Ralph Weissleder Center for Systems Biology Massachusetts General Hospital Biography Publications Institution JoVE Articles Ralph Weissleder has not added a biography. If you are Ralph Weissleder and would like to personalize this page please email our Author Liaison for assistance. Publications Bioorthogonal Approach to Identify Unsuspected Drug Targets in Live Cells Angewandte Chemie (International Ed. in English). Aug, 2013 | Pubmed ID: 23960025 Local Proliferation Dominates Lesional Macrophage Accumulation in Atherosclerosis Nature Medicine. Sep, 2013 | Pubmed ID: 23933982 Miniaturized Nuclear Magnetic Resonance Platform for Detection and Profiling of Circulating Tumor Cells Lab on a Chip. Jul, 2013 | Pubmed ID: 23835814 Targeting Cathepsin E in Pancreatic Cancer by a Small Molecule Allows in Vivo Detection Neoplasia (New York, N.Y.). Jul, 2013 | Pubmed ID: 23814481 Nanoparticle PET-CT Detects Rejection and Immunomodulation in Cardiac Allografts Circulation. Cardiovascular Imaging. Jul, 2013 | Pubmed ID: 23771986 BODIPY-tetrazine Derivatives As Superbright Bioorthogonal Turn-on Probes Angewandte Chemie (International Ed. in English). Jul, 2013 | Pubmed ID: 23712730 A Pretargeted PET Imaging Strategy Based on Bioorthogonal Diels-Alder Click Chemistry Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Aug, 2013 | Pubmed ID: 23708196 A Magneto-DNA Nanoparticle System for Rapid Detection and Phenotyping of Bacteria Nature Nanotechnology. May, 2013 | Pubmed ID: 23644570 Monocyte-directed RNAi Targeting CCR2 Improves Infarct Healing in Atherosclerosis-prone Mice Circulation. May, 2013 | Pubmed ID: 23616627 Magnetic Barcode Assay for Genetic Detection of Pathogens Nature Communications. 2013 | Pubmed ID: 23612293 Upconverting Organic Dye Doped Core-shell Nano-composites for Dual-modality NIR Imaging and Photo-thermal Therapy Theranostics. 2013 | Pubmed ID: 23606913 Single Cell Analysis of Drug Distribution by Intravital Imaging PloS One. 2013 | Pubmed ID: 23593370 Fluorescence Endoscopy of Cathepsin Activity Discriminates Dysplasia from Colitis Inflammatory Bowel Diseases. Jun, 2013 | Pubmed ID: 23591598 Comparison of Select Cancer Biomarkers in Human Circulating and Bulk Tumor Cells Using Magnetic Nanoparticles and a Miniaturized Micro-NMR System Nanomedicine : Nanotechnology, Biology, and Medicine. Apr, 2013 | Pubmed ID: 23570873 μHall Chip for Sensitive Detection of Bacteria Advanced Healthcare Materials. Sep, 2013 | Pubmed ID: 23495188 Nano-SAR Development for Bioactivity of Nanoparticles with Considerations of Decision Boundaries Small (Weinheim an Der Bergstrasse, Germany). May, 2013 | Pubmed ID: 23423856 单个细胞和亚细胞的药代动力学成像允许毒品行动深入体内。 Nature Communications. 2013 | Pubmed ID: 23422672 血管紧张素 II 驱动器生产的肿瘤促进巨噬细胞。 Immunity. Jan, 2013 | Pubmed ID: 23333075 Polymeric Nanoparticle PET/MR Imaging Allows Macrophage Detection in Atherosclerotic Plaques Circulation Research. Mar, 2013 | Pubmed ID: 23300273 Dual Imaging and Photoactivated Nanoprobe for Controlled Cell Tracking Small (Weinheim an Der Bergstrasse, Germany). Jan, 2013 | Pubmed ID: 22996932 Noise Suppressed, Multifocus Image Fusion for Enhanced Intraoperative Navigation Journal of Biophotonics. Apr, 2013 | Pubmed ID: 22887724 Efficient (18)F-Labeling of Synthetic Exendin-4 Analogues for Imaging Beta Cells ChemistryOpen. Aug, 2012 | Pubmed ID: 23997998 Systemic RNAi-mediated Gene Silencing in Nonhuman Primate and Rodent Myeloid Cells Molecular Therapy. Nucleic Acids. 2012 | Pubmed ID: 23344621 Painting Blood Vessels and Atherosclerotic Plaques with an Adhesive Drug Depot Proceedings of the National Academy of Sciences of the United States of America. Dec, 2012 | Pubmed ID: 23236189 The Histone Deacetylase SIRT6 is a Tumor Suppressor That Controls Cancer Metabolism Cell. Dec, 2012 | Pubmed ID: 23217706 Microfluidic Cell Sorter (μFCS) for On-chip Capture and Analysis of Single Cells Advanced Healthcare Materials. Jul, 2012 | Pubmed ID: 23184773 Selective Factor XIIa Inhibition Attenuates Silent Brain Ischemia: Application of Molecular Imaging Targeting Coagulation Pathway JACC. Cardiovascular Imaging. Nov, 2012 | Pubmed ID: 23153913 Implantable Microenvironments to Attract Hematopoietic Stem/cancer Cells Proceedings of the National Academy of Sciences of the United States of America. Nov, 2012 | Pubmed ID: 23150542 Protein Typing of Circulating Microvesicles Allows Real-time Monitoring of Glioblastoma Therapy Nature Medicine. Dec, 2012 | Pubmed ID: 23142818 Photocleavable DNA Barcode-antibody Conjugates Allow Sensitive and Multiplexed Protein Analysis in Single Cells Journal of the American Chemical Society. Nov, 2012 | Pubmed ID: 23092113 Improved Intravital Microscopy Via Synchronization of Respiration and Holder Stabilization Journal of Biomedical Optics. Sep, 2012 | Pubmed ID: 23085919 Modeling Biological Activities of Nanoparticles Nano Letters. Nov, 2012 | Pubmed ID: 23039907 Inflammation Modulates Murine Venous Thrombosis Resolution in Vivo: Assessment by Multimodal Fluorescence Molecular Imaging Arteriosclerosis, Thrombosis, and Vascular Biology. Nov, 2012 | Pubmed ID: 22995524 Real-time in Vivo Imaging of the Beating Mouse Heart at Microscopic Resolution Nature Communications. 2012 | Pubmed ID: 22968700 Optochemogenetics (OCG) Allows More Precise Control of Genetic Engineering in Mice with CreER Regulators Bioconjugate Chemistry. Sep, 2012 | Pubmed ID: 22917215 CT322, a VEGFR-2 Antagonist, Demonstrates Anti-glioma Efficacy in Orthotopic Brain Tumor Model As a Single Agent or in Combination with Temozolomide and Radiation Therapy Journal of Neuro-oncology. Oct, 2012 | Pubmed ID: 22875706 Ultrasensitive Clinical Enumeration of Rare Cells Ex Vivo Using a Micro-hall Detector Science Translational Medicine. Jul, 2012 | Pubmed ID: 22764208 Myocardial Infarction Accelerates Atherosclerosis Nature. Jul, 2012 | Pubmed ID: 22763456 Mechanism of Magnetic Relaxation Switching Sensing ACS Nano. Aug, 2012 | Pubmed ID: 22762250 Sensitive and Direct Detection of Circulating Tumor Cells by Multimarker µ-nuclear Magnetic Resonance Neoplasia (New York, N.Y.). May, 2012 | Pubmed ID: 22745585 A Magnetic Gram Stain for Bacterial Detection Angewandte Chemie (International Ed. in English). Jul, 2012 | Pubmed ID: 22744868 Notch Ligand Delta-like 4 Blockade Attenuates Atherosclerosis and Metabolic Disorders Proceedings of the National Academy of Sciences of the United States of America. Jul, 2012 | Pubmed ID: 22699504 分子影像学的使用有针对性的纤维蛋白近红外荧光的深静脉血栓形成的纤维蛋白沉积。 JACC. Cardiovascular Imaging. Jun, 2012 | Pubmed ID: 22698530 Bioorthogonal Imaging of Aurora Kinase A in Live Cells Angewandte Chemie (International Ed. in English). Jul, 2012 | Pubmed ID: 22644700 Regulation of Monocyte Functional Heterogeneity by MiR-146a and Relb Cell Reports. Apr, 2012 | Pubmed ID: 22545247 Oncogenic Kras Maintains Pancreatic Tumors Through Regulation of Anabolic Glucose Metabolism Cell. Apr, 2012 | Pubmed ID: 22541435 Mapping Molecular Agents Distributions in Whole Mice Hearts Using Born-normalized Optical Projection Tomography PloS One. 2012 | Pubmed ID: 22509302 In Vivo Imaging of Drug-induced Mitochondrial Outer Membrane Permeabilization at Single-cell Resolution Cancer Research. Jun, 2012 | Pubmed ID: 22505651 Establishment and Characterization of a Novel Chordoma Cell Line: CH22 Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. Oct, 2012 | Pubmed ID: 22504929 Imaging Therapeutic PARP Inhibition in Vivo Through Bioorthogonally Developed Companion Imaging Agents Neoplasia (New York, N.Y.). Mar, 2012 | Pubmed ID: 22496617 Synthesis of [18F]BODIPY: Bifunctional Reporter for Hybrid Optical/positron Emission Tomography Imaging Angewandte Chemie (International Ed. in English). May, 2012 | Pubmed ID: 22473535 Demyelinating Diseases: Myeloperoxidase As an Imaging Biomarker and Therapeutic Target Radiology. May, 2012 | Pubmed ID: 22438365 Orthogonal Amplification of Nanoparticles for Improved Diagnostic Sensing ACS Nano. Apr, 2012 | Pubmed ID: 22424443 Reactive Polymer Enables Efficient in Vivo Bioorthogonal Chemistry Proceedings of the National Academy of Sciences of the United States of America. Mar, 2012 | Pubmed ID: 22411831 Single Reporter for Targeted Multimodal in Vivo Imaging Journal of the American Chemical Society. Mar, 2012 | Pubmed ID: 22397453 Early Window of Diabetes Determinism in NOD Mice, Dependent on the Complement Receptor CRIg, Identified by Noninvasive Imaging Nature Immunology. Apr, 2012 | Pubmed ID: 22366893 Multifunctional Nanoagent for Thrombus-targeted Fibrinolytic Therapy Nanomedicine (London, England). Jul, 2012 | Pubmed ID: 22348271 神经肽 Neuromedin U 促进自身抗体介导的关节炎。 Arthritis Research & Therapy. Feb, 2012 | Pubmed ID: 22314006 肿瘤相关巨噬细胞和嗜中性粒细胞的起源。 Proceedings of the National Academy of Sciences of the United States of America. Feb, 2012 | Pubmed ID: 22308361 磁性纳米粒子和 MicroNMR 用于诊断应用程序。 Theranostics. 2012 | Pubmed ID: 22272219 天然免疫反应激活 B 细胞抵御微生物脓毒症。 Science (New York, N.Y.). Feb, 2012 | Pubmed ID: 22245738 PET/磁共振的炎症的心肌梗死。 Journal of the American College of Cardiology. Jan, 2012 | Pubmed ID: 22222080 急性心肌梗死快速单核细胞动力学来维持,髓外 Monocytopoiesis。 The Journal of Experimental Medicine. Jan, 2012 | Pubmed ID: 22213805 Bioorthogonal 反应对启用同步、 选择性、 多目标的成像。 Angewandte Chemie (International Ed. in English). Jan, 2012 | Pubmed ID: 22162316 髓外造血功能生成 Ly 6Chigh 单核细胞的渗透动脉粥样硬化病变。 Circulation. Jan, 2012 | Pubmed ID: 22144566 血管炎: 针对炎症酶过氧化物酶分子影像。 Radiology. Jan, 2012 | Pubmed ID: 22084204 贝伐单抗与血管抑素武装 OHSV 增加抗血管生成,并减少 U87 胶质瘤中贝伐单抗诱导的入侵。 Molecular Therapy : the Journal of the American Society of Gene Therapy. Jan, 2012 | Pubmed ID: 21915104 发展的分泌蛋白和酸性和富含半胱氨酸 (SPARC) 针对转移性前列腺癌的预后分子成像的纳米粒子。 Journal of Nanomedicine & Nanotechnology. Aug, 2011 | Pubmed ID: 22319675 活体成像。 Cell. Nov, 2011 | Pubmed ID: 22118457 超分子主客体相互作用的标签和细胞生物标志物的检测。 Angewandte Chemie (International Ed. in English). Nov, 2011 | Pubmed ID: 22113923 面试方式: 纳米药物在肿瘤学: 小型化的巨大目的的手段。卡拉 · 萨顿的面试。 Nanomedicine (London, England). Nov, 2011 | Pubmed ID: 22077461 使用 Bioorthogonal 化学和磁共振诊断的特定病原体检测。 Bioconjugate Chemistry. Dec, 2011 | Pubmed ID: 22043803 89Zr 标记的葡聚糖纳米粒子使体内巨噬细胞成像。 Bioconjugate Chemistry. Dec, 2011 | Pubmed ID: 22035047 不同容量的单核细胞亚群吞噬氧化铁纳米粒子。 PloS One. 2011 | Pubmed ID: 21984904 治疗 SiRNA 沉默小鼠单核细胞炎症。 Nature Biotechnology. Nov, 2011 | Pubmed ID: 21983520 Bioorthogonal Magnetofluorescent 纳米粒子的革兰氏阳性细菌检测无处不在。 ACS Nano. Nov, 2011 | Pubmed ID: 21967150 纳米粒子介导测量目标药物中的绑定的癌细胞。 ACS Nano. Nov, 2011 | Pubmed ID: 21962084 多核程序集加强生物磁纳米粒子的磁性。 Advanced Materials (Deerfield Beach, Fla.). Nov, 2011 | Pubmed ID: 21953810 合成及一系列的 1,245 嗪 Bioorthogonal 共轭的评价。 Bioconjugate Chemistry. Nov, 2011 | Pubmed ID: 21950520 Bioorthogonal 探针的 Polo 样激酶 1 成像和定量。 Angewandte Chemie (International Ed. in English). Sep, 2011 | Pubmed ID: 21948435 肿瘤药代动力学系统方法。 PloS One. 2011 | Pubmed ID: 21935441 基于逆电子需求第尔斯-阿尔德单击化学的正电子发射断层成像的 Radiometalated 抗体的构建模块化战略。 Bioconjugate Chemistry. Oct, 2011 | Pubmed ID: 21877749 通过针对特定病原体的凝血酶原激活葡萄球菌金黄色心内膜炎的体内检测。 Nature Medicine. Sep, 2011 | Pubmed ID: 21857652 寡核苷酸杂交法进行多路复用磁性标签放大。 Advanced Materials (Deerfield Beach, Fla.). Sep, 2011 | Pubmed ID: 21780311 使用第二代的荧光 Exendin-4 模拟的胰岛 β 细胞质量的精确测量。 Proceedings of the National Academy of Sciences of the United States of America. Aug, 2011 | Pubmed ID: 21768367 体内 PET 显像研究组蛋白化酶 18F Suberoylanilide 羟肟酸 (18F SAHA)。 Journal of Medicinal Chemistry. Aug, 2011 | Pubmed ID: 21721525 分析由体内显微镜和单个单元格的药效学研究肿瘤细胞有丝分裂和 Antimitotic 药物反应。 Cancer Research. Jul, 2011 | Pubmed ID: 21712408 二维血管内近红外荧光分子成像的炎症在动脉粥样硬化和支架血管损伤。 Journal of the American College of Cardiology. Jun, 2011 | Pubmed ID: 21679853 葡氧化铁纳米颗粒: 多用途平台的有针对性的分子影像学、 分子诊断和治疗。 Accounts of Chemical Research. Oct, 2011 | Pubmed ID: 21661727 四嗪类 Cycloadditions 的生物医学应用。 Accounts of Chemical Research. Sep, 2011 | Pubmed ID: 21627112 吲哚菁绿使血脂富、 红肿的动脉粥样硬化斑块的近红外荧光成像。 Science Translational Medicine. May, 2011 | Pubmed ID: 21613624 关于翻译的心血管分子影像学全国心、 肺、 血液研究所工作小组的报告。 Circulation. May, 2011 | Pubmed ID: 21576680 髓过氧化物酶磁共振成像鉴别肿瘤与瘤周脑水肿炎症。 Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jul, 2011 | Pubmed ID: 21558403 点的护理诊断微型磁共振系统。 Lab on a Chip. Jul, 2011 | Pubmed ID: 21547317 高度的磁核壳型纳米粒子的独特磁化机制。 Angewandte Chemie (International Ed. in English). May, 2011 | Pubmed ID: 21495138 体内的红移的荧光蛋白的层析成像。 Biomedical Optics Express. 2011 | Pubmed ID: 21483611 一元函数 Pentamethine 菁荧光的合成。 Dyes and Pigments : an International Journal. Apr, 2011 | Pubmed ID: 21475610 分子生物标志物和单元格使用纳米磁性材料和磁共振诊断检测。 Methods in Molecular Biology (Clifton, N.J.). 2011 | Pubmed ID: 21424441 两个高产、 步骤 18F 贴标 18F PARP1 抑制剂的战略。 ChemMedChem. Mar, 2011 | Pubmed ID: 21360818 探测细胞内的生物标志物和细胞激活使用纳米传感器和 Bioorthogonal 化学调解员。 ACS Nano. Apr, 2011 | Pubmed ID: 21351804 微型核磁共振快速分子分析的人类肿瘤标本。 Science Translational Medicine. Feb, 2011 | Pubmed ID: 21346169 合成和体内成像法化学正交清道夫辅助高性能 18F 标记 PARP1 抑制剂。 Angewandte Chemie (International Ed. in English). Feb, 2011 | Pubmed ID: 21328671 巨噬细胞中的纳米粒子正电子发射断层扫描型计算机断层扫描仪主动脉瘤的检测。 Arteriosclerosis, Thrombosis, and Vascular Biology. Apr, 2011 | Pubmed ID: 21252070 增强体内成像新陈代谢素细胞表面的记者。 Analytical Chemistry. Feb, 2011 | Pubmed ID: 21214190 高产、 两步 (18) F (18) F PARP1 抑制贴标战略。 ChemMedChem. Jan, 2011 | Pubmed ID: 21207434 龙 (排斥指导分子 B) 抑制巨噬细胞白细胞介素-6 表达。 Journal of Immunology (Baltimore, Md. : 1950). Feb, 2011 | Pubmed ID: 21187450 1A 型糖尿病患者的胰岛炎症的无创性成像技术。 The Journal of Clinical Investigation. Jan, 2011 | Pubmed ID: 21123946 人类胚胎干细胞源性微血管移植后心肌梗死心肌组织保存。 Biomaterials. Feb, 2011 | Pubmed ID: 21035182 骨髓基质干细胞移植需要主机 CD11b + 脾细胞并阻止实验小肠结肠炎。 Gastroenterology. Mar, 2011 | Pubmed ID: 20955701 高效免疫磁珠分离的自组装磁性过滤器。 Lab on a Chip. Jan, 2011 | Pubmed ID: 20949198 皮下体内的抗体吸收: 条件依赖抗原表达水平。 Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging. Aug, 2011 | Pubmed ID: 20809210 术中近红外荧光造影 (NIRFC) 在胆道损伤的小鼠模型: 答复。 World Journal of Surgery. Mar, 2011 | Pubmed ID: 20645091 磁性纳米粒子与磁共振成像监测 MTOR 抑制下游抗血管生成作用。 Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging. Apr, 2011 | Pubmed ID: 20559742 磁性纳米粒的生物医学基于核磁共振诊断。 Beilstein Journal of Nanotechnology. 2010 | Pubmed ID: 21977404 WNT5A/JNK 和 FGF/MAPK 通路调节塑造脊椎动物肢芽细胞事件。 Current Biology : CB. Nov, 2010 | Pubmed ID: 21055947 Bioorthogonal 小分子配为 PARP1 的在活细胞中的影像。 Chembiochem : a European Journal of Chemical Biology. Nov, 2010 | Pubmed ID: 20967817 高分辨率磁共振成像增强与超顺磁性纳米粒子措施巨噬细胞在动脉粥样硬化的负担。 Circulation. Oct, 2010 | Pubmed ID: 20937980 血管紧张素转换酶抑制阻止小鼠心肌梗死其脾藏从单核细胞释放。 Circulation Research. Nov, 2010 | Pubmed ID: 20930148 检测的近红外成像在肿瘤切除术中的局限性。 Journal of Surgical Oncology. Dec, 2010 | Pubmed ID: 20872807 在癌症的体内成像。 Cold Spring Harbor Perspectives in Biology. Dec, 2010 | Pubmed ID: 20861158 羧甲基聚乙烯醇稳定的掺杂磁性液体生物的应用程序。 Advanced Materials (Deerfield Beach, Fla.). Dec, 2010 | Pubmed ID: 20859943 定量纳米结构-活性关系建模。 ACS Nano. Oct, 2010 | Pubmed ID: 20857979 有针对性的癌症检测的 Nanoagents。 Molecular Oncology. Dec, 2010 | Pubmed ID: 20851695 有针对性的巨噬细胞炎性动脉粥样硬化中消融的光激活 Theranostic Nanoagent。 Small (Weinheim an Der Bergstrasse, Germany). Sep, 2010 | Pubmed ID: 20721949 吡格列酮抑制体内小鼠颈动脉粥样硬化炎症反应: 双目标荧光分子成像的新型检测。 Arteriosclerosis, Thrombosis, and Vascular Biology. Oct, 2010 | Pubmed ID: 20689078 Bioorthogonal 化学放大纳米粒子具有约束力和增强细胞检测的灵敏度。 Nature Nanotechnology. Sep, 2010 | Pubmed ID: 20676091 动脉和主动脉瓣钙化与骨质疏松症骨重塑成反比关联: 炎症的作用。 European Heart Journal. Aug, 2010 | Pubmed ID: 20601388 近红外成像的胰腺 β 细胞的荧光探针。 Bioconjugate Chemistry. Jul, 2010 | Pubmed ID: 20583828 髓过氧化物酶富 Ly 6 C + 髓系细胞渗透同种异体移植和小鼠器官排斥反应的成像签名作出贡献。 The Journal of Clinical Investigation. Jul, 2010 | Pubmed ID: 20577051 动脉粥样硬化的分子成像: 一份进度报告。 Texas Heart Institute Journal / from the Texas Heart Institute of St. Luke's Episcopal Hospital, Texas Children's Hospital. 2010 | Pubmed ID: 20548813 磷脂酰肌醇 3-激酶调节亚基 P85alpha 可以施加通过生长因子信号转导负调控肿瘤抑制器属性。 Cancer Research. Jul, 2010 | Pubmed ID: 20530665 Bioorthogonal 和使用四嗪-降冰片烯环加成的量子点的高效共轭法的发展。 Journal of the American Chemical Society. Jun, 2010 | Pubmed ID: 20481508 动脉粥样硬化和成像目标的血管生物学。 Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. May, 2010 | Pubmed ID: 20395349 通过模型小鼠体内荧光成像材料快速生物相容性分析。 PloS One. 2010 | Pubmed ID: 20386609 混合 PET 光学成像使用有针对性的探测器。 Proceedings of the National Academy of Sciences of the United States of America. Apr, 2010 | Pubmed ID: 20385821 Ly-6C(hi) 单核细胞增多与动脉粥样硬化小鼠愈合受损的脑梗死。 Journal of the American College of Cardiology. Apr, 2010 | Pubmed ID: 20378083 分子探针活性与出生规范化的荧光光学投影层析成像的成像。 Optics Letters. Apr, 2010 | Pubmed ID: 20364226 磁性纳米生物传感器。 Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology. May-Jun, 2010 | Pubmed ID: 20336708 Bioorthogonal 开关探测成像在活细胞内的小分子。 Angewandte Chemie (International Ed. in English). Apr, 2010 | Pubmed ID: 20306505 原发性肺癌小鼠研究辐射生物学中的影像。 International Journal of Radiation Oncology, Biology, Physics. Mar, 2010 | Pubmed ID: 20206017 激活素 A 促进致多发性骨髓瘤骨溶解,发性骨髓瘤骨疾病很有希望的目标。 Proceedings of the National Academy of Sciences of the United States of America. Mar, 2010 | Pubmed ID: 20194748 Sirt6 组蛋白去乙酰酶调节葡萄糖稳态通过 Hif1alpha。 Cell. Jan, 2010 | Pubmed ID: 20141841 新型分子结合治疗和诊断活动揭示了基于干细胞的治疗的多个方面。 Stem Cells (Dayton, Ohio). Apr, 2010 | Pubmed ID: 20127797 术中近红外荧光造影 (NIRFC) 在胆道损伤的小鼠模型。 World Journal of Surgery. Feb, 2010 | Pubmed ID: 20033407 具有约束力的亲和性和针对性小分子修饰纳米粒子动力学分析。 Bioconjugate Chemistry. Jan, 2010 | Pubmed ID: 20028085 及早识别使用铁氧化物的主动脉瓣硬化的 MRI 增强。 Journal of Magnetic Resonance Imaging : JMRI. Jan, 2010 | Pubmed ID: 20027578 可激活磁共振显像剂过氧化物遥感: 激活、 稳定性和毒性的机制。 Journal of the American Chemical Society. Jan, 2010 | Pubmed ID: 19968300 近红外荧光: 体内分子影像学中的应用。 Current Opinion in Chemical Biology. Feb, 2010 | Pubmed ID: 19879798 Vasculostatin (Vstat120) 表示溶瘤单纯疱疹病毒 1 增强抗肿瘤作用。 Molecular Therapy : the Journal of the American Society of Gene Therapy. Feb, 2010 | Pubmed ID: 19844198 自组装多功能的 Fe/氧化镁纳米球磁共振成像和高温。 Nanomedicine : Nanotechnology, Biology, and Medicine. Apr, 2010 | Pubmed ID: 19800988 小口径组织工程血管模型小鼠活体分子影像: 一项可行性研究。 Tissue Engineering. Part C, Methods. Aug, 2010 | Pubmed ID: 19751103 高吞吐量传输光学投影成像使用低成本的图形处理单元。 Optics Express. Dec, 2009 | Pubmed ID: 20052155 不带偏见的发现活体成像探测器通过体外分析的纳米粒子库。 Integrative Biology : Quantitative Biosciences from Nano to Macro. Apr, 2009 | Pubmed ID: 20023731 Diffractionless 梁在自由空间的绝热变化折射率在一个单一的模式中圆锥平板波导。 Optics Express. Nov, 2009 | Pubmed ID: 19997414 多色荧光活体活显微镜 (电影) 模型小鼠异种移植的外科肿瘤切除手术。 PloS One. 2009 | Pubmed ID: 19956597 分子 MRI 检测中转基因模型的慢性心衰的心肌细胞凋亡的低水平。 Circulation. Cardiovascular Imaging. Nov, 2009 | Pubmed ID: 19920045 同时延迟增强 MRI 与心肌细胞凋亡的分子 MRI 区分细胞凋亡和坏死心肌细胞在体内: 潜在时程抢救急性缺血。 Circulation. Cardiovascular Imaging. Nov, 2009 | Pubmed ID: 19920044 西妥昔单渥漫青霉素-抗作为一种双重的药物。 Bioconjugate Chemistry. Nov, 2009 | Pubmed ID: 19883074 动脉粥样硬化血管细胞黏附分子-1 表达的 PET-CT 成像的 18F 4V。 JACC. Cardiovascular Imaging. Oct, 2009 | Pubmed ID: 19833312 噁嗪共轭的纳米检测体内次氯酸酸和过氧亚硝酸盐的生成。 Journal of the American Chemical Society. Nov, 2009 | Pubmed ID: 19817443 加强社会投票和数据库驱动的文本分类的生物医学数据库中导航。 BMC Bioinformatics. 2009 | Pubmed ID: 19799796 小鼠使用生物相容性 Upconverting 纳米粒子的透射荧光成像。 Optics Letters. Sep, 2009 | Pubmed ID: 19724491 磁共振成像的一种新型的小鼠工作心脏移植模型。 Circulation. Heart Failure. May, 2009 | Pubmed ID: 19718275 快速和敏感 Pretargeted 通过四嗪/跨-cyclooctene 环加成癌细胞的标签。 Angewandte Chemie (International Ed. in English). 2009 | Pubmed ID: 19697389 高产合成的亲水 Conjugatable Chlorins 和 Bacteriochlorins。 Organic & Biomolecular Chemistry. Sep, 2009 | Pubmed ID: 19675897 针对髓过氧化物酶的酶敏感磁共振成像标识活动炎症的实验性家兔动脉粥样硬化斑块。 Circulation. Aug, 2009 | Pubmed ID: 19652086 Abrogation 的自发 Viridin 前体和受损的中性粒细胞和血管内皮细胞功能与协会的小鼠抗体诱发关节炎。 Arthritis and Rheumatism. Aug, 2009 | Pubmed ID: 19644878 脾藏单核细胞和它们部署到炎症站点的标识。 Science (New York, N.Y.). Jul, 2009 | Pubmed ID: 19644120 快速检测和分析的细针穿刺液中的癌症细胞。 Proceedings of the National Academy of Sciences of the United States of America. Jul, 2009 | Pubmed ID: 19620715 Sulfonamidophenyl 卟啉模型可激活的光敏剂的合成与光物理属性。 The Journal of Organic Chemistry. Aug, 2009 | Pubmed ID: 19610602 动脉粥样硬化与自定义纳米传感器中蛋白酶活性的体内 FMT CT 成像中的混合。 Arteriosclerosis, Thrombosis, and Vascular Biology. Oct, 2009 | Pubmed ID: 19608968 细胞死亡的磁共振检测 DNA 结合 Gd 螯合物。 Chemical Communications (Cambridge, England). Aug, 2009 | Pubmed ID: 19597620 Upconverting 发光纳米材料: 体内成像中的应用。 Chemical Communications (Cambridge, England). Jul, 2009 | Pubmed ID: 19585016 核显微镜: 定量成像钆分布在组织切片中的一种新技术。 Microscopy and Microanalysis : the Official Journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada. Aug, 2009 | Pubmed ID: 19575834 淋巴细胞白血病纳米颗粒增强的磁共振成像 (LNMRI) 标识前打捞放射治疗前列腺癌患者隐匿性淋巴结转移。 Clinical Imaging. Jul-Aug, 2009 | Pubmed ID: 19559353 超灵敏检测细菌使用核壳型纳米粒子和核磁共振过滤系统。 Angewandte Chemie (International Ed. in English). 2009 | Pubmed ID: 19554581 苏尼替尼和放射治疗的疗效观察转基因小鼠模型的软组织肉瘤。 International Journal of Radiation Oncology, Biology, Physics. Jul, 2009 | Pubmed ID: 19545786 在频率选择性的反转恢复磁共振造影 (铁 MRA) 的双重对比增强机制。 Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. Aug, 2009 | Pubmed ID: 19526511 一种稳定的 Demethoxyviridin 衍生物抑制 PI3 激酶。 Bioorganic & Medicinal Chemistry Letters. Aug, 2009 | Pubmed ID: 19523825 抗增殖抑制作用的自发 Viridin 前体药物。 Molecular Cancer Therapeutics. Jun, 2009 | Pubmed ID: 19509266 单核细胞子集动力学在人类动脉粥样硬化可以使用磁性纳米传感器分析。 PloS One. 2009 | Pubmed ID: 19461894 检测血管内血栓的多式联运 Nanoagents。 Bioconjugate Chemistry. Jun, 2009 | Pubmed ID: 19456115 癌症监测的植入式诊断设备。 Biosensors & Bioelectronics. Jul, 2009 | Pubmed ID: 19442510 内源性肿瘤相关巨噬细胞的行为评估体内使用功能性纳米粒子。 Neoplasia (New York, N.Y.). May, 2009 | Pubmed ID: 19412430 针对 EGFRvIII 表示胶质母细胞瘤的基因工程的 T 细胞。 Journal of Neuro-oncology. Sep, 2009 | Pubmed ID: 19387557 单核细胞亚群在动脉粥样硬化的异构的体内行为。 Arteriosclerosis, Thrombosis, and Vascular Biology. Oct, 2009 | Pubmed ID: 19372462 光学和多模态分子影像: 动脉粥样硬化的见解。 Arteriosclerosis, Thrombosis, and Vascular Biology. Jul, 2009 | Pubmed ID: 19359659 分子影像学的先天免疫细胞功能的移植排斥反应。 Circulation. Apr, 2009 | Pubmed ID: 19332470 纳米粒子目标交互并行抗体蛋白的相互作用。 Analytical Chemistry. May, 2009 | Pubmed ID: 19323458 动脉和主动脉瓣膜钙化废除内源性组织蛋白酶 S 虚慢性肾脏病。 Circulation. Apr, 2009 | Pubmed ID: 19307473 评估治疗效果和工程人间充质干细胞治疗癌症的命运。 Proceedings of the National Academy of Sciences of the United States of America. Mar, 2009 | Pubmed ID: 19264968 肿瘤治疗的突变体钠通道。 Molecular Therapy : the Journal of the American Society of Gene Therapy. May, 2009 | Pubmed ID: 19259066 瘤表皮生长因子信号转导与肿瘤抑制基因中的函数 Gliomagenesis 损失进行合作。 Proceedings of the National Academy of Sciences of the United States of America. Feb, 2009 | Pubmed ID: 19196966 荧光光学投影层析成像的归一化出生的比率。 Optics Letters. Feb, 2009 | Pubmed ID: 19183644 联合的磁共振和荧光成像的生活鼠标脑揭示了脑胶质瘤化疗反应。 NeuroImage. Apr, 2009 | Pubmed ID: 19154791 18F 标记体内 PET-CT 成像的纳米粒子。 Bioconjugate Chemistry. Feb, 2009 | Pubmed ID: 19138113 卵巢癌转移瘤术中荧光定量蛋白酶成像技术在临床前模型中的改进的检测。 Gynecologic Oncology. Mar, 2009 | Pubmed ID: 19135233 控制的蛋白质的多功能单附件点试剂。 Bioconjugate Chemistry. Jan, 2009 | Pubmed ID: 19072220 组织蛋白酶 K 介导荧光的无创性光学检测表明体外和体内的破骨细胞活性。 Bone. Feb, 2009 | Pubmed ID: 19007918 Notch 在心血管疾病和钙化。 Current Cardiology Reviews. Aug, 2008 | Pubmed ID: 19936191 多路复用技术分析的荧光寿命时间域 Fluorimeter 的开发。 IEEE Transactions on Biomedical Circuits and Systems. Sep, 2008 | Pubmed ID: 19830273 设计与论证的一个小动物上转换成像仪。 Optics Express. Dec, 2008 | Pubmed ID: 19104605 BRAF 激活将启动,但不维护侵袭性前列腺癌。 PloS One. 2008 | Pubmed ID: 19079609 一元函数碳菁染料的生物和 Bioorthogonal 共轭。 Bioconjugate Chemistry. Dec, 2008 | Pubmed ID: 19053316 基于四嗪类的 Cycloadditions: Pretargeted 活细胞成像技术中的应用。 Bioconjugate Chemistry. Dec, 2008 | Pubmed ID: 19053305 在小鼠模型气道过敏性炎症的炎症和治疗反应的实时评估。 The Journal of Clinical Investigation. Dec, 2008 | Pubmed ID: 19033674 肌醇和 MEK 抑制剂治疗克拉什 G12D 突变和 PIK3CA H1047R 小鼠肺癌的有效利用。 Nature Medicine. Dec, 2008 | Pubmed ID: 19029981 早期的光子断层扫描允许在小鼠中的荧光检测肺癌与疾病进展的体内。 Proceedings of the National Academy of Sciences of the United States of America. Dec, 2008 | Pubmed ID: 19015534 跟踪由遥感酶过氧化物酶对脑卒中体内的炎症反应。 Proceedings of the National Academy of Sciences of the United States of America. Nov, 2008 | Pubmed ID: 19011099 针对多个通路脑胶质瘤干细胞与病毒性交付 S 径及替莫唑胺。 Molecular Cancer Therapeutics. Nov, 2008 | Pubmed ID: 19001440 和平号空间站 296 调节血管内皮细胞生长因子受体过度表达。 Cancer Cell. Nov, 2008 | Pubmed ID: 18977327 磁共振成像监测 Antihedgehog 治疗胰腺癌异种移植模型中的生理变化。 Pancreas. Nov, 2008 | Pubmed ID: 18953259 罗格列酮与卡铂联用耐药肺癌的回归。 Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Oct, 2008 | Pubmed ID: 18927287 实时导管分子传感的 Proteolytically 活动动脉粥样硬化炎症。 Circulation. Oct, 2008 | Pubmed ID: 18852366 简化了的复杂的多功能纳米材料的合成。 Chemical Communications (Cambridge, England). Oct, 2008 | Pubmed ID: 18830495 综合纳米传感器,以确定级别和端粒酶的功能活动。 Neoplasia (New York, N.Y.). Oct, 2008 | Pubmed ID: 18813356 非共振造影: 一种新的方法来描绘船只 — — 幻影和兔的研究。 Radiology. Nov, 2008 | Pubmed ID: 18780823 半胱氨酸蛋白酶活性的实时成像显示局灶性炎症、 血管新生和息肉增长的动力。 PloS One. 2008 | Pubmed ID: 18698347 富含巨噬细胞的"正面对比"磁共振成像的高脂血症家兔动脉粥样硬化斑块的无创检测。 Journal of the American College of Cardiology. Aug, 2008 | Pubmed ID: 18672170 近红外荧光基于噬菌体粒子计量 Ph 值成像。 Bioconjugate Chemistry. Aug, 2008 | Pubmed ID: 18666791 人类乳腺癌癌症肿瘤模型: 分子成像的药物敏感性和 HER2 纽针对性治疗期间加药。 Radiology. Sep, 2008 | Pubmed ID: 18647846 有针对性的心肌损伤的影像。 Nature Clinical Practice. Cardiovascular Medicine. Aug, 2008 | Pubmed ID: 18641609 使用光纤共焦激光探针的健康和恶性组织的体内定量微血管构筑表型成像。 Translational Oncology. Jul, 2008 | Pubmed ID: 18633456 慢自活化增强了 Viridin 前体药物的效价。 Journal of Medicinal Chemistry. Aug, 2008 | Pubmed ID: 18630894 生物传感器芯片核磁共振检测和分子分析的单元格。 Nature Medicine. Aug, 2008 | Pubmed ID: 18607350 电极化学生成基于纳米粒子的核磁共振传感器的钙。 Langmuir : the ACS Journal of Surfaces and Colloids. Jul, 2008 | Pubmed ID: 18558729 多功能磁性纳米粒子进行有针对性的成像和治疗。 Advanced Drug Delivery Reviews. Aug, 2008 | Pubmed ID: 18508157 纳米材料生物活性的摄动分析。 Proceedings of the National Academy of Sciences of the United States of America. May, 2008 | Pubmed ID: 18492802 双峰病毒载体和活体成像揭示了神经干细胞实验胶质瘤模型中的命运。 The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Apr, 2008 | Pubmed ID: 18434519 敏感的核磁共振传感器检测到流感抗体。 Angewandte Chemie (International Ed. in English). 2008 | Pubmed ID: 18428168 针对纳米粒的早期胰腺癌的影像。 PLoS Medicine. Apr, 2008 | Pubmed ID: 18416599 分子肿瘤学时代的影像。 Nature. Apr, 2008 | Pubmed ID: 18385732 使用 Hepsin 对象的成像剂的早期前列腺癌的检测。 Cancer Research. Apr, 2008 | Pubmed ID: 18381435 磁性纳米粒的磁共振成像: 代理、 技术和心血管的应用程序。 Basic Research in Cardiology. Mar, 2008 | Pubmed ID: 18324368 心血管分子靶点的先生光学成像。 Basic Research in Cardiology. Mar, 2008 | Pubmed ID: 18324364 先生的粘度测定的磁微粒聚合。 Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. Mar, 2008 | Pubmed ID: 18306403 Lymphotrophic 纳米颗粒增强磁共振成像评估肾细胞癌的淋巴结的评价使用的试验。 Urology. Apr, 2008 | Pubmed ID: 18295316 使用荧光的钙结石的影像学一种新方法。 The Journal of Urology. Apr, 2008 | Pubmed ID: 18295253 转谷氨酰胺活性在急性梗塞预测治疗结果和左心室重构: 对 FXIII 治疗与心肌梗死患者抗凝血酶使用的影响。 European Heart Journal. Feb, 2008 | Pubmed ID: 18276618 可激活的磁共振成像代理报告愈合梗塞髓过氧化物酶活性并通过检测阿伐他汀对缺血再灌注损伤的抗炎作用。 Circulation. Mar, 2008 | Pubmed ID: 18268141 针对髓过氧化物酶的成像的小鼠实验性自身免疫性脑脊髓炎的活跃炎性病变。 Brain : a Journal of Neurology. Apr, 2008 | Pubmed ID: 18234693 荧光素分泌的酶为 Ex 体内监测体内的过程。 Nature Methods. Feb, 2008 | Pubmed ID: 18204457 单核细胞贩运到动脉粥样硬化病变的无创性活体成像。 Circulation. Jan, 2008 | Pubmed ID: 18172031 纳米 PET-CT 成像的巨噬细胞在炎症动脉粥样硬化。 Circulation. Jan, 2008 | Pubmed ID: 18158358 无创性影像学在心血管疾病中的细胞凋亡。 Heart Failure Reviews. Jun, 2008 | Pubmed ID: 18074226 巯基成像具有高度选择性的荧光探针。 Organic Letters. Jan, 2008 | Pubmed ID: 18062694 用于临床癌症分期新丸注射纳米粒子的实用程序。 Neoplasia (New York, N.Y.). Dec, 2007 | Pubmed ID: 18084623 肥大细胞是息肉发展重要组成部分造血。 Proceedings of the National Academy of Sciences of the United States of America. Dec, 2007 | Pubmed ID: 18077429 溶瘤病毒治疗疗效肿瘤微环境调节的影响。 Journal of the National Cancer Institute. Dec, 2007 | Pubmed ID: 18042934 成骨将与体内分子成像评价早期动脉粥样硬化炎症相关联。 Circulation. Dec, 2007 | Pubmed ID: 18040026 治疗心肌按顺序动员两个单核细胞亚群与分歧和补充性职能。 The Journal of Experimental Medicine. Nov, 2007 | Pubmed ID: 18025128 荧光探针在动脉粥样硬化相关巨噬细胞中的髓过氧化物酶活性的检测方法。 Chemistry & Biology. Nov, 2007 | Pubmed ID: 18022561 近红外荧光信号将通过大型人体器官为临床研究传播吗?勘误表。 Optics Letters. Sep, 2002 | Pubmed ID: 18026531 弥漫性光学层析成像中的任意几何形状的快速分析逼近。 Optics Letters. Apr, 2002 | Pubmed ID: 18007854 近红外荧光信号将通过大型人体器官为临床研究传播吗? Optics Letters. Mar, 2002 | Pubmed ID: 18007794 微流控芯片上捕获环加成反应可逆地固定小分子或多组分结构的生物传感器应用 Carlos Tassa1, Monty Liong1, Scott Hilderbrand1, Jason E. Sandler1, Thomas Reiner1, Edmund J. Keliher1, Ralph Weissleder1, Stanley Y. Shaw1 1Center for Systems Biology, Massachusetts General Hospital JoVE 50772 Chemistry 为介观荧光体层摄影术在体内成像的发展果蝇 Claudio Vinegoni1, Daniel Razansky2, Chrysoula Pitsouli3, Norbert Perrimon3, Vasilis Ntziachristos2, Ralph Weissleder1 1Center for Systems Biology, Massachusetts General Hospital, 2Institute for Biological and Medical Imaging (IBMI), Technical University of Munich and Helmholtz Center Munich, 3Department of Genetics, Harvard Medical School and Howard Hughes Medical Institute JoVE 1510 Biology 生于正常化荧光整个心脏成像的光学投影层析成像 Claudio Vinegoni1,2, Daniel Razansky3, Jose-Luiz Figueiredo1,2, Lyuba Fexon1,2, Misha Pivovarov1,2, Matthias Nahrendorf1,2, Vasilis Ntziachristos3, Ralph Weissleder1,2 1Center for Systems Biology, Harvard Medical School, 2Center for Systems Biology, MGH - Massachusetts General Hospital, 3Institute for Biological and Medical Imaging, Technical University of Munich and Helmholtz Center Munich JoVE 1389 Biology
微流控芯片上捕获环加成反应可逆地固定小分子或多组分结构的生物传感器应用 Carlos Tassa1, Monty Liong1, Scott Hilderbrand1, Jason E. Sandler1, Thomas Reiner1, Edmund J. Keliher1, Ralph Weissleder1, Stanley Y. Shaw1 1Center for Systems Biology, Massachusetts General Hospital JoVE 50772 Chemistry
为介观荧光体层摄影术在体内成像的发展果蝇 Claudio Vinegoni1, Daniel Razansky2, Chrysoula Pitsouli3, Norbert Perrimon3, Vasilis Ntziachristos2, Ralph Weissleder1 1Center for Systems Biology, Massachusetts General Hospital, 2Institute for Biological and Medical Imaging (IBMI), Technical University of Munich and Helmholtz Center Munich, 3Department of Genetics, Harvard Medical School and Howard Hughes Medical Institute JoVE 1510 Biology
生于正常化荧光整个心脏成像的光学投影层析成像 Claudio Vinegoni1,2, Daniel Razansky3, Jose-Luiz Figueiredo1,2, Lyuba Fexon1,2, Misha Pivovarov1,2, Matthias Nahrendorf1,2, Vasilis Ntziachristos3, Ralph Weissleder1,2 1Center for Systems Biology, Harvard Medical School, 2Center for Systems Biology, MGH - Massachusetts General Hospital, 3Institute for Biological and Medical Imaging, Technical University of Munich and Helmholtz Center Munich JoVE 1389 Biology