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Enzymatisk syntese av Epoxidized metabolitter av dokosaheksaensyre, eikosapentaensyre, og arachidonic syrer

Article DOI: 10.3791/59770-v • 13:05 min • June 28th, 2019
June 28th, 2019 •
1, 1, 1, 1
1Department of Pharmacology and Toxicology, Michigan State University

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Vi presenterer en metode nyttig for storstilt enzymatisk syntese og rensing av spesifikke enantiomerer og regioisomers av epoksider av arachidonic syre (AA), dokosaheksaensyre syre (DHA), og eikosapentaensyre acid (EPA) med bruk av en bakteriell cytokrom P450 enzym (BM3).

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Kjemi epoxy flerumettede fettsyrer lipider enzymatisk syntese enantioselective syntese Omega-3 fettsyrer eicosanoids
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