Simon M. Hughes

Publications

• Cellular and Molecular Pathways Controlling Muscle Size in Response to Exercise
  The FEBS Journal. 03, 2022  |   Pubmed ID: 33755332
• Isolation of Myofibres and Culture of Muscle Stem Cells from Adult Zebrafish
  Bio-protocol. Sep, 2021  |   Pubmed ID: 34604454
• MRNP Granule Proteins Fmrp and Dcp1a Differentially Regulate MRNP Complexes to Contribute to Control of Muscle Stem Cell Quiescence and Activation
  Skeletal Muscle. 07, 2021  |   Pubmed ID: 34238354
• Knockout of Zebrafish Desmin Genes Does Not Cause Skeletal Muscle Degeneration but Alters Calcium Flux
  Scientific Reports. 04, 2021  |   Pubmed ID: 33820917
• Mef2c Factors Are Required for Early but Not Late Addition of Cardiomyocytes to the Ventricle
  Developmental Biology. 02, 2021  |   Pubmed ID: 33245870
• Circadian Regulation of Muscle Growth Independent of Locomotor Activity
  Proceedings of the National Academy of Sciences of the United States of America. 12, 2020  |   Pubmed ID: 33229575
• Myogenin is an Essential Regulator of Adult Myofibre Growth and Muscle Stem Cell Homeostasis
  ELife. 10, 2020  |   Pubmed ID: 33001028
• Fgf-driven Tbx Protein Activities Directly Induce and to Initiate Zebrafish Myogenesis
  Development (Cambridge, England). 04, 2020  |   Pubmed ID: 32345657
• Maternal Larp6 Controls Oocyte Development, Chorion Formation and Elevation
  Development (Cambridge, England). 02, 2020  |   Pubmed ID: 32054660
• EGF Receptor (EGFR) Inhibition Promotes a Slow-twitch Oxidative, over a Fast-twitch, Muscle Phenotype
  Scientific Reports. 06, 2019  |   Pubmed ID: 31239465
• Scleraxis Genes Are Required for Normal Musculoskeletal Development and for Rib Growth and Mineralization in Zebrafish
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. 08, 2019  |   Pubmed ID: 31100023
• Myogenin Promotes Myocyte Fusion to Balance Fibre Number and Size
  Nature Communications. 10, 2018  |   Pubmed ID: 30315160
• Mef2 and the Skeletal Muscle Differentiation Program
  Seminars in Cell & Developmental Biology. 12, 2017  |   Pubmed ID: 29154822
• Myotome Adaptability Confers Developmental Robustness to Somitic Myogenesis in Response to Fibre Number Alteration
  Developmental Biology. 11, 2017  |   Pubmed ID: 28887016
• CRISPR/Cas9 Editing Reveals Novel Mechanisms of Clustered MicroRNA Regulation and Function
  Scientific Reports. 08, 2017  |   Pubmed ID: 28819307
• The Cannabinoid Receptor Interacting Proteins 1 of Zebrafish Are Not Required for Morphological Development, Viability or Fertility
  Scientific Reports. 07, 2017  |   Pubmed ID: 28687732
• Cellular Dynamics of Regeneration Reveals Role of Two Distinct Pax7 Stem Cell Populations in Larval Zebrafish Muscle Repair
  Disease Models & Mechanisms. 06, 2016  |   Pubmed ID: 27149989
• In Vivo Dynamics of Skeletal Muscle Dystrophin in Zebrafish Embryos Revealed by Improved FRAP Analysis
  ELife. Oct, 2015  |   Pubmed ID: 26459831
• Anaesthetic Tricaine Acts Preferentially on Neural Voltage-gated Sodium Channels and Fails to Block Directly Evoked Muscle Contraction
  PloS One. 2014  |   Pubmed ID: 25090007
• EIF4EBP3L Acts As a Gatekeeper of TORC1 in Activity-dependent Muscle Growth by Specifically Regulating Mef2ca Translational Initiation
  PLoS Biology. Oct, 2013  |   Pubmed ID: 24143132
• Notch Signalling is Required for the Formation of Structurally Stable Muscle Fibres in Zebrafish
  PloS One. 2013  |   Pubmed ID: 23840804
• Oesophageal and Sternohyal Muscle Fibres Are Novel Pax3-dependent Migratory Somite Derivatives Essential for Ingestion
  Development (Cambridge, England). Jul, 2013  |   Pubmed ID: 23760954
• Zebrafish Mef2ca and Mef2cb Are Essential for Both First and Second Heart Field Cardiomyocyte Differentiation
  Developmental Biology. Sep, 2012  |   Pubmed ID: 22750409
• Defective Cranial Skeletal Development, Larval Lethality and Haploinsufficiency in Myod Mutant Zebrafish
  Developmental Biology. Oct, 2011  |   Pubmed ID: 21798255
• Cdkn1c Drives Muscle Differentiation Through a Positive Feedback Loop with Myod
  Developmental Biology. Feb, 2011  |   Pubmed ID: 21147088
• Differential Requirements for Myogenic Regulatory Factors Distinguish Medial and Lateral Somitic, Cranial and Fin Muscle Fibre Populations
  Development (Cambridge, England). Feb, 2009  |   Pubmed ID: 19141670
• Other Model Organisms for Sarcomeric Muscle Diseases
  Advances in Experimental Medicine and Biology. 2008  |   Pubmed ID: 19181102
• Wnt Signaling Promotes AChR Aggregation at the Neuromuscular Synapse in Collaboration with Agrin
  Proceedings of the National Academy of Sciences of the United States of America. Dec, 2008  |   Pubmed ID: 19020093
• Nerve-dependent Changes in Skeletal Muscle Myosin Heavy Chain After Experimental Denervation and Cross-reinnervation and in a Demyelinating Mouse Model of Charcot-Marie-Tooth Disease Type 1A
  Muscle & Nerve. Dec, 2008  |   Pubmed ID: 19016545
• Sequential Actions of Pax3 and Pax7 Drive Xanthophore Development in Zebrafish Neural Crest
  Developmental Biology. May, 2008  |   Pubmed ID: 18417109
• Development of Mandibular, Hyoid and Hypobranchial Muscles in the Zebrafish: Homologies and Evolution of These Muscles Within Bony Fishes and Tetrapods
  BMC Developmental Biology. Feb, 2008  |   Pubmed ID: 18307809
• MyoD- and Nerve-dependent Maintenance of MyoD Expression in Mature Muscle Fibres Acts Through the DRR/PRR Element
  BMC Developmental Biology. Jan, 2008  |   Pubmed ID: 18215268
• Dystrobrevin and Dystrophin Family Gene Expression in Zebrafish
  Gene Expression Patterns : GEP. Jan, 2008  |   Pubmed ID: 18042440
• Vestigial-like-2b (VITO-1b) and Tead-3a (Tef-5a) Expression in Zebrafish Skeletal Muscle, Brain and Notochord
  Gene Expression Patterns : GEP. Oct, 2007  |   Pubmed ID: 17916448
• Mrf4 (myf6) is Dynamically Expressed in Differentiated Zebrafish Skeletal Muscle
  Gene Expression Patterns : GEP. Aug, 2007  |   Pubmed ID: 17638597
• Mef2s Are Required for Thick Filament Formation in Nascent Muscle Fibres
  Development (Cambridge, England). Jul, 2007  |   Pubmed ID: 17537787
• The Dystrotelin, Dystrophin and Dystrobrevin Superfamily: New Paralogues and Old Isoforms
  BMC Genomics. Jan, 2007  |   Pubmed ID: 17233888
• Signals and Myogenic Regulatory Factors Restrict Pax3 and Pax7 Expression to Dermomyotome-like Tissue in Zebrafish
  Developmental Biology. Feb, 2007  |   Pubmed ID: 17094960
• Comparison of Neurolin (ALCAM) and Neurolin-like Cell Adhesion Molecule (NLCAM) Expression in Zebrafish
  Gene Expression Patterns : GEP. Oct, 2006  |   Pubmed ID: 16750657
• Evidence That Satellite Cell Decrement Contributes to Preferential Decline in Nuclear Number from Large Fibres During Murine Age-related Muscle Atrophy
  Journal of Cell Science. Oct, 2005  |   Pubmed ID: 16219688
• Fgf8 Drives Myogenic Progression of a Novel Lateral Fast Muscle Fibre Population in Zebrafish
  Development (Cambridge, England). Oct, 2005  |   Pubmed ID: 16120642
• The Kinase Domain of Titin Controls Muscle Gene Expression and Protein Turnover
  Science (New York, N.Y.). Jun, 2005  |   Pubmed ID: 15802564
• Hedgehog Can Drive Terminal Differentiation of Amniote Slow Skeletal Muscle
  BMC Developmental Biology. Jul, 2004  |   Pubmed ID: 15238161
• Hedgehog Regulation of Superficial Slow Muscle Fibres in Xenopus and the Evolution of Tetrapod Trunk Myogenesis
  Development (Cambridge, England). Jul, 2004  |   Pubmed ID: 15201218
• Muscle Differentiation: a Gene for Slow Muscle?
  Current Biology : CB. Feb, 2004  |   Pubmed ID: 15027468
• Intermediate Filament-co-localized Molecules with Myosin Heavy Chain Epitopes Define Distinct Cellular Domains in Hair Follicles and Epidermis
  BMC Cell Biology. Aug, 2003  |   Pubmed ID: 12899730
• Acridine Mutagenesis of Zebrafish (Danio Rerio)
  Mutation Research. Apr, 2003  |   Pubmed ID: 12650900
• Aging-related Satellite Cell Differentiation Defect Occurs Prematurely After Ski-induced Muscle Hypertrophy
  American Journal of Physiology. Cell Physiology. Oct, 2002  |   Pubmed ID: 12225986
• Muscular Expressions: Profiling Genes in Complex Tissues
  Genome Biology. 2001  |   Pubmed ID: 11790260
• Myogenin Induces a Shift of Enzyme Activity from Glycolytic to Oxidative Metabolism in Muscles of Transgenic Mice
  The Journal of Cell Biology. May, 1999  |   Pubmed ID: 10225962
• The Role of Hedgehog Proteins in Vertebrate Slow and Fast Skeletal Muscle Patterning
  Acta Physiologica Scandinavica. Jul, 1998  |   Pubmed ID: 9715744
• Notochord Induction of Zebrafish Slow Muscle Mediated by Sonic Hedgehog
  Genes & Development. Sep, 1997  |   Pubmed ID: 9303533
• MyoD Protein is Differentially Accumulated in Fast and Slow Skeletal Muscle Fibres and Required for Normal Fibre Type Balance in Rodents
  Mechanisms of Development. Jan, 1997  |   Pubmed ID: 9076685