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Preparation, Purification, and Characterization of Lanthanide Complexes for Use as Contrast Agents for Magnetic Resonance Imaging
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Preparation, Purification, and Characterization of Lanthanide Complexes for Use as Contrast Agents for Magnetic Resonance Imaging

Article DOI: 10.3791/2844-v • 13:22 min • July 21st, 2011
July 21st, 2011 •
*1, *1, *1, *1, 1
1Department of Chemistry, Wayne State University
* These authors contributed equally

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We demonstrate the metalation, purification, and characterization of lanthanide complexes. The complexes described here can be conjugated to macromolecules to enable tracking of these molecules using magnetic resonance imaging.

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Preparation Purification Characterization Lanthanide Complexes Contrast Agents Magnetic Resonance Imaging Polyaminopolycarboxylate-based Ligands Chelate Functional Groups Conjugation Amine-reactive Activated Esters Isothiocyanate Groups Thiol-reactive Maleimides Metalation Procedures Metal Starting Materials Purification Methods Biomedical Scientists
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