Takahiro Oike Department of Radiation Oncology Gunma University Graduate School of Medicine Biography Publications Institution JoVE Articles Takahiro Oike has not added a biography. If you are Takahiro Oike and would like to personalize this page please email our Author Liaison for assistance. Publications PD-L1 Expression is Mainly Regulated by IFN-γ Associated with JAK-STAT Pathway in Gastric Cancer Cancer Science. Oct, 2017 | Pubmed ID: 29034543 Inhibition of the HDAC/Suv39/G9a Pathway Restores the Expression of DNA Damage-dependent Major Histocompatibility Complex Class I-related Chain A and B in Cancer Cells Oncology Reports. Aug, 2017 | Pubmed ID: 28677817 Mitotic Catastrophe is a Putative Mechanism Underlying the Weak Correlation Between Sensitivity to Carbon Ions and Cisplatin Scientific Reports. Jan, 2017 | Pubmed ID: 28091564 BRCA1 Directs the Repair Pathway to Homologous Recombination by Promoting 53BP1 Dephosphorylation Cell Reports. Jan, 2017 | Pubmed ID: 28076794 In-room Computed Tomography-based Brachytherapy for Uterine Cervical Cancer: Results of a 5-year Retrospective Study Journal of Radiation Research. Jul, 2017 | Pubmed ID: 27986859 Translational Research to Improve the Efficacy of Carbon Ion Radiotherapy: Experience of Gunma University Frontiers in Oncology. 2016 | Pubmed ID: 27376029 Solitary Cardiac Metastasis of Uterine Cervical Cancer with Antemortem Diagnosis: A Case Report and Literature Review Oncology Letters. May, 2016 | Pubmed ID: 27123113 Identification of DNA Double Strand Breaks at Chromosome Boundaries Along the Track of Particle Irradiation Genes, Chromosomes & Cancer. Aug, 2016 | Pubmed ID: 27113385 Visualization of Complex DNA Double-strand Breaks in a Tumor Treated with Carbon Ion Radiotherapy Scientific Reports. Mar, 2016 | Pubmed ID: 26925533 Leptomeningeal Metastasis of Uterine Cervical Cancer 17 Years After Primary Tumor Treatment Clinical Case Reports. Jan, 2016 | Pubmed ID: 26783437 Targeting P300 Addiction in CBP-Deficient Cancers Causes Synthetic Lethality by Apoptotic Cell Death Due to Abrogation of MYC Expression Cancer Discovery. Apr, 2016 | Pubmed ID: 26603525 Polymyositis and Fatal Interstitial Pneumonia Following Pelvic Irradiation That Led to Unexpectedly Severe Adverse Effects: a Case Report Clinical Case Reports. Aug, 2015 | Pubmed ID: 26331019 Carbon-ion Beams Effectively Induce Growth Inhibition and Apoptosis in Human Neural Stem Cells Compared with Glioblastoma A172 Cells Journal of Radiation Research. Sep, 2015 | Pubmed ID: 26070322 The EGFR Mutation Status Affects the Relative Biological Effectiveness of Carbon-ion Beams in Non-small Cell Lung Carcinoma Cells Scientific Reports. Jun, 2015 | Pubmed ID: 26065573 Radio-sensitization Effect of an MTOR Inhibitor, Temsirolimus, on Lung Adenocarcinoma A549 Cells Under Normoxic and Hypoxic Conditions Journal of Radiation Research. Jul, 2015 | Pubmed ID: 25887043 Pre-exposure to Ionizing Radiation Stimulates DNA Double Strand Break End Resection, Promoting the Use of Homologous Recombination Repair PloS One. 2015 | Pubmed ID: 25826455 Carbon-ion Beams Induce Production of an Immune Mediator Protein, High Mobility Group Box 1, at Levels Comparable with X-ray Irradiation Journal of Radiation Research. May, 2015 | Pubmed ID: 25755254 Topics in Chemotherapy, Molecular-targeted Therapy, and Immunotherapy for Newly-diagnosed Glioblastoma Multiforme Anticancer Research. Mar, 2015 | Pubmed ID: 25750269 Radiosensitizing Effect of Carboplatin and Paclitaxel to Carbon-ion Beam Irradiation in the Non-small-cell Lung Cancer Cell Line H460 Journal of Radiation Research. Mar, 2015 | Pubmed ID: 25599995 Carbon-ion Beam Irradiation Kills X-ray-resistant P53-null Cancer Cells by Inducing Mitotic Catastrophe PloS One. 2014 | Pubmed ID: 25531293 Can Combined Intracavitary/interstitial Approach Be an Alternative to Interstitial Brachytherapy with the Martinez Universal Perineal Interstitial Template (MUPIT) in Computed Tomography-guided Adaptive Brachytherapy for Bulky And/or Irregularly Shaped Gynecological Tumors? Radiation Oncology (London, England). Oct, 2014 | Pubmed ID: 25319341 HLA Class I Expression and Its Alteration by Preoperative Hyperthermo-chemoradiotherapy in Patients with Rectal Cancer PloS One. 2014 | Pubmed ID: 25259797 Proposal for a Synthetic Lethality Therapy Using the Paralog Dependence of Cancer Cells--response Cancer Research. Sep, 2014 | Pubmed ID: 25136072 C646, a Selective Small Molecule Inhibitor of Histone Acetyltransferase P300, Radiosensitizes Lung Cancer Cells by Enhancing Mitotic Catastrophe Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology. May, 2014 | Pubmed ID: 24746574 Radiotherapy-induced Anti-tumor Immunity Contributes to the Therapeutic Efficacy of Irradiation and Can Be Augmented by CTLA-4 Blockade in a Mouse Model PloS One. 2014 | Pubmed ID: 24686897 Increase in Cell Motility by Carbon Ion Irradiation Via the Rho Signaling Pathway and Its Inhibition by the ROCK Inhibitor Y-27632 in Lung Adenocarcinoma A549 Cells Journal of Radiation Research. Jul, 2014 | Pubmed ID: 24659807 Chromatin-regulating Proteins As Targets for Cancer Therapy Journal of Radiation Research. Jul, 2014 | Pubmed ID: 24522270 Radiotherapy Plus Concomitant Adjuvant Temozolomide for Glioblastoma: Japanese Mono-institutional Results PloS One. 2013 | Pubmed ID: 24265731 Changes in Bone Mineral Density in Uterine Cervical Cancer Patients After Radiation Therapy International Journal of Radiation Oncology, Biology, Physics. Dec, 2013 | Pubmed ID: 24139516 Inactivating Mutations in SWI/SNF Chromatin Remodeling Genes in Human Cancer Japanese Journal of Clinical Oncology. Sep, 2013 | Pubmed ID: 23904343 A Synthetic Lethality-based Strategy to Treat Cancers Harboring a Genetic Deficiency in the Chromatin Remodeling Factor BRG1 Cancer Research. Sep, 2013 | Pubmed ID: 23872584 Comparison of Hematological Toxicities Between Innovator and Generic Cisplatin Formulations in Cervical Cancer Patients Treated with Concurrent Chemoradiotherapy Journal of Radiation Research. May, 2013 | Pubmed ID: 23242248 Suppression of HIF-1α Expression and Radiation Resistance in Acute Hypoxic Conditions Experimental and Therapeutic Medicine. Jan, 2012 | Pubmed ID: 22969859 Garcinol, a Histone Acetyltransferase Inhibitor, Radiosensitizes Cancer Cells by Inhibiting Non-homologous End Joining International Journal of Radiation Oncology, Biology, Physics. Nov, 2012 | Pubmed ID: 22417805 KIF5B-RET Fusions in Lung Adenocarcinoma Nature Medicine. Feb, 2012 | Pubmed ID: 22327624 The Benefit of Small Bowel and Pelvic Bone Sparing in Excluding Common Iliac Lymph Node Region from Conventional Radiation Fields in Patients with Uterine Cervical Cancer: a Dosimetric Study Journal of Radiation Research. 2010 | Pubmed ID: 20972366 One-step Protocol for Evaluation of the Mode of Radiation-induced Clonogenic Cell Death by Fluorescence Microscopy Daijiro Kobayashi1, Atsushi Shibata2, Takahiro Oike1, Takashi Nakano1 1Department of Radiation Oncology, Gunma University Graduate School of Medicine, 2Advanced Scientific Research Leaders Development Unit, Gunma University Graduate School of Medicine JoVE 56338 Cancer Research
One-step Protocol for Evaluation of the Mode of Radiation-induced Clonogenic Cell Death by Fluorescence Microscopy Daijiro Kobayashi1, Atsushi Shibata2, Takahiro Oike1, Takashi Nakano1 1Department of Radiation Oncology, Gunma University Graduate School of Medicine, 2Advanced Scientific Research Leaders Development Unit, Gunma University Graduate School of Medicine JoVE 56338 Cancer Research
