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JoVE Journal Behavior
Adfærdsmæssige vurderinger af spontan bevægelse i en Murine MPTP-induceret Parkinsons sygdom Model
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Adfærdsmæssige vurderinger af spontan bevægelse i en Murine MPTP-induceret Parkinsons sygdom Model

Article DOI: 10.3791/58653-v • 05:38 min • January 7th, 2019
January 7th, 2019 •
1, 1, 1, 1, 1, 1, 1
1State Key Laboratory of Medicinal Chemical Biology, The Key Laboratory of Bioactive Materials, Ministry of Education, College of Life Science, Nankai University

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Vi beskriver etableringen af en murine model for Parkinsons sygdom ved hjælp af MPTP og adfærdsmæssige vurderinger ved hjælp af cylinder og open field test til at måle motorik. Vi derefter bruge L-DOPA som et eksempel til at vise, hvordan at anvende denne model i studiet af PD narkotika.

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Adfærd spørgsmålet 143 Parkinsons sygdom MPTP adfærdsmæssige test cylinder test open field test dyremodel
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