Philip Norris Blood Systems Research Institute Biography Publications Institution JoVE Articles Philip Norris has not added a biography. If you are Philip Norris and would like to personalize this page please email our Author Liaison for assistance. Publications Soluble T Cell Immunoglobulin Mucin Domain 3 Is Shed from CD8+ T Cells by the Sheddase ADAM10, Is Increased in Plasma During Untreated HIV Infection, and Correlates with HIV Disease Progression Journal of Virology. Apr, 2015 | Pubmed ID: 25609823 Recipient Clinical Risk Factors Predominate in Possible Transfusion-related Acute Lung Injury Transfusion. Dec, 2014 | Pubmed ID: 25488517 Downregulation of Cytokines and Chemokines by GB Virus C After Transmission Via Blood Transfusion in HIV-Positive Blood Recipients The Journal of Infectious Diseases. Nov, 2014 | Pubmed ID: 25425697 Role of MicroRNA Modulation in the Interferon-α/ribavirin Suppression of HIV-1 in Vivo PloS One. 2014 | Pubmed ID: 25275557 Albuminuria is Associated with Elevated Acute Phase Reactants and Proinflammatory Markers in HIV-infected Patients Receiving Suppressive Combination Antiretroviral Therapy AIDS Research and Human Retroviruses. Dec, 2014 | Pubmed ID: 25205472 A CD4+ T Cell Antagonist Epitope Down-regulates Activating Signaling Proteins, Up-regulates Inhibitory Signaling Proteins and Abrogates HIV-specific T Cell Function Retrovirology. 2014 | Pubmed ID: 24996903 West Nile Virus Nucleic Acid Persistence in Whole Blood Months After Clearance in Plasma: Implication for Transfusion and Transplantation Safety Transfusion. Dec, 2014 | Pubmed ID: 24965017 Galectin-9 is Rapidly Released During Acute HIV-1 Infection and Remains Sustained at High Levels Despite Viral Suppression Even in Elite Controllers AIDS Research and Human Retroviruses. Jul, 2014 | Pubmed ID: 24786365 Prospective Study on the Clinical Course and Outcomes in Transfusion-related Acute Lung Injury* Critical Care Medicine. Jul, 2014 | Pubmed ID: 24776608 Increased Frequency of Tim-3 Expressing T Cells is Associated with Symptomatic West Nile Virus Infection PloS One. 2014 | Pubmed ID: 24642562 Monocytes Expand with Immune Dysregulation and is Associated with Insulin Resistance in Older Individuals with Chronic HIV PloS One. 2014 | Pubmed ID: 24587328 Reduced CD14 Expression on Classical Monocytes and Vascular Endothelial Adhesion Markers Independently Associate with Carotid Artery Intima Media Thickness in Chronically HIV-1 Infected Adults on Virologically Suppressive Anti-retroviral Therapy Atherosclerosis. Jan, 2014 | Pubmed ID: 24401216 Exosomes from Red Blood Cell Units Bind to Monocytes and Induce Proinflammatory Cytokines, Boosting T-cell Responses in Vitro Blood. Jan, 2014 | Pubmed ID: 24335232 HIV RNA Levels in Plasma and Cervical-vaginal Lavage Fluid in Elite Controllers and HAART Recipients AIDS (London, England). Mar, 2014 | Pubmed ID: 24326356 Cytokine and Chemokine Responses in the Acute Phase of Hepatitis B Virus Replication in Naive and Previously Vaccinated Blood and Plasma Donors The Journal of Infectious Diseases. Mar, 2014 | Pubmed ID: 24158960 Plasma Monocyte Chemoattractant Protein-1 and Tumor Necrosis Factor-α Levels Predict the Presence of Coronary Artery Calcium in HIV-infected Individuals Independent of Traditional Cardiovascular Risk Factors AIDS Research and Human Retroviruses. Feb, 2014 | Pubmed ID: 23984974 In Vitro Measures of Membrane Changes Reveal Differences Between Red Blood Cells Stored in Saline-adenine-glucose-mannitol and AS-1 Additive Solutions: a Paired Study Transfusion. Mar, 2014 | Pubmed ID: 23869602 Leukoreduction and Ultraviolet Treatment Reduce Both the Magnitude and the Duration of the HLA Antibody Response Transfusion. Mar, 2014 | Pubmed ID: 23808544 IL-1Β Enriched Monocytes Mount Massive IL-6 Responses to Common Inflammatory Triggers Among Chronically HIV-1 Infected Adults on Stable Anti-retroviral Therapy at Risk for Cardiovascular Disease PloS One. 2013 | Pubmed ID: 24086545 Fetal Production of Growth Factors and Inflammatory Mediators Predicts Pulmonary Hypertension in Congenital Diaphragmatic Hernia Pediatric Research. Sep, 2013 | Pubmed ID: 23770923 CD57 Expression and Cytokine Production by T Cells in Lesional and Unaffected Skin from Patients with Psoriasis PloS One. 2013 | Pubmed ID: 23468834 Immune Modulation and Lack of Alloimmunization Following Transfusion with Pathogen-reduced Platelets in Mice Transfusion. Mar, 2013 | Pubmed ID: 23451715 Treatment-related Changes in Serum Lipids and Inflammation: Clinical Relevance Remains Unclear. Analyses from the Women's Interagency HIV Study AIDS (London, England). Jun, 2013 | Pubmed ID: 23435295 Low-level HLA Antibodies Do Not Predict Platelet Transfusion Failure in TRAP Study Participants Blood. Apr, 2013 | Pubmed ID: 23393051 Lot-to-lot Variability in HLA Antibody Screening Using a Multiplexed Bead-based Assay Transfusion. Sep, 2013 | Pubmed ID: 23305156 IL-1β Signaling Promotes CNS-intrinsic Immune Control of West Nile Virus Infection PLoS Pathogens. 2012 | Pubmed ID: 23209411 Association of Subclinical Atherosclerosis with Lipid Levels Amongst Antiretroviral-treated and Untreated HIV-infected Women in the Women's Interagency HIV Study Atherosclerosis. Dec, 2012 | Pubmed ID: 23089369 Lower-sensitivity and Avidity Modifications of the Vitros Anti-HIV 1+2 Assay for Detection of Recent HIV Infections and Incidence Estimation Journal of Clinical Microbiology. Dec, 2012 | Pubmed ID: 23035182 Soluble Mediators of Inflammation in HIV and Their Implications for Therapeutics and Vaccine Development Cytokine & Growth Factor Reviews. Aug-Oct, 2012 | Pubmed ID: 22743035 Potential Cardiovascular Disease Risk Markers Among HIV-infected Women Initiating Antiretroviral Treatment Journal of Acquired Immune Deficiency Syndromes (1999). Aug, 2012 | Pubmed ID: 22592585 Detection of Host Immune Responses in Acute Phase Sera of Spontaneous Resolution Versus Persistent Hepatitis C Virus Infection The Journal of General Virology. Aug, 2012 | Pubmed ID: 22535775 Distinct Roles of Trauma and Transfusion in Induction of Immune Modulation After Injury Transfusion. Dec, 2012 | Pubmed ID: 22452342 Sensitive Detection Assays for Influenza RNA Do Not Reveal Viremia in US Blood Donors The Journal of Infectious Diseases. Mar, 2012 | Pubmed ID: 22293429 Expansion of CD8+ T Cells Lacking Sema4D/CD100 During HIV-1 Infection Identifies a Subset of T Cells with Decreased Functional Capacity Blood. Jan, 2012 | Pubmed ID: 22134167 Transfusion-related Acute Lung Injury: Incidence and Risk Factors Blood. Feb, 2012 | Pubmed ID: 22117051 Association Between HLA Class I and Class II Alleles and the Outcome of West Nile Virus Infection: an Exploratory Study PloS One. 2011 | Pubmed ID: 21829673 早期 Post-HIV 抗体陽転期間を識別します。 The Journal of Infectious Diseases. Aug, 2011 | Pubmed ID: 21791654 Multisite Comparison of High-sensitivity Multiplex Cytokine Assays Clinical and Vaccine Immunology : CVI. Aug, 2011 | Pubmed ID: 21697338 Cross-sectional Detection of Acute HIV Infection: Timing of Transmission, Inflammation and Antiretroviral Therapy PloS One. 2011 | Pubmed ID: 21573003 The Effect of HIV Infection and HAART on Inflammatory Biomarkers in a Population-based Cohort of Women AIDS (London, England). Sep, 2011 | Pubmed ID: 21572306 Immune and Genetic Correlates of Vaccine Protection Against Mucosal Infection by SIV in Monkeys Science Translational Medicine. May, 2011 | Pubmed ID: 21543722 [West Nile Virus. II. Immunopathophysiology in Humans] Médecine Sciences : M/S. Apr, 2011 | Pubmed ID: 21524402 [West Nile Virus - I. Conquest of the West] Médecine Sciences : M/S. Apr, 2011 | Pubmed ID: 21524401 Properties of Stored Red Blood Cells: Understanding Immune and Vascular Reactivity Transfusion. Apr, 2011 | Pubmed ID: 21496052 アフェレシス ドナーの HLA 抗体スクリーニング アッセイ ヒューズを確立します。 Transfusion. Oct, 2011 | Pubmed ID: 21332726 A Low T Regulatory Cell Response May Contribute to Both Viral Control and Generalized Immune Activation in HIV Controllers PloS One. 2011 | Pubmed ID: 21305005 Effects of Blood Sample Age at Time of Separation on Measured Cytokine Concentrations in Human Plasma Clinical and Vaccine Immunology : CVI. Feb, 2011 | Pubmed ID: 21159926 HLA 抗体検出アッセイの間で協定はこれまで妊娠中のドナーに高く、コンセンサス カットオフを使用して改善されました。 Transfusion. May, 2011 | Pubmed ID: 21087285 The Frequency and Specificity of Human Neutrophil Antigen Antibodies in a Blood Donor Population Transfusion. Apr, 2011 | Pubmed ID: 20977484 CD57 Defines a Functionally Distinct Population of Mature NK Cells in the Human CD56dimCD16+ NK-cell Subset Blood. Nov, 2010 | Pubmed ID: 20733159 Low-dose Mucosal Simian Immunodeficiency Virus Infection Restricts Early Replication Kinetics and Transmitted Virus Variants in Rhesus Monkeys Journal of Virology. Oct, 2010 | Pubmed ID: 20686016 Evidence of Persistent Low-level Viremia in Long-term HAART-suppressed, HIV-infected Individuals AIDS (London, England). Oct, 2010 | Pubmed ID: 20651585 Human T Cell Leukemia Virus Type 1 Infection Drives Spontaneous Proliferation of Natural Killer Cells Virulence. Jan-Feb, 2010 | Pubmed ID: 20640055 Elevated Caspase-3 Expression and T-cell Activation in Elite Suppressors Journal of Acquired Immune Deficiency Syndromes (1999). May, 2010 | Pubmed ID: 20418727 HIV+ Elite Controllers Have Low HIV-specific T-cell Activation Yet Maintain Strong, Polyfunctional T-cell Responses AIDS (London, England). May, 2010 | Pubmed ID: 20400885 Identification of Specificities of Antibodies Against Human Leukocyte Antigens in Blood Donors Transfusion. Aug, 2010 | Pubmed ID: 20158682 Prevalence of HLA Antibodies in Remotely Transfused or Alloexposed Volunteer Blood Donors Transfusion. Jun, 2010 | Pubmed ID: 20070615 HIV-Selectest Enzyme Immunoassay and Rapid Test: Ability to Detect Seroconversion Following HIV-1 Infection Journal of Clinical Microbiology. Jan, 2010 | Pubmed ID: 19906903 A Novel Human CD4+ T-cell Inducer Subset with Potent Immunostimulatory Properties European Journal of Immunology. Jan, 2010 | Pubmed ID: 19877008 Tregs Control the Development of Symptomatic West Nile Virus Infection in Humans and Mice The Journal of Clinical Investigation. Nov, 2009 | Pubmed ID: 19855131 The Importance of Foxp3 Antibody and Fixation/permeabilization Buffer Combinations in Identifying CD4+CD25+Foxp3+ Regulatory T Cells Cytometry. Part A : the Journal of the International Society for Analytical Cytology. Dec, 2009 | Pubmed ID: 19845018 分泌ドメインへの溶解性顆粒配信の経路を調節するシグナル伝達の初期T細胞受容体の動態 Immunity. Oct, 2009 | Pubmed ID: 19833088 Understanding Loss of Donor White Blood Cell Immunogenicity After Pathogen Reduction: Mechanisms of Action in Ultraviolet Illumination and Riboflavin Treatment Transfusion. Dec, 2009 | Pubmed ID: 19682337 The Effect of Previous Pregnancy and Transfusion on HLA Alloimmunization in Blood Donors: Implications for a Transfusion-related Acute Lung Injury Risk Reduction Strategy Transfusion. Sep, 2009 | Pubmed ID: 19453983 Induction of a Striking Systemic Cytokine Cascade Prior to Peak Viremia in Acute Human Immunodeficiency Virus Type 1 Infection, in Contrast to More Modest and Delayed Responses in Acute Hepatitis B and C Virus Infections Journal of Virology. Apr, 2009 | Pubmed ID: 19176632 Long-term in Vitro Reactivity for Human Leukocyte Antigen Antibodies and Comparison of Detection Using Serum Versus Plasma Transfusion. Feb, 2009 | Pubmed ID: 18980615 Evidence for Persistent Low-level Viremia in Individuals Who Control Human Immunodeficiency Virus in the Absence of Antiretroviral Therapy Journal of Virology. Jan, 2009 | Pubmed ID: 18945778 プロテインキナーゼCシータは、周辺接着リング接合の安定性を調節し、CTLによる標的細胞溶解の感度に貢献 Journal of Immunology (Baltimore, Md. : 1950). Oct, 2008 | Pubmed ID: 18802085 Virus and Antibody Dynamics in Acute West Nile Virus Infection The Journal of Infectious Diseases. Oct, 2008 | Pubmed ID: 18729783 Interferon and Interferon-induced Chemokine Expression is Associated with Control of Acute Viremia in West Nile Virus-infected Blood Donors The Journal of Infectious Diseases. Oct, 2008 | Pubmed ID: 18729779 Suppression of HIV-1 Plasma Viral Load Below Detection Preserves IL-17 Producing T Cells in HIV-1 Infection AIDS (London, England). May, 2008 | Pubmed ID: 18453860 Comprehensive Analysis of West Nile Virus-specific T Cell Responses in Humans The Journal of Infectious Diseases. May, 2008 | Pubmed ID: 18422442 Loss of T Cell Responses Following Long-term Cryopreservation Journal of Immunological Methods. Sep, 2007 | Pubmed ID: 17707394 Nanoparticle-Based Biobarcode Amplification Assay (BCA) for Sensitive and Early Detection of Human Immunodeficiency Type 1 Capsid (p24) Antigen Journal of Acquired Immune Deficiency Syndromes (1999). Oct, 2007 | Pubmed ID: 17693896 Influenza Viremia and the Potential for Blood-borne Transmission Transfusion. Jun, 2007 | Pubmed ID: 17524100 Transfusion-associated Microchimerism: a New Complication of Blood Transfusions in Severely Injured Patients Seminars in Hematology. Jan, 2007 | Pubmed ID: 17198844 Elevations in IL-10, TNF-alpha, and IFN-gamma from the Earliest Point of HIV Type 1 Infection AIDS Research and Human Retroviruses. Aug, 2006 | Pubmed ID: 16910831 CD4のためにP24 HIVに関する抗原決定基+ T細胞を阻害する抗体限定分解、化学修飾、および質量分析により決定される Journal of the American Society for Mass Spectrometry. Nov, 2006 | Pubmed ID: 16875837 The Effects of Early Antiretroviral Therapy and Its Discontinuation on the HIV-specific Antibody Response AIDS Research and Human Retroviruses. Jul, 2006 | Pubmed ID: 16831088 Antagonism of HIV-specific CD4+ T Cells by C-terminal Truncation of a Minimum Epitope Molecular Immunology. Mar, 2006 | Pubmed ID: 16216327 A Hairpin Turn in a Class II MHC-bound Peptide Orients Residues Outside the Binding Groove for T Cell Recognition Proceedings of the National Academy of Sciences of the United States of America. Sep, 2004 | Pubmed ID: 15331779 Beyond Help: Direct Effector Functions of Human Immunodeficiency Virus Type 1-specific CD4(+) T Cells Journal of Virology. Aug, 2004 | Pubmed ID: 15280492 Heat Shock Protein-mediated Cross-presentation of Exogenous HIV Antigen on HLA Class I and Class II Journal of Immunology (Baltimore, Md. : 1950). Aug, 2004 | Pubmed ID: 15265933 Fine Specificity and Cross-clade Reactivity of HIV Type 1 Gag-specific CD4+ T Cells AIDS Research and Human Retroviruses. Mar, 2004 | Pubmed ID: 15117455 Comprehensive Analysis of Human Immunodeficiency Virus Type 1-specific CD4 Responses Reveals Marked Immunodominance of Gag and Nef and the Presence of Broadly Recognized Peptides Journal of Virology. May, 2004 | Pubmed ID: 15078927 Labeling Antigen-specific CD4(+) T Cells with Class II MHC Oligomers Journal of Immunological Methods. Oct, 2002 | Pubmed ID: 12213343 CD4(+) T Helper Cells and the Role They Play in Viral Control Journal of Molecular Medicine (Berlin, Germany). Jul, 2002 | Pubmed ID: 12110945 フローサイトメトリーを用いて細胞外小胞の分析のための技術 Heather Inglis1, Philip Norris1,2,3, Ali Danesh1,3 1Blood Systems Research Institute, 2Department of Medicine, University of California, San Francisco, 3Department of Laboratory Medicine, University of California, San Francisco JoVE 52484 Biology
フローサイトメトリーを用いて細胞外小胞の分析のための技術 Heather Inglis1, Philip Norris1,2,3, Ali Danesh1,3 1Blood Systems Research Institute, 2Department of Medicine, University of California, San Francisco, 3Department of Laboratory Medicine, University of California, San Francisco JoVE 52484 Biology