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JoVE Journal Cancer Research
Портальная инъекция органоидов колоректального рака для изучения стромы метастазов в печень
Four-color Fluorescence Immunohistochemistry of T-cell Subpopulations in Archival Formalin-fixed, Paraffin-embedded Human Oropharyngeal Squamous Cell Carcinoma Samples
Journal (Cancer Research)
Four-color Fluorescence Immunohistochemistry of T-cell Subpopulations in Archival Formalin-fixed, Paraffin-embedded Human Oropharyngeal Squamous Cell Carcinoma Samples
Generating and Imaging Mouse and Human Epithelial Organoids from Normal and Tumor Mammary Tissue Without Passaging
Journal (Cancer Research)
Generating and Imaging Mouse and Human Epithelial Organoids from Normal and Tumor Mammary Tissue Without Passaging
 
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Портальная инъекция органоидов колоректального рака для изучения стромы метастазов в печень

Article DOI: 10.3791/62630-v • 07:59 min • September 3rd, 2021
September 3rd, 2021 •
1,2,3,4, 1,2, 1,2, 1,2, 1,2, 1,2, 1,2, 1,2, 1,2,5, 1,2, 2, 1,2, 6, 3,4,7, 3, 2, 1,2
1Adelaide Medical School, University of Adelaide, 2South Australian Health and Medical Research Institute (SAHMRI), 3Department of Pathology, Nagoya University Graduate School of Medicine, 4Division of Molecular Pathology, Center for Neurological Disease and Cancer, Nagoya University Graduate School of Medicine, 5Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, 6Translational and Clinical Research Institute, Newcastle University, 7International Center for Cell and Gene Therapy, Fujita Health University

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Инъекция органоидов колоректального рака (CRC) в воротную вену генерирует богатые стромой метастазы в печень. Эта мышиная модель метастазирования печени CRC представляет собой полезный инструмент для изучения взаимодействий опухоли и стромы и разработки новых терапевтических средств, направленных на строму, таких как генная терапия, опосредованная аденоассоциированным вирусом.

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Исследования рака выпуск 175
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