Pieter S. Hiemstra

Publications

• Smoking Increases Expression of the SARS-CoV-2 Spike Protein-binding Long ACE2 Isoform in Bronchial Epithelium
  Respiratory Research. May, 2023  |   Pubmed ID: 37170105
• Multi-ancestry Genome-wide Association Analyses Improve Resolution of Genes and Pathways Influencing Lung Function and Chronic Obstructive Pulmonary Disease Risk
  Nature Genetics. Mar, 2023  |   Pubmed ID: 36914875
• Th2 High and Mast Cell Gene Signatures Are Associated with Corticosteroid Sensitivity in COPD
  Thorax. Apr, 2023  |   Pubmed ID: 36598042
• Combination of IL-17A/F and TNF-α Uniquely Alters the Bronchial Epithelial Cell Proteome to Enhance Proteins That Augment Neutrophil Migration
  Journal of Inflammation (London, England). Dec, 2022  |   Pubmed ID: 36517803
• SARS-CoV-2-specific CD4 and CD8 T Cell Responses Can Originate from Cross-reactive CMV-specific T Cells
  ELife. Nov, 2022  |   Pubmed ID: 36408799
• Cigarette Smoke Impairs Airway Epithelial Wound Repair: Role of Modulation of Epithelial-Mesenchymal Transition Processes and Notch-1 Signaling
  Antioxidants (Basel, Switzerland). Oct, 2022  |   Pubmed ID: 36290742
• The Lower Airways Microbiota and Antimicrobial Peptides Indicate Dysbiosis in Sarcoidosis
  Microbiome. Oct, 2022  |   Pubmed ID: 36258251
• Early Transcriptional Responses of Bronchial Epithelial Cells to Whole Cigarette Smoke Mirror Those of In-vivo Exposed Human Bronchial Mucosa
  Respiratory Research. Sep, 2022  |   Pubmed ID: 36056356
• Keratin 8 is a Scaffolding and Regulatory Protein of ERAD Complexes
  Cellular and Molecular Life Sciences : CMLS. Sep, 2022  |   Pubmed ID: 36045259
• Association of Bronchial Steroid Inducible Methylation Quantitative Trait Loci with Asthma and Chronic Obstructive Pulmonary Disease Treatment Response
  Clinical and Translational Allergy. Aug, 2022  |   Pubmed ID: 36036237
• Host Succinate Inhibits Influenza Virus Infection Through Succinylation and Nuclear Retention of the Viral Nucleoprotein
  The EMBO Journal. Jun, 2022  |   Pubmed ID: 35506364
• 3D Lung-on-Chip Model Based on Biomimetically Microcurved Culture Membranes
  ACS Biomaterials Science & Engineering. Jun, 2022  |   Pubmed ID: 35502997
• Vitamin D Supplementation in Chronic Obstructive Pulmonary Disease Patients with Low Serum Vitamin D: a Randomized Controlled Trial
  The American Journal of Clinical Nutrition. Aug, 2022  |   Pubmed ID: 35383823
• High MiR203a-3p and MiR-375 Expression in the Airways of Smokers with and Without COPD
  Scientific Reports. Apr, 2022  |   Pubmed ID: 35379844
• Dysregulated Mitochondrial Metabolism Upon Cigarette Smoke Exposure in Various Human Bronchial Epithelial Cell Models
  Disease Models & Mechanisms. Mar, 2022  |   Pubmed ID: 35344036
• Performance of Five Metagenomic Classifiers for Virus Pathogen Detection Using Respiratory Samples from a Clinical Cohort
  Pathogens (Basel, Switzerland). Mar, 2022  |   Pubmed ID: 35335664
• Role of Air Pollutants in Airway Epithelial Barrier Dysfunction in Asthma and COPD
  European Respiratory Review : an Official Journal of the European Respiratory Society. Mar, 2022  |   Pubmed ID: 35321933
• Organoid-based Expansion of Patient-derived Primary Alveolar Type 2 Cells for Establishment of Alveolus Epithelial Lung-Chip Cultures
  American Journal of Physiology. Lung Cellular and Molecular Physiology. Apr, 2022  |   Pubmed ID: 35137633
• Lung Epithelial Cells Interact with Immune Cells and Bacteria to Shape the Microenvironment in Tuberculosis
  Thorax. Apr, 2022  |   Pubmed ID: 35017314
• The Lower Airways Microbiome and Antimicrobial Peptides in Idiopathic Pulmonary Fibrosis Differ from Chronic Obstructive Pulmonary Disease
  PloS One. 2022  |   Pubmed ID: 34990493
• Prolonged Activation of Nasal Immune Cell Populations and Development of Tissue-resident SARS-CoV-2-specific CD8 T Cell Responses Following COVID-19
  Nature Immunology. Jan, 2022  |   Pubmed ID: 34937933
• Determinants of Expression of SARS-CoV-2 Entry-related Genes in Upper and Lower Airways
  Allergy. Feb, 2022  |   Pubmed ID: 34698405
• Novel Insights into Surfactant Protein C Trafficking Revealed Through the Study of a Pathogenic Mutant
  The European Respiratory Journal. Jan, 2022  |   Pubmed ID: 34049951
• Bronchial Gene Expression Signature Associated with Rate of Subsequent FEV Decline in Individuals with and at Risk of COPD
  Thorax. Jan, 2022  |   Pubmed ID: 33972452
• Personalized Pollen Monitoring and Symptom Scores: A Feasibility Study in Grass Pollen Allergic Patients
  Frontiers in Allergy. 2021  |   Pubmed ID: 35387060
• Kallikrein-related Peptidase 5 Contributes to the Remodeling and Repair of Bronchial Epithelium
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Oct, 2021  |   Pubmed ID: 34582061
• Factors Associated with Physical Activity Among COPD Patients with Mild or Moderate Airflow Obstruction
  Monaldi Archives for Chest Disease = Archivio Monaldi Per Le Malattie Del Torace. Sep, 2021  |   Pubmed ID: 34523325
• Disease Modeling Following Organoid-based Expansion of Airway Epithelial Cells
  American Journal of Physiology. Lung Cellular and Molecular Physiology. Oct, 2021  |   Pubmed ID: 34378410
• The Course of AαVal541 As a Proteinase 3 Specific Neo-Epitope After Alpha-1-Antitrypsin Augmentation in Severe Deficient Patients
  International Journal of Molecular Sciences. Jul, 2021  |   Pubmed ID: 34360796
• Comparison of Genome-wide Gene Expression Profiling by RNA Sequencing Microarray in Bronchial Biopsies of COPD Patients Before and After Inhaled Corticosteroid Treatment: Does It Provide New Insights?
  ERJ Open Research. Apr, 2021  |   Pubmed ID: 34164552
• Repairing Damaged Lungs Using Regenerative Therapy
  Current Opinion in Pharmacology. Aug, 2021  |   Pubmed ID: 34161852
• Gender Specific Airway Gene Expression in COPD Sub-phenotypes Supports a Role of Mitochondria and of Different Types of Leukocytes
  Scientific Reports. Jun, 2021  |   Pubmed ID: 34145303
• RAGE and TLR4 Differentially Regulate Airway Hyperresponsiveness: Implications for COPD
  Allergy. Apr, 2021  |   Pubmed ID: 32799375
• A New Portable Sampler to Monitor Pollen at Street Level in the Environment of Patients
  The Science of the Total Environment. Nov, 2020  |   Pubmed ID: 32887011
• An Emerging Class of Air Pollutants: Potential Effects of Microplastics to Respiratory Human Health?
  The Science of the Total Environment. Dec, 2020  |   Pubmed ID: 32827829
• Impact of the Local Inflammatory Environment on Mucosal Vitamin D Metabolism and Signaling in Chronic Inflammatory Lung Diseases
  Frontiers in Immunology. 2020  |   Pubmed ID: 32754156
• Tiotropium and Fluticasone Inhibit Rhinovirus-Induced Mucin Production Via Multiple Mechanisms in Differentiated Airway Epithelial Cells
  Frontiers in Cellular and Infection Microbiology. 2020  |   Pubmed ID: 32637364
• Wnt/β-catenin Signaling is Critical for Regenerative Potential of Distal Lung Epithelial Progenitor Cells in Homeostasis and Emphysema
  Stem Cells (Dayton, Ohio). Nov, 2020  |   Pubmed ID: 32526076
• Suramin Inhibits SARS-CoV-2 Infection in Cell Culture by Interfering with Early Steps of the Replication Cycle
  Antimicrobial Agents and Chemotherapy. Jul, 2020  |   Pubmed ID: 32513797
• Host-microbe Cross-talk in the Lung Microenvironment: Implications for Understanding and Treating Chronic Lung Disease
  The European Respiratory Journal. Aug, 2020  |   Pubmed ID: 32430415
• Vitamin D Deficiency in Asthma and Chronic Obstructive Pulmonary Disease. A Chicken-or-Egg Story
  American Journal of Respiratory and Critical Care Medicine. Aug, 2020  |   Pubmed ID: 32352312
• Adiposity is a Confounding Factor Which Largely Explains the Association of Serum Vitamin D Concentrations with C-reactive Protein, Leptin and Adiponectin
  Cytokine. Jul, 2020  |   Pubmed ID: 32325367
• Short-term and Long-term Effect of a High-intensity Pulmonary Rehabilitation Programme in Obese Patients with Asthma: a Randomised Controlled Trial
  The European Respiratory Journal. Jul, 2020  |   Pubmed ID: 32299852
• Modulation of Airway Epithelial Innate Immunity and Wound Repair by M(GM-CSF) and M(M-CSF) Macrophages
  Journal of Innate Immunity. 2020  |   Pubmed ID: 32289801
• In Vitro Modelling of Alveolar Repair at the Air-liquid Interface Using Alveolar Epithelial Cells Derived from Human Induced Pluripotent Stem Cells
  Scientific Reports. Mar, 2020  |   Pubmed ID: 32218519
• ERS International Congress, Madrid, 2019: Highlights from the Basic and Translational Science Assembly
  ERJ Open Research. Jan, 2020  |   Pubmed ID: 32154289
• Tumor Mutational Load, CD8 T Cells, Expression of PD-L1 and HLA Class I to Guide Immunotherapy Decisions in NSCLC Patients
  Cancer Immunology, Immunotherapy : CII. May, 2020  |   Pubmed ID: 32047958
• Author Correction: Osteopontin Expression in Small Airway Epithelium in Copd is Dependent on Differentiation and Confined to Subsets of Cells
  Scientific Reports. Jan, 2020  |   Pubmed ID: 31937899
• Innate Immunity of the Lung
  Journal of Innate Immunity. 2020  |   Pubmed ID: 31801141
• Mitochondria: at the Crossroads of Regulating Lung Epithelial Cell Function in Chronic Obstructive Pulmonary Disease
  American Journal of Physiology. Lung Cellular and Molecular Physiology. Jan, 2020  |   Pubmed ID: 31693390
• Blood Eosinophil Count and Airway Epithelial Transcriptome Relationships in COPD Versus Asthma
  Allergy. Feb, 2020  |   Pubmed ID: 31506971
• TGF-β1 Impairs Vitamin D-Induced and Constitutive Airway Epithelial Host Defense Mechanisms
  Journal of Innate Immunity. 2020  |   Pubmed ID: 30970352
• Osteopontin Expression in Small Airway Epithelium in Copd is Dependent on Differentiation and Confined to Subsets of Cells
  Scientific Reports. Oct, 2019  |   Pubmed ID: 31664154
• The Respiratory Virome and Exacerbations in Patients with Chronic Obstructive Pulmonary Disease
  PloS One. 2019  |   Pubmed ID: 31647831
• Translation of Findings to Patients with Asthma: a Timely and Compelling Challenge
  The European Respiratory Journal. Oct, 2019  |   Pubmed ID: 31601723
• Perioperative ProADM-change is Associated with the Development of Acute Respiratory Distress Syndrome in Critically Ill Cardiac Surgery Patients: a Prospective Cohort Study
  Biomarkers in Medicine. Sep, 2019  |   Pubmed ID: 31544475
• Sputum Microbiota and Inflammation at Stable State and During Exacerbations in a Cohort of Chronic Obstructive Pulmonary Disease (COPD) Patients
  PloS One. 2019  |   Pubmed ID: 31527888
• Airway and Alveolar Epithelial Cells in Culture
  The European Respiratory Journal. Nov, 2019  |   Pubmed ID: 31515398
• Extract of Helicobacter Pylori Ameliorates Parameters of Airway Inflammation and Goblet Cell Hyperplasia Following Repeated Allergen Exposure
  International Archives of Allergy and Immunology. 2019  |   Pubmed ID: 31242493
• From the Pathophysiology of the Human Lung Alveolus to Epigenetic Editing: Congress 2018 Highlights from ERS Assembly 3 "Basic and Translational Science."
  ERJ Open Research. Apr, 2019  |   Pubmed ID: 31111040
• Macrophage Function in Chronic Obstructive Pulmonary Disease: The Many Faces of Notch Signalling
  EBioMedicine. May, 2019  |   Pubmed ID: 31047859
• Antimicrobial Host Defence Peptides: Immunomodulatory Functions and Translational Prospects
  Advances in Experimental Medicine and Biology. 2019  |   Pubmed ID: 30980358
• TGF-β Activation Impairs Fibroblast Ability to Support Adult Lung Epithelial Progenitor Cell Organoid Formation
  American Journal of Physiology. Lung Cellular and Molecular Physiology. Jul, 2019  |   Pubmed ID: 30969812
• Effect of Long-term Corticosteroid Treatment on MicroRNA and Gene-expression Profiles in COPD
  The European Respiratory Journal. Apr, 2019  |   Pubmed ID: 30846474
• Dynamic Differences in Dietary Polyunsaturated Fatty Acid Metabolism in Sputum of COPD Patients and Controls
  Biochimica Et Biophysica Acta. Molecular and Cell Biology of Lipids. Mar, 2019  |   Pubmed ID: 30528790
• Electronic Cigarettes: a Task Force Report from the European Respiratory Society
  The European Respiratory Journal. Feb, 2019  |   Pubmed ID: 30464018
• Stem Cell-based Lung-on-Chips: The Best of Both Worlds?
  Advanced Drug Delivery Reviews. Feb, 2019  |   Pubmed ID: 30009883
• Air-Liquid Interface Models for Respiratory Toxicology Research: Consensus Workshop and Recommendations
  Applied in Vitro Toxicology. Jun, 2018  |   Pubmed ID: 32953944
• How to Write a Response to the Reviewers of Your Manuscript
  Breathe (Sheffield, England). Dec, 2018  |   Pubmed ID: 30519299
• Retinoic Acid Signaling Balances Adult Distal Lung Epithelial Progenitor Cell Growth and Differentiation
  EBioMedicine. Oct, 2018  |   Pubmed ID: 30236449
• Contribution of Host Defence Proteins and Peptides to Host-Microbiota Interactions in Chronic Inflammatory Lung Diseases
  Vaccines. Jul, 2018  |   Pubmed ID: 30060554
• Immunomodulatory Innate Defence Regulator (IDR) Peptide Alleviates Airway Inflammation and Hyper-responsiveness
  Thorax. Oct, 2018  |   Pubmed ID: 29853649
• Aerobic Exercise Protects from Pseudomonas Aeruginosa-Induced Pneumonia in Elderly Mice
  Journal of Innate Immunity. 2018  |   Pubmed ID: 29843140
• A Novel Method for Expansion and Differentiation of Mouse Tracheal Epithelial Cells in Culture
  Scientific Reports. May, 2018  |   Pubmed ID: 29743551
• Basic and Translational Research in the
  The European Respiratory Journal. May, 2018  |   Pubmed ID: 29724787
• Predictive Value of Eosinophils and Neutrophils on Clinical Effects of ICS in COPD
  Respirology (Carlton, Vic.). Nov, 2018  |   Pubmed ID: 29696728
• Airway Epithelial Cell Function and Respiratory Host Defense in Chronic Obstructive Pulmonary Disease
  Chinese Medical Journal. May, 2018  |   Pubmed ID: 29692382
• Response to Comment on "Therapeutic Application of an Extract of Ameliorates the Development of Allergic Airway Disease"
  Journal of Immunology (Baltimore, Md. : 1950). May, 2018  |   Pubmed ID: 29685947
• Mesenchymal Stromal Cells: a Novel Therapy for the Treatment of Chronic Obstructive Pulmonary Disease?
  Thorax. Jun, 2018  |   Pubmed ID: 29653970
• Aberrant Epithelial Differentiation by Cigarette Smoke Dysregulates Respiratory Host Defence
  The European Respiratory Journal. Apr, 2018  |   Pubmed ID: 29545277
• Effects of E-Cigarette Use on Human Lung Tissue. On Harm Reduction and Causing Harm
  American Journal of Respiratory and Critical Care Medicine. Jul, 2018  |   Pubmed ID: 29518342
• Assembly 3: Basic and Translational Sciences
  Breathe (Sheffield, England). Mar, 2018  |   Pubmed ID: 29515672
• Farm Dust Reduces Viral Load in Human Bronchial Epithelial Cells by Increasing Barrier Function and Antiviral Responses
  The Journal of Allergy and Clinical Immunology. May, 2018  |   Pubmed ID: 29425849
• Effect of Diesel Exhaust Generated by a City Bus Engine on Stress Responses and Innate Immunity in Primary Bronchial Epithelial Cell Cultures
  Toxicology in Vitro : an International Journal Published in Association with BIBRA. Apr, 2018  |   Pubmed ID: 29408669
• Therapeutic Application of an Extract of Ameliorates the Development of Allergic Airway Disease
  Journal of Immunology (Baltimore, Md. : 1950). Mar, 2018  |   Pubmed ID: 29352004
• Associations of Serum 25(OH)D Concentrations with Lung Function, Airway Inflammation and Common Cold in the General Population
  Nutrients. Jan, 2018  |   Pubmed ID: 29301349
• Human Lung Epithelial Cell Cultures for Analysis of Inhaled Toxicants: Lessons Learned and Future Directions
  Toxicology in Vitro : an International Journal Published in Association with BIBRA. Mar, 2018  |   Pubmed ID: 29155131
• Airway Epithelial Barrier Dysfunction in Chronic Obstructive Pulmonary Disease: Role of Cigarette Smoke Exposure
  American Journal of Respiratory Cell and Molecular Biology. Feb, 2018  |   Pubmed ID: 28933915
• Pulmonary Function, Exhaled Nitric Oxide and Symptoms in Asthma Patients with Obesity: a Cross-sectional Study
  Respiratory Research. Dec, 2017  |   Pubmed ID: 29212496
• Reprogramming of Cellular Metabolism: Driver for Airway Remodelling in COPD?
  The European Respiratory Journal. Nov, 2017  |   Pubmed ID: 29191957
• MicroRNA Profiling in Lung Tissue and Bronchoalveolar Lavage of Cigarette Smoke-exposed Mice and in COPD Patients: a Translational Approach
  Scientific Reports. Oct, 2017  |   Pubmed ID: 28993685
• Acute and Chronic Effects of Treatment with Mesenchymal Stromal Cells on LPS-induced Pulmonary Inflammation, Emphysema and Atherosclerosis Development
  PloS One. 2017  |   Pubmed ID: 28910300
• Pre-surgical Pulmonary Rehabilitation in Asthma Patients Undergoing Bariatric Surgery
  Obesity Surgery. Nov, 2017  |   Pubmed ID: 28831733
• The Effects of Selective Hematopoietic Expression of Human IL-37 on Systemic Inflammation and Atherosclerosis in LDLr-Deficient Mice
  International Journal of Molecular Sciences. Aug, 2017  |   Pubmed ID: 28792474
• Bone Morphogenetic Protein 9 Protects Against Neonatal Hyperoxia-Induced Impairment of Alveolarization and Pulmonary Inflammation
  Frontiers in Physiology. 2017  |   Pubmed ID: 28751863
• Cigarette Smoke Differentially Affects IL-13-induced Gene Expression in Human Airway Epithelial Cells
  Physiological Reports. Jul, 2017  |   Pubmed ID: 28701525
• The Effect of Tiotropium in Combination with Olodaterol on House Dust Mite-induced Allergic Airway Disease
  Pulmonary Pharmacology & Therapeutics. Aug, 2017  |   Pubmed ID: 28687462
• Airway Inflammation in COPD After Long-term Withdrawal of Inhaled Corticosteroids
  The European Respiratory Journal. Jun, 2017  |   Pubmed ID: 28619964
• Use of Airway Epithelial Cell Culture to Unravel the Pathogenesis and Study Treatment in Obstructive Airway Diseases
  Pulmonary Pharmacology & Therapeutics. Aug, 2017  |   Pubmed ID: 28502841
• Defining Asthma-COPD Overlap Syndrome: a Population-based Study
  The European Respiratory Journal. May, 2017  |   Pubmed ID: 28461292
• Antimicrobial Peptide Levels Are Linked to Airway Inflammation, Bacterial Colonisation and Exacerbations in Chronic Obstructive Pulmonary Disease
  The European Respiratory Journal. Mar, 2017  |   Pubmed ID: 28298400
• Proinflammatory Cytokines Impair Vitamin D-Induced Host Defense in Cultured Airway Epithelial Cells
  American Journal of Respiratory Cell and Molecular Biology. Jun, 2017  |   Pubmed ID: 28231019
• Antibacterial Defense of Human Airway Epithelial Cells from Chronic Obstructive Pulmonary Disease Patients Induced by Acute Exposure to Nontypeable Haemophilus Influenzae: Modulation by Cigarette Smoke
  Journal of Innate Immunity. 2017  |   Pubmed ID: 28171878
• Diesel Exhaust Alters the Response of Cultured Primary Bronchial Epithelial Cells from Patients with Chronic Obstructive Pulmonary Disease (COPD) to Non-typeable Haemophilus Influenzae
  Respiratory Research. Jan, 2017  |   Pubmed ID: 28129777
• Airway Inflammation in COPD After Long-term Withdrawal of Inhaled Corticosteroids
  The European Respiratory Journal. Jan, 2017  |   Pubmed ID: 28049170
• Xenobiotic Metabolism in Differentiated Human Bronchial Epithelial Cells
  Archives of Toxicology. May, 2017  |   Pubmed ID: 27738743
• Standard Radiotherapy but Not Chemotherapy Impairs Systemic Immunity in Non-small Cell Lung Cancer
  Oncoimmunology. 2016  |   Pubmed ID: 28123900
• Cigarette Smoke Modulates Repair and Innate Immunity Following Injury to Airway Epithelial Cells
  PloS One. 2016  |   Pubmed ID: 27829065
• Functional Characterisation of Bone Marrow-derived Mesenchymal Stromal Cells from COPD Patients
  ERJ Open Research. Apr, 2016  |   Pubmed ID: 27730190
• Basic Science of Electronic Cigarettes: Assessment in Cell Culture and in Vivo Models
  Respiratory Research. 10, 2016  |   Pubmed ID: 27717371
• ADAM17 and EGFR Regulate IL-6 Receptor and Amphiregulin MRNA Expression and Release in Cigarette Smoke-exposed Primary Bronchial Epithelial Cells from Patients with Chronic Obstructive Pulmonary Disease (COPD)
  Physiological Reports. Aug, 2016  |   Pubmed ID: 27561911
• Airway Hyperresponsiveness in Chronic Obstructive Pulmonary Disease: A marker of Asthma-chronic Obstructive Pulmonary Disease Overlap Syndrome?
  The Journal of Allergy and Clinical Immunology. Dec, 2016  |   Pubmed ID: 27345171
• The Dutch National Program for Respiratory Research
  The Lancet. Respiratory Medicine. May, 2016  |   Pubmed ID: 27304557
• Childhood Allergies and Asthma: New Insights on Environmental Exposures and Local Immunity at the Lung Barrier
  Current Opinion in Immunology. Oct, 2016  |   Pubmed ID: 27254380
• Azithromycin Differentially Affects the IL-13-induced Expression Profile in Human Bronchial Epithelial Cells
  Pulmonary Pharmacology & Therapeutics. Aug, 2016  |   Pubmed ID: 27246785
• Lung Function Decline in Asthma Patients with Elevated Bronchial CD8, CD4 and CD3 Cells
  The European Respiratory Journal. Aug, 2016  |   Pubmed ID: 27230446
• Cellular Response of Mucociliary Differentiated Primary Bronchial Epithelial Cells to Diesel Exhaust
  American Journal of Physiology. Lung Cellular and Molecular Physiology. Jul, 2016  |   Pubmed ID: 27190060
• Antimicrobial Peptide P60.4Ac-Containing Creams and Gel for Eradication of Methicillin-Resistant Staphylococcus Aureus from Cultured Skin and Airway Epithelial Surfaces
  Antimicrobial Agents and Chemotherapy. Jul, 2016  |   Pubmed ID: 27114278
• Regeneration of the Lung: Lung Stem Cells and the Development of Lung Mimicking Devices
  Respiratory Research. Apr, 2016  |   Pubmed ID: 27107715
• Neutrophil-derived Alpha Defensins Control Inflammation by Inhibiting Macrophage MRNA Translation
  Proceedings of the National Academy of Sciences of the United States of America. Apr, 2016  |   Pubmed ID: 27044108
• Murine Models of Cardiovascular Comorbidity in Chronic Obstructive Pulmonary Disease
  American Journal of Physiology. Lung Cellular and Molecular Physiology. Jun, 2016  |   Pubmed ID: 26993520
• Microbes and Asthma: Opportunities for Intervention
  The Journal of Allergy and Clinical Immunology. Mar, 2016  |   Pubmed ID: 26947981
• IL-13 and the Airway Epithelium. It Is All in the Genes
  American Journal of Respiratory and Critical Care Medicine. Feb, 2016  |   Pubmed ID: 26871666
• MicroRNA-223 Controls the Expression of Histone Deacetylase 2: a Novel Axis in COPD
  Journal of Molecular Medicine (Berlin, Germany). Jun, 2016  |   Pubmed ID: 26864305
• TNF-α and IL-1β-activated Human Mesenchymal Stromal Cells Increase Airway Epithelial Wound Healing in Vitro Via Activation of the Epidermal Growth Factor Receptor
  Respiratory Research. Jan, 2016  |   Pubmed ID: 26753875
• The Positive Prognostic Effect of Stromal CD8+ Tumor-infiltrating T Cells is Restrained by the Expression of HLA-E in Non-small Cell Lung Carcinoma
  Oncotarget. Jan, 2016  |   Pubmed ID: 26658106
• Antimicrobial Peptides and Innate Lung Defenses: Role in Infectious and Noninfectious Lung Diseases and Therapeutic Applications
  Chest. Feb, 2016  |   Pubmed ID: 26502035
• Regulation of YKL-40 Expression by Corticosteroids: Effect on Pro-inflammatory Macrophages in Vitro and Its Modulation in COPD in Vivo
  Respiratory Research. Dec, 2015  |   Pubmed ID: 26696093
• Prediction of Long-Term Benefits of Inhaled Steroids by Phenotypic Markers in Moderate-to-Severe COPD: A Randomized Controlled Trial
  PloS One. 2015  |   Pubmed ID: 26659582
• Parallel Activities and Interactions Between Antimicrobial Peptides and Complement in Host Defense at the Airway Epithelial Surface
  Molecular Immunology. Nov, 2015  |   Pubmed ID: 26597202
• Nasal Levels of Antimicrobial Peptides in Allergic Asthma Patients and Healthy Controls: Differences and Effect of a Short 1,25(OH)2 Vitamin D3 Treatment
  PloS One. 2015  |   Pubmed ID: 26545199
• Therapeutic Potential of Soluble Guanylate Cyclase Modulators in Neonatal Chronic Lung Disease
  American Journal of Physiology. Lung Cellular and Molecular Physiology. Nov, 2015  |   Pubmed ID: 26432873
• Prevention of Exacerbations in Patients with COPD and Vitamin D Deficiency Through Vitamin D Supplementation (PRECOVID): a Study Protocol
  BMC Pulmonary Medicine. Sep, 2015  |   Pubmed ID: 26399451
• Local and Systemic XAGE-1b-specific Immunity in Patients with Lung Adenocarcinoma
  Cancer Immunology, Immunotherapy : CII. Sep, 2015  |   Pubmed ID: 26025564
• Tiotropium Attenuates IL-13-induced Goblet Cell Metaplasia of Human Airway Epithelial Cells
  Thorax. Jul, 2015  |   Pubmed ID: 25995156
• Effect of Bariatric Surgery on Asthma Control, Lung Function and Bronchial and Systemic Inflammation in Morbidly Obese Subjects with Asthma
  Thorax. Jul, 2015  |   Pubmed ID: 25934136
• Vitamin D, Vitamin D Binding Protein, and Longitudinal Outcomes in COPD
  PloS One. 2015  |   Pubmed ID: 25803709
• Brown Fat Activation Reduces Hypercholesterolaemia and Protects from Atherosclerosis Development
  Nature Communications. Mar, 2015  |   Pubmed ID: 25754609
• Basal Cells Contribute to Innate Immunity of the Airway Epithelium Through Production of the Antimicrobial Protein RNase 7
  Journal of Immunology (Baltimore, Md. : 1950). Apr, 2015  |   Pubmed ID: 25712218
• The Innate Immune Function of Airway Epithelial Cells in Inflammatory Lung Disease
  The European Respiratory Journal. Apr, 2015  |   Pubmed ID: 25700381
• Asthma-COPD Overlap. Clinical Relevance of Genomic Signatures of Type 2 Inflammation in Chronic Obstructive Pulmonary Disease
  American Journal of Respiratory and Critical Care Medicine. Apr, 2015  |   Pubmed ID: 25611785
• Genome-Wide Association Study Identification of Novel Loci Associated with Airway Responsiveness in Chronic Obstructive Pulmonary Disease
  American Journal of Respiratory Cell and Molecular Biology. Aug, 2015  |   Pubmed ID: 25514360
• Brown Adipose Tissue Takes Up Plasma Triglycerides Mostly After Lipolysis
  Journal of Lipid Research. Jan, 2015  |   Pubmed ID: 25351615
• Function of Monocytes and Monocyte-derived Macrophages in α1-antitrypsin Deficiency
  The European Respiratory Journal. Feb, 2015  |   Pubmed ID: 25323228
• Dissecting the Genetics of Chronic Mucus Hypersecretion in Smokers with and Without COPD
  The European Respiratory Journal. Jan, 2015  |   Pubmed ID: 25234806
• Efficient and Sensitive Identification and Quantification of Airborne Pollen Using Next-generation DNA Sequencing
  Molecular Ecology Resources. Jan, 2015  |   Pubmed ID: 24893805
• Muscarinic M3 Receptors on Structural Cells Regulate Cigarette Smoke-induced Neutrophilic Airway Inflammation in Mice
  American Journal of Physiology. Lung Cellular and Molecular Physiology. Nov, 2014  |   Pubmed ID: 25381025
• Reproducibility of Exhaled Nitric Oxide Measurements in Overweight and Obese Adults
  BMC Research Notes. Nov, 2014  |   Pubmed ID: 25366981
• Club Cells, CC10 and Self-control at the Epithelial Surface
  The European Respiratory Journal. Oct, 2014  |   Pubmed ID: 25271220
• Genome-wide Association Analysis Identifies Six New Loci Associated with Forced Vital Capacity
  Nature Genetics. Jul, 2014  |   Pubmed ID: 24929828
• LL-37-derived Peptides Eradicate Multidrug-resistant Staphylococcus Aureus from Thermally Wounded Human Skin Equivalents
  Antimicrobial Agents and Chemotherapy. Aug, 2014  |   Pubmed ID: 24841266
• Susceptibility to Chronic Mucus Hypersecretion, a Genome Wide Association Study
  PloS One. 2014  |   Pubmed ID: 24714607
• Steroid Resistance in COPD? Overlap and Differential Anti-inflammatory Effects in Smokers and Ex-smokers
  PloS One. 2014  |   Pubmed ID: 24505290
• Recent Progress in Peptide Vaccination in Cancer with a Focus on Non-small-cell Lung Cancer
  Expert Review of Vaccines. Jan, 2014  |   Pubmed ID: 24308580
• Increased ERK Signalling Promotes Inflammatory Signalling in Primary Airway Epithelial Cells Expressing Z α1-antitrypsin
  Human Molecular Genetics. Feb, 2014  |   Pubmed ID: 24097797
• Airway Gene Expression in COPD is Dynamic with Inhaled Corticosteroid Treatment and Reflects Biological Pathways Associated with Disease Activity
  Thorax. Jan, 2014  |   Pubmed ID: 23925644
• Development and Validation of a 5-day-ahead Hay Fever Forecast for Patients with Grass-pollen-induced Allergic Rhinitis
  International Journal of Biometeorology. Aug, 2014  |   Pubmed ID: 23780494
• PH in Exhaled Breath Condensate and Nasal Lavage As a Biomarker of Air Pollution-related Inflammation in Street Traffic-controllers and Office-workers
  Clinics (Sao Paulo, Brazil). Dec, 2013  |   Pubmed ID: 24473505
• The Effect of PPE-induced Emphysema and Chronic LPS-induced Pulmonary Inflammation on Atherosclerosis Development in APOE*3-LEIDEN Mice
  PloS One. 2013  |   Pubmed ID: 24303000
• Increase in Net Activity of Serine Proteinases but Not Gelatinases After Local Endotoxin Exposure in the Peripheral Airways of Healthy Subjects
  PloS One. 2013  |   Pubmed ID: 24086430
• Development of a Nose Cream Containing the Synthetic Antimicrobial Peptide P60.4Ac for Eradication of Methicillin-resistant Staphylococcus Aureus Carriage
  Journal of Pharmaceutical Sciences. Oct, 2013  |   Pubmed ID: 23955373
• Inhaled Steroids Modulate Extracellular Matrix Composition in Bronchial Biopsies of COPD Patients: a Randomized, Controlled Trial
  PloS One. 2013  |   Pubmed ID: 23667615
• CD8(+) T Cells Characterize Early Smoking-related Airway Pathology in Patients with Asthma
  Respiratory Medicine. Jul, 2013  |   Pubmed ID: 23639272
• Systemic Inflammation and Lung Function Impairment in Morbidly Obese Subjects with the Metabolic Syndrome
  Journal of Obesity. 2013  |   Pubmed ID: 23509614
• Resveratrol Protects Against Atherosclerosis, but Does Not Add to the Antiatherogenic Effect of Atorvastatin, in APOE*3-Leiden.CETP Mice
  The Journal of Nutritional Biochemistry. Aug, 2013  |   Pubmed ID: 23337345
• Profiling the Proteome of Exhaled Breath Condensate in Healthy Smokers and COPD Patients by LC-MS/MS
  International Journal of Molecular Sciences. Oct, 2012  |   Pubmed ID: 23203040
• Toll-like Receptor (TLR2 and TLR4) Polymorphisms and Chronic Obstructive Pulmonary Disease
  PloS One. 2012  |   Pubmed ID: 22952638
• α1-antitrypsin Production by Proinflammatory and Antiinflammatory Macrophages and Dendritic Cells
  American Journal of Respiratory Cell and Molecular Biology. May, 2012  |   Pubmed ID: 22162908
• A Quantitative Method for Detection of Spliced X-box Binding Protein-1 (XBP1) MRNA As a Measure of Endoplasmic Reticulum (ER) Stress
  Cell Stress & Chaperones. Mar, 2012  |   Pubmed ID: 22038282
• Hepatocyte-specific IKKβ Expression Aggravates Atherosclerosis Development in APOE*3-Leiden Mice
  Atherosclerosis. Feb, 2012  |   Pubmed ID: 21798539
• Difference in Symptom Severity Between Early and Late Grass Pollen Season in Patients with Seasonal Allergic Rhinitis
  Clinical and Translational Allergy. Dec, 2011  |   Pubmed ID: 22410160
• PRAME-specific Allo-HLA-restricted T Cells with Potent Antitumor Reactivity Useful for Therapeutic T-cell Receptor Gene Transfer
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Sep, 2011  |   Pubmed ID: 21771875
• IL-4 and IL-13 Exposure During Mucociliary Differentiation of Bronchial Epithelial Cells Increases Antimicrobial Activity and Expression of Antimicrobial Peptides
  Respiratory Research. May, 2011  |   Pubmed ID: 21529380
• Smoking Status and Anti-inflammatory Macrophages in Bronchoalveolar Lavage and Induced Sputum in COPD
  Respiratory Research. Mar, 2011  |   Pubmed ID: 21426578
• The Role of IREB2 and Transforming Growth Factor Beta-1 Genetic Variants in COPD: a Replication Case-control Study
  BMC Medical Genetics. Feb, 2011  |   Pubmed ID: 21320324
• Severe Congenital Neutropenia in a Multigenerational Family with a Novel Neutrophil Elastase (ELANE) Mutation
  Annals of Hematology. Feb, 2011  |   Pubmed ID: 20803142
• Pro-inflammatory Mechanisms of Muscarinic Receptor Stimulation in Airway Smooth Muscle
  Respiratory Research. Sep, 2010  |   Pubmed ID: 20875145
• LL-37 Directs Macrophage Differentiation Toward Macrophages with a Proinflammatory Signature
  Journal of Immunology (Baltimore, Md. : 1950). Aug, 2010  |   Pubmed ID: 20610648
• Multidrug Resistance-associated Protein-1 (MRP1) Genetic Variants, MRP1 Protein Levels and Severity of COPD
  Respiratory Research. May, 2010  |   Pubmed ID: 20487524
• Recent Advances in Alveolar Biology: Evolution and Function of Alveolar Proteins
  Respiratory Physiology & Neurobiology. Aug, 2010  |   Pubmed ID: 20433956
• Expression Patterns of Protein C Inhibitor in Mouse Development
  Journal of Molecular Histology. Feb, 2010  |   Pubmed ID: 20229239
• Association of MMP-2 Polymorphisms with Severe and Very Severe COPD: a Case Control Study of MMPs-1, 9 and 12 in a European Population
  BMC Medical Genetics. Jan, 2010  |   Pubmed ID: 20078883
• Effect of Fluticasone with and Without Salmeterol on Pulmonary Outcomes in Chronic Obstructive Pulmonary Disease: a Randomized Trial
  Annals of Internal Medicine. Oct, 2009  |   Pubmed ID: 19841453
• Comparison of Exhaled Breath Condensate PH Using Two Commercially Available Devices in Healthy Controls, Asthma and COPD Patients
  Respiratory Research. Aug, 2009  |   Pubmed ID: 19703285
• Expression of Smooth Muscle and Extracellular Matrix Proteins in Relation to Airway Function in Asthma
  The Journal of Allergy and Clinical Immunology. May, 2008  |   Pubmed ID: 18405955
• An Antimicrobial Peptide Modulates Epithelial Responses to Bacterial Products
  The Laryngoscope. May, 2008  |   Pubmed ID: 18300705
• The Role of Epithelial Beta-defensins and Cathelicidins in Host Defense of the Lung
  Experimental Lung Research. Dec, 2007  |   Pubmed ID: 18075828
• Reduction in Sputum Neutrophil and Eosinophil Numbers by the PDE4 Inhibitor Roflumilast in Patients with COPD
  Thorax. Dec, 2007  |   Pubmed ID: 17573446
• Human Neutrophil Peptide-1 Inhibits Both the Classical and the Lectin Pathway of Complement Activation
  Molecular Immunology. Jul, 2007  |   Pubmed ID: 17448537
• Inhaled Nitric Oxide Attenuates Pulmonary Inflammation and Fibrin Deposition and Prolongs Survival in Neonatal Hyperoxic Lung Injury
  American Journal of Physiology. Lung Cellular and Molecular Physiology. Jul, 2007  |   Pubmed ID: 17384081
• Bronchial Inflammation and Airway Responses to Deep Inspiration in Asthma and Chronic Obstructive Pulmonary Disease
  American Journal of Respiratory and Critical Care Medicine. Jul, 2007  |   Pubmed ID: 17379851
• Demonstration of Bacterial Cells and Glycocalyx in Biofilms on Human Tonsils
  Archives of Otolaryngology--head & Neck Surgery. Feb, 2007  |   Pubmed ID: 17309977
• Small Airways Dysfunction and Neutrophilic Inflammation in Bronchial Biopsies and BAL in COPD
  Chest. Jan, 2007  |   Pubmed ID: 17218556
• Exploring Host-pathogen Interactions at the Epithelial Surface: Application of Transcriptomics in Lung Biology
  American Journal of Physiology. Lung Cellular and Molecular Physiology. Feb, 2007  |   Pubmed ID: 17041013
• Epithelial Differentiation is a Determinant in the Production of Eotaxin-2 and -3 by Bronchial Epithelial Cells in Response to IL-4 and IL-13
  Molecular Immunology. Feb, 2007  |   Pubmed ID: 16740309
• Adenovirus-specific CD4+ T Cell Clones Recognizing Endogenous Antigen Inhibit Viral Replication in Vitro Through Cognate Interaction
  Journal of Immunology (Baltimore, Md. : 1950). Dec, 2006  |   Pubmed ID: 17142788
• The SERPINE2 Gene and Chronic Obstructive Pulmonary Disease
  American Journal of Human Genetics. Jul, 2006  |   Pubmed ID: 16773582
• The Antimicrobial Peptide LL-37 Enhances IL-8 Release by Human Airway Smooth Muscle Cells
  The Journal of Allergy and Clinical Immunology. Jun, 2006  |   Pubmed ID: 16750994
• Human Cathelicidin LL-37 is a Chemoattractant for Eosinophils and Neutrophils That Acts Via Formyl-peptide Receptors
  International Archives of Allergy and Immunology. 2006  |   Pubmed ID: 16557028
• A Molecular Signature of Epithelial Host Defense: Comparative Gene Expression Analysis of Cultured Bronchial Epithelial Cells and Keratinocytes
  BMC Genomics. Jan, 2006  |   Pubmed ID: 16420688
• Expression of Epidermal Growth Factors and Their Receptors in the Bronchial Epithelium of Subjects with Chronic Obstructive Pulmonary Disease
  American Journal of Clinical Pathology. Feb, 2006  |   Pubmed ID: 16393673
• Development of Novel LL-37 Derived Antimicrobial Peptides with LPS and LTA Neutralizing and Antimicrobial Activities for Therapeutic Application
  Peptides. Apr, 2006  |   Pubmed ID: 16274847
• Cytokine-dependent Proliferation of Human CD34+ Progenitor Cells in the Absence of Serum is Suppressed by Their Progeny's Production of Serine Proteinases
  Stem Cells (Dayton, Ohio). Feb, 2006  |   Pubmed ID: 16109763
• Effects of Cigarette Smoke Condensate on Proliferation and Wound Closure of Bronchial Epithelial Cells in Vitro: Role of Glutathione
  Respiratory Research. Nov, 2005  |   Pubmed ID: 16309548
• Bronchial CD8 Cell Infiltrate and Lung Function Decline in Asthma
  American Journal of Respiratory and Critical Care Medicine. Oct, 2005  |   Pubmed ID: 16085937
• Host Defense Effector Molecules in Mucosal Secretions
  FEMS Immunology and Medical Microbiology. Aug, 2005  |   Pubmed ID: 16051067
• The Human Cathelicidin LL-37: a Multifunctional Peptide Involved in Infection and Inflammation in the Lung
  Pulmonary Pharmacology & Therapeutics. 2005  |   Pubmed ID: 15939310
• Eotaxin-2 and Eotaxin-3 Expression is Associated with Persistent Eosinophilic Bronchial Inflammation in Patients with Asthma After Allergen Challenge
  The Journal of Allergy and Clinical Immunology. Apr, 2005  |   Pubmed ID: 15805998
• Transcriptional Response of Bronchial Epithelial Cells to Pseudomonas Aeruginosa: Identification of Early Mediators of Host Defense
  Physiological Genomics. May, 2005  |   Pubmed ID: 15701729
• Interactions Between Neutrophil-derived Antimicrobial Peptides and Airway Epithelial Cells
  Journal of Leukocyte Biology. Apr, 2005  |   Pubmed ID: 15591123
• TGF-beta Differentially Regulates TH2 Cytokine-induced Eotaxin and Eotaxin-3 Release by Human Airway Smooth Muscle Cells
  The Journal of Allergy and Clinical Immunology. Oct, 2004  |   Pubmed ID: 15480317
• Bacterial Products Increase Expression of the Human Cathelicidin HCAP-18/LL-37 in Cultured Human Sinus Epithelial Cells
  FEMS Immunology and Medical Microbiology. Oct, 2004  |   Pubmed ID: 15364108
• Gene Expression Profile and Histopathology of Experimental Bronchopulmonary Dysplasia Induced by Prolonged Oxidative Stress
  Free Radical Biology & Medicine. Mar, 2004  |   Pubmed ID: 14990357
• Series Introduction: Innate Host Defense of the Respiratory Epithelium
  Journal of Leukocyte Biology. Jan, 2004  |   Pubmed ID: 14612432
• Neutrophil Defensins Enhance Lung Epithelial Wound Closure and Mucin Gene Expression in Vitro
  American Journal of Respiratory Cell and Molecular Biology. Feb, 2004  |   Pubmed ID: 12871849
• The Antimicrobial Peptide LL-37 Activates Innate Immunity at the Airway Epithelial Surface by Transactivation of the Epidermal Growth Factor Receptor
  Journal of Immunology (Baltimore, Md. : 1950). Dec, 2003  |   Pubmed ID: 14662872
• Rhinovirus Increases Human Beta-defensin-2 and -3 MRNA Expression in Cultured Bronchial Epithelial Cells
  FEMS Immunology and Medical Microbiology. Aug, 2003  |   Pubmed ID: 12900056
• Are Rhinovirus-induced Airway Responses in Asthma Aggravated by Chronic Allergen Exposure?
  American Journal of Respiratory and Critical Care Medicine. Nov, 2003  |   Pubmed ID: 12893645
• An Angiogenic Role for the Human Peptide Antibiotic LL-37/hCAP-18
  The Journal of Clinical Investigation. Jun, 2003  |   Pubmed ID: 12782669
• Expression of Beta-defensin 1 and 2 MRNA by Human Monocytes, Macrophages and Dendritic Cells
  Immunology. Aug, 2002  |   Pubmed ID: 12153515
• World Congress on Lung Health and 10th ERS Annual Congress 30 August-3 September 2000, Florence, Italy
  Respiratory Research. 2000  |   Pubmed ID: 11667983