Establishment of a High-throughput Setup for Screening Small Molecules That Modulate c-di-GMP Signaling in <em>Pseudomonas aeruginosa</em>

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高通量设置的建立筛选小分子能调节C-二GMP信令<em>绿脓杆菌</em

JoVE 杂志
免疫与感染

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JoVE 杂志免疫与感染

Establishment of a High-throughput Setup for Screening Small Molecules That Modulate c-di-GMP Signaling in Pseudomonas aeruginosa

高通量设置的建立筛选小分子能调节C-二GMP信令<em>绿脓杆菌</em

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8,387 Views

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11:31 min

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June 30, 2016

DOI:

DOI:

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11:31 min

June 30, 2016

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8 Views

本文介绍了已经成功地建立筛选小分子的大文库其操纵在绿脓杆菌环状二-GMP的细胞水平的潜在能力，提供了抗菌药物发现和化合物测试一个新的强有力的工具的高通量测定法。