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Journal / Cancer Research / Translationale orthotope Modelle des Glioblastoma …
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Translationale orthotope Modelle des Glioblastoma multiforme
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Translationale orthotope Modelle des Glioblastoma multiforme

Article DOI: 10.3791/64482-v • 07:37 min • February 17th, 2023
February 17th, 2023 •
1, 1, 1
1Center for Advanced Preclinical Research, Frederick National Laboratory for Cancer Research, National Cancer Institute

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In dieser Arbeit beschreiben wir ein präklinisches orthotopes Mausmodell für GBM, das durch intrakranielle Injektion von Zellen aus gentechnisch veränderten Mausmodelltumoren etabliert wurde. Dieses Modell zeigt die Krankheitsmerkmale des humanen GBM. Für translationale Studien wird der Hirntumor der Maus mittels In-vivo-MRT und Histopathologie verfolgt.

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