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Rekonstruere humant retinoblastom in vitro
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Rekonstruere humant retinoblastom in vitro

Article DOI: 10.3791/62629-v • 06:52 min • October 11th, 2022
October 11th, 2022 •
1, 1
1Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Science Key Laboratory

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Vi beskriver en metode for å generere humant retinoblastom (RB) ved å introdusere bialleliske RB1-mutasjoner i humane embryonale stamceller (hESC). RB-cellelinjer kan også vellykket dyrkes ved hjelp av den isolerte RB i en tallerken.

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