Wen Bu Lester & Sue Smith Breast Center Baylor College of Medicine Biography Publications Institution JoVE Articles Wen Bu has not added a biography. If you are Wen Bu and would like to personalize this page please email our Author Liaison for assistance. Publications Short-term PI3K Inhibition Prevents Breast Cancer in Preclinical Models Cancer Prevention Research (Philadelphia, Pa.). Feb, 2023 | Pubmed ID: 36343340 High-throughput Profiling of Histone Post-translational Modifications and Chromatin Modifying Proteins by Reverse Phase Protein Array Journal of Proteomics. Jun, 2022 | Pubmed ID: 35489683 Targeting the Pro-survival Protein BCL-2 to Prevent Breast Cancer Cancer Prevention Research (Philadelphia, Pa.). Jan, 2022 | Pubmed ID: 34667127 Intraductal Injection of Lentivirus Vectors for Stably Introducing Genes into Rat Mammary Epithelial Cells in Vivo Journal of Mammary Gland Biology and Neoplasia. Dec, 2020 | Pubmed ID: 33165800 Immuno-subtyping of Breast Cancer Reveals Distinct Myeloid Cell Profiles and Immunotherapy Resistance Mechanisms Nature Cell Biology. 09, 2019 | Pubmed ID: 31451770 Mammary Precancerous Stem and Non-Stem Cells Evolve into Cancers of Distinct Subtypes Cancer Research. 01, 2019 | Pubmed ID: 30401712 Pharmacological Targeting of MYC-regulated IRE1/XBP1 Pathway Suppresses MYC-driven Breast Cancer The Journal of Clinical Investigation. 04, 2018 | Pubmed ID: 29480818 Breast Tumor Cell-specific Knockout of Inhibits Cancer Cell Plasticity, Dissemination, and Lung Metastasis in Mice Proceedings of the National Academy of Sciences of the United States of America. Oct, 2017 | Pubmed ID: 29073077 Targeting Oncogenes into a Defined Subset of Mammary Cells Demonstrates That the Initiating Oncogenic Mutation Defines the Resulting Tumor Phenotype International Journal of Biological Sciences. 2016 | Pubmed ID: 27019623 Luminal Epithelial Cells Within the Mammary Gland Can Produce Basal Cells Upon Oncogenic Stress Oncogene. Mar, 2016 | Pubmed ID: 26096929 Wild-Type N-Ras, Overexpressed in Basal-like Breast Cancer, Promotes Tumor Formation by Inducing IL-8 Secretion Via JAK2 Activation Cell Reports. Jul, 2015 | Pubmed ID: 26166574 Krt6a-positive Mammary Epithelial Progenitors Are Not at Increased Vulnerability to Tumorigenesis Initiated by ErbB2 PloS One. 2015 | Pubmed ID: 25635772 STAT3 Signaling is Activated Preferentially in Tumor-initiating Cells in Claudin-low Models of Human Breast Cancer Stem Cells (Dayton, Ohio). Oct, 2014 | Pubmed ID: 24891218 Wnt-responsive Cancer Stem Cells Are Located Close to Distorted Blood Vessels and Not in Hypoxic Regions in a P53-null Mouse Model of Human Breast Cancer Stem Cells Translational Medicine. Jul, 2014 | Pubmed ID: 24797826 Amplification and Over-expression of MAP3K3 Gene in Human Breast Cancer Promotes Formation and Survival of Breast Cancer Cells The Journal of Pathology. Jan, 2014 | Pubmed ID: 24122835 Mammary Cells with Active Wnt Signaling Resist ErbB2-induced Tumorigenesis PloS One. 2013 | Pubmed ID: 24265712 Differential Regulation of C-Jun Protein Plays an Instrumental Role in Chemoresistance of Cancer Cells The Journal of Biological Chemistry. Jul, 2013 | Pubmed ID: 23678002 A Novel Role of Hematopoietic CCL5 in Promoting Triple-negative Mammary Tumor Progression by Regulating Generation of Myeloid-derived Suppressor Cells Cell Research. Mar, 2013 | Pubmed ID: 23266888 EGFR-induced and PKCε Monoubiquitylation-dependent NF-κB Activation Upregulates PKM2 Expression and Promotes Tumorigenesis Molecular Cell. Dec, 2012 | Pubmed ID: 23123196 Keratin 6a Marks Mammary Bipotential Progenitor Cells That Can Give Rise to a Unique Tumor Model Resembling Human Normal-like Breast Cancer Oncogene. Oct, 2011 | Pubmed ID: 21532625 Defining the ATM-mediated Barrier to Tumorigenesis in Somatic Mammary Cells Following ErbB2 Activation Proceedings of the National Academy of Sciences of the United States of America. Feb, 2010 | Pubmed ID: 20133707 Lentivirus Vectors for Stably Introducing Genes into Mammary Epithelial Cells in Vivo Journal of Mammary Gland Biology and Neoplasia. Dec, 2009 | Pubmed ID: 19936990 Lentivirus-mediated Oncogene Introduction into Mammary Cells in Vivo Induces Tumors Neoplasia (New York, N.Y.). Jul, 2008 | Pubmed ID: 18592025 Keratin 6 is Not Essential for Mammary Gland Development Breast Cancer Research : BCR. 2006 | Pubmed ID: 16790075 In Vivo Gene Delivery into Mouse Mammary Epithelial Cells Through Mammary Intraductal Injection Wen Bu1,2, Yi Li1,3 1Lester & Sue Smith Breast Center, Baylor College of Medicine, 2Department of Medicine, Baylor College of Medicine, 3Department of Molecular & Cellular Biology, Baylor College of Medicine, Houston, TX 77030 JoVE 64718 Cancer Research
In Vivo Gene Delivery into Mouse Mammary Epithelial Cells Through Mammary Intraductal Injection Wen Bu1,2, Yi Li1,3 1Lester & Sue Smith Breast Center, Baylor College of Medicine, 2Department of Medicine, Baylor College of Medicine, 3Department of Molecular & Cellular Biology, Baylor College of Medicine, Houston, TX 77030 JoVE 64718 Cancer Research
