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A Neonatal Heterotopic Rat Heart Transplantation Model for the Study of Endothelial-to-Mesenchymal Transition (Video) | JoVE
Surgical Preparation and Heterotopic Transplantation of the Neonatal Donor Heart in the Recipient Rat (Video) | JoVE
この研究は、重症大動脈弁狭窄症や左心低形成症候群などの先天性心疾患に見られる内皮から間葉への移行誘発性線維症の動物モデルを提示し、詳細な組織学的組織評価、調節シグナル伝達経路の同定、および治療オプションのテストを可能にします。
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