Sándor J. Kovács Department of Medicine, Cardiovascular Division Washington University in St. Louis Biography Publications Institution JoVE Articles Sándor J. Kovács has not added a biography. If you are Sándor J. Kovács and would like to personalize this page please email our Author Liaison for assistance. Publications Fractionating E-wave Deceleration Time into Its Stiffness and Relaxation Components Distinguishes Pseudonormal from Normal Filling Circulation. Cardiovascular Imaging. Jan, 2015 | Pubmed ID: 25596141 E-wave Generated Intraventricular Diastolic Vortex to L-wave Relation: Model-based Prediction with in Vivo Validation Journal of Applied Physiology (Bethesda, Md. : 1985). Aug, 2014 | Pubmed ID: 24903922 The Isovolumic Relaxation to Early Rapid Filling Relation: Kinematic Model Based Prediction with in Vivo Validation Physiological Reports. 2014 | Pubmed ID: 24760512 The Vortex Formation Time to Diastolic Function Relation: Assessment of Pseudonormalized Versus Normal Filling Physiological Reports. Nov, 2013 | Pubmed ID: 24400169 The Quest for Load-independent Left Ventricular Chamber Properties: Exploring the Normalized Pressure Phase Plane Physiological Reports. Aug, 2013 | Pubmed ID: 24303128 Low-Sodium DASH Diet Improves Diastolic Function and Ventricular-Arterial Coupling in Hypertensive Heart Failure with Preserved Ejection Fraction Circulation. Heart Failure. Aug, 2013 | Pubmed ID: 23985432 Early Left Ventricular Diastolic Function Quantitation Using Directional Impedances Annals of Biomedical Engineering. Jun, 2013 | Pubmed ID: 23370721 Quantitative Assessment of Left Ventricular Diastolic Function Via Longitudinal and Transverse Flow Impedances Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference. 2012 | Pubmed ID: 23367197 Vortex Ring Formation in the Left Ventricle of the Heart: Analysis by 4D Flow MRI and Lagrangian Coherent Structures Annals of Biomedical Engineering. Dec, 2012 | Pubmed ID: 22805980 Spatio-temporal Attributes of Left Ventricular Pressure Decay Rate During Isovolumic Relaxation American Journal of Physiology. Heart and Circulatory Physiology. Mar, 2012 | Pubmed ID: 22210748 Kinematic Modeling-based Left Ventricular Diastatic (passive) Chamber Stiffness Determination with In-vivo Validation Annals of Biomedical Engineering. May, 2012 | Pubmed ID: 22065203 The Diastolic Function to Cyclic Variation of Myocardial Ultrasonic Backscatter Relation: the Influence of Parameterized Diastolic Filling (PDF) Formalism Determined Chamber Properties Ultrasound in Medicine & Biology. Aug, 2011 | Pubmed ID: 21683506 How the (pediatric) Heart Works when It Contracts Application of Left Ventricular "isovolumic Acceleration" As a Load-independent Index of Contractility Journal of the American College of Cardiology. Mar, 2011 | Pubmed ID: 21349403 The Thermodynamics of Diastole: Kinematic Modeling-based Derivation of the P-V Loop to Transmitral Flow Energy Relation with in Vivo Validation American Journal of Physiology. Heart and Circulatory Physiology. Feb, 2011 | Pubmed ID: 21076022 Vortex Formation Time-to-left Ventricular Early Rapid Filling Relation: Model-based Prediction with Echocardiographic Validation Journal of Applied Physiology (Bethesda, Md. : 1985). Dec, 2010 | Pubmed ID: 20864560 Last Word on Point: Counterpoint: Left Ventricular Volume During Diastasis is the Physiological in Vivo Equilibrium Volume and is Related to Diastolic Suction Journal of Applied Physiology (Bethesda, Md. : 1985). Aug, 2010 | Pubmed ID: 20697138 The E-wave Delayed Relaxation Pattern to LV Pressure Contour Relation: Model-based Prediction with in Vivo Validation Ultrasound in Medicine & Biology. Mar, 2010 | Pubmed ID: 20172449 Point: Left Ventricular Volume During Diastasis is the Physiological in Vivo Equilibrium Volume and is Related to Diastolic Suction Journal of Applied Physiology (Bethesda, Md. : 1985). Aug, 2010 | Pubmed ID: 20035061 Solution of the 'inverse Problem of Diastole' Via Kinematic Modeling Allows Determination of Ventricular Properties and Provides Mechanistic Insights into Diastolic Heart Failure Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference. 2009 | Pubmed ID: 19965185 Automated Method for Calculation of a Load-independent Index of Isovolumic Pressure Decay from Left Ventricular Pressure Data Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference. 2009 | Pubmed ID: 19964279 Determination of Early Diastolic LV Vortex Formation Time (T*) Via the PDF Formalism: a Kinematic Model of Filling Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference. 2009 | Pubmed ID: 19964049 The Pressure Recovery Ratio: The Invasive Index of LV Relaxation During Filling. Model-based Prediction with In-vivo Validation Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference. 2009 | Pubmed ID: 19963805 The Role of Left Atrial Function in Diastolic Heart Failure Circulation. Cardiovascular Imaging. Jan, 2009 | Pubmed ID: 19808558 The Age Dependence of Left Ventricular Filling Efficiency Ultrasound in Medicine & Biology. Jul, 2009 | Pubmed ID: 19427107 Stiffness and Relaxation Components of the Exponential and Logistic Time Constants May Be Used to Derive a Load-independent Index of Isovolumic Pressure Decay American Journal of Physiology. Heart and Circulatory Physiology. Dec, 2008 | Pubmed ID: 18952715 Transmitral Flow Velocity-contour Variation After Premature Ventricular Contractions: a Novel Test of the Load-independent Index of Diastolic Filling Ultrasound in Medicine & Biology. Dec, 2008 | Pubmed ID: 18692298 The Diastatic Pressure-volume Relationship is Not the Same As the End-diastolic Pressure-volume Relationship American Journal of Physiology. Heart and Circulatory Physiology. Jun, 2008 | Pubmed ID: 18424638 Physical Determinants of Left Ventricular Isovolumic Pressure Decline: Model Prediction with in Vivo Validation American Journal of Physiology. Heart and Circulatory Physiology. Apr, 2008 | Pubmed ID: 18223192 The Effects of Caloric Restriction- and Exercise-induced Weight Loss on Left Ventricular Diastolic Function American Journal of Physiology. Heart and Circulatory Physiology. Mar, 2008 | Pubmed ID: 18162561 Elucidation of Spatially Distinct Compensatory Mechanisms in Diastole: Radial Compensation for Impaired Longitudinal Filling in Left Ventricular Hypertrophy Journal of Applied Physiology (Bethesda, Md. : 1985). Feb, 2008 | Pubmed ID: 18032579 Is Left Ventricular Volume During Diastasis the Real Equilibrium Volume, and What is Its Relationship to Diastolic Suction? Journal of Applied Physiology (Bethesda, Md. : 1985). Sep, 2008 | Pubmed ID: 17901239 Pressure Phase-plane Based Determination of the Onset of Left Ventricular Relaxation Cardiovascular Engineering (Dordrecht, Netherlands). Dec, 2007 | Pubmed ID: 18026836 The Kinematic Filling Efficiency Index of the Left Ventricle: Contrasting Normal Vs. Diabetic Physiology Ultrasound in Medicine & Biology. Jun, 2007 | Pubmed ID: 17478033 Absence of Diastolic Mitral Annular Oscillations is a Marker for Relaxation-related Diastolic Dysfunction American Journal of Physiology. Heart and Circulatory Physiology. Jun, 2007 | Pubmed ID: 17308013 Stiffness- and Relaxation-based Quantitation of Radial Left Ventricular Oscillations: Elucidation of Regional Diastolic Function Mechanisms Journal of Applied Physiology (Bethesda, Md. : 1985). May, 2007 | Pubmed ID: 17255368 E-wave Deceleration Time May Not Provide an Accurate Determination of LV Chamber Stiffness if LV Relaxation/viscoelasticity is Unknown American Journal of Physiology. Heart and Circulatory Physiology. Jun, 2007 | Pubmed ID: 17220184 Contraction-relaxation Coupling Mechanism Characterization in the Thermodynamic Phase Plane: Normal Vs. Impaired Left Ventricular Ejection Fraction Journal of Applied Physiology (Bethesda, Md. : 1985). Apr, 2007 | Pubmed ID: 17185496 Derivation and Left Ventricular Pressure Phase Plane Based Validation of a Time Dependent Isometric Crossbridge Attachment Model Cardiovascular Engineering (Dordrecht, Netherlands). Dec, 2006 | Pubmed ID: 17111228 Frequency-based Analysis of the Early Rapid Filling Pressure-flow Relation Elucidates Diastolic Efficiency Mechanisms American Journal of Physiology. Heart and Circulatory Physiology. Dec, 2006 | Pubmed ID: 16891406 Diastolic Ventricular-vascular Stiffness and Relaxation Relation: Elucidation of Coupling Via Pressure Phase Plane-derived Indexes American Journal of Physiology. Heart and Circulatory Physiology. Nov, 2006 | Pubmed ID: 16731647 Relationship of Pulmonary Vein Flow to Left Ventricular Short-axis Epicardial Displacement in Diastole: Model-based Prediction with in Vivo Validation American Journal of Physiology. Heart and Circulatory Physiology. Sep, 2006 | Pubmed ID: 16603684 Load-independent Index of Diastolic Filling: Model-based Derivation with in Vivo Validation in Control and Diastolic Dysfunction Subjects Journal of Applied Physiology (Bethesda, Md. : 1985). Jul, 2006 | Pubmed ID: 16575023 Long-term Caloric Restriction Ameliorates the Decline in Diastolic Function in Humans Journal of the American College of Cardiology. Jan, 2006 | Pubmed ID: 16412867 Consequences of Increasing Heart Rate on Deceleration Time, the Velocity-time Integral, and E/A The American Journal of Cardiology. Jan, 2006 | Pubmed ID: 16377298 Isovolumic Pressure-to-early Rapid Filling Decay Rate Relation: Model-based Derivation and Validation Via Simultaneous Catheterization Echocardiography Journal of Applied Physiology (Bethesda, Md. : 1985). Feb, 2006 | Pubmed ID: 16223980 Quantitation of Mitral Annular Oscillations and Longitudinal "ringing" of the Left Ventricle: a New Window into Longitudinal Diastolic Function Journal of Applied Physiology (Bethesda, Md. : 1985). Jan, 2006 | Pubmed ID: 16150843 Diabetes and Diastolic Function: Stiffness and Relaxation from Transmitral Flow Ultrasound in Medicine & Biology. Dec, 2005 | Pubmed ID: 16344121 MRI-determined Left Ventricular "crescent Effect": a Consequence of the Slight Deviation of Contents of the Pericardial Sack from the Constant-volume State American Journal of Physiology. Heart and Circulatory Physiology. Feb, 2005 | Pubmed ID: 15486032 Prediction and Assessment of the Time-varying Effective Pulmonary Vein Area Via Cardiac MRI and Doppler Echocardiography American Journal of Physiology. Heart and Circulatory Physiology. Jan, 2005 | Pubmed ID: 15358612 The Peak Atrioventricular Pressure Gradient to Transmitral Flow Relation: Kinematic Model Prediction with in Vivo Validation Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography. Aug, 2004 | Pubmed ID: 15282487 Duration of Diastole and Its Phases As a Function of Heart Rate During Supine Bicycle Exercise American Journal of Physiology. Heart and Circulatory Physiology. Nov, 2004 | Pubmed ID: 15217800 Left Ventricular Chamber Stiffness at Rest As a Determinant of Exercise Capacity in Heart Failure Subjects with Decreased Ejection Fraction Journal of Applied Physiology (Bethesda, Md. : 1985). Nov, 2004 | Pubmed ID: 15208299 Time-varying Effective Mitral Valve Area: Prediction and Validation Using Cardiac MRI and Doppler Echocardiography in Normal Subjects American Journal of Physiology. Heart and Circulatory Physiology. Oct, 2004 | Pubmed ID: 15155259 Thermodynamic Phase Plane Analysis of Ventricular Contraction and Relaxation Biomedical Engineering Online. Mar, 2004 | Pubmed ID: 15003127 Left Atrial Conduit Volume is Generated by Deviation from the Constant-volume State of the Left Heart: a Combined MRI-echocardiographic Study American Journal of Physiology. Heart and Circulatory Physiology. Jun, 2004 | Pubmed ID: 14751859 Assessment and Consequences of the Constant-volume Attribute of the Four-chambered Heart American Journal of Physiology. Heart and Circulatory Physiology. Nov, 2003 | Pubmed ID: 12869381 The Wall-thinning to Transmitral Flow-velocity Relation: Derivation with in Vivo Validation Ultrasound in Medicine & Biology. Jun, 2002 | Pubmed ID: 12113787 The Left Ventricular Color M-mode Doppler Flow Propagation Velocity V(p): in Vivo Comparison of Alternative Methods Including Physiologic Implications Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography. Apr, 2002 | Pubmed ID: 11944012 Analysis of Left Ventricular Hemodynamics in Physiological Hyperspace Journal of Applied Physiology (Bethesda, Md. : 1985). Jan, 2002 | Pubmed ID: 11744675 Quantification de Global diastolique fonction de l'analyse basée sur la modélisation cinématique de transmitral débit via le formalisme de remplissage diastolique paramétrée Sina Mossahebi2,5, Simeng Zhu2,5, Howard Chen1,5, Leonid Shmuylovich3,5, Erina Ghosh1,5, Sándor J. Kovács4,5 1Department of Biomedical Engineering, Washington University in St. Louis, 2Department of Physics, Washington University in St. Louis, 3Division of Biology and Biomedical Sciences, Washington University in St. Louis, 4Department of Medicine, Cardiovascular Division, Washington University in St. Louis, 5Cardiovascular Biophysics Lab, Washington University in St. Louis JoVE 51471 Bioengineering
Quantification de Global diastolique fonction de l'analyse basée sur la modélisation cinématique de transmitral débit via le formalisme de remplissage diastolique paramétrée Sina Mossahebi2,5, Simeng Zhu2,5, Howard Chen1,5, Leonid Shmuylovich3,5, Erina Ghosh1,5, Sándor J. Kovács4,5 1Department of Biomedical Engineering, Washington University in St. Louis, 2Department of Physics, Washington University in St. Louis, 3Division of Biology and Biomedical Sciences, Washington University in St. Louis, 4Department of Medicine, Cardiovascular Division, Washington University in St. Louis, 5Cardiovascular Biophysics Lab, Washington University in St. Louis JoVE 51471 Bioengineering
