Nadia L. Mitchell

Publications

• Natural History of Retinal Degeneration in Ovine Models of CLN5 and CLN6 Neuronal Ceroid Lipofuscinoses
  Scientific Reports. 03, 2022  |   Pubmed ID: 35256654
• The Translational Benefits of Sheep As Large Animal Models of Human Neurological Disorders
  Frontiers in Veterinary Science. 2022  |   Pubmed ID: 35242840
• Ocular Therapies for Neuronal Ceroid Lipofuscinoses: More Than Meets the Eye
  Neural Regeneration Research. Aug, 2022  |   Pubmed ID: 35017433
• Electroretinography Data from Ovine Models of CLN5 and CLN6 Neuronal Ceroid Lipofuscinoses
  Data in Brief. Aug, 2021  |   Pubmed ID: 34141843
• Intravitreal Gene Therapy Protects Against Retinal Dysfunction and Degeneration in Sheep with CLN5 Batten Disease
  Experimental Eye Research. 06, 2021  |   Pubmed ID: 33930398
• The Development of Brain Magnetic Resonance Approaches in Large Animal Models for Preclinical Research
  Animal Frontiers : the Review Magazine of Animal Agriculture. Jul, 2019  |   Pubmed ID: 32002261
• Computed Tomography Provides Enhanced Techniques for Longitudinal Monitoring of Progressive Intracranial Volume Loss Associated with Regional Neurodegeneration in Ovine Neuronal Ceroid Lipofuscinoses
  Brain and Behavior. 09, 2018  |   Pubmed ID: 30136763
• Longitudinal In Vivo Monitoring of the CNS Demonstrates the Efficacy of Gene Therapy in a Sheep Model of CLN5 Batten Disease
  Molecular Therapy : the Journal of the American Society of Gene Therapy. 10, 2018  |   Pubmed ID: 30078766
• Practical Implications of Motion Correction with Motion Insensitive Radial K-space Acquisitions in MRI
  The British Journal of Radiology. Jul, 2018  |   Pubmed ID: 29537305
• Characterisation of Early Changes in Ovine CLN5 and CLN6 Batten Disease Neural Cultures for the Rapid Screening of Therapeutics
  Neurobiology of Disease. Apr, 2017  |   Pubmed ID: 28065762
• An EEG Investigation of Sleep Homeostasis in Healthy and CLN5 Batten Disease Affected Sheep
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. 08, 2016  |   Pubmed ID: 27488642
• Molecular Neuropathology of the Synapse in Sheep with CLN5 Batten Disease
  Brain and Behavior. Nov, 2015  |   Pubmed ID: 26664787
• Rapid and Progressive Regional Brain Atrophy in CLN6 Batten Disease Affected Sheep Measured with Longitudinal Magnetic Resonance Imaging
  PloS One. 2015  |   Pubmed ID: 26161747
• Recent Studies of Ovine Neuronal Ceroid Lipofuscinoses from BARN, the Batten Animal Research Network
  Biochimica Et Biophysica Acta. Oct, 2015  |   Pubmed ID: 26073432
• Translational Neurophysiology in Sheep: Measuring Sleep and Neurological Dysfunction in CLN5 Batten Disease Affected Sheep
  Brain : a Journal of Neurology. Apr, 2015  |   Pubmed ID: 25724202
• Inhibition of Storage Pathology in Prenatal CLN5-deficient Sheep Neural Cultures by Lentiviral Gene Therapy
  Neurobiology of Disease. Feb, 2014  |   Pubmed ID: 24269732
• Lentiviral-mediated Gene Transfer to the Sheep Brain: Implications for Gene Therapy in Batten Disease
  Human Gene Therapy. Aug, 2011  |   Pubmed ID: 21595499
• A New Large Animal Model of CLN5 Neuronal Ceroid Lipofuscinosis in Borderdale Sheep is Caused by a Nucleotide Substitution at a Consensus Splice Site (c.571+1G>A) Leading to Excision of Exon 3
  Neurobiology of Disease. Feb, 2008  |   Pubmed ID: 17988881