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An Efficient Sample Preparation Method to Enhance Carbohydrate Ion Signals in Matrix-assisted Laser Desorption/Ionization Mass Spectrometry

Article DOI: 10.3791/57660-v • 07:12 min • July 29th, 2018
July 29th, 2018 •
1,2, 1, 1, 2, 1
1Genomic Research Center, Academia Sinica, 2Department of Chemistry, National Taiwan University

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Automatic Translation

A protocol for enhancing carbohydrate ion signals in MALDI mass spectrometry by reforming crystalline structures during sample preparation processes is demonstrated.

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Efficient Sample Preparation Method Enhance Carbohydrate Ion Signals Matrix-assisted Laser Desorption/ionization Mass Spectrometry Simple Morphology Drying Process Signal Intensity Optimized Method Methanol Depressurization Data Quality Sample Plate Detergent Solution Distilled-deionized Water Methanol Rinse Ultrasonic Bath Pressurized Nitrogen Treatment Drying Chamber
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