Takato Takenouchi Transgenic Animal Research Center National Institute of Agrobiological Sciences, Tsukuba, Japan Biography Publications Institution JoVE Articles Takato Takenouchi has not added a biography. If you are Takato Takenouchi and would like to personalize this page please email our Author Liaison for assistance. Publications Critical Roles of the WASP N-Terminal Domain and Btk in LPS-Induced Inflammatory Response in Macrophages PloS One. 2012 | Pubmed ID: 22253930 Carnosic Acid, a Pro-electrophilic Compound, Inhibits LPS-induced Activation of Microglia Biochemical and Biophysical Research Communications. Feb, 2012 | Pubmed ID: 22214931 Identification of Fyn As the Binding Partner for the WASP N-terminal Domain in T Cells International Immunology. Aug, 2011 | Pubmed ID: 21705469 The Activation of P2X7 Receptor Induces Cathepsin D-dependent Production of a 20-kDa Form of IL-1β Under Acidic Extracellular PH in LPS-primed Microglial Cells Journal of Neurochemistry. May, 2011 | Pubmed ID: 21395581 Isolation and Characterization of Macrophages from a Mixed Primary Culture of Bovine Liver Cells Veterinary Immunology and Immunopathology. Apr, 2011 | Pubmed ID: 21334751 Angiopoietin-1/Tie2 Signal Augments Basal Notch Signal Controlling Vascular Quiescence by Inducing Delta-like 4 Expression Through AKT-mediated Activation of Beta-catenin The Journal of Biological Chemistry. Mar, 2011 | Pubmed ID: 21212269 Cold Stress Induced Morphological Microglial Activation and Increased IL-1β Expression in Astroglial Cells in Rat Brain Journal of Neuroimmunology. Apr, 2011 | Pubmed ID: 21115202 A β-synuclein Mutation Linked to Dementia Produces Neurodegeneration when Expressed in Mouse Brain Nature Communications. 2010 | Pubmed ID: 21045828 A Novel Isolation Method for Macrophage-like Cells from Mixed Primary Cultures of Adult Rat Liver Cells Journal of Immunological Methods. Aug, 2010 | Pubmed ID: 20600081 P2X7 Receptor Signaling Pathway As a Therapeutic Target for Neurodegenerative Diseases Archivum Immunologiae Et Therapiae Experimentalis. Apr, 2010 | Pubmed ID: 20143170 Gamma-Irradiation Induces P2X(7) Receptor-dependent ATP Release from B16 Melanoma Cells Biochimica Et Biophysica Acta. Jan, 2010 | Pubmed ID: 19854240 Possible Roles of Microglial Cells for Neurotoxicity in Clinical Neurodegenerative Diseases and Experimental Animal Models Inflammation & Allergy Drug Targets. Sep, 2009 | Pubmed ID: 19754411 Modulation of the ATP-lnduced Release and Processing of IL-1beta in Microglial Cells Critical Reviews in Immunology. 2009 | Pubmed ID: 19673687 Protective Role of Endogenous Gangliosides for Lysosomal Pathology in a Cellular Model of Synucleinopathies The American Journal of Pathology. May, 2009 | Pubmed ID: 19349362 The Role of the P2X7 Receptor Signaling Pathway for the Release of Autolysosomes in Microglial Cells Autophagy. Jul, 2009 | Pubmed ID: 19337025 The Activation of P2X7 Receptor Impairs Lysosomal Functions and Stimulates the Release of Autophagolysosomes in Microglial Cells Journal of Immunology (Baltimore, Md. : 1950). Feb, 2009 | Pubmed ID: 19201858 Microglial Activation is Inhibited by Corticosterone in Dopaminergic Neurodegeneration Journal of Neuroimmunology. Mar, 2009 | Pubmed ID: 19201037 Differential Microglial Activation Between Acute Stress and Lipopolysaccharide Treatment Journal of Neuroimmunology. Feb, 2009 | Pubmed ID: 19111355 Establishment of an SV40 Large T Antigen-immortalized Bovine Brain Cell Line and Its Neuronal Differentiation by Dibutyryl-cyclic AMP Cell Biology International. Feb, 2009 | Pubmed ID: 19032985 Lactoferrin Induces Cell Surface Retention of Prion Protein and Inhibits Prion Accumulation Journal of Neurochemistry. Nov, 2008 | Pubmed ID: 18717818 [Establishment and Characterization of Prion-infected Microglial Cells] Seikagaku. The Journal of Japanese Biochemical Society. Jul, 2008 | Pubmed ID: 18712065 Lysophospholipids and ATP Mutually Suppress Maturation and Release of IL-1 Beta in Mouse Microglial Cells Using a Rho-dependent Pathway Journal of Immunology (Baltimore, Md. : 1950). Jun, 2008 | Pubmed ID: 18523246 Activin As an Anti-inflammatory Cytokine Produced by Microglia Journal of Neuroimmunology. Dec, 2007 | Pubmed ID: 17976743 Prion Infection Correlates with Hypersensitivity of P2X7 Nucleotide Receptor in a Mouse Microglial Cell Line FEBS Letters. Jun, 2007 | Pubmed ID: 17544414 Lysophosphatidylcholine Potentiates Ca2+ Influx, Pore Formation and P44/42 MAP Kinase Phosphorylation Mediated by P2X7 Receptor Activation in Mouse Microglial Cells Journal of Neurochemistry. Sep, 2007 | Pubmed ID: 17437542 Alpha-Synuclein Stimulates Differentiation of Osteosarcoma Cells: Relevance to Down-regulation of Proteasome Activity The Journal of Biological Chemistry. Feb, 2007 | Pubmed ID: 17189270 Microglial Cell Line Established from Prion Protein-overexpressing Mice is Susceptible to Various Murine Prion Strains Journal of Virology. Feb, 2007 | Pubmed ID: 17121794 Establishment and Characterization of SV40 Large T Antigen-immortalized Cell Lines Derived from Fetal Bovine Brain Tissues After Prolonged Cryopreservation Cell Biology International. Jan, 2007 | Pubmed ID: 17049468 Inhibitory Effects of U73122 and U73343 on Ca2+ Influx and Pore Formation Induced by the Activation of P2X7 Nucleotide Receptors in Mouse Microglial Cell Line Biochimica Et Biophysica Acta. Nov, 2005 | Pubmed ID: 16122875 Role of Caveolin-1 and Cytoskeletal Proteins, Actin and Vimentin, in Adipogenesis of Bovine Intramuscular Preadipocyte Cells Cell Biology International. 2004 | Pubmed ID: 15350596 Beta-synuclein Regulates Akt Activity in Neuronal Cells. A Possible Mechanism for Neuroprotection in Parkinson's Disease The Journal of Biological Chemistry. May, 2004 | Pubmed ID: 15026413 Co-treatment with Dexamethasone and Octanoate Induces Adipogenesis in 3T3-L1 Cells Cell Biology International. 2004 | Pubmed ID: 14984747 Alpha-synuclein Up-regulates Expression of Caveolin-1 and Down-regulates Extracellular Signal-regulated Kinase Activity in B103 Neuroblastoma Cells: Role in the Pathogenesis of Parkinson's Disease Journal of Neurochemistry. Jun, 2003 | Pubmed ID: 12787066 The Chemical Synthesis and Binding Affinity to the EGF Receptor of the EGF-like Domain of Heparin-binding EGF-like Growth Factor (HB-EGF) Journal of Peptide Science : an Official Publication of the European Peptide Society. Apr, 2003 | Pubmed ID: 12725245 Cell Culture on Thin Tissue Sections Commonly Prepared for Histopathology FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Nov, 2002 | Pubmed ID: 12223453 Alpha-Synuclein Protects Against Oxidative Stress Via Inactivation of the C-Jun N-terminal Kinase Stress-signaling Pathway in Neuronal Cells The Journal of Biological Chemistry. Mar, 2002 | Pubmed ID: 11790792 Yetişkin Karaciğer Hücrelerinin Karma İlköğretim Kültürler Makrofajlar yalıtın Basit ve Etkin Yöntem Hiroshi Kitani1, Takato Takenouchi1, Mitsuru Sato1, Miyako Yoshioka2, Noriko Yamanaka2 1Transgenic Animal Research Center, National Institute of Agrobiological Sciences, Tsukuba, Japan, 2Safety Research Team, National Institute of Animal Health, Tsukuba, Japan JoVE 2757 Immunology and Infection
Yetişkin Karaciğer Hücrelerinin Karma İlköğretim Kültürler Makrofajlar yalıtın Basit ve Etkin Yöntem Hiroshi Kitani1, Takato Takenouchi1, Mitsuru Sato1, Miyako Yoshioka2, Noriko Yamanaka2 1Transgenic Animal Research Center, National Institute of Agrobiological Sciences, Tsukuba, Japan, 2Safety Research Team, National Institute of Animal Health, Tsukuba, Japan JoVE 2757 Immunology and Infection