Yi Li

Publications

• Generation of a Tree Shrew Breast Cancer Model Using Lentivirus Expressing -
  Zoological Research. Jan, 2023  |   Pubmed ID: 36376241
• Short-term PI3K Inhibition Prevents Breast Cancer in Preclinical Models
  Cancer Prevention Research (Philadelphia, Pa.). Feb, 2023  |   Pubmed ID: 36343340
• STAT5 Confers Lactogenic Properties in Breast Tumorigenesis and Restricts Metastatic Potential
  Oncogene. Nov, 2022  |   Pubmed ID: 36261627
• Low-dose Carbon Monoxide Suppresses Metastatic Progression of Disseminated Cancer Cells
  Cancer Letters. Oct, 2022  |   Pubmed ID: 35868533
• A Large-Scale Genome-Wide Gene-Gene Interaction Study of Lung Cancer Susceptibility in Europeans With a Trans-Ethnic Validation in Asians
  Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer. Aug, 2022  |   Pubmed ID: 35500836
• High-throughput Profiling of Histone Post-translational Modifications and Chromatin Modifying Proteins by Reverse Phase Protein Array
  Journal of Proteomics. Jun, 2022  |   Pubmed ID: 35489683
• Common Genomic Aberrations in Mouse and Human Breast Cancers with Concurrent P53 Deficiency and Activated PTEN-PI3K-AKT Pathway
  International Journal of Biological Sciences. 2022  |   Pubmed ID: 34975329
• RSPO2 and RANKL Signal Through LGR4 to Regulate Osteoclastic Premetastatic Niche Formation and Bone Metastasis
  The Journal of Clinical Investigation. Jan, 2022  |   Pubmed ID: 34847079
• Targeting the Pro-survival Protein BCL-2 to Prevent Breast Cancer
  Cancer Prevention Research (Philadelphia, Pa.). Jan, 2022  |   Pubmed ID: 34667127
• A Wnt-Independent LGR4-EGFR Signaling Axis in Cancer Metastasis
  Cancer Research. Sep, 2021  |   Pubmed ID: 34099494
• Cell Lineage Tracing Links ERα Loss in Erbb2-positive Breast Cancers to the Arising of a Highly Aggressive Breast Cancer Subtype
  Proceedings of the National Academy of Sciences of the United States of America. May, 2021  |   Pubmed ID: 34006643
• The Bone Microenvironment Invigorates Metastatic Seeds for Further Dissemination
  Cell. Apr, 2021  |   Pubmed ID: 33878291
• Deep Learning Applied to Two-dimensional Color Doppler Flow Imaging Ultrasound Images Significantly Improves Diagnostic Performance in the Classification of Breast Masses: a Multicenter Study
  Chinese Medical Journal. Jan, 2021  |   Pubmed ID: 33617184
• Author Correction: ALK Phosphorylates SMAD4 on Tyrosine to Disable TGF-β Tumour Suppressor Functions
  Nature Cell Biology. Mar, 2021  |   Pubmed ID: 33531669
• P53 Promoted Ferroptosis in Ovarian Cancer Cells Treated with Human Serum Incubated-Superparamagnetic Iron Oxides
  International Journal of Nanomedicine. 2021  |   Pubmed ID: 33469287
• Metformin and an Insulin/IGF-1 Receptor Inhibitor Are Synergistic in Blocking Growth of Triple-negative Breast Cancer
  Breast Cancer Research and Treatment. Jan, 2021  |   Pubmed ID: 32940848
• Functional Impact of Cancer Patient-associated Bcl-xL Mutations
  MedComm. Dec, 2020  |   Pubmed ID: 34308416
• Intraductal Injection of Lentivirus Vectors for Stably Introducing Genes into Rat Mammary Epithelial Cells in Vivo
  Journal of Mammary Gland Biology and Neoplasia. Dec, 2020  |   Pubmed ID: 33165800
• Incorporation of Metal-organic Frameworks into Electrospun Chitosan/poly (vinyl Alcohol) Nanofibrous Membrane with Enhanced Antibacterial Activity for Wound Dressing Application
  International Journal of Biological Macromolecules. Apr, 2020  |   Pubmed ID: 32353508
• A POMC-originated Circuit Regulates Stress-induced Hypophagia, Depression, and Anhedonia
  Molecular Psychiatry. 05, 2020  |   Pubmed ID: 31485012
• Immuno-subtyping of Breast Cancer Reveals Distinct Myeloid Cell Profiles and Immunotherapy Resistance Mechanisms
  Nature Cell Biology. 09, 2019  |   Pubmed ID: 31451770
• PTPN3 Acts As a Tumor Suppressor and Boosts TGF-β Signaling Independent of Its Phosphatase Activity
  The EMBO Journal. 07, 2019  |   Pubmed ID: 31304624
• Heterozygosity Mapping for Human Dominant Trait Variants
  Human Mutation. Jul, 2019  |   Pubmed ID: 31018026
• Knocking Down MiR-384 Promotes Growth and Metastasis of Osteosarcoma MG63 Cells by Targeting SLBP
  Artificial Cells, Nanomedicine, and Biotechnology. Dec, 2019  |   Pubmed ID: 31007083
• MicroRNA-203 Promotes Proliferation, Differentiation, and Migration of Osteoblasts by Upregulation of Msh Homeobox 2
  Journal of Cellular Physiology. 08, 2019  |   Pubmed ID: 30854680
• ALK Phosphorylates SMAD4 on Tyrosine to Disable TGF-β Tumour Suppressor Functions
  Nature Cell Biology. Feb, 2019  |   Pubmed ID: 30664791
• Mammary Precancerous Stem and Non-Stem Cells Evolve into Cancers of Distinct Subtypes
  Cancer Research. 01, 2019  |   Pubmed ID: 30401712
• Gingerenone A Sensitizes the Insulin Receptor and Increases Glucose Uptake by Inhibiting the Activity of P70 S6 Kinase
  Molecular Nutrition & Food Research. Dec, 2018  |   Pubmed ID: 30296358
• SCUBE2 Inhibits the Proliferation, Migration and Invasion of Human Non-small Cell Lung Cancer Cells Through Regulation of the Sonic Hedgehog Signaling Pathway
  Gene. Sep, 2018  |   Pubmed ID: 29883759
• PBX1 Promotes the Cell Proliferation Via JAK2/STAT3 Signaling in Clear Cell Renal Carcinoma
  Biochemical and Biophysical Research Communications. 06, 2018  |   Pubmed ID: 29678569
• Inhibition of P70 S6 Kinase Activity by A77 1726 Induces Autophagy and Enhances the Degradation of Superoxide Dismutase 1 (SOD1) Protein Aggregates
  Cell Death & Disease. Mar, 2018  |   Pubmed ID: 29540819
• LGR4 Modulates Breast Cancer Initiation, Metastasis, and Cancer Stem Cells
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. May, 2018  |   Pubmed ID: 29269400
• Bladder Cancer: Detection and Image Quality Compared Among IShim, RESOLVE, and Ss-EPI Diffusion-weighted MR Imaging with High B Value at 3.0 T MRI
  Medicine. Dec, 2017  |   Pubmed ID: 29390388
• Sonic Hedgehog Signaling in Thyroid Cancer
  Frontiers in Endocrinology. 2017  |   Pubmed ID: 29163356
• The Histone Demethylase Kdm3a is Required for Normal Epithelial Proliferation, Ductal Elongation and Tumor Growth in the Mouse Mammary Gland
  Oncotarget. Oct, 2017  |   Pubmed ID: 29156681
• Breast Tumor Cell-specific Knockout of Inhibits Cancer Cell Plasticity, Dissemination, and Lung Metastasis in Mice
  Proceedings of the National Academy of Sciences of the United States of America. Oct, 2017  |   Pubmed ID: 29073077
• Comparative Risk of New-onset Diabetes Mellitus for Antihypertensive Drugs: A Network Meta-analysis
  Journal of Clinical Hypertension (Greenwich, Conn.). Dec, 2017  |   Pubmed ID: 29067768
• Smad7 Enables STAT3 Activation and Promotes Pluripotency Independent of TGF-β Signaling
  Proceedings of the National Academy of Sciences of the United States of America. Sep, 2017  |   Pubmed ID: 28874583
• A Versatile Tumor Gene Deletion System Reveals a Crucial Role for FGFR1 in Breast Cancer Metastasis
  Neoplasia (New York, N.Y.). May, 2017  |   Pubmed ID: 28433771
• Inhibition of P70 S6 Kinase (S6K1) Activity by A77 1726, the Active Metabolite of Leflunomide, Induces Autophagy Through TAK1-mediated AMPK and JNK Activation
  Oncotarget. May, 2017  |   Pubmed ID: 28389629
• APP Modulates KCC2 Expression and Function in Hippocampal GABAergic Inhibition
  ELife. Jan, 2017  |   Pubmed ID: 28054918
• Loss of Glutaredoxin 3 Impedes Mammary Lobuloalveolar Development During Pregnancy and Lactation
  American Journal of Physiology. Endocrinology and Metabolism. Mar, 2017  |   Pubmed ID: 27894063
• Transurethral Biopsy of the Prostatic Urethra is Associated with Final Apical Margin Status at Radical Cystoprostatectomy
  Journal of Clinical Urology. Nov, 2016  |   Pubmed ID: 27818773
• Xanthine Oxidoreductase is Required for Genotoxic Stress-induced NKG2D Ligand Expression and Gemcitabine-mediated Antitumor Activity
  Oncotarget. Sep, 2016  |   Pubmed ID: 27494876
• Oncogenic MTOR Signalling Recruits Myeloid-derived Suppressor Cells to Promote Tumour Initiation
  Nature Cell Biology. Jun, 2016  |   Pubmed ID: 27183469
• Targeting Oncogenes into a Defined Subset of Mammary Cells Demonstrates That the Initiating Oncogenic Mutation Defines the Resulting Tumor Phenotype
  International Journal of Biological Sciences. 2016  |   Pubmed ID: 27019623
• The Sonic Hedgehog Signaling Pathway Stimulates Anaplastic Thyroid Cancer Cell Motility and Invasiveness by Activating Akt and C-Met
  Oncotarget. Mar, 2016  |   Pubmed ID: 26859575
• Bcl-xL Promotes Metastasis Independent of Its Anti-apoptotic Activity
  Nature Communications. Jan, 2016  |   Pubmed ID: 26785948
• Generation and Characterization of a Breast Carcinoma Model by PyMT Overexpression in Mammary Epithelial Cells of Tree Shrew, an Animal Close to Primates in Evolution
  International Journal of Cancer. Feb, 2016  |   Pubmed ID: 26296387
• Landscape of Dietary Factors Associated with Risk of Gastric Cancer: A Systematic Review and Dose-response Meta-analysis of Prospective Cohort Studies
  European Journal of Cancer (Oxford, England : 1990). Dec, 2015  |   Pubmed ID: 26589974
• NCOA1 Promotes Angiogenesis in Breast Tumors by Simultaneously Enhancing Both HIF1α- and AP-1-mediated VEGFa Transcription
  Oncotarget. Sep, 2015  |   Pubmed ID: 26287601
• Wild-Type N-Ras, Overexpressed in Basal-like Breast Cancer, Promotes Tumor Formation by Inducing IL-8 Secretion Via JAK2 Activation
  Cell Reports. Jul, 2015  |   Pubmed ID: 26166574
• The Status of STAT3 and STAT5 in Human Breast Atypical Ductal Hyperplasia
  PloS One. 2015  |   Pubmed ID: 26146825
• Krt6a-positive Mammary Epithelial Progenitors Are Not at Increased Vulnerability to Tumorigenesis Initiated by ErbB2
  PloS One. 2015  |   Pubmed ID: 25635772
• A P53/ARF-dependent Anticancer Barrier Activates Senescence and Blocks Tumorigenesis Without Impacting Apoptosis
  Molecular Cancer Research : MCR. Feb, 2015  |   Pubmed ID: 25253740
• Inhibition of P70 S6 Kinase (S6K1) Activity by A77 1726 and Its Effect on Cell Proliferation and Cell Cycle Progress
  Neoplasia (New York, N.Y.). Oct, 2014  |   Pubmed ID: 25379019
• NCOA1 Directly Targets M-CSF1 Expression to Promote Breast Cancer Metastasis
  Cancer Research. Jul, 2014  |   Pubmed ID: 24769444
• Pttg1/securin is Required for the Branching Morphogenesis of the Mammary Gland and Suppresses Mammary Tumorigenesis
  Proceedings of the National Academy of Sciences of the United States of America. Jan, 2014  |   Pubmed ID: 24395789
• Mechanism and Preclinical Prevention of Increased Breast Cancer Risk Caused by Pregnancy
  ELife. Dec, 2013  |   Pubmed ID: 24381245
• Mammary Cells with Active Wnt Signaling Resist ErbB2-induced Tumorigenesis
  PloS One. 2013  |   Pubmed ID: 24265712
• MicroRNA-122 Promotes Proliferation, Invasion and Migration of Renal Cell Carcinoma Cells Through the PI3K/Akt Signaling Pathway
  Asian Pacific Journal of Cancer Prevention : APJCP. 2013  |   Pubmed ID: 24175769
• Stem Cell Antigen-1 (sca-1) Regulates Mammary Tumor Development and Cell Migration
  PloS One. 2011  |   Pubmed ID: 22140470
• ID4 Regulates Mammary Gland Development by Suppressing P38MAPK Activity
  Development (Cambridge, England). Dec, 2011  |   Pubmed ID: 22069192
• Oncogene-induced Senescence and Its Role in Tumor Suppression
  Journal of Mammary Gland Biology and Neoplasia. Sep, 2011  |   Pubmed ID: 21681694
• Altered Differentiation and Paracrine Stimulation of Mammary Epithelial Cell Proliferation by Conditionally Activated Smoothened
  Developmental Biology. Apr, 2011  |   Pubmed ID: 21276786
• Somatic Expression of PyMT or Activated ErbB2 Induces Estrogen-independent Mammary Tumorigenesis
  Neoplasia (New York, N.Y.). Sep, 2010  |   Pubmed ID: 20824048
• Genetic Manipulation of Individual Somatic Mammary Cells in Vivo Reveals a Master Role of STAT5a in Inducing Alveolar Fate Commitment and Lactogenesis Even in the Absence of Ovarian Hormones
  Developmental Biology. Oct, 2010  |   Pubmed ID: 20691178
• Defining the ATM-mediated Barrier to Tumorigenesis in Somatic Mammary Cells Following ErbB2 Activation
  Proceedings of the National Academy of Sciences of the United States of America. Feb, 2010  |   Pubmed ID: 20133707
• Lentivirus Vectors for Stably Introducing Genes into Mammary Epithelial Cells in Vivo
  Journal of Mammary Gland Biology and Neoplasia. Dec, 2009  |   Pubmed ID: 19936990
• The RCAS-TVA System for Introduction of Oncogenes into Selected Somatic Mammary Epithelial Cells in Vivo
  Journal of Mammary Gland Biology and Neoplasia. Dec, 2009  |   Pubmed ID: 19936988
• Scaffold Attachment Factor B1 (SAFB1) Heterozygosity Does Not Influence Wnt-1 or DMBA-induced Tumorigenesis
  Molecular Cancer. Mar, 2009  |   Pubmed ID: 19267898
• Lentivirus-mediated Oncogene Introduction into Mammary Cells in Vivo Induces Tumors
  Neoplasia (New York, N.Y.). Jul, 2008  |   Pubmed ID: 18592025
• Comparison of Expression Profiles of Metastatic Versus Primary Mammary Tumors in MMTV-Wnt-1 and MMTV-Neu Transgenic Mice
  Neoplasia (New York, N.Y.). Feb, 2008  |   Pubmed ID: 18283333
• RCAS-TVA in the Mammary Gland: an in Vivo Oncogene Screen and a High Fidelity Model for Breast Transformation?
  Cell Cycle (Georgetown, Tex.). Apr, 2007  |   Pubmed ID: 17377492
• Wnt-1 is Dominant over Neu in Specifying Mammary Tumor Expression Profiles
  Technology in Cancer Research & Treatment. Dec, 2006  |   Pubmed ID: 17121432
• Introduction of Oncogenes into Mammary Glands in Vivo with an Avian Retroviral Vector Initiates and Promotes Carcinogenesis in Mouse Models
  Proceedings of the National Academy of Sciences of the United States of America. Nov, 2006  |   Pubmed ID: 17090666
• A Pivotal Role for Endogenous TGF-beta-activated Kinase-1 in the LKB1/AMP-activated Protein Kinase Energy-sensor Pathway
  Proceedings of the National Academy of Sciences of the United States of America. Nov, 2006  |   Pubmed ID: 17085580
• Keratin 6 is Not Essential for Mammary Gland Development
  Breast Cancer Research : BCR. 2006  |   Pubmed ID: 16790075
• Stem/progenitor Cells in Mouse Mammary Gland Development and Breast Cancer
  Journal of Mammary Gland Biology and Neoplasia. Jan, 2005  |   Pubmed ID: 15886883
• Estrogen Receptor Positivity in Mammary Tumors of Wnt-1 Transgenic Mice is Influenced by Collaborating Oncogenic Mutations
  Oncogene. Jun, 2005  |   Pubmed ID: 15824740
• Determinants of Cardiac Electrophysiological Properties in Mice
  Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing. Aug, 2004  |   Pubmed ID: 15273447
• Disruption of Rho Signaling Results in Progressive Atrioventricular Conduction Defects While Ventricular Function Remains Preserved
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. May, 2004  |   Pubmed ID: 15033930