JoVE Journal
Chemistry
Chemistry
Un abonnement à JoVE est nécessaire pour afficher ce contenu.
Chapitres
résumé
A simple and general method for the synthesis of cyclic peptides using microwave irradiation is outlined. This procedure enables the synthesis of backbone cyclic peptides with a collection of different conformations while retaining the side chains and the pharmacophoric moieties., and therefore, allows to screen for the bioactive conformation.