JoVE Journal
Cancer Research
Cancer Research
需要订阅 JoVE 才能查看此 内容. 登录或开始免费试用。
章节
总结概括
Syngeneic mouse orthotopic allografts of pancreatic ductal adenocarcinoma (PDAC) recapitulate the biology, phenotypes, and therapeutic responses of disease subtypes. Owing to their fast, reproducible tumor progression, they are widely used in preclinical studies. Here, we show common practices to generate these models, injecting syngeneic murine PDAC cultures into the pancreas.