Enzymology. 2007 | Pubmed ID: 17998053 Oxygen-induced Regulation of Na/K ATPase in Cerebellar Granule Cells The Journal of General Physiology. Oct, 2007 | Pubmed ID: 17893192 Acute and Chronic Exposure to Hypoxia Alters Ventilatory Pattern but Not Minute Ventilation of Mice Overexpressing Erythropoietin American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Oct, 2007 | Pubmed ID: 17652365 Soluble Erythropoietin Receptor is Present in the Mouse Brain and is Required for the Ventilatory Acclimatization to Hypoxia The Journal of Physiology. Aug, 2007 | Pubmed ID: 17584830 Enhanced Susceptibility to Suicidal Death of Erythrocytes from Transgenic Mice Overexpressing Erythropoietin American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Sep, 2007 | Pubmed ID: 17567717 Erythropoietin Enhances Immune Responses in Mice European Journal of Immunology. Jun, 2007 | Pubmed ID: 17458859 Simultaneous Application of the Vascular Endothelial Growth Factor (VEGF) Receptor Inhibitor PTK787/ZK 222584 and Ionizing Radiation Does Not Further Reduce the Growth of Canine Oral Melanoma Xenografts in Nude Mice Veterinary Journal (London, England : 1997). May, 2007 | Pubmed ID: 17449301 Enhanced Erythro-phagocytosis in Polycythemic Mice Overexpressing Erythropoietin Blood. Jul, 2007 | Pubmed ID: 17395782 Excessive Erythrocytosis Does Not Elevate Capillary Oxygen Delivery in Subcutaneous Mouse Tissue Microcirculation (New York, N.Y. : 1994). Feb, 2007 | Pubmed ID: 17365666 The Yeast Genome May Harbor Hypoxia Response Elements (HRE) Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP. Jul-Aug, 2007 | Pubmed ID: 17035097 Reduced Cerebral Blood Flow but Elevated Cerebral Glucose Metabolic Rate in Erythropoietin Overexpressing Transgenic Mice with Excessive Erythrocytosis Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Mar, 2007 | Pubmed ID: 16804549 Hypoxia-induced Gene Activity in Disused Oxidative Muscle Advances in Experimental Medicine and Biology. 2006 | Pubmed ID: 17089889 Hypoxic Preconditioning and Erythropoietin Protect Retinal Neurons from Degeneration Advances in Experimental Medicine and Biology. 2006 | Pubmed ID: 17089884 Regulating Cellular Oxygen Sensing by Hydroxylation Cardiovascular Research. Sep, 2006 | Pubmed ID: 16780822 Excessive Erythrocytosis in Adult Mice Overexpressing Erythropoietin Leads to Hepatic, Renal, Neuronal, and Muscular Degeneration American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Oct, 2006 | Pubmed ID: 16690772 Regulation of Cardiotrophin-1 Expression in Mouse Embryonic Stem Cells by HIF-1alpha and Intracellular Reactive Oxygen Species Journal of Cell Science. Mar, 2006 | Pubmed ID: 16507596 Sensing and Responding to Hypoxia Via HIF in Model Invertebrates Journal of Insect Physiology. Apr, 2006 | Pubmed ID: 16500673 The Effect of Erythropoietin on Gentamicin-induced Auditory Hair Cell Loss The Laryngoscope. Feb, 2006 | Pubmed ID: 16467726 Regular Endurance Training Reduces the Exercise Induced HIF-1alpha and HIF-2alpha MRNA Expression in Human Skeletal Muscle in Normoxic Conditions European Journal of Applied Physiology. Mar, 2006 | Pubmed ID: 16284786 Preserved Placental Oxygenation and Development During Severe Systemic Hypoxia American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Mar, 2006 | Pubmed ID: 16195499 Permanently Increased Conductance of the Murine Uterine Arcade After the First Pregnancy European Journal of Morphology. Oct-Dec, 2005 | Pubmed ID: 16982480 Congenital Erythropoietin Over-expression Causes "anti-pulmonary Hypertensive" Structural and Functional Changes in Mice, Both in Normoxia and Hypoxia Thrombosis and Haemostasis. Sep, 2005 | Pubmed ID: 16268482 Brain-derived Erythropoietin Protects from Focal Cerebral Ischemia by Dual Activation of ERK-1/-2 and Akt Pathways FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Dec, 2005 | Pubmed ID: 16207820 NF-kappaB Contributes to Transcription of Placenta Growth Factor and Interacts with Metal Responsive Transcription Factor-1 in Hypoxic Human Cells Biological Chemistry. Sep, 2005 | Pubmed ID: 16164411 Erythropoietin Regulates Hypoxic Ventilation in Mice by Interacting with Brainstem and Carotid Bodies The Journal of Physiology. Oct, 2005 | Pubmed ID: 16051624 Central Necrosis in Isolated Hypoxic Human Pancreatic Islets: Evidence for Postisolation Ischemia Cell Transplantation. 2005 | Pubmed ID: 15789664 Erythropoietin Protects from Axotomy-induced Degeneration of Retinal Ganglion Cells by Activating ERK-1/-2 FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Feb, 2005 | Pubmed ID: 15556972 HIF-1alpha Expression Follows Microvascular Loss in Advanced Murine Adriamycin Nephrosis American Journal of Physiology. Renal Physiology. Jan, 2005 | Pubmed ID: 15383400 HIF and VEGF Relationships in Response to Hypoxia and Sciatic Nerve Stimulation in Rat Gastrocnemius Respiratory Physiology & Neurobiology. Nov, 2004 | Pubmed ID: 15522704 Hypoxia Enhances Human B19 Erythrovirus Gene Expression in Primary Erythroid Cells Virology. Sep, 2004 | Pubmed ID: 15327892 High Altitude Training of Dogs Results in Elevated Erythropoietin and Endothelin-1 Serum Levels Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology. Jul, 2004 | Pubmed ID: 15313491 Constitutive Overexpression of Human Erythropoietin Protects the Mouse Retina Against Induced but Not Inherited Retinal Degeneration The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2004 | Pubmed ID: 15215287 Uncontrolled Expression of Vascular Endothelial Growth Factor and Its Receptors Leads to Insufficient Skin Angiogenesis in Patients with Systemic Sclerosis Circulation Research. Jul, 2004 | Pubmed ID: 15178641 Rescue of Lethal C-KitW/W Mice by Erythropoietin Blood. Sep, 2004 | Pubmed ID: 15178584 Simultaneous Exposure of Rats to Dioxin and Carbon Monoxide Reduces the Xenobiotic but Not the Hypoxic Response Biological Chemistry. Mar-Apr, 2004 | Pubmed ID: 15134343 Oxygenation of Spontaneous Canine Tumors During Fractionated Radiation Therapy Strahlentherapie Und Onkologie : Organ Der Deutschen Rontgengesellschaft ... [et Al]. May, 2004 | Pubmed ID: 15127160 Differentiating Embryonic Stem Cells into Embryoid Bodies Methods in Molecular Biology (Clifton, N.J.). 2004 | Pubmed ID: 15041757 HIFs and Tumors--causes and Consequences American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Apr, 2004 | Pubmed ID: 15003941 Physiologic Responses to Hypoxia and Implications for Hypoxia-inducible Factors in the Pathogenesis of Rheumatoid Arthritis Arthritis and Rheumatism. Jan, 2004 | Pubmed ID: 14730595 Non-erythroid Functions of Erythropoietin Advances in Experimental Medicine and Biology. 2003 | Pubmed ID: 14713131 Hypoxia and High Altitude. The Molecular Response Advances in Experimental Medicine and Biology. 2003 | Pubmed ID: 14713116 Molecular Mechanisms of Oxygen-induced Regulation of Na+/K+ Pump Advances in Experimental Medicine and Biology. 2003 | Pubmed ID: 14635672 Constitutive Upregulation of Hypoxia-inducible Factor-1alpha MRNA Occurring in Highly Metastatic Lung Carcinoma Cells Leads to Vascular Endothelial Growth Factor Overexpression Upon Hypoxic Exposure Oncogene. Oct, 2003 | Pubmed ID: 14555985 Differential Role of P300 and CBP Acetyltransferase During Myogenesis: P300 Acts Upstream of MyoD and Myf5 The EMBO Journal. Oct, 2003 | Pubmed ID: 14517256 Targeted Disruption of the Mouse PAS Domain Serine/threonine Kinase PASKIN Molecular and Cellular Biology. Oct, 2003 | Pubmed ID: 12972598 Defective Brain Development in Mice Lacking the Hif-1alpha Gene in Neural Cells Molecular and Cellular Biology. Oct, 2003 | Pubmed ID: 12972594 Transgenic Mice Overexpressing Erythropoietin Adapt to Excessive Erythrocytosis by Regulating Blood Viscosity Blood. Sep, 2003 | Pubmed ID: 12750170 Hemostasis and Coagulation at a Hematocrit Level of 0.85: Functional Consequences of Erythrocytosis Blood. Jun, 2003 | Pubmed ID: 12576335 Regulation of the Multidrug Resistance Transporter P-glycoprotein in Multicellular Tumor Spheroids by Hypoxia-inducible Factor (HIF-1) and Reactive Oxygen Species FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Mar, 2003 | Pubmed ID: 12514119 Erythropoietin-induced Excessive Erythrocytosis Activates the Tissue Endothelin System in Mice FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Feb, 2003 | Pubmed ID: 12490547 Expression of Hypoxia-inducible Factors in the Peri-implantation Mouse Uterus is Regulated in a Cell-specific and Ovarian Steroid Hormone-dependent Manner. Evidence for Differential Function of HIFs During Early Pregnancy The Journal of Biological Chemistry. Feb, 2003 | Pubmed ID: 12482866 Hypoxic Up-regulation of Erythroid 5-aminolevulinate Synthase Blood. Jan, 2003 | Pubmed ID: 12393745 Ultrasound Guided, Pre-radiation Oxygen Measurements Using Polarographic Oxygen Needle Electrodes in Spontaneous Canine Soft Tissue Sarcomas In Vivo (Athens, Greece). Nov-Dec, 2002 | Pubmed ID: 12494886 Characterization of HIF-1 Alpha Overexpressing HeLa Cells and Implications for Gene Therapy Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP. Dec, 2002 | Pubmed ID: 12458176 Viable C-Kit(W/W) Mutants Reveal Pivotal Role for C-kit in the Maintenance of Lymphopoiesis Immunity. Sep, 2002 | Pubmed ID: 12354381 Hypoxic Induction of Hypoxia-inducible Factor-1alpha and Oxygen-regulated Gene Expression in Mitochondrial DNA-depleted HeLa Cells Biochemical and Biophysical Research Communications. Sep, 2002 | Pubmed ID: 12237125 Hypoxic Pulmonary Artery Fibroblasts Trigger Proliferation of Vascular Smooth Muscle Cells: Role of Hypoxia-inducible Transcription Factors FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Oct, 2002 | Pubmed ID: 12207001 Pattern of Prepro-endothelin-1 Expression Revealed by Reporter-gene Activity in Kidneys of Erythropoietin-overexpressing Mice Clinical Science (London, England : 1979). Aug, 2002 | Pubmed ID: 12193052 DNA-binding Activity of Hypoxia-inducible Factors (HIFs) Methods in Molecular Biology (Clifton, N.J.). 2002 | Pubmed ID: 12152189 Extracellular Signal-regulated Protein Kinase Activation During Reoxygenation is Required to Restore Ischaemia-induced Endothelial Barrier Failure The Biochemical Journal. Nov, 2002 | Pubmed ID: 12137564 Cerebral Transcriptome Analysis of Transgenic Mice Overexpressing Erythropoietin Neuroscience Letters. Jul, 2002 | Pubmed ID: 12113907 HIF-1-induced Erythropoietin in the Hypoxic Retina Protects Against Light-induced Retinal Degeneration Nature Medicine. Jul, 2002 | Pubmed ID: 12068288 Rescue of Hypoxia-inducible Factor-1alpha-deficient Tumor Growth by Wild-type Cells is Independent of Vascular Endothelial Growth Factor Cancer Research. May, 2002 | Pubmed ID: 12019179 Apoptosis in Hypoxic Human Pancreatic Islets Correlates with HIF-1alpha Expression FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. May, 2002 | Pubmed ID: 11923216 Copper Ion Redox State is Critical for Its Effects on Ion Transport Pathways and Methaemoglobin Formation in Trout Erythrocytes Chemico-biological Interactions. Jan, 2002 | Pubmed ID: 11803028 Physiologically Low Oxygen Concentrations in Fetal Skin Regulate Hypoxia-inducible Factor 1 and Transforming Growth Factor-beta3 FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Mar, 2002 | Pubmed ID: 11790723 Nitric Oxide Prevents Cardiovascular Disease and Determines Survival in Polyglobulic Mice Overexpressing Erythropoietin Proceedings of the National Academy of Sciences of the United States of America. Oct, 2000 | Pubmed ID: 11027359 Hypoxia-inducible Factor-1 Mediates the Biological Effects of Oxygen on Human Trophoblast Differentiation Through TGFbeta(3) The Journal of Clinical Investigation. Mar, 2000 | Pubmed ID: 10712429 Erythropoietin Modulates Intracellular Calcium in a Human Neuroblastoma Cell Line The Journal of Physiology. Apr, 1999 | Pubmed ID: 10087335 From Genetically Altered Mice to Integrative Physiology News in Physiological Sciences : an International Journal of Physiology Produced Jointly by the International Union of Physiological Sciences and the American Physiological Society. Apr, 1998 | Pubmed ID: 11390761 Cellular and Developmental Control of O2 Homeostasis by Hypoxia-inducible Factor 1 Alpha Genes & Development. Jan, 1998 | Pubmed ID: 9436976 Teknik och patientens urvalskriterierna för höger främre mini torakotomi för Minimal tillgång aortaklaffen ersättning Reza Tavakoli1,2, Pascal Leprince1, Max Gassmann2, Peiman Jamshidi3, Nassrin Yamani4, Julien Amour5, Guillaume Lebreton1 1Department of Cardiovascular and Thoracic Surgery, Pitié Salpêtrière University Hospital, Assistance Publique, Hôpitaux de Paris (APHP), Institut de Cardiologie, 2Institute of Veterinary Physiology and Zurich Center for Integrative Human Physiology, University of Zurich, 3Herzzentrum Hirslanden, Klinik St Anna, 4Department of Radiology, Canton Hospital Lucerne, 5Department of Anesthesiology and Intensive Care Unit, Pitié Salpêtrière University Hospital, Assistance Publique, Hôpitaux de Paris (APHP), Institut de Cardiologie JoVE 57323 Medicine Standardiserad teknik av aortaklaffen förnyad implantation för ventil-sparing Aortic Root ersättare Reza Tavakoli1,2, Guillaume Lebreton1, Max Gassmann2, Peiman Jamshidi3, Pascal Leprince1 1Department of Cardiovascular and Thoracic Surgery, Pitie Salpetriere University Hospital, Assistance Publique, Hopitaux de Paris (APHP), Institut de Cardiologie, 2Institute of Veterinary Physiology and Zurich Center for Integrative Human Physiology, University of Zurich, 3Herzzentrum Hirslanden, Klinik St Anna JoVE 56790 Medicine Teknik av minimalinvasiv tvärgående aorta sammandragning i möss för induktion av vänsterkammarhypertrofi Reza Tavakoli1, Simona Nemska1,2, Peiman Jamshidi3, Max Gassmann1, Nelly Frossard2 1Institute of Veterinary Physiology and Zurich Center for Integrative Human Physiology (ZIHP), University of Zurich, 2Laboratoire d'Innovation Thérapeutique, UMR7200, Université de Strasbourg - CNRS, 3Department of Cardiology, Canton Hospital Lucerne JoVE 56231 Medicine Full-rot Aortic Valve Replacement av stentless Aortic Xenografts hos patienter med små Aortic rötter Reza Tavakoli1,2, Peiman Jamshidi3, Max Gassmann1,2 1Institute of Veterinary Physiology, University of Zurich, 2Zurich Center of Integrative Human Physiology, University of Zurich, 3Department of Cardiology, Canton Hospital Lucerne JoVE 55632 Medicine Direkt Re-implantation av vänstra kransartären in i aorta i Adults med Anomalous ursprung vänstra kransartären från lungartären (ALCAPA) Reza Tavakoli1, Peiman Jamshidi2, Nassrin Yamani3, Max Gassmann1 1Institute of Veterinary Physiology and Zurich Center of Integrative Human Physiology (ZIHP), University of Zurich, 2Department of Cardiology, Canton Hospital Lucerne, 3Department of Radiology, Canton Hospital Lucerne JoVE 55590 Medicine
Teknik och patientens urvalskriterierna för höger främre mini torakotomi för Minimal tillgång aortaklaffen ersättning Reza Tavakoli1,2, Pascal Leprince1, Max Gassmann2, Peiman Jamshidi3, Nassrin Yamani4, Julien Amour5, Guillaume Lebreton1 1Department of Cardiovascular and Thoracic Surgery, Pitié Salpêtrière University Hospital, Assistance Publique, Hôpitaux de Paris (APHP), Institut de Cardiologie, 2Institute of Veterinary Physiology and Zurich Center for Integrative Human Physiology, University of Zurich, 3Herzzentrum Hirslanden, Klinik St Anna, 4Department of Radiology, Canton Hospital Lucerne, 5Department of Anesthesiology and Intensive Care Unit, Pitié Salpêtrière University Hospital, Assistance Publique, Hôpitaux de Paris (APHP), Institut de Cardiologie JoVE 57323 Medicine
Standardiserad teknik av aortaklaffen förnyad implantation för ventil-sparing Aortic Root ersättare Reza Tavakoli1,2, Guillaume Lebreton1, Max Gassmann2, Peiman Jamshidi3, Pascal Leprince1 1Department of Cardiovascular and Thoracic Surgery, Pitie Salpetriere University Hospital, Assistance Publique, Hopitaux de Paris (APHP), Institut de Cardiologie, 2Institute of Veterinary Physiology and Zurich Center for Integrative Human Physiology, University of Zurich, 3Herzzentrum Hirslanden, Klinik St Anna JoVE 56790 Medicine
Teknik av minimalinvasiv tvärgående aorta sammandragning i möss för induktion av vänsterkammarhypertrofi Reza Tavakoli1, Simona Nemska1,2, Peiman Jamshidi3, Max Gassmann1, Nelly Frossard2 1Institute of Veterinary Physiology and Zurich Center for Integrative Human Physiology (ZIHP), University of Zurich, 2Laboratoire d'Innovation Thérapeutique, UMR7200, Université de Strasbourg - CNRS, 3Department of Cardiology, Canton Hospital Lucerne JoVE 56231 Medicine
Full-rot Aortic Valve Replacement av stentless Aortic Xenografts hos patienter med små Aortic rötter Reza Tavakoli1,2, Peiman Jamshidi3, Max Gassmann1,2 1Institute of Veterinary Physiology, University of Zurich, 2Zurich Center of Integrative Human Physiology, University of Zurich, 3Department of Cardiology, Canton Hospital Lucerne JoVE 55632 Medicine
Direkt Re-implantation av vänstra kransartären in i aorta i Adults med Anomalous ursprung vänstra kransartären från lungartären (ALCAPA) Reza Tavakoli1, Peiman Jamshidi2, Nassrin Yamani3, Max Gassmann1 1Institute of Veterinary Physiology and Zurich Center of Integrative Human Physiology (ZIHP), University of Zurich, 2Department of Cardiology, Canton Hospital Lucerne, 3Department of Radiology, Canton Hospital Lucerne JoVE 55590 Medicine
