Roland Malli Institute of Molecular Biology and Biochemistry Medical University of Graz Biography Publications Institution JoVE Articles Roland Malli has not added a biography. If you are Roland Malli and would like to personalize this page please email our Author Liaison for assistance. Publications Intact Mitochondrial Ca(2+) Uniport is Essential for Agonist-induced Activation of Endothelial Nitric Oxide Synthase (eNOS) Free Radical Biology & Medicine. Jan, 2017 | Pubmed ID: 27923677 Formation of Nitric Oxide by Aldehyde Dehydrogenase-2 Is Necessary and Sufficient for Vascular Bioactivation of Nitroglycerin The Journal of Biological Chemistry. Nov, 2016 | Pubmed ID: 27679490 PRMT1-mediated Methylation of MICU1 Determines the UCP2/3 Dependency of Mitochondrial Ca(2+) Uptake in Immortalized Cells Nature Communications. Sep, 2016 | Pubmed ID: 27642082 Resveratrol Specifically Kills Cancer Cells by a Devastating Increase in the Ca2+ Coupling Between the Greatly Tethered Endoplasmic Reticulum and Mitochondria Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 2016 | Pubmed ID: 27606689 Filling a GAP-An Optimized Probe for ER Ca(2+) Imaging In Vivo Cell Chemical Biology. Jun, 2016 | Pubmed ID: 27341431 Development of Novel FP-based Probes for Live-cell Imaging of Nitric Oxide Dynamics Nature Communications. Feb, 2016 | Pubmed ID: 26842907 Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy (3rd Edition) Autophagy. Jan, 2016 | Pubmed ID: 26799652 Rearrangement of MICU1 Multimers for Activation of MCU is Solely Controlled by Cytosolic Ca(2.) Scientific Reports. Oct, 2015 | Pubmed ID: 26489515 UCP2 Modulates Single-channel Properties of a MCU-dependent Ca(2+) Inward Current in Mitochondria Pflugers Archiv : European Journal of Physiology. Dec, 2015 | Pubmed ID: 26275882 Generation of Red-Shifted Cameleons for Imaging Ca²⁺ Dynamics of the Endoplasmic Reticulum Sensors (Basel, Switzerland). Jun, 2015 | Pubmed ID: 26053751 Assessment of Mitochondrial Ca²⁺ Uptake Methods in Molecular Biology (Clifton, N.J.). 2015 | Pubmed ID: 25631032 Oleoyl-lysophosphatidylcholine Limits Endothelial Nitric Oxide Bioavailability by Induction of Reactive Oxygen Species PloS One. 2014 | Pubmed ID: 25419657 TRPV1 Mediates Cellular Uptake of Anandamide and Thus Promotes Endothelial Cell Proliferation and Network-formation Biology Open. Nov, 2014 | Pubmed ID: 25395667 Characterization of Rat Serum Amyloid A4 (SAA4): a Novel Member of the SAA Superfamily Biochemical and Biophysical Research Communications. Aug, 2014 | Pubmed ID: 25044109 IP3-mediated STIM1 Oligomerization Requires Intact Mitochondrial Ca2+ Uptake Journal of Cell Science. Jul, 2014 | Pubmed ID: 24806964 Adaptations of Energy Metabolism Associated with Increased Levels of Mitochondrial Cholesterol in Niemann-Pick Type C1-deficient Cells The Journal of Biological Chemistry. Jun, 2014 | Pubmed ID: 24790103 ATP Increases Within the Lumen of the Endoplasmic Reticulum Upon Intracellular Ca2+ Release Molecular Biology of the Cell. Feb, 2014 | Pubmed ID: 24307679 Mitochondrial Ca(2+) Uniporter (MCU)-dependent and MCU-independent Ca(2+) Channels Coexist in the Inner Mitochondrial Membrane Pflugers Archiv : European Journal of Physiology. Jul, 2014 | Pubmed ID: 24162235 Molecularly Distinct Routes of Mitochondrial Ca2+ Uptake Are Activated Depending on the Activity of the Sarco/endoplasmic Reticulum Ca2+ ATPase (SERCA) The Journal of Biological Chemistry. May, 2013 | Pubmed ID: 23592775 N-Arachidonoyl Glycine Suppresses Na⁺/Ca²⁺ Exchanger-mediated Ca²⁺ Entry into Endothelial Cells and Activates BK(Ca) Channels Independently of GPCRs British Journal of Pharmacology. Jun, 2013 | Pubmed ID: 23517055 Characterization of Distinct Single-channel Properties of Ca²⁺ Inward Currents in Mitochondria Pflugers Archiv : European Journal of Physiology. Jul, 2013 | Pubmed ID: 23397170 The Endocannabinoid N-arachidonoyl Glycine (NAGly) Inhibits Store-operated Ca2+ Entry by Preventing STIM1-Orai1 Interaction Journal of Cell Science. Feb, 2013 | Pubmed ID: 23239024 Spatiotemporal Correlations Between Cytosolic and Mitochondrial Ca(2+) Signals Using a Novel Red-Shifted Mitochondrial Targeted Cameleon PloS One. 2012 | Pubmed ID: 23029314 Mitochondrial Ca2+ Uptake 1 (MICU1) and Mitochondrial Ca2+ Uniporter (MCU) Contribute to Metabolism-secretion Coupling in Clonal Pancreatic β-cells The Journal of Biological Chemistry. Oct, 2012 | Pubmed ID: 22904319 Acyl Chain-dependent Effect of Lysophosphatidylcholine on Cyclooxygenase (COX)-2 Expression in Endothelial Cells Atherosclerosis. Oct, 2012 | Pubmed ID: 22901457 The Vascular Barrier-protecting Hawthorn Extract WS® 1442 Raises Endothelial Calcium Levels by Inhibition of SERCA and Activation of the IP3 Pathway Journal of Molecular and Cellular Cardiology. Oct, 2012 | Pubmed ID: 22814436 Inhibition of Autophagy Rescues Palmitic Acid-induced Necroptosis of Endothelial Cells The Journal of Biological Chemistry. Jun, 2012 | Pubmed ID: 22556413 Mutation in NSUN2, Which Encodes an RNA Methyltransferase, Causes Autosomal-recessive Intellectual Disability American Journal of Human Genetics. May, 2012 | Pubmed ID: 22541562 Docosahexaenoic Acid-induced Unfolded Protein Response, Cell Cycle Arrest, and Apoptosis in Vascular Smooth Muscle Cells Are Triggered by Ca²⁺-dependent Induction of Oxidative Stress Free Radical Biology & Medicine. May, 2012 | Pubmed ID: 22391221 Endothelial Mitochondria--less Respiration, More Integration Pflugers Archiv : European Journal of Physiology. Jul, 2012 | Pubmed ID: 22382745 Studying Mitochondrial Ca(2+) Uptake - a Revisit Molecular and Cellular Endocrinology. Apr, 2012 | Pubmed ID: 22100614 Leucine Zipper EF Hand-containing Transmembrane Protein 1 (Letm1) and Uncoupling Proteins 2 and 3 (UCP2/3) Contribute to Two Distinct Mitochondrial Ca2+ Uptake Pathways The Journal of Biological Chemistry. Aug, 2011 | Pubmed ID: 21613221 The GPR55 Agonist Lysophosphatidylinositol Directly Activates Intermediate-conductance Ca2+ -activated K+ Channels Pflugers Archiv : European Journal of Physiology. Aug, 2011 | Pubmed ID: 21603896 Sequential Synthesis and Methylation of Phosphatidylethanolamine Promote Lipid Droplet Biosynthesis and Stability in Tissue Culture and in Vivo The Journal of Biological Chemistry. May, 2011 | Pubmed ID: 21454708 Triacylglycerol Accumulation Activates the Mitochondrial Apoptosis Pathway in Macrophages The Journal of Biological Chemistry. Mar, 2011 | Pubmed ID: 21196579 Uncoupling Protein 3 Adjusts Mitochondrial Ca(2+) Uptake to High and Low Ca(2+) Signals Cell Calcium. Nov, 2010 | Pubmed ID: 21047682 GPR55-dependent and -independent Ion Signalling in Response to Lysophosphatidylinositol in Endothelial Cells British Journal of Pharmacology. Sep, 2010 | Pubmed ID: 20735417 Acyl Chain-dependent Effect of Lysophosphatidylcholine on Endothelial Prostacyclin Production Journal of Lipid Research. Oct, 2010 | Pubmed ID: 20610733 Mitochondrial Ca2+ Uptake and Not Mitochondrial Motility is Required for STIM1-Orai1-dependent Store-operated Ca2+ Entry Journal of Cell Science. Aug, 2010 | Pubmed ID: 20587595 The Contribution of UCP2 and UCP3 to Mitochondrial Ca(2+) Uptake is Differentially Determined by the Source of Supplied Ca(2+) Cell Calcium. May, 2010 | Pubmed ID: 20403634 Vesicular Calcium Regulates Coat Retention, Fusogenicity, and Size of Pre-Golgi Intermediates Molecular Biology of the Cell. Mar, 2010 | Pubmed ID: 20089833 Mitochondrial Ca2+ Channels: Great Unknowns with Important Functions FEBS Letters. May, 2010 | Pubmed ID: 20074570 Lysophosphatidic Acid Receptor Activation Affects the C13NJ Microglia Cell Line Proteome Leading to Alterations in Glycolysis, Motility, and Cytoskeletal Architecture Proteomics. Jan, 2010 | Pubmed ID: 19899077 Mitochondrial Protein Phosphorylation: Instigator or Target of Lipotoxicity? Trends in Endocrinology and Metabolism: TEM. May, 2009 | Pubmed ID: 19356948 Cytosolic Ca2+ Prevents the Subplasmalemmal Clustering of STIM1: an Intrinsic Mechanism to Avoid Ca2+ Overload Journal of Cell Science. Oct, 2008 | Pubmed ID: 18765567 Integrin Clustering Enables Anandamide-induced Ca2+ Signaling in Endothelial Cells Via GPR55 by Protection Against CB1-receptor-triggered Repression Journal of Cell Science. May, 2008 | Pubmed ID: 18445684 The C-terminal Region of Human Adipose Triglyceride Lipase Affects Enzyme Activity and Lipid Droplet Binding The Journal of Biological Chemistry. Jun, 2008 | Pubmed ID: 18445597 Mitochondrial Ca2+, the Secret Behind the Function of Uncoupling Proteins 2 and 3? Cell Calcium. Jul, 2008 | Pubmed ID: 18282596 Mitochondria and Ca(2+) Signaling: Old Guests, New Functions Pflugers Archiv : European Journal of Physiology. Dec, 2007 | Pubmed ID: 17611770 Uncoupling Proteins 2 and 3 Are Fundamental for Mitochondrial Ca2+ Uniport Nature Cell Biology. Apr, 2007 | Pubmed ID: 17351641 Mg2+ Deprivation Elicits Rapid Ca2+ Uptake and Activates Ca2+/calcineurin Signaling in Saccharomyces Cerevisiae Eukaryotic Cell. Apr, 2007 | Pubmed ID: 17337637 Mitochondria Maintain Maturation and Secretion of Lipoprotein Lipase in the Endoplasmic Reticulum The Biochemical Journal. May, 2006 | Pubmed ID: 16466345 A New Type of Non-Ca2+-buffering Apo(a)-based Fluorescent Indicator for Intraluminal Ca2+ in the Endoplasmic Reticulum The Journal of Biological Chemistry. Feb, 2006 | Pubmed ID: 16368693 Twenty Years of Calcium Imaging: Cell Physiology to Dye For Molecular Interventions. Apr, 2005 | Pubmed ID: 15821159 Hyperglycemic Conditions Affect Shape and Ca2+ Homeostasis of Mitochondria in Endothelial Cells Journal of Cardiovascular Pharmacology. Oct, 2004 | Pubmed ID: 15454850 Kisspeptin-10, a KiSS-1/metastin-derived Decapeptide, is a Physiological Invasion Inhibitor of Primary Human Trophoblasts Journal of Cell Science. Mar, 2004 | Pubmed ID: 15020672 Heterozygous Missense Mutations in BSCL2 Are Associated with Distal Hereditary Motor Neuropathy and Silver Syndrome Nature Genetics. Mar, 2004 | Pubmed ID: 14981520 Anandamide Initiates Ca(2+) Signaling Via CB2 Receptor Linked to Phospholipase C in Calf Pulmonary Endothelial Cells British Journal of Pharmacology. Dec, 2003 | Pubmed ID: 14645143 Sustained Ca2+ Transfer Across Mitochondria is Essential for Mitochondrial Ca2+ Buffering, Sore-operated Ca2+ Entry, and Ca2+ Store Refilling The Journal of Biological Chemistry. Nov, 2003 | Pubmed ID: 12941956 Mitochondria Efficiently Buffer Subplasmalemmal Ca2+ Elevation During Agonist Stimulation The Journal of Biological Chemistry. Mar, 2003 | Pubmed ID: 12529366 Novel High Energy Intermediate Analogues with Triazasterol-related Structures As Inhibitors of Ergosterol Biosynthesis. Part I: Synthesis and Antifungal Activity of N-alkyl-N'-(phenethyl- and Cyclohexenylethyl)guanidines and N2-substituted 2-imidazolinamines Archiv Der Pharmazie. 2002 | Pubmed ID: 12596218 Nitric Oxide Inhibits Capacitative Ca2+ Entry by Suppression of Mitochondrial Ca2+ Handling British Journal of Pharmacology. Nov, 2002 | Pubmed ID: 12411413 Functional Analysis of Histamine Receptor Subtypes Involved in Endothelium-mediated Relaxation of the Human Uterine Artery Clinical and Experimental Pharmacology & Physiology. Aug, 2002 | Pubmed ID: 12100006 Subplasmalemmal Endoplasmic Reticulum Controls K(Ca) Channel Activity Upon Stimulation with a Moderate Histamine Concentration in a Human Umbilical Vein Endothelial Cell Line The Journal of Physiology. Apr, 2002 | Pubmed ID: 11927670 Tissue-specific Expression of Human Lipoprotein Lipase in the Vascular System Affects Vascular Reactivity in Transgenic Mice British Journal of Pharmacology. Jan, 2002 | Pubmed ID: 11786490 Oxidized Phospholipids Stimulate Tissue Factor Expression in Human Endothelial Cells Via Activation of ERK/EGR-1 and Ca(++)/NFAT Blood. Jan, 2002 | Pubmed ID: 11756172 आनुवंशिक रूप से इनकोडिंग फ्लोरोसेंट नाइट्रिक ऑक्साइड का आवेदन (सं •) जांच, geNOps, एकल कक्षों में सं • सिग्नल की वास्तविक समय इमेजिंग के लिए Emrah Eroglu1, Rene Rost1, Helmut Bischof1, Sandra Blass1, Anna Schreilechner1, Benjamin Gottschalk1, Maria R. Depaoli1, Christiane Klec1, Suphachai Charoensin1, Corina T. Madreiter-Sokolowski1, Jeta Ramadani1, Markus Waldeck-Weiermair1, Wolfgang F. Graier1, Roland Malli1 1Institute of Molecular Biology and Biochemistry, Medical University of Graz Biology
आनुवंशिक रूप से इनकोडिंग फ्लोरोसेंट नाइट्रिक ऑक्साइड का आवेदन (सं •) जांच, geNOps, एकल कक्षों में सं • सिग्नल की वास्तविक समय इमेजिंग के लिए Emrah Eroglu1, Rene Rost1, Helmut Bischof1, Sandra Blass1, Anna Schreilechner1, Benjamin Gottschalk1, Maria R. Depaoli1, Christiane Klec1, Suphachai Charoensin1, Corina T. Madreiter-Sokolowski1, Jeta Ramadani1, Markus Waldeck-Weiermair1, Wolfgang F. Graier1, Roland Malli1 1Institute of Molecular Biology and Biochemistry, Medical University of Graz Biology
