Silvia Deaglio Department of Medical Sciences, Human Genetics Foundation (HuGeF) University of Turin Biography Publications Institution JoVE Articles Silvia Deaglio has not added a biography. If you are Silvia Deaglio and would like to personalize this page please email our Author Liaison for assistance. Publications The Genetics of Nodal Marginal Zone Lymphoma Blood. Jun, 2016 | Pubmed ID: 27335277 MiR-214 and MiR-148b Targeting Inhibits Dissemination of Melanoma and Breast Cancer Cancer Research. Jun, 2016 | Pubmed ID: 27328731 Involvement of the P2X7-NLRP3 Axis in Leukemic Cell Proliferation and Death Scientific Reports. 2016 | Pubmed ID: 27221966 SLAMF1 Regulation of Chemotaxis and Autophagy Determines CLL Patient Response The Journal of Clinical Investigation. Jan, 2016 | Pubmed ID: 26619119 Identification of a New Subclass of ALK-negative ALCL Expressing Aberrant Levels of ERBB4 Transcripts Blood. Jan, 2016 | Pubmed ID: 26463425 Lenalidomide Interferes with Tumor-promoting Properties of Nurse-like Cells in Chronic Lymphocytic Leukemia Haematologica. Feb, 2015 | Pubmed ID: 25398834 Extracellular Nicotinamide Phosphoribosyltransferase (NAMPT) Promotes M2 Macrophage Polarization in Chronic Lymphocytic Leukemia Blood. Jan, 2015 | Pubmed ID: 25368373 Anti-CD44 MAb for the Treatment of B-cell Chronic Lymphocytic Leukemia and Other Hematological Malignancies: Evaluation of WO2013063498 Expert Opinion on Therapeutic Patents. Jul, 2014 | Pubmed ID: 24798704 HLA-G is a Component of the Chronic Lymphocytic Leukemia Escape Repertoire to Generate Immune Suppression: Impact of the HLA-G 14 Base Pair (rs66554220) Polymorphism Haematologica. May, 2014 | Pubmed ID: 24362551 Complementary and Alternative Medicine Use in Patients with Chronic Lymphocytic Leukemia: an Italian Multicentric Survey Leukemia & Lymphoma. Apr, 2014 | Pubmed ID: 23829282 Multiple Metamorphoses of CD38 from Prognostic Marker to Disease Modifier to Therapeutic Target in Chronic Lymphocytic Leukemia Current Topics in Medicinal Chemistry. 2013 | Pubmed ID: 24171772 Rs2072135, a Low-penetrance Variant for Chronic Lymphocytic Leukaemia? British Journal of Haematology. Jul, 2013 | Pubmed ID: 23668599 The Monocytic Population in Chronic Lymphocytic Leukemia Shows Altered Composition and Deregulation of Genes Involved in Phagocytosis and Inflammation Haematologica. Jul, 2013 | Pubmed ID: 23349302 The PD-1/PD-L1 Axis Contributes to T-cell Dysfunction in Chronic Lymphocytic Leukemia Haematologica. Jun, 2013 | Pubmed ID: 23300177 Biological Functions of Ecto-enzymes in Regulating Extracellular Adenosine Levels in Neoplastic and Inflammatory Disease States Journal of Molecular Medicine (Berlin, Germany). Feb, 2013 | Pubmed ID: 23292173 Targeting the Microenvironment in Chronic Lymphocytic Leukemia Offers Novel Therapeutic Options Cancer Letters. Jan, 2013 | Pubmed ID: 22910767 Chronic Lymphocytic Leukemia After Chronic Myeloid Leukemia in the Same Patient: Two Different Genomic Events and a Common Treatment? Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. Nov, 2012 | Pubmed ID: 23008321 Regulatory T-cells in Chronic Lymphocytic Leukemia and Autoimmune Diseases Mediterranean Journal of Hematology and Infectious Diseases. 2012 | Pubmed ID: 22973497 The Coding Genome of Splenic Marginal Zone Lymphoma: Activation of NOTCH2 and Other Pathways Regulating Marginal Zone Development The Journal of Experimental Medicine. Aug, 2012 | Pubmed ID: 22891273 Different Aquaporin-4 Expression in Glioblastoma Multiforme Patients with and Without Seizures Molecular Medicine (Cambridge, Mass.). 2012 | Pubmed ID: 22714714 Microenvironmental Interactions in Chronic Lymphocytic Leukemia: Hints for Pathogenesis and Identification of Targets for Rational Therapy Current Pharmaceutical Design. 2012 | Pubmed ID: 22591383 A Shorter Time to the First Treatment May Be Predicted by the Absolute Number of Regulatory T-cells in Patients with Rai Stage 0 Chronic Lymphocytic Leukemia American Journal of Hematology. Jun, 2012 | Pubmed ID: 22460620 Disruption of BIRC3 Associates with Fludarabine Chemorefractoriness in TP53 Wild-type Chronic Lymphocytic Leukemia Blood. Mar, 2012 | Pubmed ID: 22308293 Physical Contact with Endothelial Cells Through β1- and β2- Integrins Rescues Chronic Lymphocytic Leukemia Cells from Spontaneous and Drug-induced Apoptosis and Induces a Peculiar Gene Expression Profile in Leukemic Cells Haematologica. Jun, 2012 | Pubmed ID: 22207686 Mutations of NOTCH1 Are an Independent Predictor of Survival in Chronic Lymphocytic Leukemia Blood. Jan, 2012 | Pubmed ID: 22077063 Mutations of the SF3B1 Splicing Factor in Chronic Lymphocytic Leukemia: Association with Progression and Fludarabine-refractoriness Blood. Dec, 2011 | Pubmed ID: 22039264 CD73-generated Extracellular Adenosine in Chronic Lymphocytic Leukemia Creates Local Conditions Counteracting Drug-induced Cell Death Blood. Dec, 2011 | Pubmed ID: 21998208 Alteration of BIRC3 and Multiple Other NF-κB Pathway Genes in Splenic Marginal Zone Lymphoma Blood. Nov, 2011 | Pubmed ID: 21881048 CD38 and Chronic Lymphocytic Leukemia: a Decade Later Blood. Sep, 2011 | Pubmed ID: 21765022 Ectonucleotidases As Regulators of Purinergic Signaling in Thrombosis, Inflammation, and Immunity Advances in Pharmacology (San Diego, Calif.). 2011 | Pubmed ID: 21586363 Nicotinamide Blocks Proliferation and Induces Apoptosis of Chronic Lymphocytic Leukemia Cells Through Activation of the P53/miR-34a/SIRT1 Tumor Suppressor Network Cancer Research. Jul, 2011 | Pubmed ID: 21565980 Common Genetic Variation at 15q25.2 Impacts on Chronic Lymphocytic Leukaemia Risk British Journal of Haematology. Jul, 2011 | Pubmed ID: 21554262 A Highly Immunogenic Recombinant and Truncated Protein of the Secreted Aspartic Proteases Family (rSap2t) of Candida Albicans As a Mucosal Anticandidal Vaccine FEMS Immunology and Medical Microbiology. Jul, 2011 | Pubmed ID: 21535228 NAD+-metabolizing Ecto-enzymes Shape Tumor-host Interactions: the Chronic Lymphocytic Leukemia Model FEBS Letters. Jun, 2011 | Pubmed ID: 21514298 Oct-4+/Tenascin C+ Neuroblastoma Cells Serve As Progenitors of Tumor-derived Endothelial Cells Cell Research. Oct, 2011 | Pubmed ID: 21403679 A Variant of the LRP4 Gene Affects the Risk of Chronic Lymphocytic Leukaemia Transformation to Richter Syndrome British Journal of Haematology. Feb, 2011 | Pubmed ID: 21121903 Variable Impact of CD39 in Experimental Murine Colitis Digestive Diseases and Sciences. May, 2011 | Pubmed ID: 20936356 Regulatory T-cell Number is Increased in Chronic Lymphocytic Leukemia Patients and Correlates with Progressive Disease Leukemia Research. Mar, 2011 | Pubmed ID: 20880586 Multicentre Validation of a Prognostic Index for Overall Survival in Chronic Lymphocytic Leukaemia Hematological Oncology. Jun, 2011 | Pubmed ID: 20669154 Chronic Lymphocytic Leukemia-associated Immune Thrombocytopenia Treated with Rituximab: a Retrospective Study of 21 Patients European Journal of Haematology. Dec, 2010 | Pubmed ID: 20846302 CD38 As a Molecular Compass Guiding Topographical Decisions of Chronic Lymphocytic Leukemia Cells Seminars in Cancer Biology. Dec, 2010 | Pubmed ID: 20817095 The Hidden Life of NAD+-consuming Ectoenzymes in the Endocrine System Journal of Molecular Endocrinology. Oct, 2010 | Pubmed ID: 20660167 Transferrin Receptor 2 is Frequently and Highly Expressed in Glioblastomas Translational Oncology. Apr, 2010 | Pubmed ID: 20360937 Monocytes/macrophages but Not T Lymphocytes Are the Major Targets of the CCL3/CCL4 Chemokines Produced by CD38(+)CD49d(+) Chronic Lymphocytic Leukaemia Cells British Journal of Haematology. Jul, 2010 | Pubmed ID: 20346010 Genetic Modification of Primary Chronic Lymphocytic Leukemia Cells with a Lentivirus Expressing CD38 Haematologica. Mar, 2010 | Pubmed ID: 20207849 CD38/CD31 Interactions Activate Genetic Pathways Leading to Proliferation and Migration in Chronic Lymphocytic Leukemia Cells Molecular Medicine (Cambridge, Mass.). Mar, 2010 | Pubmed ID: 19956559 TfR2 Expression in Human Colon Carcinomas Blood Cells, Molecules & Diseases. Nov-Dec, 2009 | Pubmed ID: 19729324 Intrinsic and Extrinsic Factors Influencing the Clinical Course of B-cell Chronic Lymphocytic Leukemia: Prognostic Markers with Pathogenetic Relevance Journal of Translational Medicine. 2009 | Pubmed ID: 19715592 Stereotyped B-cell Receptor is an Independent Risk Factor of Chronic Lymphocytic Leukemia Transformation to Richter Syndrome Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jul, 2009 | Pubmed ID: 19509140 Chronic Lymphocytic Leukemia Microenvironment: Shifting the Balance from Apoptosis to Proliferation Haematologica. Jun, 2009 | Pubmed ID: 19483151 CD38/CD31, the CCL3 and CCL4 Chemokines, and CD49d/vascular Cell Adhesion Molecule-1 Are Interchained by Sequential Events Sustaining Chronic Lymphocytic Leukemia Cell Survival Cancer Research. May, 2009 | Pubmed ID: 19383907 CD38 and CD157 Ectoenzymes Mark Cell Subsets in the Human Corneal Limbus Molecular Medicine (Cambridge, Mass.). Mar-Apr, 2009 | Pubmed ID: 19052657 Regulation of Transferrin Receptor 2 in Human Cancer Cell Lines Blood Cells, Molecules & Diseases. Jan-Feb, 2009 | Pubmed ID: 19019709 Evolution and Function of the ADP Ribosyl Cyclase/CD38 Gene Family in Physiology and Pathology Physiological Reviews. Jul, 2008 | Pubmed ID: 18626062 CD38 Gene Polymorphism and Chronic Lymphocytic Leukemia: a Role in Transformation to Richter Syndrome? Blood. Jun, 2008 | Pubmed ID: 18424664 CD38 at the Junction Between Prognostic Marker and Therapeutic Target Trends in Molecular Medicine. May, 2008 | Pubmed ID: 18403265 CD39 and Control of Cellular Immune Responses Purinergic Signalling. Mar, 2007 | Pubmed ID: 18404431 Regulation of CD38 in Proliferating Chronic Lymphocytic Leukemia Cells Stimulated with CD154 and Interleukin-4 Haematologica. Oct, 2007 | Pubmed ID: 18024373 CD38 and ZAP-70 Are Functionally Linked and Mark CLL Cells with High Migratory Potential Blood. Dec, 2007 | Pubmed ID: 17699742 Prognostic Significance of Combined Analysis of ZAP-70 and CD38 in Chronic Lymphocytic Leukemia American Journal of Hematology. Sep, 2007 | Pubmed ID: 17534928 Adenosine Generation Catalyzed by CD39 and CD73 Expressed on Regulatory T Cells Mediates Immune Suppression The Journal of Experimental Medicine. Jun, 2007 | Pubmed ID: 17502665 Transferrin Receptor 2 is Frequently Expressed in Human Cancer Cell Lines Blood Cells, Molecules & Diseases. Jul-Aug, 2007 | Pubmed ID: 17428703 CD38/CD19: a Lipid Raft-dependent Signaling Complex in Human B Cells Blood. Jun, 2007 | Pubmed ID: 17327405 The CD38/CD157 Mammalian Gene Family: An Evolutionary Paradigm for Other Leukocyte Surface Enzymes Purinergic Signalling. Jun, 2006 | Pubmed ID: 18404481 The CD38 Ectoenzyme Family: Advances in Basic Science and Clinical Practice Molecular Medicine (Cambridge, Mass.). Nov-Dec, 2006 | Pubmed ID: 17380202 CD38 and CD157 As Receptors of the Immune System: a Bridge Between Innate and Adaptive Immunity Molecular Medicine (Cambridge, Mass.). Nov-Dec, 2006 | Pubmed ID: 17380201 TfR2 Localizes in Lipid Raft Domains and is Released in Exosomes to Activate Signal Transduction Along the MAPK Pathway Journal of Cell Science. Nov, 2006 | Pubmed ID: 17046995 In-tandem Insight from Basic Science Combined with Clinical Research: CD38 As Both Marker and Key Component of the Pathogenetic Network Underlying Chronic Lymphocytic Leukemia Blood. Aug, 2006 | Pubmed ID: 16621959 CD38 Orchestrates Migration, Survival, and Th1 Immune Response of Human Mature Dendritic Cells Blood. Mar, 2006 | Pubmed ID: 16293598 Immunodetection of Anti-MAG IgM Antibody by Cross-reactivity to LA-N-1 Neuroblastoma Cells Journal of Neuroimmunology. Apr, 2005 | Pubmed ID: 15748946 CD38 and CD100 Lead a Network of Surface Receptors Relaying Positive Signals for B-CLL Growth and Survival Blood. Apr, 2005 | Pubmed ID: 15613544 Transferrin Receptor 2 Protein is Not Expressed in Normal Erythroid Cells The Biochemical Journal. Aug, 2004 | Pubmed ID: 15084147 Death of T Cell Precursors in the Human Thymus: a Role for CD38 International Immunology. Sep, 2003 | Pubmed ID: 12917263 CD38 is a Signaling Molecule in B-cell Chronic Lymphocytic Leukemia Cells Blood. Sep, 2003 | Pubmed ID: 12763926 Role of CD31/platelet Endothelial Cell Adhesion Molecule-1 Expression in in Vitro and in Vivo Growth and Differentiation of Human Breast Cancer Cells The American Journal of Pathology. Apr, 2003 | Pubmed ID: 12651608 Simultaneous Expression of CD38 and Its Ligand CD31 by Chronic Lymphocytic Leukemia B-cells: Anecdotal Observation or Pathogenetic Hypothesis for the Clinical Outcome? Haematologica. Mar, 2003 | Pubmed ID: 12651280 Human CD38 Interferes with HIV-1 Fusion Through a Sequence Homologous to the V3 Loop of the Viral Envelope Glycoprotein Gp120 FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Mar, 2003 | Pubmed ID: 12551845 Expression of Ribosomal and Translation-associated Genes is Correlated with a Favorable Clinical Course in Chronic Lymphocytic Leukemia Blood. Apr, 2003 | Pubmed ID: 12456497 CD38 Ligation Plays a Direct Role in the Induction of IL-1beta, IL-6, and IL-10 Secretion in Resting Human Monocytes Cellular Immunology. Nov, 2002 | Pubmed ID: 12718937 Structural, Functional, and Tissue Distribution Analysis of Human Transferrin Receptor-2 by Murine Monoclonal Antibodies and a Polyclonal Antiserum Blood. Nov, 2002 | Pubmed ID: 12393650 Arsenic Trioxide and Breast Cancer: Analysis of the Apoptotic, Differentiative and Immunomodulatory Effects Breast Cancer Research and Treatment. May, 2002 | Pubmed ID: 12083632 Oxytocin is a Growth Factor for Kaposi's Sarcoma Cells: Evidence of Endocrine-immunological Cross-talk Cancer Research. Apr, 2002 | Pubmed ID: 11956104 Human CD38 and CD16 Are Functionally Dependent and Physically Associated in Natural Killer Cells Blood. Apr, 2002 | Pubmed ID: 11895784 Peripheral Blood CD38 Expression Predicts Time to Progression in B-cell Chronic Lymphocytic Leukemia After First-line Therapy with High-dose Chlorambucil Haematologica. Feb, 2002 | Pubmed ID: 11836173 एचपीएलसी आधारित परख मानव पुरानी लिम्फोसाईटिक ल्यूकेमिया कोशिकाओं में कोशिकी Nucleotide / nucleoside चयापचय नजर रखने के लिए Sara Serra1, Silvia Deaglio1 1Department of Medical Sciences, Human Genetics Foundation (HuGeF), University of Turin Chemistry
एचपीएलसी आधारित परख मानव पुरानी लिम्फोसाईटिक ल्यूकेमिया कोशिकाओं में कोशिकी Nucleotide / nucleoside चयापचय नजर रखने के लिए Sara Serra1, Silvia Deaglio1 1Department of Medical Sciences, Human Genetics Foundation (HuGeF), University of Turin Chemistry