In JoVE (1)
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Articles by Steven R. A. Burke in JoVE
Levator Auris Longus Preparation for Examination of Mammalian Neuromuscular Transmission Under Voltage Clamp Conditions Steven R. A. Burke1, Eric J. Reed1, Shannon H. Romer1, Andrew A. Voss1 1Department of Biological Sciences, Wright State University The protocol described in this paper uses the mouse levator auris longus (LAL) muscle to record spontaneous and nerve-evoked postsynaptic potentials (current-clamp) and currents (voltage-clamp) at the neuromuscular junction. Use of this technique can provide key insights into mechanisms of synaptic transmission under normal and disease conditions.