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High-throughput Synthesis of Carbohydrates and Functionalization of Polyanhydride Nanoparticles

Article DOI: 10.3791/3967-v • 14:37 min • July 6th, 2012
July 6th, 2012 •
*1, *2, *1, 1, 1,2
1Department of Chemical and Biological Engineering, Iowa State University, 2Department of Chemistry, Iowa State University
* These authors contributed equally

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Summary
Automatic Translation

In this article, a high throughput method is presented for the synthesis of oligosaccharides and their attachment to the surface of polyanhydride nanoparticles for further use in targeting specific receptors on antigen presenting cells.

Tags

High-throughput Synthesis Carbohydrates Functionalization Polyanhydride Nanoparticles Material Design Nanotechnology Chemistry Immunology Vaccine Carriers Nanoparticle-based Platforms Vaccine Antigens Biodegradable Polymers Vaccine Delivery Vehicles Sustained Release Protein Antigens Antigen Presenting Cells Immune Responses Molecular Design Polymer Properties Targeting Agents High Throughput Automated Fabrication Targeting Ligands Functionalized Particles Reproducible Vaccine Delivery Devices Specific Receptors Immune Cells C-type Lectin Receptors (CLRs) Pattern Recognition Receptors (PRRs) Carbohydrates
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