Paul Walther Central Facility for Electron Microscopy Ulm University Biography Publications Institution JoVE Articles Paul Walther has not added a biography. If you are Paul Walther and would like to personalize this page please email our Author Liaison for assistance. Publications Investigation of Modified Nanopore Arrays Using FIB/SEM Tomography Faraday Discussions. Jul, 2018 | Pubmed ID: 29974089 Nutrient Limitation Affects Presynaptic Structures Through Dissociable Bassoon Autophagic Degradation and Impaired Vesicle Release Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 07, 2018 | Pubmed ID: 29972341 Correction: Endonuclease G Promotes Mitochondrial Genome Cleavage and Replication Oncotarget. Jun, 2018 | Pubmed ID: 29963248 Opal-like Multicolor Appearance of Self-Assembled Photonic Array ACS Applied Materials & Interfaces. Jun, 2018 | Pubmed ID: 29842782 Endonuclease G Promotes Mitochondrial Genome Cleavage and Replication Oncotarget. Apr, 2018 | Pubmed ID: 29719607 SAPPβ and SAPPα Increase Structural Complexity and E/I Input Ratio in Primary Hippocampal Neurons and Alter Ca Homeostasis and CREB1-signaling Experimental Neurology. Jun, 2018 | Pubmed ID: 29466703 CHCHD10 Mutations P.R15L and P.G66V Cause Motoneuron Disease by Haploinsufficiency Human Molecular Genetics. Feb, 2018 | Pubmed ID: 29315381 Laser Surface Modification of Decellularized Extracellular Cartilage Matrix for Cartilage Tissue Engineering Lasers in Medical Science. Feb, 2018 | Pubmed ID: 29209868 LC3-associated Phagocytosis in Microbial Pathogenesis International Journal of Medical Microbiology : IJMM. Nov, 2017 | Pubmed ID: 29169848 The Armadillo Protein P0071 Controls KIF3 Motor Transport Journal of Cell Science. Oct, 2017 | Pubmed ID: 28808088 The Cell Polarity Proteins Boi1p and Boi2p Stimulate Vesicle Fusion at the Plasma Membrane of Yeast Cells Journal of Cell Science. Sep, 2017 | Pubmed ID: 28751498 Cellular Mechanism of Fibril Formation from Serum Amyloid A1 Protein EMBO Reports. 08, 2017 | Pubmed ID: 28637682 Vaccinia Virus A11 is Required for Membrane Rupture and Viral Membrane Assembly Cellular Microbiology. 10, 2017 | Pubmed ID: 28618160 Frizzled 3 Acts Upstream of Alcam During Embryonic Eye Development Developmental Biology. 06, 2017 | Pubmed ID: 28427856 Cell-to-cell Transfer of SAA1 Protein in a Cell Culture Model of Systemic AA Amyloidosis Scientific Reports. Mar, 2017 | Pubmed ID: 28361953 Generation and Characterization of Virus-Enhancing Peptide Nanofibrils Functionalized with Fluorescent Labels Bioconjugate Chemistry. 04, 2017 | Pubmed ID: 28300392 Amyloid Plaque Structure and Cell Surface Interactions of β-amyloid Fibrils Revealed by Electron Tomography Scientific Reports. 02, 2017 | Pubmed ID: 28240273 Transient IKK2 Activation in Astrocytes Initiates Selective Non-cell-autonomous Neurodegeneration Molecular Neurodegeneration. 02, 2017 | Pubmed ID: 28193238 A Luciferase Gene Driven by an Alphaherpesviral Promoter Also Responds to Immediate Early Antigens of the Betaherpesvirus HCMV, Allowing Comparative Analyses of Different Human Herpesviruses in One Reporter Cell Line PloS One. 2017 | Pubmed ID: 28060895 Importance of Highly Conserved Peptide Sites of Human Cytomegalovirus GO for Formation of the GH/gL/gO Complex Journal of Virology. Jan, 2017 | Pubmed ID: 27795411 Evaluation of Methods for Pore Generation and Their Influence on Physio-chemical Properties of a Protein Based Hydrogel Biotechnology Reports (Amsterdam, Netherlands). Dec, 2016 | Pubmed ID: 28352549 Metabolic Characterization of Intact Cells Reveals Intracellular Amyloid Beta but Not Its Precursor Protein to Reduce Mitochondrial Respiration PloS One. 2016 | Pubmed ID: 28005987 Fluorescent Nanodiamond-Gold Hybrid Particles for Multimodal Optical and Electron Microscopy Cellular Imaging Nano Letters. Oct, 2016 | Pubmed ID: 27629492 Active Multi-point Microrheology of Cytoskeletal Networks Beilstein Journal of Nanotechnology. 2016 | Pubmed ID: 27335739 A Small Key Unlocks a Heavy Door: The Essential Function of the Small Hydrophobic Proteins SP-B and SP-C to Trigger Adsorption of Pulmonary Surfactant Lamellar Bodies Biochimica Et Biophysica Acta. 08, 2016 | Pubmed ID: 27155084 Electron Tomography Reveals the Fibril Structure and Lipid Interactions in Amyloid Deposits Proceedings of the National Academy of Sciences of the United States of America. May, 2016 | Pubmed ID: 27140609 Branching of Keratin Intermediate Filaments Journal of Structural Biology. 06, 2016 | Pubmed ID: 27039023 Megapinocytosis: a Novel Endocytic Pathway Histochemistry and Cell Biology. Jun, 2016 | Pubmed ID: 26733077 TDP-43 is Intercellularly Transmitted Across Axon Terminals The Journal of Cell Biology. Nov, 2015 | Pubmed ID: 26598621 A New Role for an Old Drug: Ambroxol Triggers Lysosomal Exocytosis Via PH-dependent Ca²⁺ Release from Acidic Ca²⁺ Stores Cell Calcium. Dec, 2015 | Pubmed ID: 26560688 3D Analysis of HCMV Induced-Nuclear Membrane Structures by FIB/SEM Tomography: Insight into an Unprecedented Membrane Morphology Viruses. Nov, 2015 | Pubmed ID: 26556360 Liposomal Delivery of Lipoarabinomannan Triggers Mycobacterium Tuberculosis Specific T-cells Tuberculosis (Edinburgh, Scotland). Jul, 2015 | Pubmed ID: 26043674 Low Dietary Protein Content Alleviates Motor Symptoms in Mice with Mutant Dynactin/dynein-mediated Neurodegeneration Human Molecular Genetics. Apr, 2015 | Pubmed ID: 25552654 Hepcidin Knockout Mice Fed with Iron-rich Diet Develop Chronic Liver Injury and Liver Fibrosis Due to Lysosomal Iron Overload Journal of Hepatology. Sep, 2014 | Pubmed ID: 24816174 Direct Visualization of HIV-enhancing Endogenous Amyloid Fibrils in Human Semen Nature Communications. Apr, 2014 | Pubmed ID: 24691351 Three-dimensional Imaging of Adherent Cells Using FIB/SEM and STEM Methods in Molecular Biology (Clifton, N.J.). 2014 | Pubmed ID: 24357382 Analysis of Nuclear Actin by Overexpression of Wild-type and Actin Mutant Proteins Histochemistry and Cell Biology. Feb, 2014 | Pubmed ID: 24091797 Peptide Nanofibrils Boost Retroviral Gene Transfer and Provide a Rapid Means for Concentrating Viruses Nature Nanotechnology. Feb, 2013 | Pubmed ID: 23334171 Freeze Fracture Approach to Directly Visualize Wetting Transitions on Nanopatterned Superhydrophobic Silicon Surfaces: More Than a Proof of Principle Langmuir : the ACS Journal of Surfaces and Colloids. Jan, 2013 | Pubmed ID: 23259773 Human Cytomegalovirus Infection of M1 and M2 Macrophages Triggers Inflammation and Autologous T-cell Proliferation Journal of Virology. Jan, 2013 | Pubmed ID: 23055571 High-pressure Freezing for Scanning Transmission Electron Tomography Analysis of Cellular Organelles Methods in Molecular Biology (Clifton, N.J.). 2013 | Pubmed ID: 23027022 Three-dimensional Architecture and Biogenesis of Membrane Structures Associated with Hepatitis C Virus Replication PLoS Pathogens. 2012 | Pubmed ID: 23236278 FIB/SEM Tomography with TEM-like Resolution for 3D Imaging of High-pressure Frozen Cells Histochemistry and Cell Biology. Oct, 2012 | Pubmed ID: 22918510 Nuclear Factor κB Activation Impairs Ependymal Ciliogenesis and Links Neuroinflammation to Hydrocephalus Formation The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Aug, 2012 | Pubmed ID: 22915098 Decellularized Cartilage Matrix As a Novel Biomatrix for Cartilage Tissue-engineering Applications Tissue Engineering. Part A. Nov, 2012 | Pubmed ID: 22690787 Sho1p Connects the Plasma Membrane with Proteins of the Cytokinesis Network Through Multiple Isomeric Interaction States Journal of Cell Science. Sep, 2012 | Pubmed ID: 22623719 Peptides Released by Physiological Cleavage of Semen Coagulum Proteins Form Amyloids That Enhance HIV Infection Cell Host & Microbe. Dec, 2011 | Pubmed ID: 22177559 Protein PUL128 of Human Cytomegalovirus is Necessary for Monocyte Infection and Blocking of Migration Journal of Virology. May, 2011 | Pubmed ID: 21367908 The Tegument Protein UL71 of Human Cytomegalovirus is Involved in Late Envelopment and Affects Multivesicular Bodies Journal of Virology. Apr, 2011 | Pubmed ID: 21289123 Preparation of Cryofixed Cells for Improved 3D Ultrastructure with Scanning Transmission Electron Tomography Histochemistry and Cell Biology. Jan, 2011 | Pubmed ID: 21113611 Viral Infection of Cells in Culture--approaches for Electron Microscopy Methods in Cell Biology. 2010 | Pubmed ID: 20869540 Novel Electron Tomographic Methods to Study the Morphology of Keratin Filament Networks Microscopy and Microanalysis : the Official Journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada. Aug, 2010 | Pubmed ID: 20598205 Optimization of STEM Tomography Acquisition--a Comparison of Convergent Beam and Parallel Beam STEM Tomography Ultramicroscopy. Aug, 2010 | Pubmed ID: 20570046 The Effect of Carboxydextran-coated Superparamagnetic Iron Oxide Nanoparticles on C-Jun N-terminal Kinase-mediated Apoptosis in Human Macrophages Biomaterials. Jul, 2010 | Pubmed ID: 20381862 High-resolution Cryo-SEM Allows Direct Identification of F-actin at the Inner Nuclear Membrane of Xenopus Oocytes by Virtue of Its Structural Features Journal of Microscopy. Nov, 2008 | Pubmed ID: 19017237 DM-GRASP/ALCAM/CD166 is Required for Cardiac Morphogenesis and Maintenance of Cardiac Identity in First Heart Field Derived Cells Developmental Biology. Sep, 2008 | Pubmed ID: 18598690 Correlative lys elektronmikroskop (CLEM) for sporing og Imaging Viral Protein forbundet strukturer i Cryo-immobilisert celler Rachel Santarella-Mellwig1, Uta Haselmann2, Nicole L. Schieber1, Paul Walther3, Yannick Schwab1, Claude Antony1, Ralf Bartenschlager2,4, Inés Romero-Brey2 1European Molecular Biology Laboratory, 2Department of Infectious Diseases, Molecular Virology, Heidelberg University, 3Central Facility for Electron Microscopy, Ulm University, 4Heidelberg Partner Site, German Center for Infection Research JoVE 58154 Bioengineering
Correlative lys elektronmikroskop (CLEM) for sporing og Imaging Viral Protein forbundet strukturer i Cryo-immobilisert celler Rachel Santarella-Mellwig1, Uta Haselmann2, Nicole L. Schieber1, Paul Walther3, Yannick Schwab1, Claude Antony1, Ralf Bartenschlager2,4, Inés Romero-Brey2 1European Molecular Biology Laboratory, 2Department of Infectious Diseases, Molecular Virology, Heidelberg University, 3Central Facility for Electron Microscopy, Ulm University, 4Heidelberg Partner Site, German Center for Infection Research JoVE 58154 Bioengineering
