Susan R. Weiss Department of Microbiology University of Pennsylvania Biography Publications Institution JoVE Articles Susan R. Weiss has not added a biography. If you are Susan R. Weiss and would like to personalize this page please email our Author Liaison for assistance. Publications Comparison of SARS-CoV-2 Variants in Primary Human Nasal Cultures Indicates Delta As Most Cytopathic and Omicron As Fastest Replicating BioRxiv : the Preprint Server for Biology. Aug, 2023 | Pubmed ID: 37662273 Detection of Blood-brain Barrier Disruption in Brains of Patients with COVID-19, but No Evidence of Brain Penetration by SARS-CoV-2 Acta Neuropathologica. Aug, 2023 | Pubmed ID: 37624381 Infection of Primary Nasal Epithelial Cells Differentiates Among Lethal and Seasonal Human Coronaviruses Proceedings of the National Academy of Sciences of the United States of America. Apr, 2023 | Pubmed ID: 37023127 Author Correction: SARS-CoV-2 Disrupts Host Epigenetic Regulation Via Histone Mimicry Nature. Feb, 2023 | Pubmed ID: 36747034 Publisher Correction: SARS-CoV-2 Disrupts Host Epigenetic Regulation Via Histone Mimicry Nature. Jan, 2023 | Pubmed ID: 36624294 Inborn Errors of OAS-RNase L in SARS-CoV-2-related Multisystem Inflammatory Syndrome in Children Science (New York, N.Y.). Feb, 2023 | Pubmed ID: 36538032 Infection of Primary Nasal Epithelial Cells Differentiates Among Lethal and Seasonal Human Coronaviruses BioRxiv : the Preprint Server for Biology. Oct, 2022 | Pubmed ID: 36299422 SARS-CoV-2 Disrupts Host Epigenetic Regulation Via Histone Mimicry Nature. Oct, 2022 | Pubmed ID: 36198800 Targeted Mutations in the Fusion Peptide Region of La Crosse Virus Attenuate Neuroinvasion and Confer Protection Against Encephalitis Viruses. Jul, 2022 | Pubmed ID: 35891445 SARS-CoV-2 Diverges from Other Betacoronaviruses in Only Partially Activating the IRE1α/XBP1 ER Stress Pathway in Human Lung-derived Cells BioRxiv : the Preprint Server for Biology. Jun, 2022 | Pubmed ID: 35821981 MERS-CoV Endoribonuclease and Accessory Proteins Jointly Evade Host Innate Immunity During Infection of Lung and Nasal Epithelial Cells Proceedings of the National Academy of Sciences of the United States of America. May, 2022 | Pubmed ID: 35594398 SARS-CoV-2 Delta Variant (AY.3) in the Feces of a Domestic Cat Viruses. Feb, 2022 | Pubmed ID: 35216014 Detection and Interspecies Comparison of SARS-CoV-2 Delta Variant (AY.3) in Feces from a Domestic Cat and Human Samples BioRxiv : the Preprint Server for Biology. Feb, 2022 | Pubmed ID: 35132417 Adenovirus Prevents DsRNA Formation by Promoting Efficient Splicing of Viral RNA Nucleic Acids Research. Feb, 2022 | Pubmed ID: 34671803 Subcellular Detection of SARS-CoV-2 RNA in Human Tissue Reveals Distinct Localization in Alveolar Type 2 Pneumocytes and Alveolar Macrophages MBio. Feb, 2021 | Pubmed ID: 35130722 Single- and Two-Stage, Closed-Tube, Point-of-Care, Molecular Detection of SARS-CoV-2 Analytical Chemistry. Sep, 2021 | Pubmed ID: 34541844 The Origins of SARS-CoV-2: A Critical Review Cell. Sep, 2021 | Pubmed ID: 34480864 Multiplexed Detection of SARS-CoV-2 Genomic and Subgenomic RNA Using Hybridization BioRxiv : the Preprint Server for Biology. Aug, 2021 | Pubmed ID: 34401878 Femtomolar SARS-CoV-2 Antigen Detection Using the Microbubbling Digital Assay with Smartphone Readout Enables Antigen Burden Quantitation and Tracking Clinical Chemistry. Dec, 2021 | Pubmed ID: 34383886 Author Correction: Molecular Determinants and Mechanism for Antibody Cocktail Preventing SARS-CoV-2 Escape Nature Communications. Jul, 2021 | Pubmed ID: 34210985 Detection of SARS-CoV-2 RNA Using RT-LAMP and Molecular Beacons Genome Biology. Jun, 2021 | Pubmed ID: 34082799 Zika Virus Employs the Host Antiviral RNase L Protein to Support Replication Factory Assembly Proceedings of the National Academy of Sciences of the United States of America. Jun, 2021 | Pubmed ID: 34031250 Discrimination of SARS-CoV-2 Infected Patient Samples by Detection Dogs: A Proof of Concept Study PloS One. 2021 | Pubmed ID: 33852639 SARS-CoV-2 Induces Double-stranded RNA-mediated Innate Immune Responses in Respiratory Epithelial-derived Cells and Cardiomyocytes Proceedings of the National Academy of Sciences of the United States of America. 04, 2021 | Pubmed ID: 33811184 Femtomolar SARS-CoV-2 Antigen Detection Using the Microbubbling Digital Assay with Smartphone Readout Enables Antigen Burden Quantitation and Dynamics Tracking MedRxiv : the Preprint Server for Health Sciences. Mar, 2021 | Pubmed ID: 33791710 Activation of STING Signaling Pathway Effectively Blocks Human Coronavirus Infection Journal of Virology. May, 2021 | Pubmed ID: 33789998 Copan ENAT Transport System To Address Challenges in COVID-19 Diagnostics in Regions with Limited Testing Access Journal of Clinical Microbiology. Apr, 2021 | Pubmed ID: 33579730 Molecular Determinants and Mechanism for Antibody Cocktail Preventing SARS-CoV-2 Escape Nature Communications. Jan, 2021 | Pubmed ID: 33473140 SARS-CoV-2 Genomic Variation in Space and Time in Hospitalized Patients in Philadelphia MBio. Jan, 2021 | Pubmed ID: 33468702 Physiologic RNA Targets and Refined Sequence Specificity of Coronavirus EndoU RNA (New York, N.Y.). Dec, 2020 | Pubmed ID: 32989044 A Phenolic Small Molecule Inhibitor of RNase L Prevents Cell Death from ADAR1 Deficiency Proceedings of the National Academy of Sciences of the United States of America. Oct, 2020 | Pubmed ID: 32958664 Broad Anti-coronavirus Activity of Food and Drug Administration-Approved Drugs Against SARS-CoV-2 and SARS-CoV Journal of Virology. Oct, 2020 | Pubmed ID: 32817221 Forty Years with Coronaviruses The Journal of Experimental Medicine. May, 2020 | Pubmed ID: 32232339 No Credible Evidence Supporting Claims of the Laboratory Engineering of SARS-CoV-2 Emerging Microbes & Infections. 2020 | Pubmed ID: 32102621 Activation of RNase L in Egyptian Rousette Bat-Derived RoNi/7 Cells Is Dependent Primarily on OAS3 and Independent of MAVS Signaling MBio. Nov, 2019 | Pubmed ID: 31719180 Zika Virus Production Is Resistant to RNase L Antiviral Activity Journal of Virology. Aug, 2019 | Pubmed ID: 31142667 Antagonism of DsRNA-Induced Innate Immune Pathways by NS4a and NS4b Accessory Proteins During MERS Coronavirus Infection MBio. Mar, 2019 | Pubmed ID: 30914508 OAS-RNase L Innate Immune Pathway Mediates the Cytotoxicity of a DNA-demethylating Drug Proceedings of the National Academy of Sciences of the United States of America. Mar, 2019 | Pubmed ID: 30814222 Real-time 2-5A Kinetics Suggest That Interferons β and λ Evade Global Arrest of Translation by RNase L Proceedings of the National Academy of Sciences of the United States of America. Feb, 2019 | Pubmed ID: 30655338 Third Tofo Advanced Study Week on Emerging and Re-emerging Viruses, 2018 Antiviral Research. Feb, 2019 | Pubmed ID: 30597184 A Novel Mechanism of RNase L Inhibition: Theiler's Virus L* Protein Prevents 2-5A from Binding to RNase L PLoS Pathogens. Apr, 2018 | Pubmed ID: 29652922 Murine Hepatitis Virus Nsp14 Exoribonuclease Activity Is Required for Resistance to Innate Immunity Journal of Virology. Jan, 2018 | Pubmed ID: 29046453 Origins and Pathogenesis of Middle East Respiratory Syndrome-associated Coronavirus: Recent Advances F1000Research. 2017 | Pubmed ID: 29026532 Replication Defective Viral Genomes Exploit a Cellular Pro-survival Mechanism to Establish Paramyxovirus Persistence Nature Communications. Oct, 2017 | Pubmed ID: 28986577 Role of the Inflammasome-related Cytokines Il-1 and Il-18 During Infection with Murine Coronavirus Journal of Neurovirology. Dec, 2017 | Pubmed ID: 28895072 Ribonuclease L Mediates the Cell-lethal Phenotype of Double-stranded RNA Editing Enzyme ADAR1 Deficiency in a Human Cell Line ELife. Mar, 2017 | Pubmed ID: 28362255 Early Endonuclease-mediated Evasion of RNA Sensing Ensures Efficient Coronavirus Replication PLoS Pathogens. Feb, 2017 | Pubmed ID: 28158275 Neurovirulent Murine Coronavirus JHM.SD Uses Cellular Zinc Metalloproteases for Virus Entry and Cell-Cell Fusion Journal of Virology. Apr, 2017 | Pubmed ID: 28148786 Lineage A Betacoronavirus NS2 Proteins and the Homologous Torovirus Berne Pp1a Carboxy-Terminal Domain Are Phosphodiesterases That Antagonize Activation of RNase L Journal of Virology. Mar, 2017 | Pubmed ID: 28003490 Antagonism of RNase L Is Required for Murine Coronavirus Replication in Kupffer Cells and Liver Sinusoidal Endothelial Cells but Not in Hepatocytes Journal of Virology. Nov, 2016 | Pubmed ID: 27558415 Middle East Respiratory Syndrome Coronavirus NS4b Protein Inhibits Host RNase L Activation MBio. Mar, 2016 | Pubmed ID: 27025250 Activation of RNase L is Dependent on OAS3 Expression During Infection with Diverse Human Viruses Proceedings of the National Academy of Sciences of the United States of America. Feb, 2016 | Pubmed ID: 26858407 Primary Role for Toll-Like Receptor-Driven Tumor Necrosis Factor Rather Than Cytosolic Immune Detection in Restricting Coxiella Burnetii Phase II Replication Within Mouse Macrophages Infection and Immunity. Apr, 2016 | Pubmed ID: 26787725 Crystal Structure of the Mouse Hepatitis Virus Ns2 Phosphodiesterase Domain That Antagonizes RNase L Activation The Journal of General Virology. Apr, 2016 | Pubmed ID: 26757803 Activation of RNase L by Murine Coronavirus in Myeloid Cells Is Dependent on Basal Oas Gene Expression and Independent of Virus-Induced Interferon Journal of Virology. Jan, 2016 | Pubmed ID: 26739051 RNase L is a Negative Regulator of Cell Migration Oncotarget. Dec, 2015 | Pubmed ID: 26517238 MDA5 Is Critical to Host Defense During Infection with Murine Coronavirus Journal of Virology. Dec, 2015 | Pubmed ID: 26423942 Structural Basis for 2'-5'-oligoadenylate Binding and Enzyme Activity of a Viral RNase L Antagonist Journal of Virology. Jul, 2015 | Pubmed ID: 25878106 The Nsp1, Nsp13, and M Proteins Contribute to the Hepatotropism of Murine Coronavirus JHM.WU Journal of Virology. Apr, 2015 | Pubmed ID: 25589656 Coronavirus-induced Demyelination of Neural Pathways Triggers Neurogenic Bladder Overactivity in a Mouse Model of Multiple Sclerosis American Journal of Physiology. Renal Physiology. Sep, 2014 | Pubmed ID: 25007876 Murine AKAP7 Has a 2',5'-phosphodiesterase Domain That Can Complement an Inactive Murine Coronavirus Ns2 Gene MBio. Jul, 2014 | Pubmed ID: 24987090 Viral Phosphodiesterases That Antagonize Double-stranded RNA Signaling to RNase L by Degrading 2-5A Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research. Jun, 2014 | Pubmed ID: 24905202 Evaluation of SSYA10-001 As a Replication Inhibitor of Severe Acute Respiratory Syndrome, Mouse Hepatitis, and Middle East Respiratory Syndrome Coronaviruses Antimicrobial Agents and Chemotherapy. Aug, 2014 | Pubmed ID: 24841268 Cell-type-specific Effects of RNase L on Viral Induction of Beta Interferon MBio. Feb, 2014 | Pubmed ID: 24570368 Analysis of the Host Transcriptome from Demyelinating Spinal Cord of Murine Coronavirus-infected Mice PloS One. 2013 | Pubmed ID: 24058676 Homologous 2',5'-phosphodiesterases from Disparate RNA Viruses Antagonize Antiviral Innate Immunity Proceedings of the National Academy of Sciences of the United States of America. Aug, 2013 | Pubmed ID: 23878220 Cell-type-specific Activation of the Oligoadenylate Synthetase-RNase L Pathway by a Murine Coronavirus Journal of Virology. Aug, 2013 | Pubmed ID: 23698313 Novel Inhibitors of Severe Acute Respiratory Syndrome Coronavirus Entry That Act by Three Distinct Mechanisms Journal of Virology. Jul, 2013 | Pubmed ID: 23678171 Antagonism of the Interferon-induced OAS-RNase L Pathway by Murine Coronavirus Ns2 Protein is Required for Virus Replication and Liver Pathology Cell Host & Microbe. Jun, 2012 | Pubmed ID: 22704621 A Novel Full-length Isoform of Murine Pregnancy-specific Glycoprotein 16 (psg16) is Expressed in the Brain but Does Not Mediate Murine Coronavirus (MHV) Entry Journal of Neurovirology. Apr, 2012 | Pubmed ID: 22302612 Coronavirus Pathogenesis Advances in Virus Research. 2011 | Pubmed ID: 22094080 The Role of Interferon Antagonist, Non-structural Proteins in the Pathogenesis and Emergence of Arboviruses Viruses. Jun, 2011 | Pubmed ID: 21994750 Cell-type-specific Type I Interferon Antagonism Influences Organ Tropism of Murine Coronavirus Journal of Virology. Oct, 2011 | Pubmed ID: 21752905 Characteristics of Opioid Prescriptions in 2009 JAMA. Apr, 2011 | Pubmed ID: 21467282 Pathogenesis of Neurotropic Murine Coronavirus is Multifactorial Trends in Pharmacological Sciences. Jan, 2011 | Pubmed ID: 21144598 Murine Coronavirus Neuropathogenesis: Determinants of Virulence Journal of Neurovirology. Nov, 2010 | Pubmed ID: 21073281 Murine Coronavirus Receptors Are Differentially Expressed in the Central Nervous System and Play Virus Strain-dependent Roles in Neuronal Spread Journal of Virology. Nov, 2010 | Pubmed ID: 20739537 Genetic Determinants of Mouse Hepatitis Virus Strain 1 Pneumovirulence Journal of Virology. Sep, 2010 | Pubmed ID: 20631137 Pathogenesis of Murine Coronavirus in the Central Nervous System Journal of Neuroimmune Pharmacology : the Official Journal of the Society on NeuroImmune Pharmacology. Sep, 2010 | Pubmed ID: 20369302 Murine Coronavirus Delays Expression of a Subset of Interferon-stimulated Genes Journal of Virology. Jun, 2010 | Pubmed ID: 20357099 The Murine Coronavirus Nucleocapsid Gene is a Determinant of Virulence Journal of Virology. Feb, 2010 | Pubmed ID: 20007284 Murine Coronavirus Cell Type Dependent Interaction with the Type I Interferon Response Viruses. Dec, 2009 | Pubmed ID: 20221421 Organ-specific Attenuation of Murine Hepatitis Virus Strain A59 by Replacement of Catalytic Residues in the Putative Viral Cyclic Phosphodiesterase Ns2 Journal of Virology. Apr, 2009 | Pubmed ID: 19176619 Murine Coronavirus Mouse Hepatitis Virus is Recognized by MDA5 and Induces Type I Interferon in Brain Macrophages/microglia Journal of Virology. Oct, 2008 | Pubmed ID: 18667505 Priming of CD8+ T Cells During Central Nervous System Infection with a Murine Coronavirus is Strain Dependent Journal of Virology. Jul, 2008 | Pubmed ID: 18417581 Demyelinating and Nondemyelinating Strains of Mouse Hepatitis Virus Differ in Their Neural Cell Tropism Journal of Virology. Jun, 2008 | Pubmed ID: 18385249 Chemokine Expression During Mouse-hepatitis-virus-induced Encephalitis: Contributions of the Spike and Background Genes Journal of Neurovirology. Jan, 2008 | Pubmed ID: 18300071 The SARS-CoV Ferret Model in an Infection-challenge Study Virology. Apr, 2008 | Pubmed ID: 18234270 The Spike Glycoprotein of Murine Coronavirus MHV-JHM Mediates Receptor-independent Infection and Spread in the Central Nervous Systems of Ceacam1a-/- Mice Journal of Virology. Jan, 2008 | Pubmed ID: 18003729 Inhibition of the Alpha/beta Interferon Response by Mouse Hepatitis Virus at Multiple Levels Journal of Virology. Jul, 2007 | Pubmed ID: 17459917 Replicase Genes of Murine Coronavirus Strains A59 and JHM Are Interchangeable: Differences in Pathogenesis Map to the 3' One-third of the Genome Journal of Virology. Jan, 2007 | Pubmed ID: 17079303 Murine Hepatitis Virus Strain 1 Produces a Clinically Relevant Model of Severe Acute Respiratory Syndrome in A/J Mice Journal of Virology. Nov, 2006 | Pubmed ID: 17041219 CD8+ T-cell Priming During a Central Nervous System Infection with Mouse Hepatitis Virus Advances in Experimental Medicine and Biology. 2006 | Pubmed ID: 17037564 Both Spike and Background Genes Contribute to Murine Coronavirus Neurovirulence Journal of Virology. Jul, 2006 | Pubmed ID: 16809289 Endosomal Proteolysis by Cathepsins is Necessary for Murine Coronavirus Mouse Hepatitis Virus Type 2 Spike-mediated Entry Journal of Virology. Jun, 2006 | Pubmed ID: 16731916 Coronavirus Pathogenesis and the Emerging Pathogen Severe Acute Respiratory Syndrome Coronavirus Microbiology and Molecular Biology Reviews : MMBR. Dec, 2005 | Pubmed ID: 16339739 Expression of Hemagglutinin Esterase Protein from Recombinant Mouse Hepatitis Virus Enhances Neurovirulence Journal of Virology. Dec, 2005 | Pubmed ID: 16306577 Enhanced Expression and Purification of Membrane Proteins by SUMO Fusion in Escherichia Coli Journal of Structural and Functional Genomics. 2005 | Pubmed ID: 16211506 Contributions of the Viral Genetic Background and a Single Amino Acid Substitution in an Immunodominant CD8+ T-cell Epitope to Murine Coronavirus Neurovirulence Journal of Virology. Jul, 2005 | Pubmed ID: 15994805 Expression and Purification of SARS Coronavirus Proteins Using SUMO-fusions Protein Expression and Purification. Jul, 2005 | Pubmed ID: 15939295 Murine Coronavirus Evolution in Vivo: Functional Compensation of a Detrimental Amino Acid Substitution in the Receptor Binding Domain of the Spike Glycoprotein Journal of Virology. Jun, 2005 | Pubmed ID: 15919915 Identification of Murine CD8 T Cell Epitopes in Codon-optimized SARS-associated Coronavirus Spike Protein Virology. Apr, 2005 | Pubmed ID: 15823604 Single-amino-acid Substitutions in Open Reading Frame (ORF) 1b-nsp14 and ORF 2a Proteins of the Coronavirus Mouse Hepatitis Virus Are Attenuating in Mice Journal of Virology. Mar, 2005 | Pubmed ID: 15731233 Increased Epitope-specific CD8+ T Cells Prevent Murine Coronavirus Spread to the Spinal Cord and Subsequent Demyelination Journal of Virology. Mar, 2005 | Pubmed ID: 15731231 Coronavirus Replication and Pathogenesis: Implications for the Recent Outbreak of Severe Acute Respiratory Syndrome (SARS), and the Challenge for Vaccine Development Journal of Neurovirology. Apr, 2004 | Pubmed ID: 15204926 Effects of an Epitope-specific CD8+ T-cell Response on Murine Coronavirus Central Nervous System Disease: Protection from Virus Replication and Antigen Spread and Selection of Epitope Escape Mutants Journal of Virology. Feb, 2004 | Pubmed ID: 14722270 SARS: Lessons Learned from Other Coronaviruses Viral Immunology. 2003 | Pubmed ID: 14733734 The Glycosylation Status of the Murine Hepatitis Coronavirus M Protein Affects the Interferogenic Capacity of the Virus in Vitro and Its Ability to Replicate in the Liver but Not the Brain Virology. Aug, 2003 | Pubmed ID: 12919744 Amino Acid Substitutions Within the Heptad Repeat Domain 1 of Murine Coronavirus Spike Protein Restrict Viral Antigen Spread in the Central Nervous System Virology. Aug, 2003 | Pubmed ID: 12919742 Murine Coronavirus-induced Hepatitis: JHM Genetic Background Eliminates A59 Spike-determined Hepatotropism Journal of Virology. Apr, 2003 | Pubmed ID: 12663803 The N-terminal Domain of the Murine Coronavirus Spike Glycoprotein Determines the CEACAM1 Receptor Specificity of the Virus Strain Journal of Virology. Jan, 2003 | Pubmed ID: 12502800 Conformational Changes in the Spike Glycoprotein of Murine Coronavirus Are Induced at 37 Degrees C Either by Soluble Murine CEACAM1 Receptors or by PH 8 Journal of Virology. Jan, 2003 | Pubmed ID: 12502799 The Virulence of Mouse Hepatitis Virus Strain A59 is Not Dependent on Efficient Spike Protein Cleavage and Cell-to-cell Fusion Journal of Neurovirology. Oct, 2002 | Pubmed ID: 12402166 Enhanced Green Fluorescent Protein Expression May Be Used to Monitor Murine Coronavirus Spread in Vitro and in the Mouse Central Nervous System Journal of Neurovirology. Oct, 2002 | Pubmed ID: 12402164 Perforin-mediated CTL Cytolysis Counteracts Direct Cell-cell Spread of Listeria Monocytogenes Journal of Immunology (Baltimore, Md. : 1950). Nov, 2002 | Pubmed ID: 12391238 Systematic Assembly of a Full-length Infectious CDNA of Mouse Hepatitis Virus Strain A59 Journal of Virology. Nov, 2002 | Pubmed ID: 12368349 Murine Coronavirus Spike Glycoprotein Mediates Degree of Viral Spread, Inflammation, and Virus-induced Immunopathology in the Central Nervous System Virology. Sep, 2002 | Pubmed ID: 12359451 Further in Vitro Characterization of Mouse Hepatitis Virus Papain-like Proteinase 1: Cleavage Sequence Requirements Within Pp1a Journal of Neurovirology. Apr, 2002 | Pubmed ID: 11935466 Multiple Regions of the Murine Coronavirus Spike Glycoprotein Influence Neurovirulence Journal of Neurovirology. Oct, 2001 | Pubmed ID: 11582514 Murine Coronavirus Spike Protein Determines the Ability of the Virus to Replicate in the Liver and Cause Hepatitis Journal of Virology. Mar, 2001 | Pubmed ID: 11160748 Demyelination Determinants Map to the Spike Glycoprotein Gene of Coronavirus Mouse Hepatitis Virus Journal of Virology. Oct, 2000 | Pubmed ID: 10982367 Further Requirements for Cleavage by the Murine Coronavirus 3C-like Proteinase: Identification of a Cleavage Site Within ORF1b Virology. Oct, 1999 | Pubmed ID: 10544119 Amino Acid Substitutions Within the Leucine Zipper Domain of the Murine Coronavirus Spike Protein Cause Defects in Oligomerization and the Ability to Induce Cell-to-cell Fusion Journal of Virology. Oct, 1999 | Pubmed ID: 10482565 Pathogenesis of Chimeric MHV4/MHV-A59 Recombinant Viruses: the Murine Coronavirus Spike Protein is a Major Determinant of Neurovirulence Journal of Virology. Sep, 1999 | Pubmed ID: 10438865 Expression of Murine Coronavirus Recombinant Papain-like Proteinase: Efficient Cleavage is Dependent on the Lengths of Both the Substrate and the Proteinase Polypeptides Journal of Virology. Apr, 1999 | Pubmed ID: 10074111 Cellular Reservoirs for Coronavirus Infection of the Brain in Beta2-microglobulin Knockout Mice Pathobiology : Journal of Immunopathology, Molecular and Cellular Biology. 1999 | Pubmed ID: 10023135 Targeted Recombination Within the Spike Gene of Murine Coronavirus Mouse Hepatitis Virus-A59: Q159 is a Determinant of Hepatotropism Journal of Virology. Dec, 1998 | Pubmed ID: 9811696 Roles in Cell-to-cell Fusion of Two Conserved Hydrophobic Regions in the Murine Coronavirus Spike Protein Virology. May, 1998 | Pubmed ID: 9601516 The Spike Protein of Murine Coronavirus Mouse Hepatitis Virus Strain A59 is Not Cleaved in Primary Glial Cells and Primary Hepatocytes Journal of Virology. Feb, 1998 | Pubmed ID: 9445064 Altered Pathogenesis of a Mutant of the Murine Coronavirus MHV-A59 is Associated with a Q159L Amino Acid Substitution in the Spike Protein Virology. Dec, 1997 | Pubmed ID: 9426441 Efficient Autoproteolytic Processing of the MHV-A59 3C-like Proteinase from the Flanking Hydrophobic Domains Requires Membranes Virology. Apr, 1997 | Pubmed ID: 9143287 Syncytia Formation Induced by Coronavirus Infection is Associated with Fragmentation and Rearrangement of the Golgi Apparatus Virology. Jul, 1996 | Pubmed ID: 8661443 Identification and Characterization of a 65-kDa Protein Processed from the Gene 1 Polyprotein of the Murine Coronavirus MHV-A59 Virology. Feb, 1995 | Pubmed ID: 7871746 Mouse Hepatitis Virus A59-induced Demyelination Can Occur in the Absence of CD8+ T Cells Microbial Pathogenesis. Mar, 1995 | Pubmed ID: 7565015 Mouse Hepatitis Virus Strain A59 RNA Polymerase Gene ORF 1a: Heterogeneity Among MHV Strains Virology. Feb, 1994 | Pubmed ID: 8291254 The Ns 4 Gene of Mouse Hepatitis Virus (MHV), Strain A 59 Contains Two ORFs and Thus Differs from Ns 4 of the JHM and S Strains Archives of Virology. 1993 | Pubmed ID: 8385918 Mouse Hepatitis Virus A59 Increases Steady-state Levels of MHC MRNAs in Primary Glial Cell Cultures and in the Murine Central Nervous System Microbial Pathogenesis. Dec, 1992 | Pubmed ID: 1338798 Intracellular Processing of the N-terminal ORF 1a Proteins of the Coronavirus MHV-A59 Requires Multiple Proteolytic Events Virology. Jul, 1992 | Pubmed ID: 1318604 Mouse Hepatitis Virus ORF 2a is Expressed in the Cytosol of Infected Mouse Fibroblasts Virology. Feb, 1990 | Pubmed ID: 2154893 A General Method for the Induction and Screening of Antisera for CDNA-encoded Polypeptides: Antibodies Specific for a Coronavirus Putative Polymerase-encoding Gene Gene. Dec, 1989 | Pubmed ID: 2560756 Molecular Cloning of the Gene Encoding the Putative Polymerase of Mouse Hepatitis Coronavirus, Strain A59 Virology. Jul, 1989 | Pubmed ID: 2545027 Induction of MHC Class I Antigens on Glial Cells is Dependent on Persistent Mouse Hepatitis Virus Infection Journal of Neuroimmunology. Apr, 1989 | Pubmed ID: 2538490 Detection of a Murine Coronavirus Nonstructural Protein Encoded in a Downstream Open Reading Frame Virology. May, 1988 | Pubmed ID: 2834866 In Vitro Synthesis of Two Polypeptides from a Nonstructural Gene of Coronavirus Mouse Hepatitis Virus Strain A59 Virology. Apr, 1987 | Pubmed ID: 3029985 Coronavirus Mouse Hepatitis Virus (MHV)-A59 Causes a Persistent, Productive Infection in Primary Glial Cell Cultures Microbial Pathogenesis. Aug, 1987 | Pubmed ID: 2849019 Coronaviruses SD and SK Share Extensive Nucleotide Homology with Murine Coronavirus MHV-A59, More Than That Shared Between Human and Murine Coronaviruses Virology. Apr, 1983 | Pubmed ID: 6687965 Infection of Primary Nasal Epithelial Cells Grown at an Air-Liquid Interface to Characterize Human Coronavirus-Host Interactions Clayton J. Otter1,2, Alejandra Fausto1,2, Li Hui Tan3,4, Susan R. Weiss1,2, Noam A. Cohen3,4 1Department of Microbiology, University of Pennsylvania, 2Penn Center for Research on Coronaviruses and Other Emerging Pathogens, Perelman School of Medicine, University of Pennsylvania, 3Otorhinolaryngology-Head and Neck Surgery, University of Pennsylvania, 4Corporal Michael J. Crescenz VA Medical Center JoVE 64868 Immunology and Infection
Infection of Primary Nasal Epithelial Cells Grown at an Air-Liquid Interface to Characterize Human Coronavirus-Host Interactions Clayton J. Otter1,2, Alejandra Fausto1,2, Li Hui Tan3,4, Susan R. Weiss1,2, Noam A. Cohen3,4 1Department of Microbiology, University of Pennsylvania, 2Penn Center for Research on Coronaviruses and Other Emerging Pathogens, Perelman School of Medicine, University of Pennsylvania, 3Otorhinolaryngology-Head and Neck Surgery, University of Pennsylvania, 4Corporal Michael J. Crescenz VA Medical Center JoVE 64868 Immunology and Infection