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Let forberedelse og fotoaktivering af prodrug-dye nanosamlinger
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Let forberedelse og fotoaktivering af prodrug-dye nanosamlinger

Article DOI: 10.3791/64677-v • 08:54 min • February 17th, 2023
February 17th, 2023 •
1,2,3, 1,2,3, 1,2,3
1State Key Laboratory of Pharmaceutical Biotechnology, The University of Hong Kong, 2Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, 3Laboratory of Molecular Engineering and Nanomedicine, Dr. Li Dak-Sum Research Centre, The University of Hong Kong

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Denne protokol beskriver fremstillingen og karakteriseringen af en fotoresponsiv prodrug-dye nanoassembly. Metoden til lægemiddelfrigivelse fra nanopartiklerne ved lysudløst demontering, herunder lysbestrålingsopsætningen, er eksplicit beskrevet. De lægemidler, der blev frigivet fra nanopartiklerne efter lysbestråling, udviste fremragende antispredningsvirkninger på humane kolorektal tumorceller.

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Medicin nr. 192
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