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JoVE Journal Neuroscience
Chirurgie und Verhaltenstests im Tibianeurom-Transpositionsmodell bei Ratten
Establishing a Mouse Model of a Pure Small Fiber Neuropathy with the Ultrapotent Agonist of Transient Receptor Potential Vanilloid Type 1
Journal (Neuroscience)
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Lateral Diffusion and Exocytosis of Membrane Proteins in Cultured Neurons Assessed using Fluorescence Recovery and Fluorescence-loss Photobleaching
Journal (Neuroscience)
Lateral Diffusion and Exocytosis of Membrane Proteins in Cultured Neurons Assessed using Fluorescence Recovery and Fluorescence-loss Photobleaching
 
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Chirurgie und Verhaltenstests im Tibianeurom-Transpositionsmodell bei Ratten

Article DOI: 10.3791/64659-v • 07:23 min • January 6th, 2023
January 6th, 2023 •
1, 2, 3, 1
1Department of Plastic and Reconstructive Surgery, University Medical Center Utrecht, Utrecht University, 2Axogen, 3Center for Translational Immunology, University Medical Center Utrecht, Utrecht University

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Dieses Protokoll beschreibt das Transpositionsmodell des Tibianeuroms, das eine Läsion des Nervus tibialis mit anschließender Transposition des proximalen Nervenendes in eine subkutane prätibiale oder laterale Position beinhaltet. Die Verhaltensdiagnostik von Neuromschmerzen und Plantarhyperalgesie wird mit Hilfe von Von-Frey-Monofilamenten quantifiziert.

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Neurowissenschaften Ausgabe 191
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