Robert Clarke

Publications

• Large-Scale Gene-Centric Meta-Analysis Across 39 Studies Identifies Type 2 Diabetes Loci
  American Journal of Human Genetics. Feb, 2012  |   Pubmed ID: 22325160
• Lack of Caveolin-1 (P132L) Somatic Mutations in Breast Cancer
  Breast Cancer Research and Treatment. Feb, 2012  |   Pubmed ID: 22310961
• Influence of Berry-Polyphenols on Receptor Signaling and Cell-Death Pathways: Implications for Breast Cancer Prevention
  Journal of Agricultural and Food Chemistry. Feb, 2012  |   Pubmed ID: 22300613
• A Genome-wide Association Search for Type 2 Diabetes Genes in African Americans
  PloS One. 2012  |   Pubmed ID: 22238593
• Response to Ravnskov Et Al. on Saturated Fat and CHD
  The British Journal of Nutrition. Feb, 2012  |   Pubmed ID: 22153203
• Response to Hoenselaar from Pedersen Et Al
  The British Journal of Nutrition. Feb, 2012  |   Pubmed ID: 22153148
• Vitamin E Succinate Inhibits Survivin and Induces Apoptosis in Pancreatic Cancer Cells
  Genes & Nutrition. Jan, 2012  |   Pubmed ID: 21842182
• Gamma-tocotrienol Induced Apoptosis is Associated with Unfolded Protein Response in Human Breast Cancer Cells
  The Journal of Nutritional Biochemistry. Jan, 2012  |   Pubmed ID: 21429729
• GIST: A Gibbs Sampler to Identify Intracellular Signal Transduction Pathways
  Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference. Aug, 2011  |   Pubmed ID: 22254833
• Long-term Weight Loss and Prevention of Cardiovascular Disease
  Circulation. Dec, 2011  |   Pubmed ID: 22184040
• Blood Pressure Loci Identified with a Gene-centric Array
  American Journal of Human Genetics. Dec, 2011  |   Pubmed ID: 22100073
• The Devil is in the Methods: Lineage Tracing, Functional Screens and Sequencing, Hormones, Tumour-stroma Interactions, and Expansion of Human Breast Tumours As Xenografts
  Breast Cancer Research : BCR. Oct, 2011  |   Pubmed ID: 22017807
• Identifying Cancer Biomarkers by Network-constrained Support Vector Machines
  BMC Systems Biology. 2011  |   Pubmed ID: 21992556
• G-DOC: a Systems Medicine Platform for Personalized Oncology
  Neoplasia (New York, N.Y.). Sep, 2011  |   Pubmed ID: 21969811
• NTP-CERHR Expert Panel Report on the Developmental Toxicity of Soy Infant Formula
  Birth Defects Research. Part B, Developmental and Reproductive Toxicology. Oct, 2011  |   Pubmed ID: 21948615
• Autophagy and Endocrine Resistance in Breast Cancer
  Expert Review of Anticancer Therapy. Aug, 2011  |   Pubmed ID: 21916582
• Dickkopf1 Regulates Fate Decision and Drives Breast Cancer Stem Cells to Differentiation: an Experimentally Supported Mathematical Model
  PloS One. 2011  |   Pubmed ID: 21915302
• Genetic Variants in Novel Pathways Influence Blood Pressure and Cardiovascular Disease Risk
  Nature. Oct, 2011  |   Pubmed ID: 21909115
• Genome-wide Association Study Identifies Six New Loci Influencing Pulse Pressure and Mean Arterial Pressure
  Nature Genetics. Oct, 2011  |   Pubmed ID: 21909110
• The Importance of Reducing SFA to Limit CHD
  The British Journal of Nutrition. Oct, 2011  |   Pubmed ID: 21906408
• Cannibalism, Cell Survival, and Endocrine Resistance in Breast Cancer
  Breast Cancer Research : BCR. 2011  |   Pubmed ID: 21884644
• Genome-wide Association Identifies Nine Common Variants Associated with Fasting Proinsulin Levels and Provides New Insights into the Pathophysiology of Type 2 Diabetes
  Diabetes. Oct, 2011  |   Pubmed ID: 21873549
• Association of Cognitive Impairment with Combinations of Vitamin B₁₂-related Parameters
  Clinical Chemistry. Oct, 2011  |   Pubmed ID: 21836078
• Profile of Robert Clarke. Interviewed by Kristie Nybo, Ph.D
  BioTechniques. Jun, 2011  |   Pubmed ID: 21781032
• Breast Cancer Stem Cells and Their Role in Resistance to Endocrine Therapy
  Hormones & Cancer. Apr, 2011  |   Pubmed ID: 21761332
• Dynamic Modelling of Oestrogen Signalling and Cell Fate in Breast Cancer Cells
  Nature Reviews. Cancer. Jul, 2011  |   Pubmed ID: 21677677
• Homocysteine, B Vitamins, and the Risk of Cardiovascular Disease
  Clinical Chemistry. Aug, 2011  |   Pubmed ID: 21666070
• Overexpression of the Dominant-negative Form of Interferon Regulatory Factor 1 in Oligodendrocytes Protects Against Experimental Autoimmune Encephalomyelitis
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2011  |   Pubmed ID: 21653838
• Meta Analysis of Candidate Gene Variants Outside the LPA Locus with Lp(a) Plasma Levels in 14,500 Participants of Six White European Cohorts
  Atherosclerosis. Aug, 2011  |   Pubmed ID: 21592478
• Aspects of Benthic Decapod Diversity and Distribution from Rocky Nearshore Habitat at Geographically Widely Dispersed Sites
  PloS One. 2011  |   Pubmed ID: 21533220
• Physiological Responses to Near-Miss Outcomes and Personal Control During Simulated Gambling
  Journal of Gambling Studies / Co-sponsored by the National Council on Problem Gambling and Institute for the Study of Gambling and Commercial Gaming. Apr, 2011  |   Pubmed ID: 21516368
• No Impact of KIF6 Genotype on Vascular Risk and Statin Response Among 18,348 Randomized Patients in the Heart Protection Study
  Journal of the American College of Cardiology. May, 2011  |   Pubmed ID: 21458191
• Motif-guided Sparse Decomposition of Gene Expression Data for Regulatory Module Identification
  BMC Bioinformatics. 2011  |   Pubmed ID: 21426557
• A Randomised Controlled Trial Investigating the Effect of Vitamin B12 Supplementation on Neurological Function in Healthy Older People: the Older People and Enhanced Neurological Function (OPEN) Study Protocol [ISRCTN54195799]
  Nutrition Journal. 2011  |   Pubmed ID: 21396086
• Association of Genetic Variation with Systolic and Diastolic Blood Pressure Among African Americans: the Candidate Gene Association Resource Study
  Human Molecular Genetics. Jun, 2011  |   Pubmed ID: 21378095
• Therapeutically Activating RB: Reestablishing Cell Cycle Control in Endocrine Therapy-resistant Breast Cancer
  Endocrine-related Cancer. Jun, 2011  |   Pubmed ID: 21367843
• Commentary: Lipoprotein(a) and Atherosclerosis
  International Journal of Epidemiology. Apr, 2011  |   Pubmed ID: 21330345
• Association Between C Reactive Protein and Coronary Heart Disease: Mendelian Randomisation Analysis Based on Individual Participant Data
  BMJ (Clinical Research Ed.). 2011  |   Pubmed ID: 21325005
• DDN: a CaBIG® Analytical Tool for Differential Network Analysis
  Bioinformatics (Oxford, England). Apr, 2011  |   Pubmed ID: 21296752
• Large-scale Candidate Gene Analysis of HDL Particle Features
  PloS One. 2011  |   Pubmed ID: 21283740
• Lipoprotein(a) Genetic Variants Associated with Coronary and Peripheral Vascular Disease but Not with Stroke Risk in the Heart Protection Study
  Circulation. Cardiovascular Genetics. Feb, 2011  |   Pubmed ID: 21252144
• Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height
  American Journal of Human Genetics. Jan, 2011  |   Pubmed ID: 21194676
• PUGSVM: a CaBIGâ„¢ Analytical Tool for Multiclass Gene Selection and Predictive Classification
  Bioinformatics (Oxford, England). Mar, 2011  |   Pubmed ID: 21186245
• Modifiable Risk Factors for Prostate Cancer Mortality in London: Forty Years of Follow-up in the Whitehall Study
  Cancer Causes & Control : CCC. Feb, 2011  |   Pubmed ID: 21116843
• Homocysteine and Vascular Disease: Review of Published Results of the Homocysteine-lowering Trials
  Journal of Inherited Metabolic Disease. Feb, 2011  |   Pubmed ID: 21069462
• Comprehensive CYP2D6 Genotype and Adherence Affect Outcome in Breast Cancer Patients Treated with Tamoxifen Monotherapy
  Breast Cancer Research and Treatment. Jan, 2011  |   Pubmed ID: 20809362
• Height Loss and Future Coronary Heart Disease in London: the Whitehall II Study
  Journal of Epidemiology and Community Health. May, 2011  |   Pubmed ID: 20805197
• Breast Cancer Stem Cells: Something out of Notching?
  Cancer Research. Nov, 2010  |   Pubmed ID: 21045140
• Effects of Lowering Homocysteine Levels with B Vitamins on Cardiovascular Disease, Cancer, and Cause-specific Mortality: Meta-analysis of 8 Randomized Trials Involving 37 485 Individuals
  Archives of Internal Medicine. Oct, 2010  |   Pubmed ID: 20937919
• Association Analyses of 249,796 Individuals Reveal 18 New Loci Associated with Body Mass Index
  Nature Genetics. Nov, 2010  |   Pubmed ID: 20935630
• Turnaround Strategies
  Trustee : the Journal for Hospital Governing Boards. Jun, 2010  |   Pubmed ID: 20632646
• The Embryonic Transcription Cofactor LBH is a Direct Target of the Wnt Signaling Pathway in Epithelial Development and in Aggressive Basal Subtype Breast Cancers
  Molecular and Cellular Biology. Sep, 2010  |   Pubmed ID: 20606007
• Orphan Nuclear Receptors in Breast Cancer Pathogenesis and Therapeutic Response
  Endocrine-related Cancer. Sep, 2010  |   Pubmed ID: 20576803
• Effects of Homocysteine-lowering with Folic Acid Plus Vitamin B12 Vs Placebo on Mortality and Major Morbidity in Myocardial Infarction Survivors: a Randomized Trial
  JAMA : the Journal of the American Medical Association. Jun, 2010  |   Pubmed ID: 20571015
• Saturated Fat and Heart Disease
  The American Journal of Clinical Nutrition. Aug, 2010  |   Pubmed ID: 20534745
• IFNgamma Restores Breast Cancer Sensitivity to Fulvestrant by Regulating STAT1, IFN Regulatory Factor 1, NF-kappaB, BCL2 Family Members, and Signaling to Caspase-dependent Apoptosis
  Molecular Cancer Therapeutics. May, 2010  |   Pubmed ID: 20457620
• Reconstruction of Gene Regulatory Modules in Cancer Cell Cycle by Multi-source Data Integration
  PloS One. 2010  |   Pubmed ID: 20422009
• Disruption of a Quorum Sensing Mechanism Triggers Tumorigenesis: a Simple Discrete Model Corroborated by Experiments in Mammary Cancer Stem Cells
  Biology Direct. 2010  |   Pubmed ID: 20406437
• The Proapoptotic Molecule BLID Interacts with Bcl-XL and Its Downregulation in Breast Cancer Correlates with Poor Disease-free and Overall Survival
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jun, 2010  |   Pubmed ID: 20400521
• Multilevel Support Vector Regression Analysis to Identify Condition-specific Regulatory Networks
  Bioinformatics (Oxford, England). Jun, 2010  |   Pubmed ID: 20375112
• Introducing a Professional Development Framework for Postgraduate Medical Supervisors in Secondary Care: Considerations, Constraints and Challenges
  Postgraduate Medical Journal. Apr, 2010  |   Pubmed ID: 20354042
• Knowledge-guided Gene Ranking by Coordinative Component Analysis
  BMC Bioinformatics. 2010  |   Pubmed ID: 20353603
• DBC-1 Mediates Endocrine Resistant Breast Cancer Cell Survival
  Cell Cycle (Georgetown, Tex.). Mar, 2010  |   Pubmed ID: 20237431
• BCL2 and CASP8 Regulation by NF-kappaB Differentially Affect Mitochondrial Function and Cell Fate in Antiestrogen-sensitive and -resistant Breast Cancer Cells
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jun, 2010  |   Pubmed ID: 20154269
• New Genetic Loci Implicated in Fasting Glucose Homeostasis and Their Impact on Type 2 Diabetes Risk
  Nature Genetics. Feb, 2010  |   Pubmed ID: 20081858
• Regulation of Breast Cancer Stem Cell Activity by Signaling Through the Notch4 Receptor
  Cancer Research. Jan, 2010  |   Pubmed ID: 20068161
• Co-inhibition of BCL-W and BCL2 Restores Antiestrogen Sensitivity Through BECN1 and Promotes an Autophagy-associated Necrosis
  PloS One. 2010  |   Pubmed ID: 20062536
• Cross Phenotype Normalization of Microarray Data
  Frontiers in Bioscience (Elite Edition). 2010  |   Pubmed ID: 20036868
• The Influence of EDTA and Citrate Anticoagulant Addition to Human Plasma on Information Recovery from NMR-based Metabolic Profiling Studies
  Molecular BioSystems. Jan, 2010  |   Pubmed ID: 20024083
• Exploring the Marine Biotic Index (AMBI): Variations on a Theme by Angel Borja
  Marine Pollution Bulletin. Apr, 2010  |   Pubmed ID: 20005531
• Frequent Loss of Heterozygosity at the Interferon Regulatory Factor-1 Gene Locus in Breast Cancer
  Breast Cancer Research and Treatment. May, 2010  |   Pubmed ID: 19697121
• Polymorphisms in LMNA and Near a SERPINA Gene Cluster Are Associated with Cognitive Function in Older People
  Neurobiology of Aging. Sep, 2010  |   Pubmed ID: 18848371
• Identification of Condition-specific Regulatory Modules Through Multi-level Motif and MRNA Expression Analysis
  International Journal of Computational Biology and Drug Design. 2009  |   Pubmed ID: 20054984
• Biomarker Identification by Knowledge-driven Multilevel ICA and Motif Analysis
  International Journal of Data Mining and Bioinformatics. 2009  |   Pubmed ID: 20052902
• Genetic Variants Associated with Lp(a) Lipoprotein Level and Coronary Disease
  The New England Journal of Medicine. Dec, 2009  |   Pubmed ID: 20032323
• The Role of Preclinical Animal Models in Breast Cancer Drug Development
  Breast Cancer Research : BCR. 2009  |   Pubmed ID: 20030874
• Forty-three Loci Associated with Plasma Lipoprotein Size, Concentration, and Cholesterol Content in Genome-wide Analysis
  PLoS Genetics. Nov, 2009  |   Pubmed ID: 19936222
• Life Expectancy in Relation to Cardiovascular Risk Factors: 38 Year Follow-up of 19,000 Men in the Whitehall Study
  BMJ (Clinical Research Ed.). 2009  |   Pubmed ID: 19762417
• It's All in the Details: Methods in Breast Development and Cancer
  Breast Cancer Research : BCR. 2009  |   Pubmed ID: 19691817
• Biomarkers of Dietary Energy Restriction in Women at Increased Risk of Breast Cancer
  Cancer Prevention Research (Philadelphia, Pa.). Aug, 2009  |   Pubmed ID: 19656771
• The Role of X-box Binding Protein-1 in Tumorigenicity
  Drug News & Perspectives. Jun, 2009  |   Pubmed ID: 19609461
• Reverse Engineering Module Networks by PSO-RNN Hybrid Modeling
  BMC Genomics. 2009  |   Pubmed ID: 19594874
• Genetic Loci Associated with C-reactive Protein Levels and Risk of Coronary Heart Disease
  JAMA : the Journal of the American Medical Association. Jul, 2009  |   Pubmed ID: 19567438
• Targeting Inhibitor of Apoptosis Proteins in Combination with ErbB Antagonists in Breast Cancer
  Breast Cancer Research : BCR. 2009  |   Pubmed ID: 19563669
• Identification of ZNF366 and PTPRD As Novel Determinants of Plasma Homocysteine in a Family-based Genome-wide Association Study
  Blood. Aug, 2009  |   Pubmed ID: 19525478
• The Joint Effects of Apolipoprotein B, Apolipoprotein A1, LDL Cholesterol, and HDL Cholesterol on Risk: 3510 Cases of Acute Myocardial Infarction and 9805 Controls
  European Heart Journal. Sep, 2009  |   Pubmed ID: 19520708
• Gene Network Signaling in Hormone Responsiveness Modifies Apoptosis and Autophagy in Breast Cancer Cells
  The Journal of Steroid Biochemistry and Molecular Biology. Mar, 2009  |   Pubmed ID: 19444933
• Genome-wide Association Study Identifies Eight Loci Associated with Blood Pressure
  Nature Genetics. Jun, 2009  |   Pubmed ID: 19430483
• Polymorphisms in the WNK1 Gene Are Associated with Blood Pressure Variation and Urinary Potassium Excretion
  PloS One. 2009  |   Pubmed ID: 19347040
• Body-mass Index and Cause-specific Mortality in 900 000 Adults: Collaborative Analyses of 57 Prospective Studies
  Lancet. Mar, 2009  |   Pubmed ID: 19299006
• Normal Breast Tissue Implanted into Athymic Nude Mice Identifies Biomarkers of the Effects of Human Pregnancy Levels of Estrogen
  Cancer Prevention Research (Philadelphia, Pa.). Mar, 2009  |   Pubmed ID: 19258541
• Resistance to Endocrine Therapy: Are Breast Cancer Stem Cells the Culprits?
  Journal of Mammary Gland Biology and Neoplasia. Mar, 2009  |   Pubmed ID: 19252972
• Vascular Risk Factors and Cognitive Function Among 3763 Participants in the Hypertension in the Very Elderly Trial (HYVET): a Cross-sectional Analysis
  International Psychogeriatrics / IPA. Apr, 2009  |   Pubmed ID: 19250558
• Risk Factors for Pancreatic Cancer Mortality: Extended Follow-up of the Original Whitehall Study
  Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology. Feb, 2009  |   Pubmed ID: 19190162
• Differential Dependency Network Analysis to Identify Condition-specific Topological Changes in Biological Networks
  Bioinformatics (Oxford, England). Feb, 2009  |   Pubmed ID: 19112081
• Plasma Phospholipid Fatty Acids and CHD in Older Men: Whitehall Study of London Civil Servants
  The British Journal of Nutrition. Jul, 2009  |   Pubmed ID: 19105853
• Common Variants at 30 Loci Contribute to Polygenic Dyslipidemia
  Nature Genetics. Jan, 2009  |   Pubmed ID: 19060906
• Network Motif-based Identification of Breast Cancer Susceptibility Genes
  Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference. 2008  |   Pubmed ID: 19164010
• Gene Signaling Pathways Mediating the Opposite Effects of Prepubertal Low-fat and High-fat N-3 Polyunsaturated Fatty Acid Diets on Mammary Cancer Risk
  Cancer Prevention Research (Philadelphia, Pa.). Dec, 2008  |   Pubmed ID: 19139003
• Are Stem-like Cells Responsible for Resistance to Therapy in Breast Cancer?
  Breast Disease. 2008  |   Pubmed ID: 19029627
• Annotating Breast Cancer Microarray Samples Using Ontologies
  AMIA ... Annual Symposium Proceedings / AMIA Symposium. AMIA Symposium. 2008  |   Pubmed ID: 18999108
• ERRgamma Mediates Tamoxifen Resistance in Novel Models of Invasive Lobular Breast Cancer
  Cancer Research. Nov, 2008  |   Pubmed ID: 18974135
• B Vitamins for Prevention of Cognitive Decline: Insufficient Evidence to Justify Treatment
  JAMA : the Journal of the American Medical Association. Oct, 2008  |   Pubmed ID: 18854547
• Knowledge-guided Multi-scale Independent Component Analysis for Biomarker Identification
  BMC Bioinformatics. 2008  |   Pubmed ID: 18837990
• The Removal of Multiplicative, Systematic Bias Allows Integration of Breast Cancer Gene Expression Datasets - Improving Meta-analysis and Prediction of Prognosis
  BMC Medical Genomics. 2008  |   Pubmed ID: 18803878
• CaBIG VISDA: Modeling, Visualization, and Discovery for Cluster Analysis of Genomic Data
  BMC Bioinformatics. 2008  |   Pubmed ID: 18801195
• Discrepancy Between Inferior Vena Cava and Right Atrial Oxygen Saturations As a Sign of Ischemia in the Mesenteric Circulation
  Journal of Critical Care. Sep, 2008  |   Pubmed ID: 18725041
• Bread Cofortified with Folic Acid and Vitamin B-12 Improves the Folate and Vitamin B-12 Status of Healthy Older People: a Randomized Controlled Trial
  The American Journal of Clinical Nutrition. Aug, 2008  |   Pubmed ID: 18689370
• Prolactin Receptor Antagonism Reduces the Clonogenic Capacity of Breast Cancer Cells and Potentiates Doxorubicin and Paclitaxel Cytotoxicity
  Breast Cancer Research : BCR. 2008  |   Pubmed ID: 18681966
• Incident Dementia and Blood Pressure Lowering in the Hypertension in the Very Elderly Trial Cognitive Function Assessment (HYVET-COG): a Double-blind, Placebo Controlled Trial
  Lancet Neurology. Aug, 2008  |   Pubmed ID: 18614402
• Is "usual" Blood Pressure a Proxy for 24-h Ambulatory Blood Pressure in Predicting Cardiovascular Outcomes?
  American Journal of Hypertension. Sep, 2008  |   Pubmed ID: 18600212
• A Ground Truth Based Comparative Study on Clustering of Gene Expression Data
  Frontiers in Bioscience : a Journal and Virtual Library. 2008  |   Pubmed ID: 18508478
• Response and Resistance to the Endocrine Prevention of Breast Cancer
  Advances in Experimental Medicine and Biology. 2008  |   Pubmed ID: 18497044
• The Origin of Estrogen Receptor Alpha-positive and Alpha-negative Breast Cancer
  Advances in Experimental Medicine and Biology. 2008  |   Pubmed ID: 18497032
• Plasma Homocysteine, but Not Folate or Vitamin B-12, Predicts Mortality in Older People in the United Kingdom
  The Journal of Nutrition. Jun, 2008  |   Pubmed ID: 18492844
• Cone and Rod Cells Have Different Target Preferences in Vitro As Revealed by Optical Tweezers
  Molecular Vision. 2008  |   Pubmed ID: 18432315
• Network Motif-based Identification of Transcription Factor-target Gene Relationships by Integrating Multi-source Biological Data
  BMC Bioinformatics. 2008  |   Pubmed ID: 18426580
• Folate and Vitamin B12 Status in Relation to Cognitive Impairment and Anaemia in the Setting of Voluntary Fortification in the UK
  The British Journal of Nutrition. Nov, 2008  |   Pubmed ID: 18341758
• Motif-directed Network Component Analysis for Regulatory Network Inference
  BMC Bioinformatics. 2008  |   Pubmed ID: 18315853
• Biomarkers of Inflammation Predict Both Vascular and Non-vascular Mortality in Older Men
  European Heart Journal. Mar, 2008  |   Pubmed ID: 18303034
• B-vitamins and Prevention of Dementia
  The Proceedings of the Nutrition Society. Feb, 2008  |   Pubmed ID: 18234134
• The Exon 1-8C/G SNP in the PSMA6 Gene Contributes Only a Small Amount to the Burden of Myocardial Infarction in 6946 Cases and 2720 Controls from a United Kingdom Population
  European Journal of Human Genetics : EJHG. Apr, 2008  |   Pubmed ID: 18231128
• Newly Identified Loci That Influence Lipid Concentrations and Risk of Coronary Artery Disease
  Nature Genetics. Feb, 2008  |   Pubmed ID: 18193043
• The Properties of High-dimensional Data Spaces: Implications for Exploring Gene and Protein Expression Data
  Nature Reviews. Cancer. Jan, 2008  |   Pubmed ID: 18097463
• Susceptibility to Coronary Artery Disease and Diabetes is Encoded by Distinct, Tightly Linked SNPs in the ANRIL Locus on Chromosome 9p
  Human Molecular Genetics. Mar, 2008  |   Pubmed ID: 18048406
• Classification Algorithms for Phenotype Prediction in Genomics and Proteomics
  Frontiers in Bioscience : a Journal and Virtual Library. 2008  |   Pubmed ID: 17981580
• Gene Module Identification from Microarray Data Using Nonnegative Independent Component Analysis
  Gene Regulation and Systems Biology. 2007  |   Pubmed ID: 19936101
• Blood Cholesterol and Vascular Mortality by Age, Sex, and Blood Pressure: a Meta-analysis of Individual Data from 61 Prospective Studies with 55,000 Vascular Deaths
  Lancet. Dec, 2007  |   Pubmed ID: 18061058
• Low Vitamin B-12 Status and Risk of Cognitive Decline in Older Adults
  The American Journal of Clinical Nutrition. Nov, 2007  |   Pubmed ID: 17991650
• Mammary Stem Cells and Breast Cancer--role of Notch Signalling
  Stem Cell Reviews. Jun, 2007  |   Pubmed ID: 17873349
• B Vitamins for the Prevention of Vascular Disease: Insufficient Evidence to Justify Treatment
  JAMA : the Journal of the American Medical Association. Sep, 2007  |   Pubmed ID: 17848657
• Origins of Breast Cancer Subtypes and Therapeutic Implications
  Nature Clinical Practice. Oncology. Sep, 2007  |   Pubmed ID: 17728710
• Gene Selection for Multiclass Prediction by Weighted Fisher Criterion
  EURASIP Journal on Bioinformatics & Systems Biology. 2007  |   Pubmed ID: 17713593
• Progressive Loss of Estrogen Receptor Alpha Cofactor Recruitment in Endocrine Resistance
  Molecular Endocrinology (Baltimore, Md.). Nov, 2007  |   Pubmed ID: 17666584
• Human X-box Binding Protein-1 Confers Both Estrogen Independence and Antiestrogen Resistance in Breast Cancer Cell Lines
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Dec, 2007  |   Pubmed ID: 17660348
• Cholesterol Fractions and Apolipoproteins As Risk Factors for Heart Disease Mortality in Older Men
  Archives of Internal Medicine. Jul, 2007  |   Pubmed ID: 17620530
• VISDA: an Open-source CaBIG Analytical Tool for Data Clustering and Beyond
  Bioinformatics (Oxford, England). Aug, 2007  |   Pubmed ID: 17540678
• The Association of Betaine, Homocysteine and Related Metabolites with Cognitive Function in Dutch Elderly People
  The British Journal of Nutrition. Nov, 2007  |   Pubmed ID: 17537289
• The A4396G Polymorphism in Interferon Regulatory Factor 1 is Frequently Expressed in Breast Cancer Cell Lines
  Cancer Genetics and Cytogenetics. May, 2007  |   Pubmed ID: 17498560
• Homocysteine and Cardiovascular Risk: Considering the Evidence in the Context of Study Design, Folate Fortification, and Statistical Power
  Clinical Chemistry. May, 2007  |   Pubmed ID: 17468406
• Survival in Relation to Angina Symptoms and Diagnosis Among Men Aged 70-90 Years: the Whitehall Study
  European Journal of Cardiovascular Prevention and Rehabilitation : Official Journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology. Apr, 2007  |   Pubmed ID: 17446808
• Novel Cell Culture Technique for Primary Ductal Carcinoma in Situ: Role of Notch and Epidermal Growth Factor Receptor Signaling Pathways
  Journal of the National Cancer Institute. Apr, 2007  |   Pubmed ID: 17440163
• Detection of Vitamin B12 Deficiency in Older People by Measuring Vitamin B12 or the Active Fraction of Vitamin B12, Holotranscobalamin
  Clinical Chemistry. May, 2007  |   Pubmed ID: 17363419
• Absence of Relationship Between MTTP Haplotypes and Longevity
  The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. Feb, 2007  |   Pubmed ID: 17339647
• Estrogen Deprivation for Breast Cancer Prevention
  Recent Results in Cancer Research. Fortschritte Der Krebsforschung. Progrès Dans Les Recherches Sur Le Cancer. 2007  |   Pubmed ID: 17302193
• Homocysteine, B Vitamins, and the Risk of Dementia
  The American Journal of Clinical Nutrition. Feb, 2007  |   Pubmed ID: 17284725
• Homocysteine-lowering Vitamin B Supplements Do Not Improve Cognitive Performance in Healthy Older Adults After Two Years
  Evidence-based Mental Health. Feb, 2007  |   Pubmed ID: 17255396
• Caveolin-1 Tyrosine Phosphorylation Enhances Paclitaxel-mediated Cytotoxicity
  The Journal of Biological Chemistry. Feb, 2007  |   Pubmed ID: 17190831
• Why Inhaling Salt Water Changes What We Exhale
  Journal of Colloid and Interface Science. Mar, 2007  |   Pubmed ID: 17161415
• Effects of B-vitamins on Plasma Homocysteine Concentrations and on Risk of Cardiovascular Disease and Dementia
  Current Opinion in Clinical Nutrition and Metabolic Care. Jan, 2007  |   Pubmed ID: 17143052
• Shaping the Pupil's Response to Light in the Hooded Rat
  Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale. Feb, 2007  |   Pubmed ID: 16955268
• Latent Variable and NICA Modeling of Pathway Gene Module Composite
  Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference. 2006  |   Pubmed ID: 17946342
• Inferring Network Interactions Using Recurrent Neural Networks and Swarm Intelligence
  Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference. 2006  |   Pubmed ID: 17946231
• Endocrine Therapy Resistance Can Be Associated with High Estrogen Receptor Alpha (ERalpha) Expression and Reduced ERalpha Phosphorylation in Breast Cancer Models
  Endocrine-related Cancer. Dec, 2006  |   Pubmed ID: 17158758
• Disruption of Estrogen Receptor DNA-binding Domain and Related Intramolecular Communication Restores Tamoxifen Sensitivity in Resistant Breast Cancer
  Cancer Cell. Dec, 2006  |   Pubmed ID: 17157789
• The Use of a Segmented Transducer for Rib Sparing in HIFU Treatments
  Ultrasound in Medicine & Biology. Nov, 2006  |   Pubmed ID: 17112961
• Estrogen Receptor Alpha Positive Breast Tumors and Breast Cancer Cell Lines Share Similarities in Their Transcriptome Data Structures
  International Journal of Oncology. Dec, 2006  |   Pubmed ID: 17089000
• High-throughput Genomic Technology in Research and Clinical Management of Breast Cancer. Exploiting the Potential of Gene Expression Profiling: is It Ready for the Clinic?
  Breast Cancer Research : BCR. 2006  |   Pubmed ID: 17076877
• Effect of Oral Vitamin B-12 with or Without Folic Acid on Cognitive Function in Older People with Mild Vitamin B-12 Deficiency: a Randomized, Placebo-controlled Trial
  The American Journal of Clinical Nutrition. Aug, 2006  |   Pubmed ID: 16895884
• Trans Fatty Acids and Coronary Heart Disease
  BMJ (Clinical Research Ed.). Jul, 2006  |   Pubmed ID: 16873835
• Physical and Functional Interactions Between Cas and C-Src Induce Tamoxifen Resistance of Breast Cancer Cells Through Pathways Involving Epidermal Growth Factor Receptor and Signal Transducer and Activator of Transcription 5b
  Cancer Research. Jul, 2006  |   Pubmed ID: 16849545
• Lymphotoxin-alpha Gene and Risk of Myocardial Infarction in 6,928 Cases and 2,712 Controls in the ISIS Case-control Study
  PLoS Genetics. Jul, 2006  |   Pubmed ID: 16839190
• Vitamin B12, Folic Acid, and the Prevention of Dementia
  The New England Journal of Medicine. Jun, 2006  |   Pubmed ID: 16807420
• Ovarian Steroids and the Human Breast: Regulation of Stem Cells and Cell Proliferation
  Maturitas. Jul, 2006  |   Pubmed ID: 16806749
• Regulation of the Nuclear Localization of the Human Nedd4-related WWP1 Protein by Notch
  Molecular Membrane Biology. May-Jun, 2006  |   Pubmed ID: 16785210
• Genome-wide Mapping of Susceptibility to Coronary Artery Disease Identifies a Novel Replicated Locus on Chromosome 17
  PLoS Genetics. May, 2006  |   Pubmed ID: 16710446
• Clinical Relevance of Low Serum Vitamin B12 Concentrations in Older People: the Banbury B12 Study
  Age and Ageing. Jul, 2006  |   Pubmed ID: 16709605
• AIB1 Gene Amplification and the Instability of PolyQ Encoding Sequence in Breast Cancer Cell Lines
  BMC Cancer. 2006  |   Pubmed ID: 16670003
• Effect of a Farnesyl Transferase Inhibitor (R115777) on Ductal Carcinoma in Situ of the Breast in a Human Xenograft Model and on Breast and Ovarian Cancer Cell Growth in Vitro and in Vivo
  Breast Cancer Research : BCR. 2006  |   Pubmed ID: 16611371
• Meta-analysis of Soy Intake and Breast Cancer Risk
  Journal of the National Cancer Institute. Apr, 2006  |   Pubmed ID: 16595782
• Interactions Among Polymorphisms in Folate-metabolizing Genes and Serum Total Homocysteine Concentrations in a Healthy Elderly Population
  The American Journal of Clinical Nutrition. Mar, 2006  |   Pubmed ID: 16522921
• Airborne Infectious Disease and the Suppression of Pulmonary Bioaerosols
  Drug Discovery Today. Jan, 2006  |   Pubmed ID: 16478691
• Optimized Multilayer Perceptrons for Molecular Classification and Diagnosis Using Genomic Data
  Bioinformatics (Oxford, England). Mar, 2006  |   Pubmed ID: 16403791
• Expression Patterns Among Interferon Regulatory Factor-1, Human X-box Binding Protein-1, Nuclear Factor Kappa B, Nucleophosmin, Estrogen Receptor-alpha and Progesterone Receptor Proteins in Breast Cancer Tissue Microarrays
  International Journal of Oncology. Jan, 2006  |   Pubmed ID: 16327981
• Human Breast Epithelial Stem Cells and Their Regulation
  The Journal of Pathology. Jan, 2006  |   Pubmed ID: 16294373
• Cause-specific Mortality in Old Age in Relation to Body Mass Index in Middle Age and in Old Age: Follow-up of the Whitehall Cohort of Male Civil Servants
  International Journal of Epidemiology. Feb, 2006  |   Pubmed ID: 16284405
• The Application of an Indicator Based on Taxonomic Distinctness for UK Marine Biodiversity Assessments
  Journal of Environmental Management. Jan, 2006  |   Pubmed ID: 16095807
• A Psychosocial Risk Assessment and Management Framework to Enhance Response to CBRN Terrorism Threats and Attacks
  Biosecurity and Bioterrorism : Biodefense Strategy, Practice, and Science. 2005  |   Pubmed ID: 16366841
• Multidrug Resistance/P-glycoprotein and Breast Cancer: Review and Meta-analysis
  Seminars in Oncology. Dec, 2005  |   Pubmed ID: 16360717
• Mechanisms of Disease: Prediction and Prevention of Breast Cancer--cellular and Molecular Interactions
  Nature Clinical Practice. Oncology. Dec, 2005  |   Pubmed ID: 16341119
• Mechanisms Mediating the Effects of Prepubertal (n-3) Polyunsaturated Fatty Acid Diet on Breast Cancer Risk in Rats
  The Journal of Nutrition. Dec, 2005  |   Pubmed ID: 16317153
• Combined Effects of Systolic Blood Pressure and Total Cholesterol on Cardiovascular Disease Risk
  Circulation. Nov, 2005  |   Pubmed ID: 16316963
• High Q-factor Microwave Fabry-Perot Resonator with Distributed Bragg Reflectors
  IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control. Sep, 2005  |   Pubmed ID: 16285441
• Evaluation of the Technical Performance of Novel Holotranscobalamin (holoTC) Assays in a Multicenter European Demonstration Project
  Clinical Chemistry and Laboratory Medicine : CCLM / FESCC. 2005  |   Pubmed ID: 16197298
• Antiestrogens, Aromatase Inhibitors, and Apoptosis in Breast Cancer
  Vitamins and Hormones. 2005  |   Pubmed ID: 16112269
• Homocysteine-lowering Trials for Prevention of Heart Disease and Stroke
  Seminars in Vascular Medicine. May, 2005  |   Pubmed ID: 16047274
• Homocysteine, B-vitamins, and the Risk of Cardiovascular Disease
  Seminars in Vascular Medicine. May, 2005  |   Pubmed ID: 16047260
• Betaine Concentration As a Determinant of Fasting Total Homocysteine Concentrations and the Effect of Folic Acid Supplementation on Betaine Concentrations
  The American Journal of Clinical Nutrition. Jun, 2005  |   Pubmed ID: 15941890
• The P160 Family Coactivators Regulate Breast Cancer Cell Proliferation and Invasion Through Autocrine/paracrine Activity of SDF-1alpha/CXCL12
  Carcinogenesis. Oct, 2005  |   Pubmed ID: 15917309
• Oral Cyanocobalamin Supplementation in Older People with Vitamin B12 Deficiency: a Dose-finding Trial
  Archives of Internal Medicine. May, 2005  |   Pubmed ID: 15911731
• Transforming Learning: the Challenge of Interprofessional Education
  Hospital Medicine (London, England : 1998). Apr, 2005  |   Pubmed ID: 15889874
• The Mammary Gland "side Population": a Putative Stem/progenitor Cell Marker?
  Journal of Mammary Gland Biology and Neoplasia. Jan, 2005  |   Pubmed ID: 15886885
• Stem Cells and Tissue Homeostasis in Mammary Glands
  Journal of Mammary Gland Biology and Neoplasia. Jan, 2005  |   Pubmed ID: 15886881
• Interferon Regulatory Factor-1 (IRF-1) Exhibits Tumor Suppressor Activities in Breast Cancer Associated with Caspase Activation and Induction of Apoptosis
  Carcinogenesis. Sep, 2005  |   Pubmed ID: 15878912
• Role of Toll-like Receptor-4 in Genetic Susceptibility to Lung Injury Induced by Residual Oil Fly Ash
  Physiological Genomics. Jun, 2005  |   Pubmed ID: 15784698
• Common Origins of MDA-MB-435 Cells from Various Sources with Those Shown to Have Melanoma Properties
  Clinical & Experimental Metastasis. 2004  |   Pubmed ID: 15679052
• LCC15-MB Cells Are MDA-MB-435: a Review of Misidentified Breast and Prostate Cell Lines
  Clinical & Experimental Metastasis. 2004  |   Pubmed ID: 15679051
• Homocysteine and Coronary Heart Disease
  Seminars in Vascular Medicine. Nov, 2002  |   Pubmed ID: 16222629
• Cholesterol, Coronary Heart Disease and Stroke: a Review of Published Evidence from Observational Studies and Randomized Controlled Trials
  Seminars in Vascular Medicine. Aug, 2002  |   Pubmed ID: 16222621