In JoVE (1)
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Articles by Rita Gutorov in JoVE
Electrophysiological Method for Whole-cell Voltage Clamp Recordings from Drosophila Photoreceptors Ben Katz*1, Rita Gutorov*1, Elisheva Rhodes-Mordov1, Roger C. Hardie2, Baruch Minke1 1Department of Medical Neurobiology, Faculty of Medicine and the Edmond and Lily Safra Center for Brain Sciences (ELSC), Hebrew University, 2Department of Physiology, Development and Neuroscience, University of Cambridge Whole-cell recordings from Drosophila melanogaster photoreceptors enable the measurement of spontaneous dark bumps, quantum bumps, macroscopic responses to light, and current-voltage relationships under various conditions. In combination with D. melanogaster genetic manipulation tools, this method enables the study of the ubiquitous inositol-lipid signaling pathway and its target, the TRP channel.