Rolf M.F. Berger

Publications

• GDF-15 (Growth Differentiation Factor 15) Is Associated With Hospitalization and Mortality in Patients With a Fontan Circulation
  Journal of the American Heart Association. May, 2020  |   Pubmed ID: 32384007
• Onset of Brain Injury in Infants with Prenatally Diagnosed Congenital Heart Disease
  PloS One. 2020  |   Pubmed ID: 32210445
• TBX4 Variants and Pulmonary Diseases: Getting out of the 'Box'
  Current Opinion in Pulmonary Medicine. May, 2020  |   Pubmed ID: 32195678
• Serial Measurements of N-Terminal Pro-B-Type Natriuretic Peptide Serum Level for Monitoring Pulmonary Arterial Hypertension in Children
  The Journal of Pediatrics. May, 2020  |   Pubmed ID: 32113658
• Early Angiogenic Proteins Associated with High Risk for Bronchopulmonary Dysplasia and Pulmonary Hypertension in Preterm Infants
  American Journal of Physiology. Lung Cellular and Molecular Physiology. Apr, 2020  |   Pubmed ID: 31967847
• Serial Cardiovascular Magnetic Resonance Feature Tracking Indicates Early Worsening of Cardiac Function in Fontan Patients
  International Journal of Cardiology. 03, 2020  |   Pubmed ID: 31918854
• Setting the Stage for Increasing Diversity in Congenital Cardiology: Let's Celebrate the 75th Anniversary of the Blalock-Thomas-Taussig Shunt
  Cardiology in the Young. Mar, 2020  |   Pubmed ID: 31910925
• Reply to Ning : More Insights into the Association Between RVX-208 and Pulmonary Arterial Hypertension
  American Journal of Respiratory and Critical Care Medicine. 02, 2020  |   Pubmed ID: 31560564
• Thoracotomy Versus Sternotomy for Patent Ductus Arteriosus Closure in Preterm Neonates
  The Annals of Thoracic Surgery. 01, 2020  |   Pubmed ID: 31408645
• Metabolic Remodeling in the Pressure-Loaded Right Ventricle: Shifts in Glucose and Fatty Acid Metabolism-A Systematic Review and Meta-Analysis
  Journal of the American Heart Association. 11, 2019  |   Pubmed ID: 31657265
• Recommendations from the Association for European Paediatric and Congenital Cardiology for Training in Pulmonary Hypertension
  Cardiology in the Young. Nov, 2019  |   Pubmed ID: 31554525
• Failing Homeostasis of Quadriceps Muscle Energy- and PH Balance During Bicycling in a Young Patient With a Fontan Circulation
  Frontiers in Cardiovascular Medicine. 2019  |   Pubmed ID: 31497605
• The Ever-expanding Phenotypical Spectrum of Human TBX4 Mutations: from Toe to Lung
  The European Respiratory Journal. Aug, 2019  |   Pubmed ID: 31439725
• Reply to Piquereau and Perros and to Pullamsetti and De Jesus Perez
  American Journal of Respiratory and Critical Care Medicine. 11, 2019  |   Pubmed ID: 31419387
• CMR Feature Tracking Left Ventricular Strain-rate Predicts Ventricular Tachyarrhythmia, but Not Deterioration of Ventricular Function in Patients with Repaired Tetralogy of Fallot
  International Journal of Cardiology. 11, 2019  |   Pubmed ID: 31402156
• New Strategies for the Conduct of Clinical Trials in Pediatric Pulmonary Arterial Hypertension: Outcome of a Multistakeholder Meeting With Patients, Academia, Industry, and Regulators, Held at the European Medicines Agency on Monday, June 12, 2017
  Journal of the American Heart Association. 05, 2019  |   Pubmed ID: 31088189
• Meaningful and Feasible Composite Clinical Worsening Definitions in Paediatric Pulmonary Arterial Hypertension: An Analysis of the TOPP Registry
  International Journal of Cardiology. 08, 2019  |   Pubmed ID: 31072635
• Multicenter Preclinical Validation of BET Inhibition for the Treatment of Pulmonary Arterial Hypertension
  American Journal of Respiratory and Critical Care Medicine. 10, 2019  |   Pubmed ID: 31042405
• A Novel Method Optimizing the Normalization of Cardiac Parameters in Small Animal Models: the Importance of Dimensional Indexing
  American Journal of Physiology. Heart and Circulatory Physiology. 06, 2019  |   Pubmed ID: 30978120
• The Natural and Unnatural History of Congenital Aortic Arch Abnormalities Evaluated in an Adult Survival Cohort
  The Canadian Journal of Cardiology. 04, 2019  |   Pubmed ID: 30935634
• Response: Still Puzzling About a Clear Definition of Pulmonary Arterial Hypertension in Newborns
  The European Respiratory Journal. Mar, 2019  |   Pubmed ID: 30923178
• Converging Paths of Pulmonary Arterial Hypertension and Cellular Senescence
  American Journal of Respiratory Cell and Molecular Biology. 07, 2019  |   Pubmed ID: 30758225
• The Janus-faced Fontan Circulation: Unravelling Its Elusive Pathophysiology
  European Journal of Heart Failure. 06, 2019  |   Pubmed ID: 30730092
• Early Diagnosis in Pulmonary Arterial Hypertension: The Search for the Holy Grail
  American Journal of Respiratory and Critical Care Medicine. Jun, 2019  |   Pubmed ID: 30649901
• Paediatric Pulmonary Arterial Hypertension: Updates on Definition, Classification, Diagnostics and Management
  The European Respiratory Journal. Jan, 2019  |   Pubmed ID: 30545978
• Assessment of Reversibility in Pulmonary Arterial Hypertension and Congenital Heart Disease
  Heart (British Cardiac Society). 02, 2019  |   Pubmed ID: 30467194
• Risk of Cardiac Tachyarrhythmia in Patients with Repaired Tetralogy of Fallot: a Multicenter Cardiac MRI Based Study
  The International Journal of Cardiovascular Imaging. Jan, 2019  |   Pubmed ID: 30094564
• Pulmonary Vasodilator Therapy As Treatment for Patients with a Fontan Circulation: the Emperor's New Clothes?
  Pulmonary Circulation. Oct-Dec, 2018  |   Pubmed ID: 30338725
• Quality of Life and Sexual Well-being in Patients with a Fontan Circulation: An Explorative Pilot Study with a Mixed Method Design
  Congenital Heart Disease. Mar, 2018  |   Pubmed ID: 29532606
• Identification of Gaps in the Current Knowledge on Pulmonary Hypertension in Extremely Preterm Infants: A Systematic Review and Meta-analysis
  Paediatric and Perinatal Epidemiology. 05, 2018  |   Pubmed ID: 29341209
• Amplitude-integrated Electroencephalography During the First 72 h After Birth in Neonates Diagnosed Prenatally with Congenital Heart Disease
  Pediatric Research. 04, 2018  |   Pubmed ID: 29244798
• Volume Load-induced Right Ventricular Dysfunction in Animal Models: Insights in a Translational Gap in Congenital Heart Disease
  European Journal of Heart Failure. 04, 2018  |   Pubmed ID: 28925007
• Right Ventricular-vascular Coupling in Heart Failure with Preserved Ejection Fraction and Pre- Vs. Post-capillary Pulmonary Hypertension
  European Heart Journal Cardiovascular Imaging. 04, 2018  |   Pubmed ID: 28531295
• Pulmonary Arterial Stiffness Indices Assessed by Intravascular Ultrasound in Children with Early Pulmonary Vascular Disease: Prediction of Advanced Disease and Mortality During 20-year Follow-up
  European Heart Journal Cardiovascular Imaging. 02, 2018  |   Pubmed ID: 28329155
• Cerebral and Renal Oxygen Saturation Are Not Compromised in the Presence of Retrograde Blood Flow in Either the Ascending or Descending Aorta in Term or Near-Term Infants with Left-Sided Obstructive Lesions
  Neonatology. 2017  |   Pubmed ID: 28704832
• Prenatal Exposure to Serotonin Reuptake Inhibitors and Congenital Heart Anomalies: an Exploratory Pharmacogenetics Study
  Pharmacogenomics. Jul, 2017  |   Pubmed ID: 28639488
• Fontan Circulation over Time
  The American Journal of Cardiology. Aug, 2017  |   Pubmed ID: 28624095
• Pediatric Pulmonary Arterial Hypertension: on the Eve of Growing Up
  Current Opinion in Pulmonary Medicine. 09, 2017  |   Pubmed ID: 28590293
• Diagnostic Value of Doppler Echocardiography for Identifying Hemodynamic Significant Pulmonary Valve Regurgitation in Tetralogy of Fallot: Comparison with Cardiac MRI
  The International Journal of Cardiovascular Imaging. Nov, 2017  |   Pubmed ID: 28567705
• Pulmonary Arterial Hypertension in Congenital Heart Disease: Translational Opportunities to Study the Reversibility of Pulmonary Vascular Disease
  European Heart Journal. Jul, 2017  |   Pubmed ID: 28369399
• Right Ventricular Recovery After Bilateral Lung Transplantation for Pulmonary Arterial Hypertension†
  Interactive Cardiovascular and Thoracic Surgery. 06, 2017  |   Pubmed ID: 28329267
• Diminished Liver Microperfusion in Fontan Patients: A Biexponential DWI Study
  PloS One. 2017  |   Pubmed ID: 28257439
• A Bosentan Pharmacokinetic Study to Investigate Dosing Regimens in Paediatric Patients with Pulmonary Arterial Hypertension: FUTURE-3
  British Journal of Clinical Pharmacology. 08, 2017  |   Pubmed ID: 28213957
• Physical Activity in Pediatric Pulmonary Arterial Hypertension Measured by Accelerometry. A Candidate Clinical Endpoint
  American Journal of Respiratory and Critical Care Medicine. 07, 2017  |   Pubmed ID: 28178426
• Serially Measured Uric Acid Levels Predict Disease Severity and Outcome in Pediatric Pulmonary Arterial Hypertension
  American Journal of Respiratory and Critical Care Medicine. Feb, 2017  |   Pubmed ID: 28145758
• Effects of Sildenafil on Cardiac Structure and Function, Cardiopulmonary Exercise Testing and Health-related Quality of Life Measures in Heart Failure Patients with Preserved Ejection Fraction and Pulmonary Hypertension
  European Journal of Heart Failure. Jan, 2017  |   Pubmed ID: 27873388
• Clinical Classification in Pediatric Pulmonary Arterial Hypertension Associated with Congenital Heart Disease
  Pulmonary Circulation. Sep, 2016  |   Pubmed ID: 27683607
• Corrigendum to "FUTURE-2: Results from an Open-label, Long-term Safety and Tolerability Extension Study Using the Pediatric FormUlation of BosenTan in PUlmonary Arterial HypeRtEnsion" [Int. J. Cardiol. 202 (2016) 52-58]
  International Journal of Cardiology. Nov, 2016  |   Pubmed ID: 27623401
• Multisite Tissue Oxygenation Monitoring Indicates Organ-Specific Flow Distribution and Oxygen Delivery Related to Low Cardiac Output in Preterm Infants With Clinical Sepsis
  Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. Aug, 2016  |   Pubmed ID: 27500612
• Renal Thrombotic Microangiopathy in Patients with CblC Defect: Review of an Under-recognized Entity
  Pediatric Nephrology (Berlin, Germany). Jun, 2016  |   Pubmed ID: 27289364
• A Hemodynamically Significant Patent Ductus Arteriosus Does Not Affect Cerebral or Renal Tissue Oxygenation in Preterm Infants
  Neonatology. 2016  |   Pubmed ID: 27088709
• Surgical Options After Fontan Failure
  Heart (British Cardiac Society). Jul, 2016  |   Pubmed ID: 27076374
• Growth in Children with Pulmonary Arterial Hypertension: a Longitudinal Retrospective Multiregistry Study
  The Lancet. Respiratory Medicine. Apr, 2016  |   Pubmed ID: 26994897
• Acute Vasodilator Response in Pediatric Pulmonary Arterial Hypertension: Current Clinical Practice From the TOPP Registry
  Journal of the American College of Cardiology. Mar, 2016  |   Pubmed ID: 26988953
• Common Arterial Trunk and Ventricular Non-compaction in Lrp2 Knockout Mice Indicate a Crucial Role of LRP2 in Cardiac Development
  Disease Models & Mechanisms. Apr, 2016  |   Pubmed ID: 26822476
• Cardiovascular Malformations Caused by NOTCH1 Mutations Do Not Keep Left: Data on 428 Probands with Left-sided CHD and Their Families
  Genetics in Medicine : Official Journal of the American College of Medical Genetics. Sep, 2016  |   Pubmed ID: 26820064
• Egr-1 Identifies Neointimal Remodeling and Relates to Progression in Human Pulmonary Arterial Hypertension
  The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. Apr, 2016  |   Pubmed ID: 26774383
• The Fontan Circulation and the Liver: A Magnetic Resonance Diffusion-weighted Imaging Study
  International Journal of Cardiology. Jan, 2016  |   Pubmed ID: 26447669
• FUTURE-2: Results from an Open-label, Long-term Safety and Tolerability Extension Study Using the Pediatric FormUlation of BosenTan in PUlmonary Arterial HypeRtEnsion
  International Journal of Cardiology. Jan, 2016  |   Pubmed ID: 26386921
• Six-minute Walking Distance and Decrease in Oxygen Saturation During the Six-minute Walk Test in Pediatric Pulmonary Arterial Hypertension
  International Journal of Cardiology. Jan, 2016  |   Pubmed ID: 26386916
• Erythropoietin Attenuates Pulmonary Vascular Remodeling in Experimental Pulmonary Arterial Hypertension Through Interplay Between Endothelial Progenitor Cells and Heme Oxygenase
  Frontiers in Pediatrics. 2015  |   Pubmed ID: 26380246
• Effects of Sildenafil on Invasive Haemodynamics and Exercise Capacity in Heart Failure Patients with Preserved Ejection Fraction and Pulmonary Hypertension: a Randomized Controlled Trial
  European Heart Journal. Oct, 2015  |   Pubmed ID: 26188003
• Ductus Arteriosus Aneurysm and Vocal Cord Paralysis
  Circulation. May, 2015  |   Pubmed ID: 25964282
• Pulmonary Regurgitant Volume is Superior to Fraction Using Background-corrected Phase Contrast MRI in Determining the Severity of Regurgitation in Repaired Tetralogy of Fallot
  The International Journal of Cardiovascular Imaging. Aug, 2015  |   Pubmed ID: 25944487
• Adverse Pulmonary Vascular Remodeling in the Fontan Circulation
  The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. Mar, 2015  |   Pubmed ID: 25813767
• Right Ventricular Failure Due to Chronic Pressure Load: What Have We Learned in Animal Models Since the NIH Working Group Statement?
  Heart Failure Reviews. Jul, 2015  |   Pubmed ID: 25771982
• Clinical Worsening As Composite Study End Point in Pediatric Pulmonary Arterial Hypertension
  Chest. Sep, 2015  |   Pubmed ID: 25741884
• What's the (end) Point?
  The European Respiratory Journal. Mar, 2015  |   Pubmed ID: 25726540
• Prognostic Factors in Pediatric Pulmonary Arterial Hypertension: A Systematic Review and Meta-analysis
  International Journal of Cardiology. Apr, 2015  |   Pubmed ID: 25706327
• Echocardiography in Pediatric Pulmonary Arterial Hypertension: Early Study on Assessing Disease Severity and Predicting Outcome
  Circulation. Cardiovascular Imaging. Jan, 2015  |   Pubmed ID: 25552488
• Clinical Symptoms of Right Ventricular Failure in Experimental Chronic Pressure Load Are Associated with Progressive Diastolic Dysfunction
  Journal of Molecular and Cellular Cardiology. Feb, 2015  |   Pubmed ID: 25486580
• The Challenges in Paediatric Pulmonary Arterial Hypertension
  European Respiratory Review : an Official Journal of the European Respiratory Society. Dec, 2014  |   Pubmed ID: 25445948
• Current and Advancing Treatments for Pulmonary Arterial Hypertension in Childhood
  Expert Review of Respiratory Medicine. Oct, 2014  |   Pubmed ID: 25047735
• Identification of Treatment Goals in Paediatric Pulmonary Arterial Hypertension
  The European Respiratory Journal. Dec, 2014  |   Pubmed ID: 25034572
• A Critical Role for Egr-1 During Vascular Remodelling in Pulmonary Arterial Hypertension
  Cardiovascular Research. Sep, 2014  |   Pubmed ID: 25028387
• Sildenafil Treatment in Established Right Ventricular Dysfunction Improves Diastolic Function and Attenuates Interstitial Fibrosis Independent from Afterload
  American Journal of Physiology. Heart and Circulatory Physiology. Aug, 2014  |   Pubmed ID: 24878769
• Pulmonary Hypertension: Smaller Kids, Smaller Steps
  The Lancet. Respiratory Medicine. May, 2014  |   Pubmed ID: 24815801
• Ventricular Remodelling After Pulmonary Valve Replacement: Comparison Between Pressure-loaded and Volume-loaded Right Ventricles
  Interactive Cardiovascular and Thoracic Surgery. Jul, 2014  |   Pubmed ID: 24722515
• Survival Differences in Pediatric Pulmonary Arterial Hypertension: Clues to a Better Understanding of Outcome and Optimal Treatment Strategies
  Journal of the American College of Cardiology. May, 2014  |   Pubmed ID: 24681143
• Effect of Right Ventricular Outflow Tract Obstruction on Right Ventricular Volumes and Exercise Capacity in Patients with Repaired Tetralogy of Fallot
  The American Journal of Cardiology. Feb, 2014  |   Pubmed ID: 24355311
• Pediatric Pulmonary Hypertension
  Journal of the American College of Cardiology. Dec, 2013  |   Pubmed ID: 24355636
• A Cornerstone of Heart Failure Treatment is Not Effective in Experimental Right Ventricular Failure
  International Journal of Cardiology. Nov, 2013  |   Pubmed ID: 24067600
• Frequency and Prognostic Significance of Hemoptysis in Pediatric Pulmonary Arterial Hypertension
  The American Journal of Cardiology. Nov, 2013  |   Pubmed ID: 23972345
• Combined Pulmonary Hypertension and Renal Thrombotic Microangiopathy in Cobalamin C Deficiency
  Pediatrics. Aug, 2013  |   Pubmed ID: 23837176
• The Role of Disturbed Blood Flow in the Development of Pulmonary Arterial Hypertension: Lessons from Preclinical Animal Models
  American Journal of Physiology. Lung Cellular and Molecular Physiology. Jul, 2013  |   Pubmed ID: 23624788
• TBX4 Mutations (small Patella Syndrome) Are Associated with Childhood-onset Pulmonary Arterial Hypertension
  Journal of Medical Genetics. Aug, 2013  |   Pubmed ID: 23592887
• Pulsatile Haemodynamic Parameters Are Predictors of Survival in Paediatric Pulmonary Arterial Hypertension
  International Journal of Cardiology. Sep, 2013  |   Pubmed ID: 23340486
• The Role of Maternal-fetal Cholesterol Transport in Early Fetal Life: Current Insights
  Biology of Reproduction. Jan, 2013  |   Pubmed ID: 23153566
• Effect of Balloon Atrial Septostomy on Cerebral Oxygenation in Neonates with Transposition of the Great Arteries
  Pediatric Research. Jan, 2013  |   Pubmed ID: 23095977
• Physiological Interaction of Heart and Lung in Thoracic Irradiation
  International Journal of Radiation Oncology, Biology, Physics. Dec, 2012  |   Pubmed ID: 22975617
• Sildenafil Enhances Systolic Adaptation, but Does Not Prevent Diastolic Dysfunction, in the Pressure-loaded Right Ventricle
  European Journal of Heart Failure. Sep, 2012  |   Pubmed ID: 22730335
• The Origin of Fetal Sterols in Second-trimester Amniotic Fluid: Endogenous Synthesis or Maternal-fetal Transport?
  American Journal of Obstetrics and Gynecology. Sep, 2012  |   Pubmed ID: 22728028
• Clinical Features of Paediatric Pulmonary Hypertension: a Registry Study
  Lancet (London, England). Feb, 2012  |   Pubmed ID: 22240409
• Pediatric Pulmonary Hypertension in the Netherlands: Epidemiology and Characterization During the Period 1991 to 2005
  Circulation. Oct, 2011  |   Pubmed ID: 21947294
• Egr-1 Expression During Neointimal Development in Flow-associated Pulmonary Hypertension
  The American Journal of Pathology. Nov, 2011  |   Pubmed ID: 21924231
• Acute Pulmonary Vasodilator Response in Paediatric and Adult Pulmonary Arterial Hypertension: Occurrence and Prognostic Value when Comparing Three Response Criteria
  European Heart Journal. Dec, 2011  |   Pubmed ID: 21893489
• Atrial Septal Defects Versus Ventricular Septal Defects in BREATHE-5, a Placebo-controlled Study of Pulmonary Arterial Hypertension Related to Eisenmenger's Syndrome: a Subgroup Analysis
  International Journal of Cardiology. Oct, 2010  |   Pubmed ID: 19464064
• Pulmonary Vascular Remodeling in Congenital Heart Disease: Enhanced Expression of Heat Shock Proteins
  Indian Journal of Biochemistry & Biophysics. Dec, 2009  |   Pubmed ID: 20361711
• Pulse Densitometer Indocyanine Green Dilution Curves: a Simple Applicable and Accurate Method for Determination of Cardiac Shunts
  Congenital Heart Disease. Sep-Oct, 2009  |   Pubmed ID: 19740191
• Clinical Characterization of Pediatric Pulmonary Hypertension: Complex Presentation and Diagnosis
  The Journal of Pediatrics. Aug, 2009  |   Pubmed ID: 19524254
• Low Complication Rates with Totally Implantable Access Port Use in Epoprostenol Treatment of Pulmonary Hypertension
  The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. Mar, 2009  |   Pubmed ID: 19285620
• Biological Serum Markers in the Management of Pediatric Pulmonary Arterial Hypertension
  Pediatric Research. Mar, 2008  |   Pubmed ID: 18287971
• Drug Management of Fetal Tachyarrhythmias: Are We Ready for a Systematic and Evidence-based Approach?
  Pacing and Clinical Electrophysiology : PACE. Feb, 2008  |   Pubmed ID: 18226038
• Pulmonary Arterial Hypertension in Congenital Cardiac Disease--the Need for Refinement of the Evian-Venice Classification
  Cardiology in the Young. Feb, 2008  |   Pubmed ID: 18205971
• Down Syndrome and Aberrant Right Subclavian Artery
  European Journal of Pediatrics. Sep, 2008  |   Pubmed ID: 18172685
• Severe Pregnancy-induced Deterioration of Truncal Valve Regurgitation in an Adolescent Patient with Repaired Truncus Arteriosus
  Cardiology. 2008  |   Pubmed ID: 17726319
• Long-term Effect of Bosentan in Adults Versus Children with Pulmonary Arterial Hypertension Associated with Systemic-to-pulmonary Shunt: Does the Beneficial Effect Persist?
  American Heart Journal. Oct, 2007  |   Pubmed ID: 17893008
• Treprostinil in Advanced Experimental Pulmonary Hypertension: Beneficial Outcome Without Reversed Pulmonary Vascular Remodeling
  Journal of Cardiovascular Pharmacology. Nov, 2006  |   Pubmed ID: 17110807
• Prostacyclin Therapy Increases Right Ventricular Capillarisation in a Model for Flow-associated Pulmonary Hypertension
  European Journal of Pharmacology. Nov, 2006  |   Pubmed ID: 16978602