Articles by Thomas J. Burton in JoVE
Behavioral Assessment of the Aging Mouse Vestibular System Victoria W. K. Tung1, Thomas J. Burton2, Edward Dababneh1, Stephanie L. Quail1, Aaron J. Camp1 1Discipline of Biomedical Science, University of Sydney, 2The Bosch Institute Animal Behavioural Facility, University of Sydney Motor control and balance performance are known to deteriorate with age. This paper presents a number of standard noninvasive behavioral tests with the addition of a simple rotary stimulus to challenge the vestibular system and show changes in balance performance in a murine model of aging.
The Use of the Puzzle Box as a Means of Assessing the Efficacy of Environmental Enrichment Angela M. O'Connor1, Thomas J. Burton1,2, Catherine A. Leamey1, Atomu Sawatari1 1Discipline of Physiology, University of Sydney, 2Bosch Animal Behavioural Facility, University of Sydney Environmental enrichment provides a potential protective effect against neurodegenerative disorders. Currently, however, there is no easy way of determining the efficacy of enrichment procedures. This protocol describes a simple “Puzzle Box” method for assessing an animal’s cognitive function, in order to reveal the effectiveness of environmental enrichment.