Thomas W. Claydon Department of Biomedical Physiology and Kinesiology Simon Fraser University Biography Publications Institution JoVE Articles Thomas W. Claydon has not added a biography. If you are Thomas W. Claydon and would like to personalize this page please email our Author Liaison for assistance. Publications Ion Channel Model Reduction Using Manifold Boundaries Journal of the Royal Society, Interface. Aug, 2022 | Pubmed ID: 35946166 Electrophysiological Characterization of the HERG R56Q LQTS Variant and Targeted Rescue by the Activator RPR260243 The Journal of General Physiology. 10, 2021 | Pubmed ID: 34398210 The HERG Channel Activator, RPR260243, Enhances Protective Current Early in the Refractory Period Reducing Arrhythmogenicity in Zebrafish Hearts American Journal of Physiology. Heart and Circulatory Physiology. 08, 2020 | Pubmed ID: 32559136 Modulation of HERG K Channel Deactivation by Voltage Sensor Relaxation Frontiers in Pharmacology. 2020 | Pubmed ID: 32184724 Extracellular Protons Accelerate HERG Channel Deactivation by Destabilizing Voltage Sensor Relaxation The Journal of General Physiology. 02, 2019 | Pubmed ID: 30530765 Investigating the State Dependence of Drug Binding in HERG Channels Using a Trapped-open Channel Phenotype Scientific Reports. 03, 2018 | Pubmed ID: 29563525 Functional Characterization of a Novel HERG Variant in a Family with Recurrent Sudden Infant Death Syndrome: Retracting a Genetic Diagnosis Forensic Science International. Mar, 2018 | Pubmed ID: 29331839 Loss-of-Function and Gain-of-Function Mutations in KCNQ5 Cause Intellectual Disability or Epileptic Encephalopathy American Journal of Human Genetics. Jul, 2017 | Pubmed ID: 28669405 Stabilization of the Activated HERG Channel Voltage Sensor by Depolarization Involves the S4-S5 Linker Biophysical Journal. Jan, 2017 | Pubmed ID: 28122216 The Zebrafish Heart As a Model of Mammalian Cardiac Function Reviews of Physiology, Biochemistry and Pharmacology. 2016 | Pubmed ID: 27538987 Proline Scan of the HERG Channel S6 Helix Reveals the Location of the Intracellular Pore Gate Biophysical Journal. Mar, 2014 | Pubmed ID: 24606930 Closed-state Inactivation Induced in K(V)1 Channels by Extracellular Acidification Channels (Austin, Tex.). Mar-Apr, 2008 | Pubmed ID: 18849651 CRISPR-Cas9を介したゼブラフィッシュハートの正確なノックイン編集 Kyle E. Simpson1, Shoaib Faizi1, Ravichandra Venkateshappa1, Mandy Yip1, Raj Johal1, Damon Poburko1, Yen May Cheng1, Diana Hunter1, Eric Lin1, Glen F. Tibbits1, Thomas W. Claydon1 1Department of Biomedical Physiology and Kinesiology, Simon Fraser University JoVE 64209 Biology
CRISPR-Cas9を介したゼブラフィッシュハートの正確なノックイン編集 Kyle E. Simpson1, Shoaib Faizi1, Ravichandra Venkateshappa1, Mandy Yip1, Raj Johal1, Damon Poburko1, Yen May Cheng1, Diana Hunter1, Eric Lin1, Glen F. Tibbits1, Thomas W. Claydon1 1Department of Biomedical Physiology and Kinesiology, Simon Fraser University JoVE 64209 Biology
