Xiao-Yu Tian School of Biomedical Sciences, Institute of Vascular Medicine, Li Ka Shing Institute of Health Sciences Chinese University of Hong Kong Biography Publications Institution JoVE Articles Xiao-Yu Tian has not added a biography. If you are Xiao-Yu Tian and would like to personalize this page please email our Author Liaison for assistance. Publications Uncoupling Protein 2 in Cardiovascular Health and Disease Frontiers in Physiology. 2018 | Pubmed ID: 30116205 Regulatory T Cells Promote Apelin-Mediated Sprouting Angiogenesis in Type 2 Diabetes Cell Reports. Aug, 2018 | Pubmed ID: 30089270 Recent Advances in Managing Atherosclerosis Via Nanomedicine Small (Weinheim an Der Bergstrasse, Germany). Jan, 2018 | Pubmed ID: 29239134 Inhibition of MiR-92a Suppresses Oxidative Stress and Improves Endothelial Function by Upregulating Heme Oxygenase-1 in Db/db Mice Antioxidants & Redox Signaling. 02, 2018 | Pubmed ID: 28683566 Comprehensive Analysis of Acylcarnitine Species in Db/db Mouse Using a Novel Method of High-Resolution Parallel Reaction Monitoring Reveals Widespread Metabolic Dysfunction Induced by Diabetes Analytical Chemistry. Oct, 2017 | Pubmed ID: 28859482 Generation of Human Liver Chimeric Mice with Hepatocytes from Familial Hypercholesterolemia Induced Pluripotent Stem Cells Stem Cell Reports. 03, 2017 | Pubmed ID: 28262545 Myeloid Deletion Increases Monocyte Recruitment and Worsens Atherosclerosis FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. 03, 2017 | Pubmed ID: 27927724 PPARδ Is Required for Exercise to Attenuate Endoplasmic Reticulum Stress and Endothelial Dysfunction in Diabetic Mice Diabetes. 02, 2017 | Pubmed ID: 27856609 Integrin-YAP/TAZ-JNK Cascade Mediates Atheroprotective Effect of Unidirectional Shear Flow Nature. Dec, 2016 | Pubmed ID: 27926730 Reactive Oxygen Species, Endoplasmic Reticulum Stress and Mitochondrial Dysfunction: The Link with Cardiac Arrhythmogenesis Frontiers in Physiology. 2016 | Pubmed ID: 27536244 Melamine Impairs Renal and Vascular Function in Rats Scientific Reports. 06, 2016 | Pubmed ID: 27324576 E-selectin-targeting Delivery of MicroRNAs by Microparticles Ameliorates Endothelial Inflammation and Atherosclerosis Scientific Reports. Mar, 2016 | Pubmed ID: 26956647 Bone Morphogenic Protein 4-Smad-Induced Upregulation of Platelet-Derived Growth Factor AA Impairs Endothelial Function Arteriosclerosis, Thrombosis, and Vascular Biology. Mar, 2016 | Pubmed ID: 26769046 Chronic Black Tea Extract Consumption Improves Endothelial Function in Ovariectomized Rats European Journal of Nutrition. Aug, 2016 | Pubmed ID: 26276555 A Revisit on the Renin-angiotensin System in Cardiovascular Biology Trends in Cardiovascular Medicine. Apr, 2016 | Pubmed ID: 26212445 Black Tea Protects Against Hypertension-associated Endothelial Dysfunction Through Alleviation of Endoplasmic Reticulum Stress Scientific Reports. May, 2015 | Pubmed ID: 25976123 Upregulation of Angiotensin (1-7)-Mediated Signaling Preserves Endothelial Function Through Reducing Oxidative Stress in Diabetes Antioxidants & Redox Signaling. Oct, 2015 | Pubmed ID: 25867182 Unconjugated Bilirubin Mediates Heme Oxygenase-1-induced Vascular Benefits in Diabetic Mice Diabetes. May, 2015 | Pubmed ID: 25475440 The Peroxisome Proliferator-activated Receptors in Cardiovascular Diseases: Experimental Benefits and Clinical Challenges British Journal of Pharmacology. Dec, 2015 | Pubmed ID: 25438608 Rosiglitazone Attenuated Endothelin-1-Induced Vasoconstriction of Pulmonary Arteries in the Rat Model of Pulmonary Arterial Hypertension Via Differential Regulation of ET-1 Receptors PPAR Research. 2014 | Pubmed ID: 24701204 Metformin Protects Endothelial Function in Diet-induced Obese Mice by Inhibition of Endoplasmic Reticulum Stress Through 5' Adenosine Monophosphate-activated Protein Kinase-peroxisome Proliferator-activated Receptor δ Pathway Arteriosclerosis, Thrombosis, and Vascular Biology. Apr, 2014 | Pubmed ID: 24482374 Uncoupling Protein-2 Mediates DPP-4 Inhibitor-induced Restoration of Endothelial Function in Hypertension Through Reducing Oxidative Stress Antioxidants & Redox Signaling. Oct, 2014 | Pubmed ID: 24328731 Inhibition of Bone Morphogenic Protein 4 Restores Endothelial Function in Db/db Diabetic Mice Arteriosclerosis, Thrombosis, and Vascular Biology. Jan, 2014 | Pubmed ID: 24202302 Pleiotropic Effects of Peroxisome Proliferator-activated Receptor γ and δ in Vascular Diseases Circulation Journal : Official Journal of the Japanese Circulation Society. 2013 | Pubmed ID: 24107399 Boldine Improves Endothelial Function in Diabetic Db/db Mice Through Inhibition of Angiotensin II-mediated BMP4-oxidative Stress Cascade British Journal of Pharmacology. Nov, 2013 | Pubmed ID: 23992296 Menthol Relaxes Rat Aortae, Mesenteric and Coronary Arteries by Inhibiting Calcium Influx European Journal of Pharmacology. Feb, 2013 | Pubmed ID: 23380688 Fo Shou San, an Ancient Chinese Herbal Decoction, Protects Endothelial Function Through Increasing Endothelial Nitric Oxide Synthase Activity PloS One. 2012 | Pubmed ID: 23284736 PPARδ 激活保护血管内皮功能在糖尿病小鼠。 Diabetes. Dec, 2012 | Pubmed ID: 22933110 二肽酰肽肽酶 4 抑制剂 Sitagliptin 通过胰高血糖素样肽-1 依赖机制保护高血压病患者血管内皮功能。 Hypertension. Sep, 2012 | Pubmed ID: 22868389 慢性的酸果蔓汁消费胆固醇配置文件可恢复和改善去势大鼠血管内皮功能。 European Journal of Nutrition. Jul, 2012 | Pubmed ID: 22836513 辣椒碱降低血浆胆固醇和改善血管内皮功能的仓鼠。 European Journal of Nutrition. Mar, 2012 | Pubmed ID: 22466858 NaHS 放宽大鼠大脑中动脉体外经 L-型电压敏感经通道的抑制作用。 Pharmacological Research : the Official Journal of the Italian Pharmacological Society. Feb, 2012 | Pubmed ID: 22133671 骨形态蛋白-4 通过氧化应激相关 P38MAPK 和 JNK 通路内皮细胞凋亡。 Journal of Molecular and Cellular Cardiology. Jan, 2012 | Pubmed ID: 22064324 雷洛昔芬改善去势仓鼠喂胆固醇饮食加压间隔冠状动脉血管反应性。 Pharmacological Research : the Official Journal of the Italian Pharmacological Society. Feb, 2012 | Pubmed ID: 22005391 氧化应激相关环氧合酶-2 派生前列腺素 F(2α) 损害肾血管性高血压大鼠血管内皮功能。 Antioxidants & Redox Signaling. Feb, 2012 | Pubmed ID: 21951274 内皮细胞一氧化氮合酶剂减少了氧化应激和恢复 Db/db 小鼠血管内皮功能。 Cardiovascular Research. Nov, 2011 | Pubmed ID: 21875904 需要 PPARγ 介导改善血管内皮功能在糖尿病小鼠脂联素。 Cell Metabolism. Jul, 2011 | Pubmed ID: 21723508 高胆固醇饮食植物甾醇和其氧化产物对脂蛋白概况和仓鼠血管功能的影响。 Atherosclerosis. Nov, 2011 | Pubmed ID: 21719014 肾素-血管紧张素系统抑制的反转血管内皮功能障碍与雌激素缺乏大鼠氧化应激。 PloS One. 2011 | Pubmed ID: 21479266 AVE3085,增强内皮细胞一氧化氮合酶,恢复血管内皮功能和减少自发性高血压大鼠的血压。 British Journal of Pharmacology. Jul, 2011 | Pubmed ID: 21385179 替米沙坦抑制血管收缩通过依赖于 PPARγ 的表达和内皮细胞一氧化氮合酶的激活。 Cardiovascular Research. Apr, 2011 | Pubmed ID: 21156825 前列腺素环氧合酶-1 和-2 的舒张收缩行动不可缺少的作用。 Advances in Pharmacology (San Diego, Calif.). 2010 | Pubmed ID: 21081215 骨形态蛋白 4 损害血管内皮功能通过氧化应激相关环氧合酶-2 上调: 对高血压的影响。 Circulation Research. Oct, 2010 | Pubmed ID: 20724703 4-氨基吡啶-敏感性 K + 通道有助于 NaHS 诱导膜超极化和大鼠冠状动脉松弛。 Vascular Pharmacology. Sep-Oct, 2010 | Pubmed ID: 20430111 血管内皮功能障碍: 糖尿病和高血压的共同结果。 Journal of Cardiovascular Pharmacology. Apr, 2010 | Pubmed ID: 20422734 血管紧张素 II 1 型受体依赖氧化应激介导血管内皮功能障碍对 2 型糖尿病小鼠。 Antioxidants & Redox Signaling. Sep, 2010 | Pubmed ID: 20136508 诱导多潜能干细胞源性肝细胞的家族性高胆固醇血症人肝嵌合小鼠模型 Jiayin Yang*1,2,6, Lai-Yung Wong*2, Xiao-Yu Tian*3, Rui Wei1,2, Wing-Hon Lai2, Ka-Wing Au2, Zhiwei Luo4,5, Carl Ward4,5, Wai-In Ho2, David P. Ibañez4,5, Hao Liu4,5, Xichen Bao4,5, Baoming Qin4,5, Yu Huang3, Miguel A. Esteban4,5,7, Hung-Fat Tse1,2,6,7 1Department of Medicine, University of Hong Kong-Shenzhen Hospital, 2The Cardiology Division, Department of Medicine, Li Ka Shing Faculty of Medicine, University of Hong Kong, 3School of Biomedical Sciences, Institute of Vascular Medicine, Li Ka Shing Institute of Health Sciences, Chinese University of Hong Kong, 4Key Laboratory of Regenerative Biology of the Chinese Academy of Sciences, Joint School of Life Sciences, Guangzhou Institutes of Biomedicine and Health and Guangzhou Medical University, 5Laboratory of RNA, Chromatin, and Human Disease, CAS Key Laboratory of Regenerative Biology and Guangdong Provincial Key Laboratory of Stem Cells and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, 6Research Centre of Heart, Brain, Hormone, and Healthy Ageing, Li Ka Shing Faculty of Medicine, University of Hong Kong, 7Hong Kong-Guangdong Stem Cell and Regenerative Medicine Research Centre, University of Hong Kong and Guangzhou Institutes of Biomedicine and Health JoVE 57556 Developmental Biology
诱导多潜能干细胞源性肝细胞的家族性高胆固醇血症人肝嵌合小鼠模型 Jiayin Yang*1,2,6, Lai-Yung Wong*2, Xiao-Yu Tian*3, Rui Wei1,2, Wing-Hon Lai2, Ka-Wing Au2, Zhiwei Luo4,5, Carl Ward4,5, Wai-In Ho2, David P. Ibañez4,5, Hao Liu4,5, Xichen Bao4,5, Baoming Qin4,5, Yu Huang3, Miguel A. Esteban4,5,7, Hung-Fat Tse1,2,6,7 1Department of Medicine, University of Hong Kong-Shenzhen Hospital, 2The Cardiology Division, Department of Medicine, Li Ka Shing Faculty of Medicine, University of Hong Kong, 3School of Biomedical Sciences, Institute of Vascular Medicine, Li Ka Shing Institute of Health Sciences, Chinese University of Hong Kong, 4Key Laboratory of Regenerative Biology of the Chinese Academy of Sciences, Joint School of Life Sciences, Guangzhou Institutes of Biomedicine and Health and Guangzhou Medical University, 5Laboratory of RNA, Chromatin, and Human Disease, CAS Key Laboratory of Regenerative Biology and Guangdong Provincial Key Laboratory of Stem Cells and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, 6Research Centre of Heart, Brain, Hormone, and Healthy Ageing, Li Ka Shing Faculty of Medicine, University of Hong Kong, 7Hong Kong-Guangdong Stem Cell and Regenerative Medicine Research Centre, University of Hong Kong and Guangzhou Institutes of Biomedicine and Health JoVE 57556 Developmental Biology