In JoVE (1)
Articles by Nick Hovenga in JoVE
Treatment of Platelet Products with Riboflavin and UV Light: Effectiveness Against High Titer Bacterial Contamination Shawn D. Keil1, Nick Hovenga1, Denise Gilmour1, Susanne Marschner1, Raymond Goodrich1 1Terumo BCT, Scientific Affairs The storage conditions of platelet products create an ideal environment for bacterial contaminants to multiply to dangerous levels. The goal of this study was to use a colony forming assay to evaluate a riboflavin based pathogen reduction process against high titer bacterial contamination in human platelet products.
Other articles by Nick Hovenga on PubMed
A Laboratory Comparison of Pathogen Reduction Technology Treatment and Culture of Platelet Products for Addressing Bacterial Contamination Concerns Transfusion. Jun, 2009 | Pubmed ID: 19320867 Concerns over the risk of bacterial contamination of platelet products have led to implementation of bacteria culture and other screening methods. New approaches for dealing with this issue have also been proposed.
Inactivation of Viruses in Platelet and Plasma Products Using a Riboflavin-and-UV-based Photochemical Treatment Transfusion. Jul, 2015 | Pubmed ID: 25731607 Multilayered blood safety programs reduce the risk of transfusion-transmitted diseases; however, there remains a risk of window period transmission of screened viruses and transmission of unscreened and emerging viruses from asymptomatic donors. To reduce this risk, a riboflavin-and-UV-light-based pathogen reduction process was evaluated against eight viral agents.